Курский научно-практический вестник «Человек и его здоровье»最新文献

{"title":"Arterial stiffness in patients with acute coronary syndrome without persistent ST segment elevation combined with chronic kidney disease and arterial hypertension and its correction with antihypertensive therapy","authors":"Pribylov Sergey A., Yakovleva Margarita V., Pribylov Vladislav S., Barbashina Tatiana A., Leonidova Kristina O., Pribylova Nadezda N.","doi":"10.21626/vestnik/2022-1/03","DOIUrl":"https://doi.org/10.21626/vestnik/2022-1/03","url":null,"abstract":"Objective: to study arterial stiffness in patients with acute coronary syndrome without ST elevation, who have hypertension (AH) and stage 2-3A chronic kidney disease (CKD) and to assess the ability of angiotensin-converting enzyme inhibitor perindopril and angiotensin receptor antagonist losartan to reduce arterial stiffness in these patients. Materials and Methods. We studied 44 patients with ACS without ST elevation combined with CKD stage 2-3A, AH (the 1st group). The comparison groups were the ACS without ST segment elevation, AH patients with normal renal function (the 2nd group, n=27) and the 3rd group (n=44) of patients with chronic CHD, AH and CKD. Group 1 patients were divided into 2 subgroups taking perindopril or losartan. The parameters of vascular wall stiffness (pulse wave velocity (PWV), cardio-ankle vascular index (CAVI), ankle brachial index (ABI), aortic augmentation index (AI), central systolic and pulse aortic pressure, peripheral blood pressure (BP), estimated glomerular filtration rate (GFR) were assessed.) Results. The patients with ACS without ST elevation combined with 2-3A stages of CKD and AH had a significantly higher cPAP, AI, PWV, and CAVI than the patients of the 2nd group. During 3 months of complex therapy with perindopril, a decrease in PWV, cSAP, cPAP, AI was observed. There were no significant differences in the effects of perindopril and losartan on peripheral and central blood pressure, on renal function, on arterial stiffness parameters. Conclusion. Patients with AH and CKD stage 2-3A have more pronounced arterial stiffness compared to similar patients with normal GFR. Antihypertensive therapy with perindopril and losartan allows to reach target levels of peripheral BP, significantly reduce central aortic pressure and improve elastic properties of the arterial vascular wall.","PeriodicalId":24060,"journal":{"name":"Курский научно-практический вестник «Человек и его здоровье»","volume":"136 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76389166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of polysaccharides of common raspberry shoots and their sorption activity","authors":"D. K. Gulyaev, V. D. Belonogova, I. P. Rudakova, I. V. Korotkov","doi":"10.21626/vestnik/2022-3/08","DOIUrl":"https://doi.org/10.21626/vestnik/2022-3/08","url":null,"abstract":"A comparative study of the water-soluble polysaccharide complex and pectin substances of first and second year shoots of common raspberry. Objective - comparative study and sorption activity of polysaccharides of common raspberry shoots. Materials and methods. The samples for the research were collected in a dark coniferous forest on the territory of the Ilyinsky district of Perm Region. The content of polysaccharide fractions was determined by the modified Dreywood anthrone- sulfurous method. A water-soluble polysaccharide complex and pectin substances were sequentially obtained from different parts of the shoots. The sorption activity was determined by the ability of the substances to bind methylene blue, which is a marker for most medical sorbents. The acute toxicity of the obtained polysaccharide fractions was examined according to Prozorovsky V.V. Results. The shoots of the first and second year of common raspberry accumulate more pectin substances than water-soluble polysaccharides. Leaves of raspberry contain more polysaccharides compared to leafless parts. As a result of acute toxicity study, it was found that all studied substances can be classified as low-toxic (LD50>5,000 mg/kg). It was found that water-soluble polysaccharide complex obtained from leafless parts of the shoot of the first and second year shows sorption activity reliably higher than that of the reference preparation (Polyphepan). Sorption activity of pectin substances obtained from leaves of the first and second year shoots also exceeds that of the reference preparation. The highest sorption activity is shown by pectin substances of the second year, and the lowest sorption activity by pectin substances of leafless raspberry shoots. Conclusion. The obtained substances are promising for creating modern sorbents based on polysaccharide fractions of the first and second year shoots of common raspberry. Taking into account the simplicity in harvesting and high sorption activity of polysaccharides of the leafless part of the raspberry shoot, not only leaves but also leafless parts of the shoot should be harvested.","PeriodicalId":24060,"journal":{"name":"Курский научно-практический вестник «Человек и его здоровье»","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85770353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EVALUATION OF THE STATE OF THE OPERATIONAL EFFICIENCY OF TIMBER TRUCKS WITH RELEASE TRAILERS","authors":"V. Posmetev, V. Nikonov","doi":"10.58168/prtow2022_37-56","DOIUrl":"https://doi.org/10.58168/prtow2022_37-56","url":null,"abstract":"","PeriodicalId":24060,"journal":{"name":"Курский научно-практический вестник «Человек и его здоровье»","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72937464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiological mechanisms of action of vitamin D in oral tissues and organs and the possibility of its use in preventive dentistry (literature review)","authors":"N. G. Sarkisyan, E. Gaisina, M. Dobrinskaya, Arina D. Pototskaya","doi":"10.21626/vestnik/2022-3/05","DOIUrl":"https://doi.org/10.21626/vestnik/2022-3/05","url":null,"abstract":"Vitamin D has a variety of effects on oral tissues and organs. Cholecalciferol is involved in the processes of formation of enamel and dentin, metabolism of jaw bone tissue, local immunity and antitumor reactions. The functional features of the vitamin D effects reveal the possibility of dental pathology prevention. Objective. To study the literature data on the effect of vitamin D on oral tissues and organs and the possibility of using vitamin D as a drug in the prevention of dental diseases. Materials and methods. The review and analysis of literary sources was carried out by keywords on the electronic resources of the Scopus, Web of Science, MedLine, The Cochrane Library, RSCI databases. Russian and foreign sources were used. The literature review was conducted between August 2021 and March 2022. Results. Randomized studies prove that receptors for vitamin D (colecalciferol) are found on the surface of almost all cells, which explains the pleiotropic effect of vitamin D on the human body. Colecalciferol is involved in the formation of substitutive dentin in the foci of demineralization. The active metabolite of vitamin D has an antitumor effect on the oral tissues, anti-inflammatory and antimicrobial action in periodontal disease. Colecalciferol influences osseointegration during implantation, the processes of osteogenesis and osteolysis during orthodontic treatment. Conclusion. Vitamin D has effects on various tissues and organs of the oral cavity, which gives the possibility to include cholecalciferol in clinical guidelines for dental diseases prophylaxis.","PeriodicalId":24060,"journal":{"name":"Курский научно-практический вестник «Человек и его здоровье»","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77612778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Психолого-педагогические условия приобщения к здоровому образу жизни детей школьного возраста в рамках проекта «Укрепление и сохранение здоровья детей, вовлечение учащихся в систематические занятия физической культурой во вне-урочное время»","authors":"N. Maksimova","doi":"10.52376/978-5-907541-95-5_139","DOIUrl":"https://doi.org/10.52376/978-5-907541-95-5_139","url":null,"abstract":"","PeriodicalId":24060,"journal":{"name":"Курский научно-практический вестник «Человек и его здоровье»","volume":"138 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77422707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SUBSTANTIATION OF THE TECHNOLOGY OF DIAGNOSTICS OF VEHICLE TRANSMISSION","authors":"V. I. Vergun","doi":"10.58168/prtow2022_9-14","DOIUrl":"https://doi.org/10.58168/prtow2022_9-14","url":null,"abstract":"","PeriodicalId":24060,"journal":{"name":"Курский научно-практический вестник «Человек и его здоровье»","volume":"214 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77558795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Работа социального педагога по профилактике агрессивного поведения подростков в условиях общеобразовательной школы","authors":"Aiiina Ivanova, R. Gerasimova","doi":"10.52376/978-5-907541-95-5_193","DOIUrl":"https://doi.org/10.52376/978-5-907541-95-5_193","url":null,"abstract":"","PeriodicalId":24060,"journal":{"name":"Курский научно-практический вестник «Человек и его здоровье»","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76896277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"METHOD OF TESTING FOR WEAR DURING PLANE-PARALLEL MOVEMENT","authors":"V. Bukhtoyarov, V. Ivannikov, A. Golev, I.O. Kashirin","doi":"10.58168/prtow2022_73-79","DOIUrl":"https://doi.org/10.58168/prtow2022_73-79","url":null,"abstract":"","PeriodicalId":24060,"journal":{"name":"Курский научно-практический вестник «Человек и его здоровье»","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83158879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphoscopic and morphometric characteristics of the LV-SI intervertebral disc in young and middle-aged individuals","authors":"Maksim A. Priymak, Aleksey I. Gaivoronsky, I. V. Gaivoronsky, G. I. Nichiporuk, I. A. Goryacheva, M. G. Gaivoronskaya","doi":"10.21626/vestnik/2022-4/10","DOIUrl":"https://doi.org/10.21626/vestnik/2022-4/10","url":null,"abstract":"Objective: to study the morphoscopic and morphometric characteristics of the LV-SI intervertebral disc according to magnetic resonance imaging. Materials and methods. The analysis of magnetic resonance imaging of 90 patients (66 men, 24 women) who did not have diseases of the lumbar spine was performed. Various morphometric parameters of the intervertebral disc (IVD) and nucleus pulposus (NP) at the LV-SI level were measured using software for processing images created on an MRI machine. The obtained data were compared between men and women, asthenics, normosthenics, hypersthenics and young (from 18 to 44 years old) and middle-aged (from 45 to 60 years old) people. In addition, morphoscopic characteristics were studied: the shape of the IVD and NP in the axial plane. Results. It was found that in normal IVD LV-SI is most often represented by elliptical (54,5%) less often kidney-shaped (45,5%) forms. Normally, the NP has an oval (57,8%) and kidney-shaped (42,2%) shape. It was shown that in men, the dorsal height of the IVD, its width, anteroposterior size, square as well as the longitudinal-transverse index of the NP were significantly higher. It has been proven that there are no significant differences in the shape of the IVD between asthenics, normo- and hypersthenics, while the height of the IVD in the center, its ventral, dorsal heights and most lateral IVD height are significantly greater in hypersthenics. It has been proved that the kidney-shaped form of NP was significantly more common in asthenics, and the oval form - in hypersthenics, while the morphometric parameters of NP did not significantly differ between extreme body types. A tendency to a decrease in IVD height in middle-aged people compared to young people was shown. Conclusion. The results obtained are necessary when planning the operation, as well as for the manufacture of rigid implants and artificial discs for arthroplasty and interbody fusion.","PeriodicalId":24060,"journal":{"name":"Курский научно-практический вестник «Человек и его здоровье»","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79964225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of complex medications to treat patients with back pain","authors":"Shuteeva Elena Yu., Krapiva Anna B., Shuteeva Tatiana V.","doi":"10.21626/vestnik/2022-1/04","DOIUrl":"https://doi.org/10.21626/vestnik/2022-1/04","url":null,"abstract":"Purpose of the study: to assess the dynamics of pain indicators and various characteristics of the quality of life in patients with back pain when using a one-course treatment complex with the use of Clodifen Neuro. Materials and methods. The study included men and women aged 44 to 52 years with complaints of lower back pain caused by exacerbation of chronic dorsalgia. The main group included 30 patients (14 men and 16 women). The control group consisted of 24 patients (12 men and 12 women). The groups were comparable in terms of the severity of symptoms and the length of the disease. All patients received muscle relaxants and gastroprotectors of the corresponding pharmacological groups, patients in the main group received Clodifen Neuro 1 capsule twice a day for 2 weeks, patients in the control group received diclofenac tablets (enteric form) 50 mg twice a day. The effectiveness of therapy was assessed using the VAS scale and the Oswestry questionnaire. Assessment of the condition of patients in both groups was carried out before the start of the study, after the end of treatment (after 14 days) and 2 months after the end of therapy. Results. The study of the effectiveness of the use of Clodifen Neuro showed that in patients with chronic back pain, the drug favored a decrease in pain syndrome, an increase in the mobility of the spine, and the functional potential of patients. Conclusion. Treatment with Clodifen Neuro for 14 days (1 capsule orally 2 times a day) as a part of complex therapy contributed to a steady reduction in pain in the study group of patients with chronic back pain. The analgesic effect persisted for 2 months after the end of therapy. Clodifen Neuro can be recommended as a polytropic agent in the complex therapy of chronic back pain.","PeriodicalId":24060,"journal":{"name":"Курский научно-практический вестник «Человек и его здоровье»","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89592968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}