Zhonghua nan ke xue = National journal of andrology Pub Date : 2024-04-01

Dao-Yuan Hu, Heng-Jun Xiao

引用次数: 0

[Transrectal ultrasonography of intravesical prostatic protrusion and the detection rate of clinically significant prostate cancer]. [膀胱内前列腺突出的经直肠超声波检查和有临床意义的前列腺癌的检出率]。

Zhonghua nan ke xue = National journal of andrology Pub Date : 2024-04-01

Yun Dai, Ying-Dong Xie, Chao-Li Xu, Bin Yang

{"title":"[Transrectal ultrasonography of intravesical prostatic protrusion and the detection rate of clinically significant prostate cancer].","authors":"Yun Dai, Ying-Dong Xie, Chao-Li Xu, Bin Yang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the value of transrectal ultrasonography (TRUS) in the detection of clinically significant prostate cancer (CsPCa) in patients with intravesical prostatic protrusion (IPP).Methods: We retrospectively analyzed the data on 128 patients undergoing TRUS-guided prostate biopsy in the General Hospital of Eastern Theater Command and Jiangsu Province Hospital from January 2019 to December 2022. We measured the size of and graded IPP, compared the clinicopathological and ultrasonographic features of the patients in the CsPCa group (Gleason score ≥7) and those in the control group (Gleason score <7), and analyzed the correlation of the IPP grades with the detection rate of CsPCa by multivariate logistic regression analysis.Results: The prostate volume was significantly higher in the CsPCa group than in the control (［51.3±12.1］ vs ［43.5±11.3］ ml, P< 0.05), while the PSA density (PSAD) remarkably lower in the former than in the latter (［0.45±1.92］ vs ［0.59±2.14］ ng/ml, P< 0.05) and so was the detection rate of CsPCa in the patients with IPP grade 3 than in those with IPP grades 0, 1 and 2 (56.0% vs 85.4%, 87.1% and 80.6%, P< 0.05). Spearman correlation analysis showed that the Gleason score was correlated positively with the prostate volume (r = 0.612) but negatively with PSAD (r = －0.735) and the IPP grade (r = －0.619) (P< 0.05). Logistic regression analysis indicated that IPP grade 3 (OR: 0.690, 95% CI: 0.380－0.995, P = 0.032) was an independent protective factor for CsPCa.Conclusion: CsPCa is significantly correlated with the IPP grade, and the detection rate of CsPCa by TRUS-guided biopsy is lower in patients with IPP grade 3 than in those with IPP grades 0－2. Therefore, special attention should be paid to false negative probability in case of high-grade IPP.","PeriodicalId":24012,"journal":{"name":"Zhonghua nan ke xue = National journal of andrology","volume":"30 4","pages":"326-330"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142112769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Comprehensive intervention combined with cognitive psychological care based on quality chain for patients with benign prostatic hyperplasia]. [基于质量链的良性前列腺增生患者综合干预与认知心理护理相结合]。

Zhonghua nan ke xue = National journal of andrology Pub Date : 2024-04-01

Wen-Zhen Shi, Hong-Yun Chen, Fen Wang

{"title":"[Comprehensive intervention combined with cognitive psychological care based on quality chain for patients with benign prostatic hyperplasia].","authors":"Wen-Zhen Shi, Hong-Yun Chen, Fen Wang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the application effect of comprehensive intervention combined with cognitive psychological care based on the quality chain in patients with BPH.Methods: We prospectively selected 110 cases of BPH treated in our hospital from January 2022 to March 2023 and equally randomized them into groups A and B, the former given routine intervention, while the latter comprehensive intervention combined with cognitive psychological care based on the quality chain in addition. We analyzed the results of intervention, the patients' scores on Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS), improvement of clinical indicators, self-efficacy, disease awareness and treatment compliance, and compared the data obtained between the two groups of patients.Results: The effectiveness of intervention was significantly better in group B than in A (96.36% vs 65.45%, χ2 = 17.009, P<0.05). Compared with the baseline, the SAS and SDS scores were remarkably improved in the two groups after intervention (P<0.05), even more significantly in group B than in A (P<0.05). Group B also showed a markedly shorter duration of bladder spasm, lower frequency of bladder spasm per day, shorter urethral catheterization time and postoperative hospital stay, better emotion control and health management, more regular schedule, higher disease knowledge awareness, and better treatment compliance than group A (all P<0.05).Conclusion: Comprehensive intervention combined with cognitive psychological care based on the quality chain is significantly effective in improving BPH patients' clinical indicators, disease awareness and treatment compliance, reducing their depression and anxiety, and enhancing their self-efficacy management.","PeriodicalId":24012,"journal":{"name":"Zhonghua nan ke xue = National journal of andrology","volume":"30 4","pages":"331-335"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142112761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Status quo of ED-related studies in China: A bibliometric analysis]. [中国 ED 相关研究的现状：文献计量分析]。

Zhonghua nan ke xue = National journal of andrology Pub Date : 2024-04-01

Jia-Cheng Yu, Xiao-du Xie, Pei-He Liang

{"title":"[Status quo of ED-related studies in China: A bibliometric analysis].","authors":"Jia-Cheng Yu, Xiao-du Xie, Pei-He Liang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To summarize and visualize the status quo, future hotspots and development trend of ED-related researches in China through bibliometric analysis.Methods: We searched the Web of Science Core Collection (WOSCC) and the database of Chinese National Knowledge Infrastructure (CNKI) for ED-related studies published in China from January 1, 2010 to August 14, 2023. Using the CiteSpace and VOSviewer softwares, we bibliometrically analyzed and visualized the related journals, regions, institutions, authors, key words, co-citations and other indexes of the identified studies.Results: A total of 2,465 ED-related studies were retrieved, with an increasing number of publications year by year, relatively more in the southeast region, with Sun Yat-sen University ranking the first in the number of published articles (n = 169), LIU Jihong (n = 73), WANG Tao (n = 71) and JIANG Rui (n = 49) as the top three prolific core authors. The first two Chinese journals with the most ED-related publications were Chinese Journal of Andrology (n = 320) and Journal of Sexual Medicine (n = 128), and the latter was also the mostly cited (n = 5 060). Keyword co-occurrence analysis showed that the highest-frequency Chinese terms included impotence, anxiety, andrology, expert consensus, experience of famous doctors, acupuncture, Earthworm protein (Chinese) and hypertension, and the English terms included erectile dysfunction, apoptosis, inflammation, fibrosis, risk and women.Conclusion: Recent years have wit-nessed a rapid development in ED-related studies in China, with the risk factors and patho-genic mechanisms of ED as hot topics. PDE5 inhibitors and adipose-derived stem cells for the treatment of ED have attracted long and continuous attention and will remain an important target of future research.","PeriodicalId":24012,"journal":{"name":"Zhonghua nan ke xue = National journal of andrology","volume":"30 4","pages":"342-354"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142112768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Causal relationship between obesity and male infertility: A two-sample Mendelian randomization study]. [肥胖与男性不育之间的因果关系：双样本孟德尔随机研究]。

Zhonghua nan ke xue = National journal of andrology Pub Date : 2024-04-01

Zhi-Chao Li, Zhi-Hai Teng, Zhen-Wei Han, Yan-Ping Zhang, Cheng-Gen Jin, Ya-Xuan Wang

{"title":"[Causal relationship between obesity and male infertility: A two-sample Mendelian randomization study].","authors":"Zhi-Chao Li, Zhi-Hai Teng, Zhen-Wei Han, Yan-Ping Zhang, Cheng-Gen Jin, Ya-Xuan Wang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To clarify the causal relationship between obesity and male infertility through Mendelian randomization (MR) study.Methods: We assessed the causal effect of genetically predicted body mass index (BMI) on the risk of male infertility via a two-sample MR analysis, with the BMIs of 99 998 cases and 12 746 controls as the exposure factor and genetic information on male infertility obtained from a genome-wide association study of 73 479 Europeans. In the univariable MR (UVMR) analysis of the causal relationship, we mainly used inverse variance weighting (IVW), with MR-Egger regression and weighted median filtering as the supplementary methods. Sensitivity analyses including the Cochran's Q test, Egger intercept test, MR-PRESSO, leave-one-out analysis and funnel plot were performed to verify the robustness of the MR results. To evaluate the direct causal effects of BMI on MI risk, multivariable MR (MVMR) was performed.Results: UVMR indicated a causal relationship between genetically predicted BMI and an increased risk of male infertility (OR: 1.237, 95% CI: 1.090－1.404, P = 0.001). Sensitivity analysis revealed little evidence of bias in the current study (P> 0.05). With such risk factors as type 2 diabetes, alcohol consumption and smoking adjusted, MVMR confirmed a direct causal effect of genetically predicted BMI on the risk of male infertility (P<0.05).Conclusion: Genetically predicted BMI may be associated with an increased risk of male infertility. Further studies are expected to explore the underlying mechanisms of this association and provide some new strategies for the prevention and treatment of BMI-related male infertility.","PeriodicalId":24012,"journal":{"name":"Zhonghua nan ke xue = National journal of andrology","volume":"30 4","pages":"306-314"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142112759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Omega-3 polyunsaturated fatty acids for the treatment of oligoasthenozoospermia: Progress in research]. [奥米加-3 多不饱和脂肪酸治疗少精症：研究进展]。

Zhonghua nan ke xue = National journal of andrology Pub Date : 2024-04-01

Zhou Li, Jun Jing, Xue-Jun Shang, Bing Yao

引用次数: 0

[Causes of missed diagnosis of clinically significant prostate cancer by targeted biopsy]. [靶向活检漏诊有临床意义的前列腺癌的原因]。

Zhonghua nan ke xue = National journal of andrology Pub Date : 2024-04-01

He-Song Jiang, Shan Zhou, Xiao-Bing Niu, Lu Ji

{"title":"[Causes of missed diagnosis of clinically significant prostate cancer by targeted biopsy].","authors":"He-Song Jiang, Shan Zhou, Xiao-Bing Niu, Lu Ji","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To retrospectively analyze the causes of missed diagnosis of clinically significant PCa (csPCa) by targeted biopsy (TB).Methods: This retrospective study included 652 males aged (71.32 ± 16.53) years with elevated PSA and abnormal MRI signals detected in our hospital from June 2018 to December 2020. We further examined the patients by transperineal prostatic TB and systematic biopsy (SB), analyzed the detection rates of PCa and csPCa by TB and SB, and investigated the causes of missed diagnosis of csPCa in TB using the fishbone diagram.Results: The total detection rate of PCa and csPCa by TB combined with SB was 45.7% (298/652), and that of csPCa was 37.4% (244/652), with 38 cases of csPCa missed in TB, including 23 cases of negative TB and 15 cases of low ISUP grade. The causes of missed diagnosis of csPCa by TB included low MRI image quality, PSA density ≤0.15 ng/ml/cm3, target area <10 mm, and PI-RADS 2 score ≤3. The detection rate of csPCa by TB alone was 31.6%, which was increased by 5.8% (P = 0.027) when TB combined with SB.Conclusion: TB combined with SB yields a higher detection rate of csPCa than either used alone. Missed diagnosis of csPCa by TB is closely related to the characteristics of tumor and MR image of the target area.","PeriodicalId":24012,"journal":{"name":"Zhonghua nan ke xue = National journal of andrology","volume":"30 4","pages":"315-320"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142112760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Focal therapy combined with immunotherapy for prostate cancer: Advances in studies]. [前列腺癌的局部治疗与免疫治疗相结合：研究进展]。

Zhonghua nan ke xue = National journal of andrology Pub Date : 2024-04-01

Chuan-Guo Zhang, Wei-Sheng Li, Cong Zheng, Wen-Qiang He

引用次数: 0

[Peripheral blood lymphocyte subsets are associated with the prognosis of prostate cancer]. [外周血淋巴细胞亚群与前列腺癌的预后有关]。

Zhonghua nan ke xue = National journal of andrology Pub Date : 2024-04-01

Fei Mao, Chao Yang, Lu Ji

引用次数: 0

[The role of seminal vesicles in male sexual function]. [精囊在男性性功能中的作用]。

Zhonghua nan ke xue = National journal of andrology Pub Date : 2024-03-01

Bao-Fang Jin, Da-Lin Sun

引用次数: 0

中华男科学杂志最新文献