Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine最新文献

{"title":"[Analysis of the English translation of meridians' path in Miraculous Pivot].","authors":"Ke Cheng, Fan Wu, Meng-hu Guo, Ling Zhao, Hai-ping Deng, Hai-meng Zhang, Li-zhen Wang, Yao Xu, Mactavish James, Xue-yong Shen","doi":"10.3736/jcim20121226","DOIUrl":"https://doi.org/10.3736/jcim20121226","url":null,"abstract":"","PeriodicalId":23993,"journal":{"name":"Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine","volume":"10 12","pages":"1502-6"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31137208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of naringenin on allodynia and hyperalgesia in rats with chronic constriction injury-induced neuropathic pain.","authors":"Shyam Kaulaskar,&nbsp;Pravinkumar Bhutada,&nbsp;Anand Rahigude,&nbsp;Dilpesh Jain,&nbsp;Uday Harle","doi":"10.3736/jcim20121223","DOIUrl":"https://doi.org/10.3736/jcim20121223","url":null,"abstract":"<p><strong>Objective: </strong>To study the analgesic effects of naringenin on chronic constriction injury (CCI) model of neuropathic pain.</p><p><strong>Methods: </strong>After inducing of neuropathic pain by CCI, treatment with 25 and 50 mg/kg of naringenin and 10 mg/kg of pregabalin was given. Rats were evaluated for behavioral tests using Hargreaves apparatus for thermal hyperalgesia, pin prick test for tactile mechanical hyperalgesia and cold water-induced allodynia on days 0, 3, 5, 7, 14 and 21. At the end of study, oxidative stress parameters were measured.</p><p><strong>Results: </strong>Naringenin showed ameliorating action against CCI-induced neuropathic pain in all the tested models. Also, naringenin attenuated the elevated levels of lipid peroxidation and nitric oxide, and restored the level of reduced glutathione.</p><p><strong>Conclusion: </strong>The results of the present investigation suggest that naringenin exhibits analgesic effect in sciatic nerve injury model.</p>","PeriodicalId":23993,"journal":{"name":"Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine","volume":"10 12","pages":"1482-9"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31137205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of electroacupuncture on expression of c-fos protein in the spinal dorsal horn of rats with chronic visceral hyperalgesia.","authors":"De-bo Qi,&nbsp;Wei-min Li","doi":"10.3736/jcim20121224","DOIUrl":"https://doi.org/10.3736/jcim20121224","url":null,"abstract":"<p><strong>Objective: </strong>Acupuncture is widely used in clinics to suppress chronic visceral pain in patients with irritable bowel syndrome (IBS); however, the exact neurobiological mechanisms for its therapeutic effects need further exploration. The aim of this study was to investigate the possible involvement of spinal neurons in the effects of electroacupuncture (EA) in relieving chronic visceral hyperalgesia in a rat model of IBS.</p><p><strong>Methods: </strong>Colon mechanical irritation was applied to male neonatal Sprague-Dawley rats to establish the IBS model. Behavioral test of the abdominal withdraw reflex (AWR) response to colorectal distention stimuli was conducted to judge the degree of colorectal sensitivity. EA at acupoints Zusanli (ST36) and Shangjuxu (ST37) was applied bilaterally in a total of four times every other day, while sham-EA at similar acupoints was done by inserting needles without electrical stimulation. Immunohistochemical methods were used to display the expression of proto-oncogene protein c-fos in the spinal dorsal horn.</p><p><strong>Results: </strong>It was found that AWR scores were significantly increased in the IBS model rats (P<0.01), accompanied with significant increase in the expression of c-fos protein in the superficial laminae (SDH, laminae I and II) and nucleus proprius (NP, laminae III and IV), the neck of the dorsal horn (NECK, laminae V and VI) at lumbosacral (L6-S2) spinal level, and in NECK at thoracolumbar (T13-L2) spinal level, when compared with normal rats (P<0.05). After EA treatment, AWR scores and the expression of c-fos protein in SDH, NP and NECK at similar spinal levels were significantly decreased in the IBS model rats (P<0.05). No such effects on either AWR scores or the expression of c-fos protein were observed in IBS model rats after sham-EA treatment.</p><p><strong>Conclusion: </strong>The abnormally high neuronal excitability in the spinal dorsal horn may be an important reason underlying the visceral hyperalgesia in IBS model rats. EA treatment can relieve the chronic visceral hyperalgesia in IBS rats by suppressing the abnormal neuronal excitability in the spinal dorsal horn.</p>","PeriodicalId":23993,"journal":{"name":"Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine","volume":"10 12","pages":"1490-6"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31137206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of echinacoside on MPP(+)-induced mitochondrial fragmentation, mitophagy and cell apoptosis in SH-SY5Y cells.","authors":"Min Zhu,&nbsp;Mi Zhou,&nbsp;Ying Shi,&nbsp;Wen-wei Li","doi":"10.3736/jcim20121215","DOIUrl":"https://doi.org/10.3736/jcim20121215","url":null,"abstract":"<p><strong>Objective: </strong>To observe the protective effect of echinacoside on mitochondrial fragmentation, mitophagy and cell apoptosis in human neuroblastoma SH-SY5Y cell line exposed to 1-methyl-4-phenylpyridinium (MPP(+)).</p><p><strong>Methods: </strong>The MPP(+) -treated SH-SY5Y cells were divided into control and drug groups. The cell apoptosis was determined by flow cytometry analysis. The alterations in mitochondrial morphology were observed, and the changes in mitochondrial membrane potential and mitophagy were measured.</p><p><strong>Results: </strong>MPP(+) induced severe mitochondrial fragmentation in SH-SY5Y cells. Mitochondrial membrane potential was significantly reduced (P<0.05), which further led to mitophagy and cell apoptosis in SH-SY5Y cells treated with MPP(+) (P<0.05); mitochondrial depolarization, mitophagy and cell apoptosis in echinacoside-treated groups were significantly suppressed (P<0.05), but mitochondrial fragmentation was not affected (P>0.05).</p><p><strong>Conclusion: </strong>MPP(+) can cause severe damage to mitochondrial morphology and the function in SH-SY5Y cells, and echinacoside selectively reverse mitochondrial function and cell apoptosis, yet there is no effect on mitochondrial morphology.</p>","PeriodicalId":23993,"journal":{"name":"Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine","volume":"10 12","pages":"1427-32"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31137328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multifactor designs able to examine the interactions.","authors":"Xiao-lei Bao,&nbsp;Liang-ping Hu","doi":"10.3736/jcim20121206","DOIUrl":"https://doi.org/10.3736/jcim20121206","url":null,"abstract":"<p><p>Multifactor designs that are able to examine the interactions include factorial design, factorial design with a block factor, repeated measurement design; orthogonal design, split-block design, etc. Among all the above design types that are able to examine the interactions, the factorial design is the most commonly used. It is also called the full-factor experimental design, which means that the levels of all the experimental factors involved in the research are completely combined, and k independent repeated experiments are conducted under each experimental condition. The factorial design with a block factor can also examine the influence of a block factor formed by one or more important non experimental factors based on the factorial design. This article introduces the factorial design and the factorial design with a block factor by examples.</p>","PeriodicalId":23993,"journal":{"name":"Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine","volume":"10 12","pages":"1371-4"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31137984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Sisheng Decoction on the immunity and anti-stress function in mice with spleen deficiency syndrome.","authors":"Su-fang Zhang,&nbsp;Chang-quan Ling,&nbsp;Bai Li,&nbsp;Hong-yun Chen,&nbsp;Zhe Chen","doi":"10.3736/jcim20121220","DOIUrl":"https://doi.org/10.3736/jcim20121220","url":null,"abstract":"<p><strong>Objective: </strong>To study the possible mechanism of Sisheng Decoction on spleen deficiency syndrome via the observation of general conditions, immunity and anti-stress function in Dahuang (Radix et Rhizoma Rhei Palmati)-induced mice model.</p><p><strong>Methods: </strong>Mice were randomized and grouped based on the body weight. The establishment of model and the treatment were done simultaneously. Except the mice in normal group, the decoction and the Dahuang powder were separately given in the morning and the afternoon for 14 d. The general condition of the mice, the rectal temperature, the time of burden swimming, the indexes of thymus and spleen and the interleukin-2 (IL-2) concentration in the serum were observed.</p><p><strong>Results: </strong>The group treated with Sisheng Decoction showed better performance than that of the model group, including less stool, strong appetite and fast growth; the medium- and high-dose Sisheng Decoction increased the rectal temperature of mice. There was no statistical difference in the thymus and spleen indexes between the groups treated by Sisheng Decoction and the normal group (P>0.05). The thymus index in groups treated by sisheng Decoction was significantly elevated as compared with the model group (P<0.05). The medium- and high-dose Sisheng Decoction significantly improved the concentration of IL-2 and prolonged the time of burden swimming, as compared to the model group (P<0.05).</p><p><strong>Conclusion: </strong>The medium- and high-dose Sisheng Decoction is good at invigorating spleen and replenishing qi. One of the possible mechanisms may be related with the improvement of the immunity and anti-stress function of the body.</p>","PeriodicalId":23993,"journal":{"name":"Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine","volume":"10 12","pages":"1465-9"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31137202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Qualitative research of the elderly real experience of long-term adherence to Tai Chi exercise].","authors":"Xue Qiao,&nbsp;Yu-fang Hao","doi":"10.3736/jcim20121209","DOIUrl":"https://doi.org/10.3736/jcim20121209","url":null,"abstract":"<p><strong>Objective: </strong>To explore the experience of the process of Tai Chi exercise.</p><p><strong>Methods: </strong>The study was conducted in a local park in Beijing of China where varying numbers of community members gathered to practice Tai Chi every day. Volunteers meeting the inclusion and exclusion criteria were recruited after signed an informed consent form. In-depth interview and the participatory observation were used to know of the real feeling of practicing Tai Chi. The qualitative data obtained from the interviews were analyzed by using Colaizzi seven-step method to find the subjects.</p><p><strong>Results: </strong>Six volunteers having a long-time Tai Chi exercise were recruited in this qualitative study, and their real experience was summarized in the physiological level, psychological level, social level and cultural level. In the physiological level, Tai Chi improves the health and exercise of Tai Chi assists the elderly to develop good living habits. In the psychological level, Tai Chi practice guides the person to inner peace, relieves tension, improves depressive mood state, and makes the elderly regain self worth. In the social level Tai Chi is a good form of community practice. In the cultural level, Tai Chi roots in yin and yang culture and integrates internal and external exercises.</p><p><strong>Conclusion: </strong>Tai Chi is good for body and mind health and the community of practice is very important for practitioners. Tai Chi gains popularity for its benefits to health and psychological adjustments, and its cultural connotation.</p>","PeriodicalId":23993,"journal":{"name":"Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine","volume":"10 12","pages":"1388-93"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31137987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Chinese herbal medicine for side effects of transarterial chemoembolization in liver cancer patients: a systematic review and meta-analysis].","authors":"Xiao-qian Li, Chang-quan Ling","doi":"10.3736/jcim20121204","DOIUrl":"10.3736/jcim20121204","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Primary liver cancer is one of the most commonly seen tumors in clinical practice. Due to the stealthiness and fast progress of liver cancer, only 20% of the patients may have chance to receive operation for radical therapy. Patients seldom get benefit from systematic chemotherapy and as a result, local chemotherapy methods such as transarterial chemoembolization (TACE) have become the mainstay in the treatment of liver cancer. Compared with systematic chemotherapy, TACE produces fewer side effects and most of such side effects are caused by postembolization syndrome manifested as nausea and vomiting, abdominal pain, fever, loss of appetite, etc.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;In this systematic review, effects of Chinese herbal medicine (CHM) in relieving side effects caused by TACE in patients with liver cancer were evaluated and meta-analysis was conducted when possible.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Search strategy: &lt;/strong&gt;Literature search was conducted on August 23rd, 2011. The Cochrane Hepato-Biliary Group Controlled Trials Register, the Cochrane Central Register of Controlled Trials in the Cochrane Library, MEDLINE (Ovid SP), EMBASE (Ovid SP), and Science Citation Index Expanded, China National Knowledge Infrastructure Database, Chongqing VIP Database and Wanfang Data were searched with no time limits.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Inclusion criteria: &lt;/strong&gt;Randomized clinical trials (RCTs) of CHM for TACE-induced side effects in patients with primary liver cancer were eligible for this review, regardless of blinding, language, or publication status.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Data extraction and analysis: &lt;/strong&gt;Search results were screened to select the trials included in this review according to the inclusion criteria, and data were extracted from all the included RCTs by using a self-developed data extraction form. Assessment of risk of bias in included studies was conducted according to the Cochrane Handbook for Systematic Reviews of Intervention (Version 5.0.2): Criteria for judging risk of bias in the \"risk of bias\" assessment tool. Dichotomous data were expressed as risk ratio with its 95% confidence interval (CI). Continuous outcomes were expressed as mean differences with 95% CI. If there was no significant heterogeneity, the results from the fixed-effect model were presented. If the heterogeneity was not substantial, the results from the random-effect model were presented. If the heterogeneity was substantial, a meta-analysis was not performed and a narrative, qualitative summary was performed instead. In the event of substantial clinical, methodological, or statistical heterogeneity, the trial components such as patients, diseases, interventions, comparisons, and outcomes in the included trials were reviewed to decide the reason for heterogeneity.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 47 RCTs were included in this review after screening the search results. Among them, 46 were in Chinese and 1 was in English; 43 were journal ","PeriodicalId":23993,"journal":{"name":"Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine","volume":"10 12","pages":"1341-62"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31137983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of propolis on lingual mucosa response of hamsters submitted to experimental carcinogenesis.","authors":"Lopes-Rocha Ricardo,&nbsp;Barroso Poliana Ribeiro,&nbsp;Santos Alexandre Soares,&nbsp;Lima Nádia Lages,&nbsp;Ferreira Fernanda Oliveira,&nbsp;Verli Flaviana Dornela","doi":"10.3736/jcim20121217","DOIUrl":"https://doi.org/10.3736/jcim20121217","url":null,"abstract":"<p><strong>Objective: </strong>To assess the tissue reaction of the lingual mucosa in hamsters submitted to daily, alternating, topical applications of 9,10-dimethyl-1,2-benzanthracene (DMBA) and a commercial brand of an ethanol propolis extract (EPE).</p><p><strong>Methods: </strong>A total of 60 hamsters were divided into three groups with two experimental periods (13 and 20 weeks). The lateral edge of the tongue was submitted to daily, alternating, topical applications of 0.5% DMBA and 30% EPE (EPE group, n=20), 0.5% of DMBA and aqueous propolis extract (APE group, n=20) and 0.5% of DMBA and saline solution (DMBA group, n=20). The occurrence of clinical and histological alterations was analyzed, along with the measurement of the area and volume of the clinical alterations, the determination of structural and cytological alterations of the squamous epithelial tissue with atypias and the measurement of the histological area of squamous cell carcinomas.</p><p><strong>Results: </strong>There were no significant differences among groups regarding any of the variables analyzed in the two evaluation periods. At week 13, a single squamous cell carcinoma occurred in the EPE group. At week 20, the greatest occurrence of squamous cell carcinoma was also in the EPE group.</p><p><strong>Conclusion: </strong>The mechanism of EPE (30% alcohol content) affecting the onset of tissue reaction and the promotion of carcinogenesis has not been clarified yet.</p>","PeriodicalId":23993,"journal":{"name":"Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine","volume":"10 12","pages":"1443-50"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31137330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A complexity analysis of Chinese herbal property theory: the multiple expressions of herbal property].","authors":"Rui Jin,&nbsp;Bing Zhang","doi":"10.3736/jcim20121201","DOIUrl":"https://doi.org/10.3736/jcim20121201","url":null,"abstract":"<p><p>Chinese herbal property is the highly summarized concept of herbal nature and pharmaceutical effect, which reflect the characteristics of herbal actions on human body. These herbal actions, also interpreted as presenting the information about pharmaceutical effect contained in herbal property on the biological carrier, are defined as herbal property expressions. However, the biological expression of herbal property is believed to possess complex features for the involved complexity of Chinese medicine and organism. Firstly, there are multiple factors which could influence the expression results of herbal property such as the growth environment, harvest season and preparing methods of medicinal herbs, and physique and syndrome of body. Secondly, there are multiple biological approaches and biochemical indicators for the expression of the same property. This paper elaborated these complexities for further understanding of herbal property. The individuality of herbs and expression factors should be well analyzed in the related studies.</p>","PeriodicalId":23993,"journal":{"name":"Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine","volume":"10 12","pages":"1321-7"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31138047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}