{"title":"Cold snare polypectomy: A closer look at the efficacy and limitations for polyps 10-20 mm in size.","authors":"Louis A Chaptini, Sarah Jalloul, Karam Karam","doi":"10.4253/wjge.v16.i8.445","DOIUrl":"10.4253/wjge.v16.i8.445","url":null,"abstract":"<p><p>Current guidelines recommend cold snare polypectomy for polyps less than 10 mm in size. Conversely, endoscopic mucosal resection is still the preferred technique for larger polyps. Concerns regarding cold snare polypectomy for larger polyps revolve around the difficulty in conducting <i>en-bloc</i> resection (resulting in piecemeal removal), and the potential for local residual polyp tissue and a high rate of recurrence. On the other hand, cold snare technique has the advantages of shortening procedure time, reducing delayed bleeding risks and lowering cost of treatment. Numerous ongoing and recent studies are focused on evaluating the risks and benefits of this technique for polyps larger than 10 mm, with the goal of providing clear guidelines in the near future. The aim of this editorial is to provide our readers with an overview regarding this subject and the latest developments surrounding it.</p>","PeriodicalId":23953,"journal":{"name":"World Journal of Gastrointestinal Endoscopy","volume":"16 8","pages":"445-450"},"PeriodicalIF":1.4,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Filipe Vilas-Boas, Giacomo Emanuele Maria Rizzo, Charles De Ponthaud, Stuart Robinson, Sebastien Gaujoux, Gabriele Capurso, Giuseppe Vanella, Bahadır Bozkırlı
{"title":"Unveiling hidden outcomes in malignant gastric outlet obstruction research - insights from a \"Pancreas 2000\" review.","authors":"Filipe Vilas-Boas, Giacomo Emanuele Maria Rizzo, Charles De Ponthaud, Stuart Robinson, Sebastien Gaujoux, Gabriele Capurso, Giuseppe Vanella, Bahadır Bozkırlı","doi":"10.4253/wjge.v16.i8.451","DOIUrl":"10.4253/wjge.v16.i8.451","url":null,"abstract":"<p><p>Malignant gastric outlet obstruction (mGOO) is a major condition affecting patients with periampullary tumors, including pancreatic cancer. The current treatment options include surgical gastroenterostomy, endoscopic stenting and more recently EUS-guided gastroenterostomy. Most studies comparing the outcomes of the three procedures focus on technical success, clinical success and safety. Several \"occult\" outcomes relevant to the patient's viewpoints and perspective may ultimately impact on cancer-related and overall survival, such as body mass composition, nutritional biomarkers, chemotherapy tolerance and patient-reported quality of life. The aim of this review is to provide an overview of potential key outcomes that should be explored in future comparative research around mGOO treatment options.</p>","PeriodicalId":23953,"journal":{"name":"World Journal of Gastrointestinal Endoscopy","volume":"16 8","pages":"451-461"},"PeriodicalIF":1.4,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heterotopic mesenteric ossification caused by trauma: A case report.","authors":"Bi-Fang Zhang, Jiang Liu, Shuai Zhang, Ling Chen, Jia-Zheng Lu, Ming-Qing Zhang","doi":"10.4253/wjge.v16.i8.494","DOIUrl":"10.4253/wjge.v16.i8.494","url":null,"abstract":"<p><strong>Background: </strong>Heterotopic mesenteric ossification (HMO) is a clinically rare condition characterized by the formation of bone tissue in the mesentery. The worldwide reporting of such cases is limited to just over 70 instances in the medical literature. The etiology of HMO remains unclear, but the disease is possibly induced by mechanical trauma, ischemia, or intra-left lower quadrant abdominal infection, leading to the differentiation of mesenchymal stem cells into osteoblasts. Here, we present a rare case of HMO that occurred in a 34-year-old male, who presented with left lower quadrant abdominal pain.</p><p><strong>Case summary: </strong>We report the case of a 34-year-old male patient who presented with left lower abdominal pain following trauma to the left lower abdomen. He subsequently underwent surgical treatment, and the postoperative pathological diagnosis was HMO.</p><p><strong>Conclusion: </strong>We believe that although there is limited literature and research on HMO, when patients with a history of trauma or surgery to the left lower abdomen present with corresponding imaging findings, clinicians should be vigilant in distinguishing this condition and promptly selecting appropriate diagnostic and therapeutic interventions.</p>","PeriodicalId":23953,"journal":{"name":"World Journal of Gastrointestinal Endoscopy","volume":"16 8","pages":"494-499"},"PeriodicalIF":1.4,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142001700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giulio Calabrese, Guido Manfredi, Marcello F Maida, Francesco V Mandarino, Endrit Shahini, Francesco Pugliese, Paolo Cecinato, Liboria Laterza, Emanuele Sinagra, Sandro Sferrazza
{"title":"Challenges and advancing strategies of endoscopic submucosal dissection for early gastric cancer: The puzzle of eCura C1.","authors":"Giulio Calabrese, Guido Manfredi, Marcello F Maida, Francesco V Mandarino, Endrit Shahini, Francesco Pugliese, Paolo Cecinato, Liboria Laterza, Emanuele Sinagra, Sandro Sferrazza","doi":"10.4253/wjge.v16.i8.439","DOIUrl":"10.4253/wjge.v16.i8.439","url":null,"abstract":"<p><p>In this editorial, we explore the challenges of managing noncurative resections in early gastric cancer after endoscopic submucosal dissection (ESD), starting from the consideration recently made by Zhu <i>et al</i>. Specifically, we evaluate the management of eCura C1 lesions, where decisions regarding further interventions are pivotal yet contentious. Collaboration among endoscopists, surgeons, and pathologists is underscored to refine risk assessment and personalize therapeutic management. Recent advancements in ESD techniques and interdisciplinary collaboration offer opportunities for outcome optimization in managing eCura C1 lesions. Moreover, despite needing further clinical validation, molecular biomarkers have emerged as promising tools for enhancing prognostication. This manuscript highlights the ongoing research attempts to define treatment paradigms effectively and evaluates the potential of emerging options, ultimately aiming to improve patient care and outcomes in this complex clinical scenario.</p>","PeriodicalId":23953,"journal":{"name":"World Journal of Gastrointestinal Endoscopy","volume":"16 8","pages":"439-444"},"PeriodicalIF":1.4,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ya-Jie Teng, Ying-Xue Yang, Jing-Jing Yang, Qiu-Yan Lu, Jia-Yi Shi, Jian-Hao Xu, Jie Bao, Qing-Hua Wang
{"title":"Retraction note to: Association between triglyceride-glucose index and colorectal polyps: A retrospective cross-sectional study.","authors":"Ya-Jie Teng, Ying-Xue Yang, Jing-Jing Yang, Qiu-Yan Lu, Jia-Yi Shi, Jian-Hao Xu, Jie Bao, Qing-Hua Wang","doi":"10.4253/wjge.v16.i8.500","DOIUrl":"10.4253/wjge.v16.i8.500","url":null,"abstract":"<p><p>[This retracts the article on p. 55 in vol. 16, PMID: 38464818.].</p>","PeriodicalId":23953,"journal":{"name":"World Journal of Gastrointestinal Endoscopy","volume":"16 8","pages":"500-501"},"PeriodicalIF":1.4,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325869/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142001701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sebhatleab T Mulate, Abdulsemed M Nur, Abel T Tasamma, Rodas T Annose, Esmael M Dawud, Kinfe W Ekubazgi, Hailemichael D Mekonnen, Hidaya Y Mohammed, Meron B Hailemeskel, Shimelis A Yimer
{"title":"Colonic schistosomiasis mimicking cancer, polyp, and inflammatory bowel disease: Five case reports and review of literature.","authors":"Sebhatleab T Mulate, Abdulsemed M Nur, Abel T Tasamma, Rodas T Annose, Esmael M Dawud, Kinfe W Ekubazgi, Hailemichael D Mekonnen, Hidaya Y Mohammed, Meron B Hailemeskel, Shimelis A Yimer","doi":"10.4253/wjge.v16.i8.472","DOIUrl":"10.4253/wjge.v16.i8.472","url":null,"abstract":"<p><strong>Background: </strong>Schistosomiasis, officially named as a neglected tropical disease by The World Health Organization, is a serious parasitic disease caused by trematode flukes of the genus <i>Schistosoma</i>. It is a common infectious disease, endemic in more than 78 countries. The disease can involve various organs and poses far-reaching public health challenges.</p><p><strong>Case summary: </strong>Here, we present a series of five patients with variable presentations: an asymptomatic patient who was diagnosed with colonic schistosomiasis upon screening colonoscopy; 2 patients with clinical suspicion of colonic cancer; and 2 patients with a clinical diagnosis of inflammatory bowel disease. All patients were subsequently confirmed to have colonic schistosomiasis after colonoscopy and histopathologic examination. The clinical manifestations, colonoscopy features and histologic findings of the patients are described. Most of the patients showed significant clinical improvement following administration of oral praziquantel.</p><p><strong>Conclusion: </strong>Intestinal schistosomiasis can present with features mimicking other gastrointestinal conditions. This disease should be a diagnostic consideration in patients who live in or have traveled to endemic areas.</p>","PeriodicalId":23953,"journal":{"name":"World Journal of Gastrointestinal Endoscopy","volume":"16 8","pages":"472-482"},"PeriodicalIF":1.4,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325876/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sergey M Kotelevets, Sergey A Chekh, Sergey Z Chukov
{"title":"Effectiveness of serological markers of gastric mucosal atrophy in the gastric precancer screening and in cancer prevention.","authors":"Sergey M Kotelevets, Sergey A Chekh, Sergey Z Chukov","doi":"10.4253/wjge.v16.i8.462","DOIUrl":"10.4253/wjge.v16.i8.462","url":null,"abstract":"<p><strong>Background: </strong>New markers are needed to improve the effectiveness of serological screening for atrophic gastritis.</p><p><strong>Aim: </strong>To develop a cost-effective method for serological screening of atrophic gastritis with a high level of sensitivity.</p><p><strong>Methods: </strong>Of the 169 patients with atrophic gastritis, selected by the visual endoscopic Kimura-Takemoto method, 165 showed histological mucosal atrophy using the updated Kimura-Takemoto method. All 169 patients were examined for postprandial levels of gastrin-17 (G17) and pepsinogen-1 (PG1) using GastroPanel<sup>®</sup> (Biohit Plc, Helsinki, Finland).</p><p><strong>Results: </strong>We used the histological standard of five biopsies of the gastric mucosa, in accordance with the Kimura-Takemoto classification system to assess the sensitivity of G17 in detecting gastric mucosal atrophy. We also compared the morpho-functional relationships between the detected histological degree of gastric mucosal atrophy and the serological levels of G17 and PG1, as the markers of atrophic gastritis. The sensitivity of postprandial G17 was 62.2% for serological levels of G17 (range: 0-4 pmol/L) and 100% for serological G17 (range: 0-10 pmol/L) for the detection of monofocal severe atrophic gastritis. No strong correlation was found between the levels of PG1 and degree of histological atrophy determined by the Kimura-Takemoto classification system to identify the severity of mucosal atrophy of the gastric corpus. In the presented clinical case of a 63-year-old man with multifocal atrophic gastritis, there is a pronounced positive long-term dynamics of the serological marker of atrophy - postprandial G17, after five months of rennet replacement therapy.</p><p><strong>Conclusion: </strong>Serological screening of multifocal atrophic gastritis by assessment of postprandial G17 is a cost-effective method with high sensitivity. Postprandial G17 is an earlier marker of regression of atrophic gastritis than a morphological examination of a gastric biopsy in accordance with the Sydney system. Therefore, postprandial G17 is recommended for dynamic monitoring of atrophic gastritis after treatment.</p>","PeriodicalId":23953,"journal":{"name":"World Journal of Gastrointestinal Endoscopy","volume":"16 8","pages":"462-471"},"PeriodicalIF":1.4,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endoscopic ultrasound-guided treatment of isolated gastric varices entwined with arteries: A case report.","authors":"Hong-Ying Zhang, Chen-Cong He, Ding-Fu Zhong","doi":"10.4253/wjge.v16.i8.489","DOIUrl":"10.4253/wjge.v16.i8.489","url":null,"abstract":"<p><strong>Background: </strong>Interventional endoscopic ultrasound is clinically used for the treatment of isolated gastric varices (IGVs) owing to its precise visualization.</p><p><strong>Case summary: </strong>A 39-year-old man was diagnosed with a large IGV during a routine physical examination. Endoscopic ultrasonography showed gastric varices entwined with an artery, which greatly increased the difficulty of treatment. We successfully treated the patient with endoscopic ultrasonography-guided coil embolization combined with cyanoacrylate injection.</p><p><strong>Conclusion: </strong>Endoscopic ultrasonography-guided coil embolization combined with cyanoacrylate injection was safe and effective for the treatment of an IGV entwined with an artery.</p>","PeriodicalId":23953,"journal":{"name":"World Journal of Gastrointestinal Endoscopy","volume":"16 8","pages":"489-493"},"PeriodicalIF":1.4,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325873/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142001699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Enrico Fiori, Antonietta Lamazza, Daniele Crocetti, Antonio V Sterpetti
{"title":"Editorial article to: Animal experimental study on magnetic anchor technique-assisted endoscopic submucosal dissection of early gastric cancer.","authors":"Enrico Fiori, Antonietta Lamazza, Daniele Crocetti, Antonio V Sterpetti","doi":"10.4253/wjge.v16.i2.51","DOIUrl":"10.4253/wjge.v16.i2.51","url":null,"abstract":"<p><p>In this editorial we comment on the article published in the recent issue of the <i>World Journal of Gastrointestinal Endoscopy</i> 2023; 15 (11): 634-680. Gastric cancer (GC) remains the fifth most common malignancy and the fourth leading cause of cancer-related death worldwide. The overall prevalence of GC has declined, although that of proximal GC has increased over time. Thus, a significant proportion of GC cases and deaths can be avoided if preventive interventions are taken. Early GC (EGC) is defined as GC confined to the mucosa or submucosa. Endoscopic resection is considered the most appropriate treatment for precancerous gastrointestinal lesions improving patient quality of life, with reduced rates of complications, shorter hospitalization period, and lower costs when compared to surgical resection. Endoscopic mucosal resection (EMR) and endoscopic sub-mucosal dissection (ESD) are representative endoscopic treatments for EGC and precancerous gastric lesions. Standard EMR implies injection of a saline solution into the sub-mucosal space, followed by excision of the lesion using a snare. Complete resection rates vary depending on the size and severity of the lesion. When using conventional EMR methods for lesions less than 1 cm in size, the complete resection rate is approximately 60%, whereas for lesions larger than 2 cm, the complete resection rate is low (20%-30%). ESD can be used to remove tumors exceeding 2 cm in diameter and lesions associated with ulcers or submucosal fibrosis. Compared with EMR, ESD has higher en bloc resection rates (90.2% <i>vs</i> 51.7%), higher complete resection rates (82.1 <i>vs</i> 42.2%), and lower recurrence rates (0.65% <i>vs</i> 6.05%). Thus, innovative techniques have been introduced.</p>","PeriodicalId":23953,"journal":{"name":"World Journal of Gastrointestinal Endoscopy","volume":"16 2","pages":"51-54"},"PeriodicalIF":2.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10921155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140094741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coca-Cola consumption <i>vs</i> fragmentation in the management of patients with phytobezoars: A prospective randomized controlled trial.","authors":"Fu-Guo Liu, De-Feng Meng, Xia Shen, Dan Meng, Ying Liu, Ling-Yun Zhang","doi":"10.4253/wjge.v16.i2.83","DOIUrl":"10.4253/wjge.v16.i2.83","url":null,"abstract":"<p><strong>Background: </strong>Gastric phytobezoars (GPBs) are very common in northern China. Combined therapy involving carbonated beverage consumption and endoscopic lithotripsy has been shown to be effective and safe. Existing studies on this subject are often case reports highlighting the successful dissolution of phytobezoars through Coca-Cola consumption. Consequently, large-scale prospective investigations in this domain remain scarce. Therefore, we conducted a randomized controlled trial to examine the effects of Coca-Cola consumption on GPBs.</p><p><strong>Aim: </strong>To evaluate the impact of Coca-Cola on GPBs, including the dissolution rate, medical expenses, ulcer rate, and operation time.</p><p><strong>Methods: </strong>A total of 160 consecutive patients diagnosed with GPBs were allocated into two groups (a control group and an intervention group) through computer-generated randomization. Patients in the intervention group received a Coca-Cola-based regimen (Coca-Cola 2000-4000 mL per day for 7 d), while those in the control group underwent emergency fragmentation.</p><p><strong>Results: </strong>Complete dissolution of GPBs was achieved in 100% of the patients in the intervention group. The disparity in expenses between the control group and intervention group (<i>t</i> = 25.791, <i>P</i> = 0.000) was statistically significant, and the difference in gastric ulcer occurrence between the control group and intervention group (<i>χ</i><sup>2</sup> = 6.181, <i>P</i> = 0.013) was also statistically significant.</p><p><strong>Conclusion: </strong>Timely ingestion of Coca-Cola yields significant benefits, including a complete dissolution rate of 100%, a low incidence of gastric ulcers, no need for fragmentation and reduced expenses.</p>","PeriodicalId":23953,"journal":{"name":"World Journal of Gastrointestinal Endoscopy","volume":"16 2","pages":"83-90"},"PeriodicalIF":2.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10921151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140094739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}