A. Porta, G. D'addio, G. Pinna, R. Maestri, T. Gnecchi-Ruscone, R. Furlan, N. Montano, S. Guzzetti, A. Malliani
{"title":"Symbolic analysis of 24h holter heart period variability series: comparison between normal and heart failure patients","authors":"A. Porta, G. D'addio, G. Pinna, R. Maestri, T. Gnecchi-Ruscone, R. Furlan, N. Montano, S. Guzzetti, A. Malliani","doi":"10.1109/CIC.2005.1588166","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588166","url":null,"abstract":"This study proposes an application of symbolic analysis to beat-to-beat heart rate variability data derived from 24 h Holter recordings both in healthy and heart failure populations. Heart rate series are transformed in a sequence of six symbols via a uniform quantization procedure. Symbols are grouped in patterns lasting three cardiac cycles and these patterns are grouped in few (four) families without any loss. The rate of occurrence of these families are found useful to distinguish two physiological conditions characterised by a different status of the autonomic nervous system (i.e. day-time and night-time) in healthy subjects and to discriminate between healthy and pathological populations. Indexes derived from symbolic analysis deserve to be added to traditional time and frequency domain parameters in standard analysis of heart rate variability obtained from 24 h Holter recordings and tested over larger databases","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133448928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new ventricular fibrillation detection algorithm for automated external defibrillators","authors":"A. Amann, R. Tratnig, K. Unterkofler","doi":"10.1109/CIC.2005.1588162","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588162","url":null,"abstract":"A pivotal component in AEDs is the detection of ventricular fibrillation by means of appropriate detection algorithms. In scientific literature there exists a wide variety of methods and ideas for handling this task. These algorithms should have a high detection quality, be easily implementable, and work in real time in an AED. Testing of these algorithms should be done by using a large amount of annotated data under equal conditions. For our investigation we simulated a continuous analysis by selecting the data in steps of one second without any preselection. We used the BIH-MIT arrhythmia, the CU, and the AHA database. For a new ventricular fibrillation detection algorithm we calculated the sensitivity, specificity, and the area under its receiver operating characteristic curve (ROC) and compared these values with the results from an earlier investigation of several different ventricular fibrillation detection algorithms. This new algorithm is based on the Hilbert transform and outperforms all other investigated algorithms","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"262 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133531453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An original method to quantify mitochondria movement in cultured cardiomyocytes","authors":"S. Pelloux, C. Ojeda, Y. Tourneur","doi":"10.1109/CIC.2005.1588229","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588229","url":null,"abstract":"We studied in confocal microscopy non-beating cells from the HL-1 cardiac cell line. Using a fluorescent dye, mitochondria appeared as a dense tubular network, in permanent fusion, fission and displacement. To quantify these movements in response to pharmacological stimuli, we needed a method only based on their position. Time-lapse recording was performed in physiological medium. Every image was first converted into binary images by ultimate erosion or skeletonization. Then a distance map was created by attributing to every point a grey level equal to the distance from the skeleton. In a third step, the following binary image was laid over the distance image, by pixel to pixel multiplication. The pixel value below the binary objects indicated the distance ran between the two images. The method is fast and accurate, and can be scaled in absolute values. The average velocity lies in the range obtained by other methods","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133950232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Tormos, J. Millet, F. Chorro, L. Such, J. Cánoves, L. Mainar, E. Blasco, I. Trapero
{"title":"Changes in ventricular refractoriness and conduction velocity induced by local hypothermia and hyperthermia","authors":"A. Tormos, J. Millet, F. Chorro, L. Such, J. Cánoves, L. Mainar, E. Blasco, I. Trapero","doi":"10.1109/CIC.2005.1588155","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588155","url":null,"abstract":"VF pattern is related to the electrophysiological parameters of the myocardium. Although the influence of global temperature on these parameters is known, the effects of its regional variations have not been sufficiently studied. We examined the effects of local hypothermia and hyperthermia on refractoriness and conduction velocity (VC), during constant pacing at cycle lengths of 250 ms. In an experimental model (rabbit isolated heart) we used a new method to perform epicardial cooling and heating on the registered surface. The results show that local variations of temperature generate heterogeneity in the electrophysiological properties of the heart. Hypothermia prolongs refractoriness and decreases VC, in a reversible manner. Hyperthermia (42degC) has the opposite effects. The wavelength of the cardiac impulse is not altered because of the opposite and proportional actions on functional refractory period and VC","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132277771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Linear prediction modeling for evaluating abnormal intra QRS potentials in the high-resolution electrocardiogram","authors":"C. Lin","doi":"10.1109/CIC.2005.1588140","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588140","url":null,"abstract":"The purpose of this paper is to obtain abnormal intra-QRS potentials (AIQP) from a signal-averaged electrocardiogram (SAECG) have been proposed to indicate the risk of ventricular arrhythmias. However, the major limitation of current autoregressive moving average modeling is that the model order depends on the database. This study presented a new method based on the linear prediction modeling to improve the limits in AIQP analysis. A total of 154 normal Taiwanese (N), 94 ventricular premature contraction (VPC) patients and 26 sustained ventricular tachycardia (VT) patients were recruited. The AIQP were extracted from the modeling residual of a linear prediction model. From the analyses of all modeling residual curves (modeling residual versus model order), the optimal model order is six. The AIQP was quantified by the root-mean-square value of the modeling residual within QRS interval. The AIQP of VT patients were significantly greater than those of non-VT groups (normal and VPC groups) (p<0.05). No significant differences appeared between normal and VPC groups. A linear combination of AIQP in leads X, Y and Z and three standardized time-domain SAECG parameters provide the best diagnostic performance (specificity 85.9%, sensitivity 88.5% and predictive accuracy 86.2%). It is concluded that the AIQP can be extracted by the linear prediction modeling to evaluate the risk of ventricular arrhythmias, which can enhance the diagnostic performance of time-domain SAECG. And, the linear prediction modeling improves the clinical feasibility of AIQP analysis","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134299258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Hostetler, J. Xue, B. Young, W. Kaiser, M. Findeis, D. Gutterman
{"title":"Detect short run of TWA event with time-domain algorithm","authors":"B. Hostetler, J. Xue, B. Young, W. Kaiser, M. Findeis, D. Gutterman","doi":"10.1109/CIC.2005.1588142","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588142","url":null,"abstract":"T-wave alternans (TWA) has been associated with ventricular arrhythmias, and some of them are non-stationary, short-episode events (less than 128 beats). A specific time-domain algorithm for isolating T-wave alternans from ECG signals during exercise was developed. The purpose of this study was to test the hypothesis that the time-domain TWA algorithm can accurately quantify exercise TWA patterns, either long or short in duration, and evaluate the TWA measurement difference between time-domain and frequency-domain TWA methods","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115677080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. J. Bruns, F. Braunschweig, D. Ersgård, M. Stalberg, P. Reiters, P. Grandjean, K. Hilpisch, C. Linde, M. Hill
{"title":"Opportunities for optimization of biventricular pacing using an implanted hemodynamic monitor","authors":"H. J. Bruns, F. Braunschweig, D. Ersgård, M. Stalberg, P. Reiters, P. Grandjean, K. Hilpisch, C. Linde, M. Hill","doi":"10.1109/CIC.2005.1588049","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588049","url":null,"abstract":"Optimization of pacing parameters such as AV delay is important in heart failure (HF) patients treated with cardiac resynchronization therapy (CRT). We hypothesized, that an implantable hemodynamic monitor (IHM) might be helpful in identifying the optimal AV-delay. 10 patients with HF, successfully treated by CRT were also implanted with an IHM that continuously records heart rate, activity, RV pressures and an estimation of the pulmonary artery diastolic pressure (ePAD). First, AV delays were optimized by echo, then different AV-delays (50-190 ms) were randomly programmed using steps of 20 ms. Using the IHM, a U-shaped curve was obtained with an optimal AV delay slightly longer as compared with echo. Shortening the AV interval resulted in increased ePAD values. In future, CRT optimization may be guided by hemodynamic sensors recording basic cardiovascular measures during daily activities of living","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117163930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Savitzky-Golay least-squares polynomial filters in ECG signal processing","authors":"S. Hargittai","doi":"10.1109/CIC.2005.1588216","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588216","url":null,"abstract":"The Savitzky-Golay(SG) filters are widely used for smoothing and differentiation in many fields namely in elastography, EEG and magnetocardiogram signal processing and mainly in absorption spectroscopy. Despite their exceptional features they were rarely used so far in the ECG signal processing. The aim of this paper is the investigation of their properties in detail from the ECG signal processing aspect. There were considered smoothing and differentiation filters approximating polynomials of zero to fourth order with 3-25-point lengths. The filtering effect and the retaining of small details of signal are opposite requirements and depend on the length and the order of applied polynomial. Taking into consideration 500 Hz sampling rate, size of smallest relevant ECG and requirements of approximating peaks and inflections in ECG signal processing, the best choice of use is the quartic smoothing and differentiation filters with 17-point length","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115406775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Neyran, S. Carme, M. Wiart, M. Robini, E. Soulas
{"title":"Mapping myocardial perfusion with an intravascular MR contrast agent, a robust estimation by a spatially constrained approach","authors":"B. Neyran, S. Carme, M. Wiart, M. Robini, E. Soulas","doi":"10.1109/CIC.2005.1588123","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588123","url":null,"abstract":"Evaluation of quantitative parameters such as regional myocardial blood flow (rMBF), blood volume (rMBV), and mean transit time (rMTT) by MRI is gaining acceptance for clinical applications, but still lacks robust post-processing methods for map generation. Pixel by pixel analysis leads to high variance of the estimates and variance reduction by posterior spatial averaging does not produce satisfactory results. We propose a parametric estimation technique that smoothes the variance of the estimates within parametric homogeneous regions while preserving discontinuities (in the sense that smoothing is not performed across regions with different parametric contents). Our approach lies within the Bayesian framework. It is based on local autoregressive moving average (ARMA) estimation, constrained by an edge-preserving smoothness prior. The prior stems from Markov random fields (MRF) modeling and involves non-quadratic potential functions. The output of the resulting algorithm is a regularized rMBF map. The method is validated on synthetic MR kinetics and tested on first-pass T1 images of an isolated pig heart using an intravascular contrast agent. Comparison of our results with pixel by pixel estimates clearly demonstrate the ability of the proposed approach to improve parametric estimation in terms of variance reduction and discontinuity preservation","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124793700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Ecabert, J. Peters, C. Lorenz, J. von Berg, M. Vembar, K. Subramanyan, G. Lavi, J. Weese
{"title":"Towards automatic full heart segmentation in computed-tomography images","authors":"O. Ecabert, J. Peters, C. Lorenz, J. von Berg, M. Vembar, K. Subramanyan, G. Lavi, J. Weese","doi":"10.1109/CIC.2005.1588077","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588077","url":null,"abstract":"We present a robust, fast and fully automatic approach enabling the segmentation of the main anatomical structures of the heart in CT images. The proposed method is based on the adaptation of a 3D triangulated mesh to new unknown images exploiting simultaneously knowledge of organ shape and typical gray level appearance in images, both learned from a training database made of 28 data sets. The described approach was tested on more than 50 volume images at different cardiac phases. Visual inspection by experts reveals that the proposed method is overall robust and succeeds in segmenting the heart up to minor interactive local corrections","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123639177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}