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Zeitschrift fur Immunitatsforschung. Immunobiology最新文献

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Requirement for interactions between two subpopulations of T cells for helper cell induction in vitro. 体外辅助细胞诱导需要两个T细胞亚群之间的相互作用。
Zeitschrift fur Immunitatsforschung. Immunobiology Pub Date : 1977-09-01
M Feldmann, P Erb
{"title":"Requirement for interactions between two subpopulations of T cells for helper cell induction in vitro.","authors":"M Feldmann,&nbsp;P Erb","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The evidence for the interaction of 2 subpopulations of T cells, short-lived cells sensitive to adult thymectomy (T1 cells), and long-lived recirculating cells, sensitive to the action of antilymphocyte serum (T2 cells) in the induction of helper cells is presented. This T-T interaction occurred across a cell-impermeable nucleopore membrane, indicating that it did not depend on cell contact, but was mediated by subcellular factors. There was no genetic restriction on this T-T interaction, if it was performed across a nucleopore membrane. The implications of these results on our concepts of the mechanism of help are discussed.</p>","PeriodicalId":23935,"journal":{"name":"Zeitschrift fur Immunitatsforschung. Immunobiology","volume":"153 3","pages":"217-25"},"PeriodicalIF":0.0,"publicationDate":"1977-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11517619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of specific IgE and IgG serum antibodies during immunotherapy in hay fever patients by RAST. 用RAST测定花粉热患者免疫治疗期间特异性IgE和IgG血清抗体。
Zeitschrift fur Immunitatsforschung. Immunobiology Pub Date : 1977-09-01
F Osterhage, M Wippler, J R Kalden, H Deicher
{"title":"Determination of specific IgE and IgG serum antibodies during immunotherapy in hay fever patients by RAST.","authors":"F Osterhage,&nbsp;M Wippler,&nbsp;J R Kalden,&nbsp;H Deicher","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A solid phase radio-immunoassay, based on the commercially available antigen preparations on paper discs supplied with the radio-allergosorbent test (Phadebas RAST, Pharmacia) for semi-quantitative determination of specific IgE has been applied to the demonstration of allergen-specific antibodies of the IgG class in sera of hay fever patients. A significant rise of specific IgG antibody has been observed regularly as a result of successful immunotherapy. The rise of such \"blocking antibodies\" occurred within 3 months after commencement of immunotherapy (IT), well before nasal provocation tests became negative in the patients. No significant decrease of specific IgE antibodies was observed over the one year observation period. While these data confirm earlier results by other groups concerning the appearance of blocking antibodies of IgG class as a result of IT, thus providing additional evidence for its mechanism, they also offer a convenient serological method for monitoring the results of IT.</p>","PeriodicalId":23935,"journal":{"name":"Zeitschrift fur Immunitatsforschung. Immunobiology","volume":"153 3","pages":"189-203"},"PeriodicalIF":0.0,"publicationDate":"1977-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12112874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sensitization of rat T cells to syngeneic tumor cultures by cocultivation in diffusion chambers. 扩散室共培养大鼠T细胞对同源肿瘤的致敏作用。
Zeitschrift fur Immunitatsforschung. Immunobiology Pub Date : 1977-09-01
S Cornain, S Becker, E Klein
{"title":"Sensitization of rat T cells to syngeneic tumor cultures by cocultivation in diffusion chambers.","authors":"S Cornain,&nbsp;S Becker,&nbsp;E Klein","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Total population and T cell enriched fractions of rat spleen were cultivated in diffusion chambers implanted intraperitoneally to mice and rats. 10-16% of the input cells were recovered after 5 days. When the chambers were carried in the xenogeneic environment activation occurred as indicated by blastogenesis and non-discriminative cytotoxicity. Specific activation of the T population was induced by mixed lymphocyte-tumor culture in chambers implanted in rats. The presence of tumor cells induced blastogenesis, elevation of the proportion of Fc receptor positive cells and generated cytotoxic cells to the sensitizer tumor. The precursor of cytotoxic cells did not have Fc or C3 receptors since nylon wool colum passed fractions depleted from these cells by elimination of EA- or EAC-rosettes were also activated.</p>","PeriodicalId":23935,"journal":{"name":"Zeitschrift fur Immunitatsforschung. Immunobiology","volume":"153 3","pages":"248-64"},"PeriodicalIF":0.0,"publicationDate":"1977-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11362986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early kinetics of B cell memory and the influence of T cells on the expression in vitro. B细胞记忆早期动力学及T细胞对体外表达的影响。
Zeitschrift fur Immunitatsforschung. Immunobiology Pub Date : 1977-09-01
G Kraal, D Boden
{"title":"Early kinetics of B cell memory and the influence of T cells on the expression in vitro.","authors":"G Kraal,&nbsp;D Boden","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To study the early kinetics of B cell memory to sheep erythrocytes mouse spleen cells were cultured after short priming times in vivo. The influence of T cells on the expression of memory in vitro was investigated by treatment with anti-theta serum. Within 48 hours of in vivo priming part of the B cell population can differentiate into cells capable of IgG production after secondary antigen contact in vitro without the help of T cells. The presence of antigen was required for the in vitro development.</p>","PeriodicalId":23935,"journal":{"name":"Zeitschrift fur Immunitatsforschung. Immunobiology","volume":"153 3","pages":"226-35"},"PeriodicalIF":0.0,"publicationDate":"1977-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11517620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cellular immune reactions in patients with bronchogenic carcinoma before and after radio-, chemo- and immunotherapy. 支气管源性癌患者放射、化疗和免疫治疗前后的细胞免疫反应。
Zeitschrift fur Immunitatsforschung. Immunobiology Pub Date : 1977-09-01
C Gropp, K Havemann
{"title":"Cellular immune reactions in patients with bronchogenic carcinoma before and after radio-, chemo- and immunotherapy.","authors":"C Gropp,&nbsp;K Havemann","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23935,"journal":{"name":"Zeitschrift fur Immunitatsforschung. Immunobiology","volume":"153 3","pages":"236-47"},"PeriodicalIF":0.0,"publicationDate":"1977-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12112875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tridacnin, a new mitogenic lectin from invertebrate sources. Tridacnin，一种来自无脊椎动物的新的有丝分裂凝集素。
Zeitschrift fur Immunitatsforschung. Immunobiology Pub Date : 1977-09-01
G Uhlenbruck, K Schumacher, G Steinhausen, A Mil
{"title":"Tridacnin, a new mitogenic lectin from invertebrate sources.","authors":"G Uhlenbruck,&nbsp;K Schumacher,&nbsp;G Steinhausen,&nbsp;A Mil","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A new group of invertebrate lectins with anti-beta-galactosyl specificity, the so-called Tridacnins from the Tridacnid bivalve clams have been found to show not only agglutinating and precipitating properties, but also mitogenic activity as tested with human lymphocytes.</p>","PeriodicalId":23935,"journal":{"name":"Zeitschrift fur Immunitatsforschung. Immunobiology","volume":"153 3","pages":"265-7"},"PeriodicalIF":0.0,"publicationDate":"1977-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11517621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adjuvant action of capsular polysaccharide of Klebsiella pneumoniae on antibody response. VI. Site of its action. 肺炎克雷伯菌荚膜多糖对抗体应答的佐剂作用。六、作用地点。
Zeitschrift fur Immunitatsforschung. Immunobiology Pub Date : 1977-09-01 DOI: 10.1016/S0340-904X(77)80002-X
I. Nakashima, F. Nagase, N. Kato
{"title":"Adjuvant action of capsular polysaccharide of Klebsiella pneumoniae on antibody response. VI. Site of its action.","authors":"I. Nakashima, F. Nagase, N. Kato","doi":"10.1016/S0340-904X(77)80002-X","DOIUrl":"https://doi.org/10.1016/S0340-904X(77)80002-X","url":null,"abstract":"","PeriodicalId":23935,"journal":{"name":"Zeitschrift fur Immunitatsforschung. Immunobiology","volume":"29 1","pages":"204-16"},"PeriodicalIF":0.0,"publicationDate":"1977-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83728298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Adjuvant action of capsular polysaccharide of Klebsiella pneumoniae on antibody response. VI. Site of its action. 肺炎克雷伯菌荚膜多糖对抗体应答的佐剂作用。六、作用地点。
Zeitschrift fur Immunitatsforschung. Immunobiology Pub Date : 1977-09-01
I Nakashima, F Nagase, N Kato
{"title":"Adjuvant action of capsular polysaccharide of Klebsiella pneumoniae on antibody response. VI. Site of its action.","authors":"I Nakashima,&nbsp;F Nagase,&nbsp;N Kato","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23935,"journal":{"name":"Zeitschrift fur Immunitatsforschung. Immunobiology","volume":"153 3","pages":"204-16"},"PeriodicalIF":0.0,"publicationDate":"1977-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11548744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Virion antigens introduced exogeneously into the cell membrane render syngeneic target cells susceptible for T cell-mediated cytolysis. 病毒粒子抗原外源导入细胞膜使同源靶细胞对T细胞介导的细胞溶解敏感。
Zeitschrift fur Immunitatsforschung. Immunobiology Pub Date : 1977-09-01
K Pfizenmaier, A Starzinski-Powitz, H Wagner, M Röllinghoff
{"title":"Virion antigens introduced exogeneously into the cell membrane render syngeneic target cells susceptible for T cell-mediated cytolysis.","authors":"K Pfizenmaier,&nbsp;A Starzinski-Powitz,&nbsp;H Wagner,&nbsp;M Röllinghoff","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Non-infectious sendai virus renders H-2 matched target cells susceptible to the lytic effect of sendai virus immune cytotoxic T lymphocytes. This observation suggests that exogeneous insertion of virion antigen in the membrane of the target cell is sufficient for T cell cytotoxicity. The finding is incompatible with the concept that H-2K or H-2D gene products of the target cells must be altered in their primary structure (pretranslational effect of the virus infection) for T cell-mediated cytolysis to occur.</p>","PeriodicalId":23935,"journal":{"name":"Zeitschrift fur Immunitatsforschung. Immunobiology","volume":"153 3","pages":"268-73"},"PeriodicalIF":0.0,"publicationDate":"1977-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11417201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Requirement for interactions between two subpopulations of T cells for helper cell induction in vitro. 体外辅助细胞诱导需要两个T细胞亚群之间的相互作用。
Zeitschrift fur Immunitatsforschung. Immunobiology Pub Date : 1977-09-01 DOI: 10.1016/S0340-904X(77)80003-1
M. Feldmann, P. Erb
{"title":"Requirement for interactions between two subpopulations of T cells for helper cell induction in vitro.","authors":"M. Feldmann, P. Erb","doi":"10.1016/S0340-904X(77)80003-1","DOIUrl":"https://doi.org/10.1016/S0340-904X(77)80003-1","url":null,"abstract":"","PeriodicalId":23935,"journal":{"name":"Zeitschrift fur Immunitatsforschung. Immunobiology","volume":"50 1","pages":"217-25"},"PeriodicalIF":0.0,"publicationDate":"1977-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77449565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
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