B细胞记忆早期动力学及T细胞对体外表达的影响。

G Kraal, D Boden
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摘要

为了研究B细胞对绵羊红细胞记忆的早期动力学,采用短时间体外培养小鼠脾细胞的方法。用抗θ血清处理T细胞,观察其对体外记忆表达的影响。在体内启动48小时内,部分B细胞群可以在体外不需要T细胞的帮助下,在二抗原接触后分化为能够产生IgG的细胞。体外培养需要抗原的存在。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Early kinetics of B cell memory and the influence of T cells on the expression in vitro.

To study the early kinetics of B cell memory to sheep erythrocytes mouse spleen cells were cultured after short priming times in vivo. The influence of T cells on the expression of memory in vitro was investigated by treatment with anti-theta serum. Within 48 hours of in vivo priming part of the B cell population can differentiate into cells capable of IgG production after secondary antigen contact in vitro without the help of T cells. The presence of antigen was required for the in vitro development.

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