Yakhak Hoeji最新文献_第7页

Risk Factors Associated with Bisphosphonates Related Osteonecrosis of the Jaw: A National Insurance Senior Cohort Database Study 与双膦酸盐相关的颌骨骨坏死相关的危险因素:一项国家保险老年人队列数据库研究

Yakhak Hoeji Pub Date : 2022-08-30 DOI: 10.17480/psk.2022.66.4.210

Jun Hyeob Kim, Tae Hyeok Kim, K. Lee

{"title":"Risk Factors Associated with Bisphosphonates Related Osteonecrosis of the Jaw: A National Insurance Senior Cohort Database Study","authors":"Jun Hyeob Kim, Tae Hyeok Kim, K. Lee","doi":"10.17480/psk.2022.66.4.210","DOIUrl":"https://doi.org/10.17480/psk.2022.66.4.210","url":null,"abstract":"Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe side effect of bisphosphonate, which is usually prescribed as a treatment for diseases such as multiple myeloma, bone metastases, osteoporosis, and Paget disease. To investigate the risk factors of BRONJ, we conducted a nested case-control study using the Korean National Insurance Health Service-senior cohort. Patients newly diagnosed with BRONJ were selected as the case group, while the control group included patients who were never diagnosed with BRONJ. A risk-set sampling method was used to select the control group using age, sex, the date of the first prescription of bisphosphonate, and follow-up duration. Of the 22,236 subjects, 4,455 were included in the case group. Arthrosis, rheumatoid arthritis, neuropathies, myocardial infarction, renal disease, cancer, liver disease, and tooth extraction were associated with a higher incidence of BRONJ than subjects without such conditions (aOR, 95% CI: 1.58 [1.47-1.71], 1.46 [1.30-1.63], 1.31 [1.20-1.42], 1.23 [1.01-1.49], 1.36 [1.10-1.68], 1.27 [1.12-1.45], 1.63 [1.10-2.43], and 1.64 [1.53-1.76] respectively). In conclusion, of the factors examined, we confirmed that liver disease and tooth extraction were related to an increased risk of BRONJ.","PeriodicalId":23923,"journal":{"name":"Yakhak Hoeji","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84660525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current Status of Pharmacist-run Personal Broadcasting and Pharmacists’ Perceptions on Self-regulation by Korean Pharmaceutical Association 韩国药学会药师个人广播现状及药师自律意识

Yakhak Hoeji Pub Date : 2022-06-30 DOI: 10.17480/psk.2022.66.3.152

Kathryn Lim, Hyun Jin Kim, H. Park, Hyunjoo Sohn

{"title":"Current Status of Pharmacist-run Personal Broadcasting and Pharmacists’ Perceptions on Self-regulation by Korean Pharmaceutical Association","authors":"Kathryn Lim, Hyun Jin Kim, H. Park, Hyunjoo Sohn","doi":"10.17480/psk.2022.66.3.152","DOIUrl":"https://doi.org/10.17480/psk.2022.66.3.152","url":null,"abstract":"With the rapid penetration of internet-based communication into all industries, YouTube®, a video-sharing platform, has come to be widely used in the healthcare field. This study aims to investigate the current status of pharmacist-run personal broadcast (PRPB) in Korea and explore the underlying perceptions held by pharmacists. YouTube searches made from May to June 2020 and June 2022 were analyzed, followed by a cross-sectional questionnaire survey during July 2020. A 13-item questionnaire was distributed via social media channels to recruit pharmacists using the convenience sampling method. Currently, there are a total of 91 PRPB channels on YouTube, most of which were started after 2019. Of the total 1267 contents, health functional foods (32.4%) and over the counter products (29.3%) had the highest proportions. Among the 218 respondents of the questionnaire survey, 49.1% were working in community pharmacies, and only 2.8% had PRPB experience. They showed higher positive response (42.2%) than negative (33.5%) for the public's exposure to PRPB, and 77.5% of the respondents perceived that social influence of PRPB will grow bigger. Their concerns about PRPB were mainly disclosure of biased information and possibility to lead to product purchase (75.2%) and spreading unverified information (70.2%). In addition, 70.6% of the respondents agreed with the necessity of self-regulation of PRPB by the Korean Pharmaceutical Association and chose the operation of a civil petition counter to report the transmission of false or incorrect information on YouTube (62.8%) and composition of deliberation committee and periodic monitoring (53.2%) as regulatory methods. Perceived necessity of self-regulation was significantly higher in the above-50s age group than in the under-40s group (p<0.05). Pharmacists interested in PRPB should deliver accurate information as drug information providers and abide by professional ethics and public responsibility.","PeriodicalId":23923,"journal":{"name":"Yakhak Hoeji","volume":"107 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83071638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective Effect of Angelica gigas Nakai Extract Against Blue Light-induced Cell Death on Human Retinal Pigmented Epithelium (ARPE-19) Cell Viability 当归提取物抗蓝光致细胞死亡对人视网膜色素上皮(ARPE-19)细胞活力的保护作用

Yakhak Hoeji Pub Date : 2022-06-30 DOI: 10.17480/psk.2022.66.3.146

Hyeon Woo Kim, Youn Je Lee, H. Kang, Hyeong-Hoi Kim, Il Dae Song, J. Kang

{"title":"Protective Effect of Angelica gigas Nakai Extract Against Blue Light-induced Cell Death on Human Retinal Pigmented Epithelium (ARPE-19) Cell Viability","authors":"Hyeon Woo Kim, Youn Je Lee, H. Kang, Hyeong-Hoi Kim, Il Dae Song, J. Kang","doi":"10.17480/psk.2022.66.3.146","DOIUrl":"https://doi.org/10.17480/psk.2022.66.3.146","url":null,"abstract":"Light pollution such as blue light exposure can damage the visual photoreceptors and lead to cell death and degenerative retinal diseases. Despite the increasing number of patients suffering from retinal disease, the therapeutic agents are still insufficient. Angelica gigas Nakai extract (AGNEX) containing a high proportion of decursin derivatives has effectively protected cells under oxidative stress or high-level blue light. However, it remains unclear whether it protects retinal cells effectively. Here, we investigated the cytoprotective effect of AGNEX on retinal cells damaged using reactive oxygen species (ROS), which decreased the viability of retinal cells by causing oxidative stress. The cell viability with 600 μM hydrogen peroxide treatment was less than 70% of the normal control group. However, the group treated with 40 μM of AGNEX showed recovery as the normal control group. ROS levels were decreased in the AGNEX treated at 10-20 μM compared with the 600 μM hydrogen peroxide group. The AGNEX treated group was reduced by 20% compared with the untreated control group. This study suggests that AGNEX could prevent damage to blue light-induced retinal cells by oxidative stress relief, suggesting its potential as a therapeutic agent similar to eye care functional foods and as medicine against retinal cell damage.","PeriodicalId":23923,"journal":{"name":"Yakhak Hoeji","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85282198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Personality Types and Desired Career Fields of Pharmacy Students 药学专业学生的人格类型与理想职业领域

Yakhak Hoeji Pub Date : 2022-06-30 DOI: 10.17480/psk.2022.66.3.140

Bangsun Choi, Hyun-Mee Joung, P. Chun

{"title":"The Personality Types and Desired Career Fields of Pharmacy Students","authors":"Bangsun Choi, Hyun-Mee Joung, P. Chun","doi":"10.17480/psk.2022.66.3.140","DOIUrl":"https://doi.org/10.17480/psk.2022.66.3.140","url":null,"abstract":"This study was conducted to investigate the personality types and most desired career fields of pharmacy students. In this study, 31 first-year students, 28 third-year transfer students, and 32 fifth-grade students were analyzed, and 60.4% were female. Of 91 subjects, the introversion-sensing-thinking-judging (ISTJ) type was the most common, followed by introversion-sensing-thinking-perceiving (ISTP) and extraversion-sensing-thinking-judging (ESTJ). Thirty-five percent of first-graders, 42.9% of third-graders, and 53.1% of fifth-graders were extroverts and 64.5% of first-graders, 71.4% of thirdgraders, and 68.8% of fifth-graders belonged to the “sensing” personality type. Seventy-one percent of first-graders, 60.7% of third-graders, and 75% of fifth-graders belonged to the “thinking” type. Of 41 students wishing to work at community pharmacies, 51.2% were extroverts, 70.7% were “sensing,” 63.4% were “thinking,” and 51.2% were the “judging” type. Of 32 students who preferred hospital pharmacy, 40.6% were extroverts, 71.9% were “sensing,” 81.3% were “thinking,” and 53.1% were the “judging” type. Of 11 students wishing to work in pharmaceuticals, 36.4% were extroverts, 63.6% were “sensing,” 63.6% were “thinking,” and 72.7% were the “perceiving” type. Of seven students who preferred public institutions, 71.4% were introverts. When analyzing the correlation between personality types and the most desired career fields, no statistical significance was observed.","PeriodicalId":23923,"journal":{"name":"Yakhak Hoeji","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77647717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current Trends in Causes and Mechanisms of Pruritus Induced by Systemic Diseases 全身性疾病引起的瘙痒的病因和机制的最新进展

Yakhak Hoeji Pub Date : 2022-06-30 DOI: 10.17480/psk.2022.66.3.115

Sohyung Park, W. Shim

引用次数: 0

Public Health Emergency Preparedness and Response by Regulatory Authorities in South Korea, United States, and Europe 韩国、美国和欧洲监管当局的突发公共卫生事件准备和应对

Yakhak Hoeji Pub Date : 2022-06-30 DOI: 10.17480/psk.2022.66.3.125

Sunyoung Kim, Yeong-Gaung Han, EunHui Moon, SeokYeon Kang, Wongu Kang, J. Won, Si-Yeon Jeong

{"title":"Public Health Emergency Preparedness and Response by Regulatory Authorities in South Korea, United States, and Europe","authors":"Sunyoung Kim, Yeong-Gaung Han, EunHui Moon, SeokYeon Kang, Wongu Kang, J. Won, Si-Yeon Jeong","doi":"10.17480/psk.2022.66.3.125","DOIUrl":"https://doi.org/10.17480/psk.2022.66.3.125","url":null,"abstract":"Since the outbreak of the new strain of coronavirus (SARS-CoV-2, COVID-19) was first reported, regulatory authorities worldwide have issued various regulatory guidelines and recommendations. Global authorities are committed to supporting developers of potential vaccines and treatments for COVID-19. This study reviewed the guidelines and regulatory procedures instituted by authorities in the United States and Europe to understand the current perspectives of regulatory agencies worldwide and derive implications for public health emergency responses. The Act on Encouragement of Development and Emergency Circulation of Medical Countermeasures for public health emergencies enacted in 2021 established the Ministry of Food and Drug Safety (MFDS) to oversee policies for public health emergencies. In the US, the Public Law 113-5, the PHS Act, the PREP Act and the FD&C Act grant authorities emergency use power with respect to medical countermeasures needed during public health emergencies. The FDA can also facilitate the use of those medical countermeasures. The EMA has accelerated regulatory procedures in place for expediting the development and approval of medicinal products for COVID-19. The EMA’s rapid procedure includes rolling review, accelerated assessment and conditional marketing authorisation. Based on the review of foreign policies and practices regarding public health emergencies, this study showed that the Act on Encouragement of Development and Emergency Circulation of Medical Countermeasures for public health emergency responses has made important advances in public health emergency preparedness and response.","PeriodicalId":23923,"journal":{"name":"Yakhak Hoeji","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83063890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adverse Events Analysis and Signal Detection of Baricitinib and Tocilizumab, using KIDS-KD: Focusing on the Adverse Events that may Affect COVID-19 基于KIDS-KD的Baricitinib和Tocilizumab不良事件分析和信号检测:关注可能影响COVID-19的不良事件

Yakhak Hoeji Pub Date : 2022-04-30 DOI: 10.17480/psk.2022.66.2.49

Ji-Young Hur, Ju-Young Shin

引用次数: 0

The Development of Gastro-Retentive Tablet using Hot Melt Extrusion and 3D Printing Technology 利用热熔挤压和3D打印技术研制胃保留片

Yakhak Hoeji Pub Date : 2022-04-30 DOI: 10.17480/psk.2022.66.2.76

S. Lee, Young ho Cho, Gye-Won Lee

引用次数: 1

Trends in the Consumption of Anti-dementia Drugs by Region, Provider Type, and Diagnostic Code in South Korea 韩国按地区、提供者类型和诊断代码划分的抗痴呆药物消费趋势

Yakhak Hoeji Pub Date : 2022-04-30 DOI: 10.17480/psk.2022.66.2.58

S.Y. Chung, Hye-Jae Lee