Current Trends in Causes and Mechanisms of Pruritus Induced by Systemic Diseases

Sohyung Park, W. Shim
{"title":"Current Trends in Causes and Mechanisms of Pruritus Induced by Systemic Diseases","authors":"Sohyung Park, W. Shim","doi":"10.17480/psk.2022.66.3.115","DOIUrl":null,"url":null,"abstract":"Pruritus is a sensation that evokes a desire to scratch the skin. In particular, pruritus can be a burden for affected people when it becomes severe and chronic, as it deteriorates the quality of life. Dermatological diseases such as atopic dermatitis are mostly recognized as major pruritus-related disorders. Surprisingly, some non-dermatological systemic diseases can also evoke pruritus. In this review, we summarized the underlying causes and mechanisms of three nondermatological pruritus-related systemic diseases: including chronic kidney disease, cholestatic liver disease, and neoplasm. In addition, recent research observations and novel therapeutic strategies are discussed.","PeriodicalId":23923,"journal":{"name":"Yakhak Hoeji","volume":"87 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Yakhak Hoeji","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17480/psk.2022.66.3.115","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Pruritus is a sensation that evokes a desire to scratch the skin. In particular, pruritus can be a burden for affected people when it becomes severe and chronic, as it deteriorates the quality of life. Dermatological diseases such as atopic dermatitis are mostly recognized as major pruritus-related disorders. Surprisingly, some non-dermatological systemic diseases can also evoke pruritus. In this review, we summarized the underlying causes and mechanisms of three nondermatological pruritus-related systemic diseases: including chronic kidney disease, cholestatic liver disease, and neoplasm. In addition, recent research observations and novel therapeutic strategies are discussed.
全身性疾病引起的瘙痒的病因和机制的最新进展
瘙痒症是一种让人想抓挠皮肤的感觉。特别是,当瘙痒变得严重和慢性时,它会恶化生活质量,对受影响的人来说可能是一种负担。皮肤疾病,如特应性皮炎,大多被认为是主要的瘙痒相关疾病。令人惊讶的是,一些非皮肤系统疾病也能引起瘙痒。在这篇综述中,我们总结了三种与皮肤瘙痒相关的系统性疾病的潜在原因和机制:包括慢性肾病、胆汁淤积性肝病和肿瘤。此外,还讨论了最近的研究结果和新的治疗策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信