{"title":"全身性疾病引起的瘙痒的病因和机制的最新进展","authors":"Sohyung Park, W. Shim","doi":"10.17480/psk.2022.66.3.115","DOIUrl":null,"url":null,"abstract":"Pruritus is a sensation that evokes a desire to scratch the skin. In particular, pruritus can be a burden for affected people when it becomes severe and chronic, as it deteriorates the quality of life. Dermatological diseases such as atopic dermatitis are mostly recognized as major pruritus-related disorders. Surprisingly, some non-dermatological systemic diseases can also evoke pruritus. In this review, we summarized the underlying causes and mechanisms of three nondermatological pruritus-related systemic diseases: including chronic kidney disease, cholestatic liver disease, and neoplasm. In addition, recent research observations and novel therapeutic strategies are discussed.","PeriodicalId":23923,"journal":{"name":"Yakhak Hoeji","volume":"87 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Current Trends in Causes and Mechanisms of Pruritus Induced by Systemic Diseases\",\"authors\":\"Sohyung Park, W. Shim\",\"doi\":\"10.17480/psk.2022.66.3.115\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Pruritus is a sensation that evokes a desire to scratch the skin. In particular, pruritus can be a burden for affected people when it becomes severe and chronic, as it deteriorates the quality of life. Dermatological diseases such as atopic dermatitis are mostly recognized as major pruritus-related disorders. Surprisingly, some non-dermatological systemic diseases can also evoke pruritus. In this review, we summarized the underlying causes and mechanisms of three nondermatological pruritus-related systemic diseases: including chronic kidney disease, cholestatic liver disease, and neoplasm. In addition, recent research observations and novel therapeutic strategies are discussed.\",\"PeriodicalId\":23923,\"journal\":{\"name\":\"Yakhak Hoeji\",\"volume\":\"87 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Yakhak Hoeji\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17480/psk.2022.66.3.115\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Yakhak Hoeji","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17480/psk.2022.66.3.115","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Current Trends in Causes and Mechanisms of Pruritus Induced by Systemic Diseases
Pruritus is a sensation that evokes a desire to scratch the skin. In particular, pruritus can be a burden for affected people when it becomes severe and chronic, as it deteriorates the quality of life. Dermatological diseases such as atopic dermatitis are mostly recognized as major pruritus-related disorders. Surprisingly, some non-dermatological systemic diseases can also evoke pruritus. In this review, we summarized the underlying causes and mechanisms of three nondermatological pruritus-related systemic diseases: including chronic kidney disease, cholestatic liver disease, and neoplasm. In addition, recent research observations and novel therapeutic strategies are discussed.
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