Zentralblatt fur Veterinarmedizin. Reihe A最新文献

{"title":"[Estimate of the dosage for radioiodine ablation of the thyroid gland in male Wistar rats].","authors":"G Hanauer,&nbsp;H J Schroth","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this investigation was to determine the radioiodine dose necessary for the ablation of the thyroid gland in male Wistar rats. By a mathematical extrapolation of the kinetics of iodine-131, the radioisotope dose in the thyroid was calculated to be 467971 or 401540 rad after an intraperitoneal administration of 1 x 0.8 mCi (29.6 MBq) or 1 x 1.0 mCi (37.0 MBq) iodine-131, respectively. Because lower radioiodine activities did not result in a complete destruction of the thyroid (controlled by scintigraphic methods), it can be concluded that about 400,000 rad are necessary for the complete ablation of the thyroid gland by radioiodine.</p>","PeriodicalId":23904,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe A","volume":"37 10","pages":"747-51"},"PeriodicalIF":0.0,"publicationDate":"1990-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13282305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Comparative studies of the clearance of inulin and creatinine in swine].","authors":"M Wendt,&nbsp;K H Waldmann,&nbsp;K Bickhardt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Endogenous creatinine clearance was determined in 5 healthy female pigs of different body weight simultaneously to the clearance of inulin. The average creatinine clearance (3.74 +/- 0.57 mg/min/kg) has been found to be 7% higher than inulin clearance indicating some tubular secretion of creatinine. However, since this difference was not significant, the endogenous creatinine clearance is a practicable method for the measurement of glomerular filtration rate in swine. Data of creatinine concentration in plasma and of creatinine excretion showed close relationships to the body weight. It is discussed, whether the glomerular filtration rate can be predicted from the creatinine concentration in plasma and creatinine excretion, which might be estimated from the body weight without quantitative urine collection.</p>","PeriodicalId":23904,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe A","volume":"37 10","pages":"752-9"},"PeriodicalIF":0.0,"publicationDate":"1990-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13282834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Tibial dyschondroplasia in meat turkeys: morphometric study of its relationship with lameness].","authors":"Y Cherel,&nbsp;M Wyers,&nbsp;L Evain","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The tibiotarsal bones from 1,084 15-week-old growing commercial male turkeys, half of which clinically lame, were examined for dyschondroplasia. Lesions were a cone of retained cartilage, confined to the postero-medial area of the proximal metaphysis of the tibiotarsus. Dense woven bone was present around the largest lesions associated with thickening of the diaphyseal cortex below the lesion. Length of abnormal cartilage varied from 0.1 cm to 5.3 cm. Width never exceeded 2.9 cm. Half of the affected turkeys showed unilateral localization of dyschondroplastic lesions. The percentage of damaged tibias was 54 per cent and the percentage of affected turkeys was more than 70 per cent. The incidence of dyschondroplasia was the same in lame and clinically healthy turkeys but, on average, lame turkeys exhibited longer lesions than clinically normal birds. The tibias of lame turkeys were more curved than the tibias of healthy ones as well in the anterio-posterior projection as in the latero-medial one. The latero-medial projection of incurvation was correlated with the length of dyschondroplastic lesions.</p>","PeriodicalId":23904,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe A","volume":"37 9","pages":"676-85"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13282977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[IgM nephropathy (nephritis) in clawed monkeys (Primates, Anthropoidea, Platyrrhina, Callithricidae)].","authors":"M Brack","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A spontaneously occurring IgM-mediated mesangioproliferative nephropathy was detected in 91% of tamarins and marmosets over 6 months old. Intraglomerular IgM deposits could be demonstrated in all animals, usually in a mesangial pattern and in some cases along the glomerular endothelia. The clinical signs were hematuria and proteinuria. The progressive disease remains silent for long periods, but is directly or indirectly related to the death of 10-20% of the affected animals. Morphological characteristics are those of mesangial hyperplasia accompanied by subacute to chronic tubulointerstitial inflammation. The callithrid IgM-nephropathy is compared to similar human immunocomplex nephropathies.</p>","PeriodicalId":23904,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe A","volume":"37 9","pages":"692-707"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13282978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the adrenocortical response to both pharmacological and physiological stresses in sport horses.","authors":"A Linden,&nbsp;T Art,&nbsp;H Amory,&nbsp;D Desmecht,&nbsp;P Lekeux","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Seven sport horses were investigated to compare physiological and pharmacological stresses on the plasma glucocorticosteroid levels. Venous blood was sampled and analysed for cortisol concentrations before and after each type of stress. The physiological stress was induced by the completion of a cross-country and the pharmacological one, by an intravenous ACTH administration (200 micrograms) in the same horses, one week after the course. Both exercise and ACTH injection induced a highly significant cortisol increase of 79 +/- 0.10% and 160 +/- 0.18%, respectively. The relative plasma cortisol increases due to exercise on the one hand, and due to ACTH administration on the other hand, were correlated with a coefficient of 0.82. It was concluded that the plasma cortisol increase induced by a standardised pharmacological stress could be used in order to predict the exercise-induced stress response.</p>","PeriodicalId":23904,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe A","volume":"37 8","pages":"601-4"},"PeriodicalIF":0.0,"publicationDate":"1990-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13327894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Follow-up studies by peroral small intestinal biopsies and necropsy in dogs with chronic diarrhea.","authors":"I van der Gaag,&nbsp;R P Happé","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The results of follow-up studies in 82 dogs with clinical signs of chronic diarrhea are presented. Follow-up studies were performed by small intestinal biopsies only in 19 dogs, combined with necropsy in six dogs and follow-up necropsy only in 57 dogs. The times between the first and the last series of biopsies varied from 18 to 561 days, and from one to 656 days between the first series of biopsies and necropsy. From the 11 dogs with villous atrophy in the first series of biopsies, three also showed villous atrophy in the following biopsies or at necropsy, two had enteritis, one intestinal lymphangiectasia, one lymphosarcoma and four had no small intestinal lesions. Villous atrophy and enteritis found in 20 dogs in the initial biopsies were still present in 12 dogs in the following biopsies, in one only the villous atrophy remained in the following biopsies, in four lymphosarcoma was diagnosed, in one a colitis and in two changes outside the gastrointestinal tract were found at necropsy. In six of the seven dogs with enteritis in the initial biopsies this was diagnosed again, once with VA; in the seventh dog a hypertrophic gastritis was found. In five of the eight dogs with a diagnosis of lymphosarcoma in the initial biopsies a lymphosarcoma was found at necropsy, two had a villous atrophy with enteritis and in one only a differential diagnosis lymphosarcoma and/or enteritis could be made.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":23904,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe A","volume":"37 8","pages":"561-8"},"PeriodicalIF":0.0,"publicationDate":"1990-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13278361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The effect of the protein content of the diet on the resting and fasting oxygen consumption of albino rats].","authors":"C Henrich-Eberl,&nbsp;H Rufeger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The influence of the dietary protein concentration on the resting and fasting oxygen consumption (RNSV) was investigated on 71 male Wistar rats, at an environmental temperature of 28 degrees C. At the beginning of the first experiment the animals were either one, three or eight months old and weighed approximately 100, 300 or 500 g. They received a purified diet, containing a crude protein concentration of either 7 or 20%, for eight weeks; the protein carrier was wheat gluten. In the second experiment, carried our directly after the first one, only the animals weighing 500 g received Altromin stock diet for three weeks. Experiments on growing animals with different dietary protein concentrations, lead to considerable weight differences. Since the RNSV depends on the body mass, the experiments must be conducted in such a manner that the animals are of the same age, the same weight, and have been adapted to the diet for at least two weeks at the time the RNSV is measured. The experiments have shown that quantitative protein deficiency causes a greater reduction of the RNSV, the lighter or younger the animals are. On the other hand they have shown that the intraspecific relation between RNSV and body mass depends on the protein concentration of the diet. Consequently, this causes the value of the intraspecific body mass exponent to grow with a decrease in the dietary protein concentration, which in turn limits the animals growth. The results of this investigation cannot be explained by diet induced thermogenesis (DIT) of proteins. However, they support the hypothesis that quantitative protein deficiency decreases the calorigenic action of the thyroid gland.</p>","PeriodicalId":23904,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe A","volume":"37 8","pages":"622-33"},"PeriodicalIF":0.0,"publicationDate":"1990-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13278362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The effect of glucocorticoids on glucose metabolism in pygmy goats. 2. Glucose turnover and recycling].","authors":"N Sandner,&nbsp;M Stangassinger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the present study glucose kinetic parameters like pool size, distribution volume and rates of total entry and irreversible loss were determined in four castrated male African pygmy goats during hyperglycemia induced by an intravenous glucocorticoid injection (0.25 mg dexamethasone = DXM per kg body weight). Experiments were done at two different metabolic states, \"fed\" once daily and \"fasted\" after three days of starvation. The use of [U-14C]- together with [2-3H]- or [6-3H]-glucose made it possible to show changes in rates of gluconeogenesis, phosphorylation and specific recycling of glucose-C (e.g. lactate/alanine). During glucocorticoid induced hyperglycemia (+45%) in fed animals de novo synthesis of glucose (+5%) and lactate/alanine recycling increased (+4%). Rates of irreversible loss for all applied tracers in fasted animals formed only two thirds of the values of fed animals. During hyperglycemia (+40%) after DXM-injection de novo synthesis of glucose (+8%) and lactate/alanine recycling also increased (+27%). Furthermore the rate of phosphorylation of glucose decreased in fasted pygmy goats. The increase in availability of glucose both in fed and fasted animals is due to an increase in gluconeogenesis. In fasted animals additionally a decrease in the rate of phosphorylation and therefore of the peripheral glucose turnover has to be considered.</p>","PeriodicalId":23904,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe A","volume":"37 7","pages":"537-48"},"PeriodicalIF":0.0,"publicationDate":"1990-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13277176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Determination of cortisol, T4, T3 and T-uptake in serum and plasma of horses using fluorescence polarization immunoassays (FIPAs)].","authors":"A Lindner,&nbsp;Y Will,&nbsp;E Wilkniss,&nbsp;J Chrispeels","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The influence of duration and temperature of storage on hormone levels of whole blood, plasma and serum of horses was investigated. Using FPIAs cortisol, T4 and T-uptake could be measured while the T3-FPIA did not work appropriately. Serum and Plasma stored under the same conditions did not show any difference in cortisol, T4 and T-uptake values. In frozen heparinized plasma samples analysed on different days the cortisol and T4 concentrations fluctuated markedly. The T-uptake values were rather stable. The smallest day by day changes of cortisol and T4 in plasma were found when storing the samples at 20-22 degrees C. At 4 degrees C cortisol decreased markedly while for T4 a clear trend was not found. The cortisol concentration in whole blood stored at 4 degrees C decreased more markedly than in samples stored at 20-22 degrees C. T4 remained stable in whole blood samples stored at 20-22 degrees C over 4 days while showing fluctuations in samples stored at 4 degrees C.</p>","PeriodicalId":23904,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe A","volume":"37 6","pages":"455-62"},"PeriodicalIF":0.0,"publicationDate":"1990-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13275920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The histological appearance of peroral small intestinal biopsies in clinically healthy dogs and dogs with chronic diarrhea.","authors":"I van der Gaag,&nbsp;R P Happé","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A survey of the histology of 2,024 small intestinal suction and forceps biopsies in 400 dogs, consisting of 17 clinically healthy control dogs and 383 dogs with chronic diarrhea is presented. Three and a half percent of the suction biopsies and 22.6 percent of the forceps biopsies were unsuitable for examination, making a diagnosis impossible in 9 dogs, and in 0.4 percent antral mucosa was present. Biopsies could be obtained from the proximal one third of the small intestine. The normal histology, including mean villous length, its standard deviation and its range is described in the 17 control dogs. A classification of enteritis in dogs is given. Villous atrophy without enteritis was found in 55 dogs with chronic diarrhea; 51 dogs had moderate and four severe villous atrophy. Villous atrophy combined with enteritis was found in 93 dogs, 57 of which had lymphocytic-plasmacytic enteritis, 14 had eosinophilic enteritis, six catarrhal, four ulcerative, 11 a combination of lymphocytic-plasmacytic and eosinophilic enteritis and one dog had a combination of lymphocytic-plasmacytic and catarrhal enteritis. Enteritis without villous atrophy was found in 50 dogs: 39 had lymphocytic-plasmacytic enteritis, four eosinophilic, two catarrhal, one purulent (microabscesses), three a combination of lymphocytic-plasmacytic and eosinophilic enteritis and one dog had focal necrosis. Twelve dogs showed a lymphosarcoma and in eight other dogs a differential diagnosis of lymphosarcoma and/or enteritis was made. One carcinoma was found. Other findings were hemorrhages, oedema, erosions, muscular hypertrophy in the villi, an increased or decreased number of intraepithelial lymphocytes, an increased or decreased number of goblet cells, lymphangiectasia, crypt cysts, crypt abscesses and gastric metaplasia. Some breeds, such as the German Shepherd dog, Bouvier des Flandres, Spaniel, Collie, Great Dane and Retriever appear to be more susceptible than other breeds for villous atrophy and enteritis. A slight prevalence of the German Shepherd dog, Doberman Pinscher and Rottweiler was also observed for eosinophilic enteritis. Mild villous atrophy is mostly found in dogs aged 0-4 years, whereas severe villous atrophy is found in dogs older than 4 years. Further breed, age or sex predisposition could not be found. The method appears especially useful for diffuse mucosal lesions of the proximal small intestine.</p>","PeriodicalId":23904,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe A","volume":"37 6","pages":"401-16"},"PeriodicalIF":0.0,"publicationDate":"1990-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13275329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}