{"title":"[雄性Wistar大鼠甲状腺放射性碘消融剂量的估计]。","authors":"G Hanauer, H J Schroth","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The aim of this investigation was to determine the radioiodine dose necessary for the ablation of the thyroid gland in male Wistar rats. By a mathematical extrapolation of the kinetics of iodine-131, the radioisotope dose in the thyroid was calculated to be 467971 or 401540 rad after an intraperitoneal administration of 1 x 0.8 mCi (29.6 MBq) or 1 x 1.0 mCi (37.0 MBq) iodine-131, respectively. Because lower radioiodine activities did not result in a complete destruction of the thyroid (controlled by scintigraphic methods), it can be concluded that about 400,000 rad are necessary for the complete ablation of the thyroid gland by radioiodine.</p>","PeriodicalId":23904,"journal":{"name":"Zentralblatt fur Veterinarmedizin. Reihe A","volume":"37 10","pages":"747-51"},"PeriodicalIF":0.0000,"publicationDate":"1990-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Estimate of the dosage for radioiodine ablation of the thyroid gland in male Wistar rats].\",\"authors\":\"G Hanauer, H J Schroth\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The aim of this investigation was to determine the radioiodine dose necessary for the ablation of the thyroid gland in male Wistar rats. By a mathematical extrapolation of the kinetics of iodine-131, the radioisotope dose in the thyroid was calculated to be 467971 or 401540 rad after an intraperitoneal administration of 1 x 0.8 mCi (29.6 MBq) or 1 x 1.0 mCi (37.0 MBq) iodine-131, respectively. Because lower radioiodine activities did not result in a complete destruction of the thyroid (controlled by scintigraphic methods), it can be concluded that about 400,000 rad are necessary for the complete ablation of the thyroid gland by radioiodine.</p>\",\"PeriodicalId\":23904,\"journal\":{\"name\":\"Zentralblatt fur Veterinarmedizin. Reihe A\",\"volume\":\"37 10\",\"pages\":\"747-51\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zentralblatt fur Veterinarmedizin. Reihe A\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zentralblatt fur Veterinarmedizin. Reihe A","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Estimate of the dosage for radioiodine ablation of the thyroid gland in male Wistar rats].
The aim of this investigation was to determine the radioiodine dose necessary for the ablation of the thyroid gland in male Wistar rats. By a mathematical extrapolation of the kinetics of iodine-131, the radioisotope dose in the thyroid was calculated to be 467971 or 401540 rad after an intraperitoneal administration of 1 x 0.8 mCi (29.6 MBq) or 1 x 1.0 mCi (37.0 MBq) iodine-131, respectively. Because lower radioiodine activities did not result in a complete destruction of the thyroid (controlled by scintigraphic methods), it can be concluded that about 400,000 rad are necessary for the complete ablation of the thyroid gland by radioiodine.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
