{"title":"Prevalence of Patent Foramen Ovale in Ischemic Stroke Patients Over 60 Years of Age","authors":"Lamia Bencherif, Olivier Heinzlef, N. Ajili","doi":"10.33425/2639-8486.1168","DOIUrl":"https://doi.org/10.33425/2639-8486.1168","url":null,"abstract":"Introduction: The patent foramen oval (PFO) prevalence is higher in young subjects with cryptogenic stroke compared to the general population, but there is not much information in subjects over 60 years old. The goal of this study is to estimate the prevalence of PFO in patients over 60 years of age managed at Centre hospitalier intercommunal de Poissy/Saint Germain en Laye (CHIPS) for an acute ischemic stroke (AIS) and compare these results to what has already been reported in the literature. Methods: It is a monocentric, observational, descriptive and retrospective study of a series of patients aged 60 to 80 years with ischemic stroke managed in the Neurovascular Intensive Care Unit of the CHIPS from September 1, 2020 to December 31, 2020. We excluded from our series AIS of identified non-cardio-embolic cause according to the TOAST classification. We have chosen to favour contrast TTE over TEE in our population of elderly subjects. Results: Among the 22 patients analysed (mean age of 72.3 years), 7 patients received TEE and 15 patients received contrast TTE for PFO screening. In our series, we have a significant PFO prevalence of 12.5% in cryptogenic AIS (1 in 8 cryptogenic AIS), which corresponds to the prevalence reported in the literature in subjects over 60 years of age with cryptogenic AIS (13%). Conclusion: This is a preliminary descriptive study on the prevalence of PFO in elderly subjects with cryptogenic AIS in our center before undertaking further studies on the association between PFO and AIS in patients over 60 years of age, and eventually on the interest of PFO closure in this age group.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"194 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139367430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diop K.R, Ndao I Niasse A, Beye S.M, Mingou J.S, Diouf Y, Ndiaye P.G, Diop C.M.B, Samb C.A.B, Diouf M.T, A. F., Sarr S.A, Bodian M, Ndiaye M.B, A. Kane, D. M, K. A
{"title":"Epidemiological Aspects of Acute Coronary Syndromes in Saint-Louis, Senegal","authors":"Diop K.R, Ndao I Niasse A, Beye S.M, Mingou J.S, Diouf Y, Ndiaye P.G, Diop C.M.B, Samb C.A.B, Diouf M.T, A. F., Sarr S.A, Bodian M, Ndiaye M.B, A. Kane, D. M, K. A","doi":"10.33425/2639-8486.1155","DOIUrl":"https://doi.org/10.33425/2639-8486.1155","url":null,"abstract":"Introduction: The prevalence of cardiovascular diseases has been rapidly increasing in developing countries, leading to an increasing incidence of acute coronary syndrome which is becoming a major health concern. Few studies have been conducted in hospital settings, which has led us to conduct this cross-sectional, descriptive study in Saint Louis in the north of Senegal, (250 km away from the capital) whose objective is to describe the epidemiological aspects of acute coronary syndrome (ACS) in hospital settings. Methodology: This is a cross-sectional descriptive and retrospective study lasting two years from January 1, 2018 to 31 December 2019 which included all patients hospitalized in the cardiology department of the regional hospital of salary for an ACS. Results: Out of 475 patients admitted to the department of cardiology, 47 presented with acute coronary syndrome which is a prevalence of 9.89%. The mean age was 63+/-13.14 years. There was a male predominance with a sex ratio of 1.5. The meantime between the beginnings of symptoms to hospitalization was 50 hours. The most frequent clinical presentation was acute coronary syndrome with ST segment elevation (STEMI: ST-segment Elevation Myocardial Infarction) in 39 patients. Hypertension was the most common cardiovascular risk factor in 23 patients and chest pain was the most common symptoms 72.3%. In STEMI patients, the ECG abnormalities were mainly in the anterior region and in NSTEMI (Non-ST-segment Elevation Myocardial Infarction) patients the ECG abnormalities were mainly in the inferior region. On echocardiography, 64% of patients had an altered left ventricular ejection function in STEMI patients whereas in NSTEMI patients, the left ventricular ejection function was preserved in 71% of cases. STEMI patients received within the first 12 hours represented 66% of our population of which 84% benefited from thrombolysis with streptokinase with a success rate of 52%. The mean time to thrombolysis was six hours. Six patients or 12.76% were sent for coronarography. The most common complication was cardiovascular collapse (11%), 15% of patients died. Conclusion: The prevalence of acute coronary syndrome is increasing in West Africa with a predominance of ST segment elevation acute coronary syndromes. The main issues encountered were long leading times between onset of symptoms and hospital admission along with limited availability of medical facilities.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124596857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Percutaneous Coronary Intervention in Single Coronary Artery anomaly presenting with Acute Coronary Syndrome","authors":"Ajitkumar Krishna Jadhav, Digvijay Dilip Nalawade, Pratik Wadhokar, Joaquim Noguer, Gauri Pikale","doi":"10.33425/2639-8486.1156","DOIUrl":"https://doi.org/10.33425/2639-8486.1156","url":null,"abstract":"Single coronary artery is a rare but potentially devastating anomaly. Most cases are asymptomatic and found incidentally in patients that undergo coronary angiography. Such patients are more prone to acute coronary syndrome if an atherosclerotic plaque develops at the origin of the coronary ostia. We report an interesting case of single coronary artery arising from the right coronary cusp with anomalous origin of the left anterior descending and left circumflex coronary arteries that was found incidentally while evaluating a patient with acute coronary syndrome.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114331593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Role of Circulating Immune Complexes in Coronary Artery Lesions: Understanding possible Patho-Physiology in Kawasaki Disease Revisited","authors":"S. Philip, A. Jindal, K. R.","doi":"10.33425/2639-8486.1154","DOIUrl":"https://doi.org/10.33425/2639-8486.1154","url":null,"abstract":"Kawasaki disease (KD) is an acute self-limiting systemic vasculitis of unknown etiology affecting predominantly the coronary arteries. The role of circulating immune complexes (ICs) in the pathogenesis of KD has been studied using the sera of patients with KD. It has been proposed that ICs are triggered by single or multiple unknown causative agents as well as vasculitis. An outbreak of SARS CoV2 infection caused similar pathophysiology in producing vasculitis, and the RNA virus may have triggered signs and symptoms similar to KD. For clinicians and researchers alike, detecting the causative agents of KD remains a challenge. According to studies in animal models, type III hypersensitivity reactions caused by serum sickness are a prototype for immune complex vasculitis. The signs and symptoms of coronary artery dilation in swine are similar to those of KD. These models may be used to evaluate new pharmacological agents for KD. The pathogenesis of KD is complex and remains inadequately understood at present. However, circulating immune complexes may play a key role in the pathophysiology of KD and coronary artery vasculitis. Various therapeutic agents are being explored in the management of KD and these agents act at various stages of the production of pro-inflammatory cytokines and chemokines. In this review, we discuss recent developments on the pathogenesis of KD and provide insights into the innate immune response and mechanisms behind coronary artery damage in KD. We specifically explore the potential role of ICs in the pathogenesis of KD.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133699991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Local-Regional In-Country Differences of Ischaemic Heart Disease – Forgotten or Overlooked","authors":"Bhavsar R, Jakobsen Cj","doi":"10.33425/2639-8486.1157","DOIUrl":"https://doi.org/10.33425/2639-8486.1157","url":null,"abstract":"Objective: The number of cardiac interventions has increased massively and improved the outcome after cardiac events. The efforts during the last decades have proven effective with a falling incidence of new cardiovascular diseases. In a relatively uniform country with free tax supported medical treatment and a fully developed ambulance and helicopter service, percutaneous cardiac intervention (PCI) after acute coronary syndrome (ACS) or overall revascularization must be a good indicator of ischaemic heart disease (IHD) and geographical differences must reflect the area frequency of IHD. Thus, so far there has not been much focus on local in country differences, which could reveal new focus for treatments. Material and Methods: The mandatory Western Denmark Heart Registry (WDHR) was used to identify all adult cardiac procedure performed in 3 Danish regions from 2000-2020. The registry included 282,883 new patients entries of which 232,592 was grouped as IHD. Results: Steady increase in number of investigations was observed over 15 years with stabilization of the absolute number of interventions after 2005 with subsequent decrease in treatment fraction. Data demonstrated a comparable regional activity, but significant differences in the incidence of IHD between individual municipalities. Conclusion: The screening, investigation and intervention initiative during the last two decades has proven effective which is demonstrated by the falling incidence of new cardiovascular diseases. However, for further and faster achievements, rapidly growing use of prevention and treatment resources should be allocated to focussed areas by taking in-country differences in consideration.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133270971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endocarditis with No Valve Involvement? A Case of Superior Vena Cava Endocarditis, Rare but Serious Vascular Infection","authors":"Ziad Affas, A. Sreenivasan, Vijay S. Patel","doi":"10.33425/2639-8486.1150","DOIUrl":"https://doi.org/10.33425/2639-8486.1150","url":null,"abstract":"Patients with end-stage renal disease (ESRD) will likely need vascular access for hemodialysis, the vascular access increases the risk of having bloodstream infections such as Catheter-Related Bloodstream Infections (CRBSI). Rarely some patients may have non-valvular endocarditis. Fibrin sheath usually plays a role in this infection, and these can be identified on a transesophageal echocardiogram (TEE). ESRD patients can present without fever in cases of endocarditis due to uremia impaired cellular host defenses, therefore, a low threshold for TEE should be considered in these patients. We report a case of SVC endovascular endocarditis in the setting of MSSA bacteremia in an ESRD patient. A 49 -year-old female with a past medical history significant for ESRD secondary to diabetic nephropathy on dialysis with a tunneled subclavian hemodialysis dialysis catheter. Presented to the hospital for a chief complaint of fever for 2 days duration. The patient was vitally stable on admission; the area around the catheter was indurated and tender. The patient had a blood culture on the first day of her fever, it came back positive upon admission as the blood culture showed staphylococcus aureus bacteremia, and the patient was started on IV Vancomycin. Ultrasound was done and showed an abscess surrounding the dialysis port. TTE was done and showed no obvious evidence of endocarditis. TEE was done which demonstrated a large, mobile RA mass consistent with vegetation, which is attached at the lower junction of SVC and right interatrial septum. Angiovac of vegetation was done. The catheter was out. Blood culture sensitivity grew MSSA, susceptible to ancef, therefore vancomycin was switched to ancef 2g for a total of 6 weeks. Clinical suspicion should always be high for endocarditis in patients with fever and having dialysis catheter. TTE can be negative many times in these patients; therefore, having a high index of suspicion should always be there in these patients. Non-valvular endocarditis such as superior vena cava endocarditis is very uncommon and is only documented in a few cases in the literature. This infection responds very well to the antibiotic and Angiovac is helpful in these situations too.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"394 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115455525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Dioum, Papa H Diagne, Ziadath Assani, P. O. Ba, I. I. Moina-Hanifa, A. A. Ngaidé, S. Sy, M. Sarr, A. G. Ciss
{"title":"Rheumatic Heart Diseases: Epidemiological, Diagnostic and Therapeutic Aspects at The Cardiology Clinic Fann Hospital in Dakar","authors":"M. Dioum, Papa H Diagne, Ziadath Assani, P. O. Ba, I. I. Moina-Hanifa, A. A. Ngaidé, S. Sy, M. Sarr, A. G. Ciss","doi":"10.33425/2639-8486.1151","DOIUrl":"https://doi.org/10.33425/2639-8486.1151","url":null,"abstract":"Introduction: Rheumatic heart disease are a serious complication of acute articular rheumatism. They remain frequent in our underdeveloped countries and in Senegal in particular. Late diagnosis and lack of early and appropriate management put people at risk of serious and sometimes fatal complications. The purpose of our study was to report the epidemic profile and outcomes of rheumatic valve disease management. Methodology: We conducted a retrospective and descriptive study including patients hospitalized from January 1st, 2017 to June 31th, 2019 for rheumatic valve disease in cardiac surgery or medical cardiology department. The various parameters studied were epidemiological, diagnostic and prognostic data. Data analysis was done by the Statistical package for Social Sciences (SPSS) version18. Results: We collected 102 cases. The average age was 20.57. The Male/Female sex ratio was 1.12. Fifty-six patients were hospitalized for scheduled surgery, 43 for decompensated heart failure and 03 for infectious endocarditis. Mitral valve regurgitation was the most common valve disease (19.61%). Poly-valvular involvement was dominated by mitral disease and aortic valve regurgitation (32.35%). Seventy-five patients, or 73.5%, had received surgical treatment, including valve replacement in 67.15% of cases and valvuloplasties accounted for 37.83%. Percutaneous mitral commissurotomy was performed in 03 patients. The medical treatment was for heart failure and infectious endocarditis. The trend was favourable in 86.2% of cases. Twenty-eight patients were lost sight. Medium-term mortality was 13.7% or 14 patients. Conclusion: Rheumatic heart diseases remain common in our regions, they must be detected early for better management. The treatment is typically surgical but is often lacking hence the importance of the prevention of rheumatic arthritis.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124892303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Performance of Robotic-Assisted Coronary Angioplasty System Over Conventional/Manual PCI","authors":"N. J. Camm, Sherrie Singh","doi":"10.33425/2639-8486.1153","DOIUrl":"https://doi.org/10.33425/2639-8486.1153","url":null,"abstract":"Most percutaneous coronary intervention (PCI) might present hazards for patients, procedure operators, and the laboratory staff [1-3]. Due to complex nature of lesions and procedures, both patients and laboratory team may be subjected to exposure of longer procedural duration and radiation [3]. The long hours of standing for operators while wearing a lead apron commonly leads to exhaustion and injuries that frequently results in reduced performance and sub optimal clinical results [1]. A remote-control, robotic-assisted angioplasty system was developed to address some of the procedural challenges and occupational hazards associated with traditional PCI in addition to enhancing the degree of precision and control for the interventional procedure. A remote- control, robotic-assisted angioplasty system is used to address some of the procedural challenges and occupational hazards associated with traditional PCI. The objective of this study was to assess the safety and feasibility of the operating robotic system in patients undergoing elective PCI. This review summarises the safety and feasibility of a robotic angioplasty system in delivery and manipulation of coronary guidewires, balloons, and stents in patients undergoing PCI. Patients with coronary artery disease and clinical indication for elective PCI were enrolled. The coronary angioplasty procedure was performed with the CorPath 200 robotic system (Corindus, Inc.) The operating system consists of a remote interventional cockpit and a multicomponent bedside unit that contains advance, retract, and rotate guidewires within rapid exchange catheters. The primary endpoint was device clinical success (30% residual stenosis) with- out in-hospital major adverse cardiac events. The procedural success was defined as the ability of the system to complete all the planned angioplasty steps based on procedural segments.30 days follow up after angioplasty procedure was done. A total of 47 patients were enrolled in the study. Primary endpoint had been achieved in all patients. The success of the robotic system was 98.1% in completing 48 of 49 planned steps. No device or procedure-related complications were reported and no in-hospital or 30-day major adverse cardiac events were observed. We rated the robotic system performances as equal to as or better than manual procedures in 97.7% of the cases. Cardiologist’s radiation exposure was 97% lower than found at the standard table position. Our procedure results demonstrated better safety, feasibility and procedural effectiveness than manual operation. Besides, total operator exposure to radiation was quite low. However, a larger study is warranted to confirm the safety and effectiveness of robotic-assisted percutaneous coronary intervention.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125618544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. M, T. A W, D. M., B. Ho, F. D., Diall A.A, D. B, S. M., D. S, T. C A, K. A, D. M, C. M, S. A, Diarra Bi, D. M, Coulibaly Sm, S. H, Diarra Mb, M. I
{"title":"Experience of Interventional Cardiology At CHU ''Luxembourg'' In Bamako","authors":"T. M, T. A W, D. M., B. Ho, F. D., Diall A.A, D. B, S. M., D. S, T. C A, K. A, D. M, C. M, S. A, Diarra Bi, D. M, Coulibaly Sm, S. H, Diarra Mb, M. I","doi":"10.33425/2639-8486.1152","DOIUrl":"https://doi.org/10.33425/2639-8486.1152","url":null,"abstract":"Introduction: In the recent past, it was not possible to treat coronary disease in Mali due to a lack of technical facilities. All our coronary patients were evacuated to the Maghreb, France or the sub-region to receive adequate care. In 2019, the opening of an interventional cardiology room at the University Hospital \"Luxembourg\" and the training of a team has allowed the local management of a good number of Malians and foreigners suffering from coronary pathology. We report here the results of 30 months of activities. Methodology: We performed a perspective analysis of coronary angiograms and angioplasties performed in our center from September 2019 to February 2022. Clinical, paraclinical including angiographic data were collected and analyzed. Results: Between September 2019 and February 2022, 670 patients underwent coronary angiography, 262 of whom were followed by angioplasty. Male gender was predominant (72.6%), a sex ratio of 2.62. The mean age was 59 years and the 46-65 age group was the most dominant (50.24%). High blood pressure was the main cardiovascular risk factor (33.8%). Chronic coronary syndrome was the most frequent indication (59.8%) followed by coronary syndromes (38.3%). The radial route was used in 98%. Coronary angiography was pathological in 69%. Multitruncular lesions were predominant (35.5%) followed by monotruncular (32.8%). 39.10% of our patients underwent angioplasty. Complications were minimal (3%) and mortality was 2.03%. Conclusion: In our developing countries, we are witnessing an epidemiological transition with the decrease in infectious diseases and the emergence of non-communicable diseases, particularly coronary diseases. Their management requires an adequate technical platform, qualified human resources, and multidisciplinary collaboratio","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"145 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116862970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of the Renal Function Using Two Different Approaches for Primary Percutaneous Coronary Intervention: A Retrospective Cohort Study","authors":"Ahmed Gwefel, O. Louis, Ihab M. Yassin","doi":"10.33425/2639-8486.1148","DOIUrl":"https://doi.org/10.33425/2639-8486.1148","url":null,"abstract":"Background: Contrast-induced nephropathy (CIN) continues to be one of the most common major adverse side effects of cardiac catheterization, and is associated with short- and long-term morbidity and mortality. Since the trans-radial approach to coronary angiography was first reported in 1989, trans-radial access has been used for primary percutaneous coronary intervention (PCI) for approximately 20 years. There is a growing perception that, within the setting of intra-arterial procedures, there is a different risk factor for renal involvement when using radial or femoral access, with femoral access leading to the greatest risk because of its proximity to the high flow bed of the renal arteries. This study aimed to compare the degree of renal dysfunction by different indices in trans-radial and trans-femoral primary PCI. Materials and Methods: This study had been conducted in the cardiology department; the National Heart Institute during the period from September 2018 to February 2020. The study included 90 patients admitted to the hospital with acute myocardial infarction and underwent primary PCI either through a femoral or radial with the Cystatin C and serum creatinine measured before and 72 hours of primary PCI. Results: A statistical difference between both groups regarding CIN, with p-value=0.044 was found. There was no statistical difference between both groups after PCI regarding serum creatinine and cystatin C with p-value: 0.723 and 0.439, respectively. Concerning serum urea, there was statistical difference between both groups after PCI in the direction to be more in the radial group: it was 28.46 ± 13.89 mg/dl in femoral group and 30.06 ± 7.99 mg/dl in radial group (p=0.003). However, time to vascular access was easier with femoral group than with radial group with p-value < 0.001. Regarding complications, there were no statistical difference between two groups except for hematoma (p-value=0.026) Conclusion: The study showed significant results according to developing CIN between the two groups which is more in femoral approach. The study showed that serum cystatin C didn’t add value to diagnosis of CIN.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126901616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}