{"title":"Can the Use of Cardiology Medical Record to Deliver Educational Intervention Improve Care? On Behalf of TAPP Program: Thinking Approach Towards Physician Support in Patient Management","authors":"Langer A, Tan M, Goldin L, Langer G","doi":"10.33425/2639-8486.1175","DOIUrl":"https://doi.org/10.33425/2639-8486.1175","url":null,"abstract":"Background: Despite clear and concise practice guidelines, strategies for lowering LDL-C are often poorly adopted in clinical practice, and many patients fail to reach guideline-recommended levels despite physician education and quality improvement programs. We studied whether physician focussed, guideline-based practice level educational intervention can improve lipid lowering management. Methods: Cardiologists or internal medicine specialists from the province of Ontario, Canada who were using a cardiology specific EMR (CEREBRUM, WELL Health Technologies Corporation) were invited to participate. Practice level data of patients with history of acute coronary syndromes (ACS) and lipid profile were studied. Physicians were alerted when patients in their practice were not treated according to recommendations. The primary endpoint was proportion of patients achieving the recommended LDL-C level of below 1.8 mmol/L. Results: Of the invited 378 specialists, 178 agreed to participate and shared their practice involving 7,683 ACS patients who were 70.4 ± 10.3 years of age and 27.2% were women. Overall, 57.7% of patients had LDL-C < 1.8 mmol/L at the start of the program (1.84 ± 0.87 mmol/L) and 63.0% (1.75 ± 0.79 mmol/L) at the end of the program (p<0.0001). With respect to the lipid lowering therapy, statin therapy was used in 52.9% of patients at the start of the program and increased to 72.1% at the end (p<0.0001). The use of ezetimibe increased from 12.6% to 19.0% (p<0.0001) and the use of PCSK9i from 1.2% to 2.4% (p<0.0001). Conclusion: The results indicate the feasibility of using EMR as a platform to deliver educational intervention and overcoming treatment inertia and improving LDL-C lowering.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139307075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Genuine Non Compaction of the Left Ventricle: A Case Report","authors":"Dohou Serge Hugues Mahougnon, Sonou Arnaud, Adoco Joseph, Lawani Bolarin Pierre, Hounkponou Murielle, Agbo-Ola clarisse, C. Léopold","doi":"10.33425/2639-8486.1176","DOIUrl":"https://doi.org/10.33425/2639-8486.1176","url":null,"abstract":"Left ventricular noncompaction (LVNC) is a rare unclassified heart disease characterized by the presence of multiple left intraventricular trabeculations. We report the case of a 52-year-old man admitted to hospital with congestive heart failure, which revealed non-compaction of the left ventricle on the basis of the echocardiographic criteria of Jenni. The patient was treated and progressed favourably. Outpatient follow-up was organised.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139306619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Haemodynamic Responses and Effectiveness of Head Upright Tilt Test in Unexplained Syncope in Children","authors":"Saji Philip, A. Thachil","doi":"10.33425/2639-8486.1177","DOIUrl":"https://doi.org/10.33425/2639-8486.1177","url":null,"abstract":"Background: Vasovagal syncope is a benign condition, defined as a transient loss of consciousness and postural tone due to cerebral hypoperfusion. The Head Upright Tilt Test (HUTT) is widely used and has proven to be a practical tool for the diagnosis and treatment of syncope. In this study, we evaluated various hemodynamic responses obtained from the Head Upright Tilt Test and usefulness of HUTT in training for possible prevention of syncope in pediatric population. Methods: A total of 75 consecutive subjects aged 5 to 20-years affected by syncope or near syncope underwent head upright tilt testing over a 5-year period, from the single centre data base study between 2015 and 2019. Test results were classified as negative or positive. Positive cases were further classified into vaso-depressive, vasoinhibitory, and mixed hemodynamic reactions and were also followed up prospectively over a 3-year period. Results: Of the 75 cases studied 50.7% male and 49.3% female. Positives were 69.3% (n=52), and the remaining cases were negative for vaso-vagal syncope. Among HUTT-positive cases, the most common hemodynamic responses in the pediatric population were of the mixed type (52%), followed by the vasodepressive type (40%), vasoinhibitory (6%), and psychogenic causes (2%). HUTT-positive cases were followed up for 3-years, and the majority of patients (77%) had no significant symptoms during the follow-up in our syncope evaluation clinic. Conclusion: HUTT is an important investigation to differentiate unexplained syncope from other causes of unconsciousness in the pediatric population. The most common hemodynamic reactions obtained in tilt test were of the mixed type, followed by the vasodepressive type. The HUTT test may also be considered as training for possible prevention of further episodes of syncope in children.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139308958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claire Glen, Kirsty Mcdowell, Calum Milne, Kathryn Kirkpatrick, Jennifer Lochrie, Paul Welsh, Robin AP Weir
{"title":"Defining Myocardial Injury in COVID-19: Is Troponin Enough? The COVID-19 Disease and Cardiac Events (Covicare) Study","authors":"Claire Glen, Kirsty Mcdowell, Calum Milne, Kathryn Kirkpatrick, Jennifer Lochrie, Paul Welsh, Robin AP Weir","doi":"10.33425/2639-8486.1174","DOIUrl":"https://doi.org/10.33425/2639-8486.1174","url":null,"abstract":"Background: Myocardial injury is a complication of COVID-19 infection and is associated with adverse outcome, but the definition is variable and based on troponin elevation alone. We utilised a revised definition of myocardial injury using biomarkers, electrocardiography (ECG) and echocardiography and assessed its predictive efficacy. Methods and Results: 100 patients (age 64.8 ± 13.2yr, 53% female) with COVID-19 had admission highsensitivity c-troponin-T (hs-cTnT), N-terminal-pro-B-type-natriuretic-peptide (NTproBNP), interleukins (IL), tumour necrosis factor-α (TNFα), ECG and echocardiography. 51(53%) of patients had hs-cTnT >14ng/L; 10(20%) died vs 3(7%) without hs-cTnT elevation (p=0.059). 30-day major adverse cardiac events (MACE) increased with increasing hs-cTnT (HR 1.69 [1.0-2.86]; p=0.05). IL-6, IL-8 and TNFα were associated with 30-day MACE and were higher in those with hs-cTnT >14ng/L. 36(38%) of patients had an abnormal ECG, which was associated with higher NTproBNP (589 [211–1696] vs 146 [79–390]ng/L, p=0.001). 55 (71%) of 78 patients with interpretable echocardiograms were abnormal; NTproBNP was higher in those with abnormal echocardiography (390 [131-1118] vs 129 [96-460]ng/L, p=0.036). Combining hs-cTnT elevation with ECG and echocardiographic abnormalities identified a group with markedly elevated NTproBNP (1163 [565-3156] vs 147[78-404]ng/L, p<0.001). Conclusions: A refined definition of myocardial injury using ECG/echocardiography and biomarkers may identify higher risk patients with COVID-19.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139307316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarr Simon Antoine, Mingou Joseph Salvador, Seye Aliou, Aw Fatou, Diouf Youssou, Diop Khadimu Rassoul, Malick Ndiaye, Beye Serigne Mor, Ngaide Alioune Alassane, B. Malick, Ndiaye Mouhamadou Bamba, Mbaye Alassane, K. Adama, Diao Maboury, K. Abdoul
{"title":"Diagnostic and Therapeutic Challenges of NON-ST-Elevation Myocardial Infarction in Sub-Saharian Africa","authors":"Sarr Simon Antoine, Mingou Joseph Salvador, Seye Aliou, Aw Fatou, Diouf Youssou, Diop Khadimu Rassoul, Malick Ndiaye, Beye Serigne Mor, Ngaide Alioune Alassane, B. Malick, Ndiaye Mouhamadou Bamba, Mbaye Alassane, K. Adama, Diao Maboury, K. Abdoul","doi":"10.33425/2639-8486.1173","DOIUrl":"https://doi.org/10.33425/2639-8486.1173","url":null,"abstract":"Introduction: Non-ST-elevation myocardial infarction (NonSTEMI) is most often associated with a non-occlusive coronary lesion. However, mortality remains high. The aim of this study was to evaluate the diagnostic and evolutionary aspects of patients presenting with NonSTEMI. Patients and methods: This was a descriptive cross-sectional study conducted from January 01, 2021 to June 31, 2021 in the cardiology department of Aristide Le Dantec Hospital It included all patients hospitalized for NonSTEMI in the study period. The data studied were clinical, paraclinical, therapeutic and evolutionary. Results: A total of 52 patients were included. Mean age was 60.69 years, with extremes of 32 and 86 years. The most common risk factors were hypertension (58.85%), diabetes (34.62%) and smoking (30.7%). Chest pain was the main symptom (73.1%). On physical examination, signs of heart failure were noted in 19.2% of cases. Troponinemia was positive in 94.2% of patients. Repolarization disorders occurred most frequently in the lateral territory (55.4%). ST-segment depression was most common (75%). Doppler echocardiography revealed segmental kinetic disorders in 22 patients (42.3%). Coronary angiography was performed in 36 patients. Significant lesions were found in 63.8% of cases, most often tri-truncular (56.5%). Fourteen patients underwent angioplasty. In-hospital mortality was 3.8%. Conclusion: NonSTEMI is a frequent clinical form of acute coronary syndrome, occurring most often in high-risk patients. It is the expression of coronary lesions that are often severe.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Integrating Ultrasound-Derived Carotid Artery Stiffness in the Assessment of Cardiovascular Risk","authors":"J. Gedney, J. Ruddy","doi":"10.33425/2639-8486.1172","DOIUrl":"https://doi.org/10.33425/2639-8486.1172","url":null,"abstract":"Historically, pulse wave velocity (PWV) has been used to measure vascular stiffness, but is limited in its utility when certain vascular disease states are present, such as aneurysm or iliac stenosis. PWV can therefore only provide reliable assessment of global vascular stiffness in limited vascular pathology. Speckle tracking is a method of post-hoc ultrasound image analysis that can measure vascular stiffness in a more comprehensive manner. Evidence from in vitro as well as in vivo studies has validated these techniques in the assessment of strain, distensibility, modulus, and stiffness index (β) in the carotid arterial system. Unfortunately, despite the wellestablished correlation between vascular stiffness and cardiovascular morbidity and mortality, standard vascular laboratory ultrasound protocols do not include stiffness assessment. Herein, we present evidence in favor of integrating speckle tracking into carotid artery duplex protocols to measure vascular stiffness that can be utilized in medical management to modulate cardiovascular risk.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Danko Grujić, A. Djordjević, R. Karan, Jelena Čumić, Dejan Lazovic, Vladimir Milićević, Jacob Mulwa, D. Terzić
{"title":"Total Arterial Myocardial Revascularization - A One-Year Initial Experience and Literature Review","authors":"Danko Grujić, A. Djordjević, R. Karan, Jelena Čumić, Dejan Lazovic, Vladimir Milićević, Jacob Mulwa, D. Terzić","doi":"10.33425/2639-8486.1170","DOIUrl":"https://doi.org/10.33425/2639-8486.1170","url":null,"abstract":"We presented the results of the clinical outcomes of an isolated cohort of patients in whom coronary disease was treated with total arterial revascularization of the myocardium in the period of one year. We put a special focus on the preparation and use of the gastroepiploic artery as an in situ graft for revascularization of the right and posterior descending coronary arteries considering its less frequent application in cardiac surgery practice. We have shown selected reports of individual publications that we consider to unify the aforementioned strategic approach to treatment of coronary disease. According to the general trend in cardiac surgery to use minimally invasive approaches, part of the publication is dedicated to surgical revascularization through a left mini thoracotomy, where again arterial grafts are absolutely dominant.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Role of Cardiac Magnetic Resonance Imaging in Non-Ischemic Cardiomyopathies","authors":"Vu Tuan Nguyen","doi":"10.33425/2639-8486.1169","DOIUrl":"https://doi.org/10.33425/2639-8486.1169","url":null,"abstract":"Background: Nonischemic Cardiomyopathies including Myocarditis and Primary Cardiomyopathies as hypertrophic CMP, dilated CMP, restrictive CMP, noncompation CMP. Echocardiography is the intial evaluative method for CMP diagnosis, but it is limited by poor acoustic windows. Cardiac magnetic resonance imaging allows accurate assessment of myocardial anatomy, function and tissue characterization. End point of study: To review the ability of cardiac MRI in the diagnosis of nonischemic cardiomyopathies. Result: 185 patients with nonischemic cardiomyopathies of 243 patients underwent cardiac MRI with 1,5 Tesla GE Explorer at Medic HCMC, since October 2020 to April 2023. In which, 88% of primary CMP and 12% of Myocarditid were notified. Patients had CMR using the 1.5 Tesla GE Explorer and CVI 42 version 5.13.10, with the following protocol: Axial FIESTA, SA cine, 4C and 2C cine, T1 mapping with MOLLI, Triple IR FSE T2, myocardial perfusion imaging TI, LGE-MRI. Conclusion: Cardiac MRI has been useful imaging modality for assessment nonischemic cardiomyopathies with the high accuracy. Cardiac MRI is not only the establishing diagnosis but also prognosis.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139367692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Concomitant Cardiac Carcinoid and Amyloid in a Patient with a Caecal Neuro-Endocrine Tumour with Metastases","authors":"Gordon Pate, Evan Mannion, John Greally","doi":"10.33425/2639-8486.1167","DOIUrl":"https://doi.org/10.33425/2639-8486.1167","url":null,"abstract":"","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139367577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Majed Dwaik, Majd Bsharat, Ahmad Sandoka, S. Smerat
{"title":"Extra cardiac Findings on CT Coronary Angiography","authors":"Majed Dwaik, Majd Bsharat, Ahmad Sandoka, S. Smerat","doi":"10.33425/2639-8486.1166","DOIUrl":"https://doi.org/10.33425/2639-8486.1166","url":null,"abstract":"Incidental extracardiac findings are frequently seen on coronary computed tomography angiography (CCTA) which is increasingly used as an important tool of investigating stable chest pain. Incidental extracardiaac findings are noted during or after the procedure. Some of these findings are important to note and the patient need to be referred for further investigations or at least to be noted as a critical result to his or her referring physician. The objective of this retrospective study was to review, to analyze, and to quantify the spectrum and the prevalence of extracardiac findings in CCTA done in our hospital. These findings were categorized into clinically significant and clinically non-significant findings. The prevalence of the incidental extracardiac findings was calculated. Also, the life-threatening potential findings out of the total was calculated with their prevalence. A total of 486 exams were done in the period between March 2018 and Oct 2022. The average prevalence of overall Incidental extracardiac findings was 26.0% (92% confidence interval; P < .0001) and 12.0% (P < .0001) for clinically significant findings. Clinically significant ones of these findings were most commonly detected in the lungs (65.2%), the abdomen (16.7%), the vessels (8.1%), the mediastinum (10.6%), and in other adjacent anatomical territories (6.4%). The prevalence of acutely life-threatening and malignant cases accounted for 4% (P < .0001). In conclusion, clinically significant and acutely life-threatening ECF are not that common. Conclusion: Incidental extracardiac findings on CT coronary angiogram are may be detected with some of them are critically important. Prompt supervision and early reading will detect these findings with early dealing with them is an important task.","PeriodicalId":238598,"journal":{"name":"Cardiology & Vascular Research","volume":"212 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139367697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}