Zeitschrift fur Gastroenterologie最新文献

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S3-Leitlinie Diagnostik und Therapie des Hepatozellulären Karzinoms – Kurzversion. 肝细胞癌的诊断和治疗指南。
IF 1.4 4区 医学
Zeitschrift fur Gastroenterologie Pub Date : 2025-03-01 Epub Date: 2025-03-10 DOI: 10.1055/a-2446-2408
Michael Bitzer, Sabrina Groß, Jörg Albert, Susanne Blödt, Judit Boda-Heggemann, Katrin Borucki, Thomas Brunner, Reiner Caspari, Frank Dombrowski, Matthias Evert, Markus Follmann, Paul Freudenberger, Cihan Gani, Jamila Gebert, Andreas Geier, Eleni Gkika, Martin Götz, Thomas Helmberger, Ralf-Thorsten Hoffmann, Peter Huppert, David Krug, Christian La Fougère, Hauke Lang, Thomas Langer, Philipp Lenz, Tom Lüdde, Andreas Mahnken, Silvio Nadalin, Hoa Huu Phuc Nguyen, Monika Nothacker, Johann Ockenga, Karl Oldhafer, Julia Ott, Philipp Paprottka, Philippe Pereira, Thorsten Persigehl, Ruben Plentz, Jürgen Pohl, Heinrich Recken, Peter Reimer, Jutta Riemer, Kristina Ringe, Elke Roeb, Jörn Rüssel, Barbara Schellhaas, Peter Schirmacher, Hans Jürgen Schlitt, Irene Schmid, Kerstin Schütte, Andreas Schuler, Daniel Seehofer, Marianne Sinn, Andreas Stengel, Nadine Steubesand, Christoph Stoll, Andrea Tannapfel, Anne Taubert, Jörg Trojan, Ingo van Thiel, Martin Utzig, Arndt Vogel, Thomas Vogl, Frank Wacker, Oliver Waidmann, Heiner Wedemeyer, Henning Wege, Gregor Wenzel, Dane Wildner, Marcus-Alexander Wörns, Peter Galle, Nisar Malek
{"title":"S3-Leitlinie Diagnostik und Therapie des Hepatozellulären Karzinoms – Kurzversion.","authors":"Michael Bitzer, Sabrina Groß, Jörg Albert, Susanne Blödt, Judit Boda-Heggemann, Katrin Borucki, Thomas Brunner, Reiner Caspari, Frank Dombrowski, Matthias Evert, Markus Follmann, Paul Freudenberger, Cihan Gani, Jamila Gebert, Andreas Geier, Eleni Gkika, Martin Götz, Thomas Helmberger, Ralf-Thorsten Hoffmann, Peter Huppert, David Krug, Christian La Fougère, Hauke Lang, Thomas Langer, Philipp Lenz, Tom Lüdde, Andreas Mahnken, Silvio Nadalin, Hoa Huu Phuc Nguyen, Monika Nothacker, Johann Ockenga, Karl Oldhafer, Julia Ott, Philipp Paprottka, Philippe Pereira, Thorsten Persigehl, Ruben Plentz, Jürgen Pohl, Heinrich Recken, Peter Reimer, Jutta Riemer, Kristina Ringe, Elke Roeb, Jörn Rüssel, Barbara Schellhaas, Peter Schirmacher, Hans Jürgen Schlitt, Irene Schmid, Kerstin Schütte, Andreas Schuler, Daniel Seehofer, Marianne Sinn, Andreas Stengel, Nadine Steubesand, Christoph Stoll, Andrea Tannapfel, Anne Taubert, Jörg Trojan, Ingo van Thiel, Martin Utzig, Arndt Vogel, Thomas Vogl, Frank Wacker, Oliver Waidmann, Heiner Wedemeyer, Henning Wege, Gregor Wenzel, Dane Wildner, Marcus-Alexander Wörns, Peter Galle, Nisar Malek","doi":"10.1055/a-2446-2408","DOIUrl":"https://doi.org/10.1055/a-2446-2408","url":null,"abstract":"","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":"63 3","pages":"293-336"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Entirely Intramural Growth Pattern: A Rare Presentation of Esophageal Squamous Cell Carcinoma and Review of the Literature. 完全壁内生长模式:食管鳞状细胞癌的罕见表现及文献综述
IF 1.4 4区 医学
Zeitschrift fur Gastroenterologie Pub Date : 2025-02-01 Epub Date: 2024-11-25 DOI: 10.1055/a-2442-9540
Jiayu Qiu, Yi Tu, Chen Yu, Xu Shu, Xiaolin Pan, Yanxia Zhang
{"title":"Entirely Intramural Growth Pattern: A Rare Presentation of Esophageal Squamous Cell Carcinoma and Review of the Literature.","authors":"Jiayu Qiu, Yi Tu, Chen Yu, Xu Shu, Xiaolin Pan, Yanxia Zhang","doi":"10.1055/a-2442-9540","DOIUrl":"10.1055/a-2442-9540","url":null,"abstract":"<p><p>Esophageal squamous cell carcinoma (ESCC) is a malignant tumor originating from the squamous epithelium. In contrast, esophageal submucosal tumors are common benign lesions arising from mesenchymal tissues. To date, an entirely intramural growth of ESCC is very rare. This study described a case of an esophageal submucosal tumor resected by endoscopic submucosal dissection (ESD) that was finally diagnosed as ESCC.A 51-year-old woman presented with progressive dysphagia and was provisionally diagnosed with esophageal leiomyoma by further diagnostic modalities. The patient did not have any obvious suspicious malignant features and underwent ESD. However, the histopathology of the resected specimen was reported as poorly differentiated infiltrating squamous cell carcinoma with normal overlying squamous epithelium. Consequently, the patient received additional chemoradiotherapy, and no recurrence was observed during the 2-year follow-up.A comprehensive literature search related to ESCC with entirely intramural growth was performed in PubMed and Embase from their inception up to November 2023, and 12 articles including 13 cases were finally included in the literature review. Subsequently, we extracted information about these cases.It is concluded that ESCC may masquerade as a submucosal tumor with a complete submucosal growth pattern and is easily misdiagnosed because endoscopic biopsy and iodine staining are always negative. Therefore, if a patient with a submucosal tumor has dysphagia or weight loss in the short term, clinicians should be alert to the possibility of ESCC with a complete submucosal growth pattern. Endoscopic ultrasonography (EUS), chest computed tomography (CT), or positron emission tomography-computed tomography (PET-CT) may help assist in the diagnosis, and EUS-guided fine-needle aspiration (EUS-FNA) could be used to confirm the diagnosis.</p>","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":" ","pages":"145-154"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[57-year-old female patient with chronic left lower abdominal pain]. [女性,57岁,慢性左下腹痛]。
IF 1.4 4区 医学
Zeitschrift fur Gastroenterologie Pub Date : 2025-02-01 Epub Date: 2025-02-07 DOI: 10.1055/a-2446-1122
Abdul-Rahman Kabbani, Sebastian Schmidt, Johannes Beismann, Johannes Christoph, Dorothea Bielitz, Ludger Leifeld
{"title":"[57-year-old female patient with chronic left lower abdominal pain].","authors":"Abdul-Rahman Kabbani, Sebastian Schmidt, Johannes Beismann, Johannes Christoph, Dorothea Bielitz, Ludger Leifeld","doi":"10.1055/a-2446-1122","DOIUrl":"https://doi.org/10.1055/a-2446-1122","url":null,"abstract":"","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":"63 2","pages":"131-132"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Gastrointestinal manifestations of systemic mast cell activation disease - A practice-oriented guide to clinical picture, diagnostics and therapy]. [全身性肥大细胞活化病的胃肠道表现-临床图像、诊断和治疗的实践导向指南]。
IF 1.4 4区 医学
Zeitschrift fur Gastroenterologie Pub Date : 2025-02-01 Epub Date: 2025-01-03 DOI: 10.1055/a-2468-5553
Martin Raithel, Jürgen Homann, Ralf J Rieker, Gerhard J Molderings
{"title":"[Gastrointestinal manifestations of systemic mast cell activation disease - A practice-oriented guide to clinical picture, diagnostics and therapy].","authors":"Martin Raithel, Jürgen Homann, Ralf J Rieker, Gerhard J Molderings","doi":"10.1055/a-2468-5553","DOIUrl":"10.1055/a-2468-5553","url":null,"abstract":"<p><p>Systemic mast cell activation disease (MCAD) is an epigenetic and genetic disease entity with a very pronounced clinical symptomatology in a variety of clinical manifestations in potentially every organ and tissue due to inappropriate release of mast cell mediators accompanied with the accumulation of both morphologically normal and mutated mast cells. Due to the prevalence of the disease of 17% in Germany, gastroenterologists and endoscopists are often unknowingly faced with MCAD in everyday clinical practice. In addition, gastroenterological examinations are an essential part of the diagnosis of MCAD. It is therefore essential for every physician working in gastroenterology to possess basic knowledge of this disease and, in particular, to be informed about its problems in the field of gastroenterology. This overview summarizes the current state of knowledge on the causes, diagnosis and treatment of the highly complex MCAD, focusing on the gastroenterological aspects.</p>","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":"63 2","pages":"155-168"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Routine colonoscopy with a surprise in the cecum: It's a giant appendicolith! A Case report and review of the literature. 常规结肠镜检查发现盲肠内有一个惊喜:这是一块巨大的阑尾结石!病例报告和文献综述。
IF 1.4 4区 医学
Zeitschrift fur Gastroenterologie Pub Date : 2025-02-01 Epub Date: 2024-07-29 DOI: 10.1055/a-2349-2867
Magnus Kock Am Brink, Christa Schmidt, Thies Daniels, Guntram Lock
{"title":"Routine colonoscopy with a surprise in the cecum: It's a giant appendicolith! A Case report and review of the literature.","authors":"Magnus Kock Am Brink, Christa Schmidt, Thies Daniels, Guntram Lock","doi":"10.1055/a-2349-2867","DOIUrl":"10.1055/a-2349-2867","url":null,"abstract":"<p><p>Giant appendicoliths (defined as appendiceal stones larger than 2 cm in size) are rare findings, with less than 20 well-documented reported cases. Appendicoliths, in general, are linked to an increased risk of appendicitis and associated complications. However, little information is available on the clinical impact of giant appendicoliths. We present a case of a giant appendicolith accidentally discovered during screening colonoscopy. With more than 4 cm, this appendicolith is one of the largest of the few reported so far. In contrast to all other cases of giant appendicoliths, the patient did not exhibit any symptoms. Additionally, we provide an overview of giant appendicolith cases, discussing their clinical features, diagnosis, and treatment.</p>","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":" ","pages":"139-144"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
S3-Leitlinie Diagnostik und Therapie biliärer Karzinome – Kurzversion. 乳腺癌诊断与治疗指南。
IF 1.4 4区 医学
Zeitschrift fur Gastroenterologie Pub Date : 2025-02-01 Epub Date: 2025-02-07 DOI: 10.1055/a-2446-2454
Sabrina Groß, Michael Bitzer, Jörg Albert, Susanne Blödt, Judit Boda-Heggemann, Katrin Borucki, Thomas Brunner, Reiner Caspari, Frank Dombrowski, Matthias Evert, Markus Follmann, Paul Freudenberger, Cihan Gani, Jamila Gebert, Andreas Geier, Eleni Gkika, Martin Götz, Thomas Helmberger, Ralf-Thorsten Hoffmann, Peter Huppert, David Krug, Christian La Fougère, Hauke Lang, Thomas Langer, Philipp Lenz, Tom Lüdde, Andreas Mahnken, Silvio Nadalin, Hoa Huu Phuc Nguyen, Monika Nothacker, Johann Ockenga, Karl Oldhafer, Julia Ott, Philipp Paprottka, Philippe Pereira, Thorsten Persigehl, Ruben Plentz, Jürgen Pohl, Heinrich Recken, Peter Reimer, Jutta Riemer, Kristina Ringe, Elke Roeb, Jörn Rüssel, Barbara Schellhaas, Peter Schirmacher, Hans J Schlitt, Irene Schmid, Kerstin Schütte, Andreas Schuler, Daniel Seehofer, Marianne Sinn, Andreas Stengel, Nadine Steubesand, Christoph Stoll, Andrea Tannapfel, Anne Taubert, Jörg Trojan, Ingo van Thiel, Martin Utzig, Arndt Vogel, Thomas Vogl, Frank Wacker, Oliver Waidmann, Heiner Wedemeyer, Henning Wege, Gregor Wenzel, Dane Wildner, Marcus-Alexander Wörns, Peter Galle, Nisar Malek
{"title":"S3-Leitlinie Diagnostik und Therapie biliärer Karzinome – Kurzversion.","authors":"Sabrina Groß, Michael Bitzer, Jörg Albert, Susanne Blödt, Judit Boda-Heggemann, Katrin Borucki, Thomas Brunner, Reiner Caspari, Frank Dombrowski, Matthias Evert, Markus Follmann, Paul Freudenberger, Cihan Gani, Jamila Gebert, Andreas Geier, Eleni Gkika, Martin Götz, Thomas Helmberger, Ralf-Thorsten Hoffmann, Peter Huppert, David Krug, Christian La Fougère, Hauke Lang, Thomas Langer, Philipp Lenz, Tom Lüdde, Andreas Mahnken, Silvio Nadalin, Hoa Huu Phuc Nguyen, Monika Nothacker, Johann Ockenga, Karl Oldhafer, Julia Ott, Philipp Paprottka, Philippe Pereira, Thorsten Persigehl, Ruben Plentz, Jürgen Pohl, Heinrich Recken, Peter Reimer, Jutta Riemer, Kristina Ringe, Elke Roeb, Jörn Rüssel, Barbara Schellhaas, Peter Schirmacher, Hans J Schlitt, Irene Schmid, Kerstin Schütte, Andreas Schuler, Daniel Seehofer, Marianne Sinn, Andreas Stengel, Nadine Steubesand, Christoph Stoll, Andrea Tannapfel, Anne Taubert, Jörg Trojan, Ingo van Thiel, Martin Utzig, Arndt Vogel, Thomas Vogl, Frank Wacker, Oliver Waidmann, Heiner Wedemeyer, Henning Wege, Gregor Wenzel, Dane Wildner, Marcus-Alexander Wörns, Peter Galle, Nisar Malek","doi":"10.1055/a-2446-2454","DOIUrl":"https://doi.org/10.1055/a-2446-2454","url":null,"abstract":"","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":"63 2","pages":"169-203"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
S3-Leitlinie Diagnostik und Therapie biliärer Karzinome – Langversion. 肺癌诊断与治疗指南。
IF 1.4 4区 医学
Zeitschrift fur Gastroenterologie Pub Date : 2025-02-01 Epub Date: 2025-02-07 DOI: 10.1055/a-2460-6347
Sabrina Groß, Michael Bitzer, Jörg Albert, Susanne Blödt, Judit Boda-Heggemann, Katrin Borucki, Thomas Brunner, Reiner Caspari, Frank Dombrowski, Matthias Evert, Markus Follmann, Paul Freudenberger, Cihan Gani, Jamila Gebert, Andreas Geier, Eleni Gkika, Martin Götz, Thomas Helmberger, Ralf-Thorsten Hoffmann, Peter Huppert, David Krug, Christian La Fougère, Hauke Lang, Thomas Langer, Philipp Lenz, Tom Lüdde, Andreas Mahnken, Silvio Nadalin, Hoa Huu Phuc Nguyen, Monika Nothacker, Johann Ockenga, Karl Oldhafer, Julia Ott, Philipp Paprottka, Philippe Pereira, Thorsten Persigehl, Ruben Plentz, Jürgen Pohl, Heinrich Recken, Peter Reimer, Jutta Riemer, Kristina Ringe, Elke Roeb, Jörn Rüssel, Barbara Schellhaas, Peter Schirmacher, Hans Jürgen Schlitt, Irene Schmid, Kerstin Schütte, Andreas Schuler, Daniel Seehofer, Marianne Sinn, Andreas Stengel, Nadine Steubesand, Christoph Stoll, Andrea Tannapfel, Anne Taubert, Jörg Trojan, Ingo van Thiel, Martin Utzig, Arndt Vogel, Thomas Vogl, Frank Wacker, Oliver Waidmann, Heiner Wedemeyer, Henning Wege, Gregor Wenzel, Dane Wildner, Marcus-Alexander Wörns, Peter Galle, Nisar Malek
{"title":"S3-Leitlinie Diagnostik und Therapie biliärer Karzinome – Langversion.","authors":"Sabrina Groß, Michael Bitzer, Jörg Albert, Susanne Blödt, Judit Boda-Heggemann, Katrin Borucki, Thomas Brunner, Reiner Caspari, Frank Dombrowski, Matthias Evert, Markus Follmann, Paul Freudenberger, Cihan Gani, Jamila Gebert, Andreas Geier, Eleni Gkika, Martin Götz, Thomas Helmberger, Ralf-Thorsten Hoffmann, Peter Huppert, David Krug, Christian La Fougère, Hauke Lang, Thomas Langer, Philipp Lenz, Tom Lüdde, Andreas Mahnken, Silvio Nadalin, Hoa Huu Phuc Nguyen, Monika Nothacker, Johann Ockenga, Karl Oldhafer, Julia Ott, Philipp Paprottka, Philippe Pereira, Thorsten Persigehl, Ruben Plentz, Jürgen Pohl, Heinrich Recken, Peter Reimer, Jutta Riemer, Kristina Ringe, Elke Roeb, Jörn Rüssel, Barbara Schellhaas, Peter Schirmacher, Hans Jürgen Schlitt, Irene Schmid, Kerstin Schütte, Andreas Schuler, Daniel Seehofer, Marianne Sinn, Andreas Stengel, Nadine Steubesand, Christoph Stoll, Andrea Tannapfel, Anne Taubert, Jörg Trojan, Ingo van Thiel, Martin Utzig, Arndt Vogel, Thomas Vogl, Frank Wacker, Oliver Waidmann, Heiner Wedemeyer, Henning Wege, Gregor Wenzel, Dane Wildner, Marcus-Alexander Wörns, Peter Galle, Nisar Malek","doi":"10.1055/a-2460-6347","DOIUrl":"https://doi.org/10.1055/a-2460-6347","url":null,"abstract":"","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":"63 2","pages":"e82-e158"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Liver transplantation in alcohol-induced acute-on-chronic liver failure without six months of abstinence. 未戒酒6个月的酒精性急性慢性肝功能衰竭患者的肝移植
IF 1.4 4区 医学
Zeitschrift fur Gastroenterologie Pub Date : 2025-02-01 Epub Date: 2025-02-07 DOI: 10.1055/a-2497-1996
Falk Rauchfuss, Laura Schwenk, Philipp A Reuken, Alexander Zipprich, Sebastian Schwarz, Michael Bauer, Andreas Stallmach, Utz Settmacher
{"title":"Liver transplantation in alcohol-induced acute-on-chronic liver failure without six months of abstinence.","authors":"Falk Rauchfuss, Laura Schwenk, Philipp A Reuken, Alexander Zipprich, Sebastian Schwarz, Michael Bauer, Andreas Stallmach, Utz Settmacher","doi":"10.1055/a-2497-1996","DOIUrl":"10.1055/a-2497-1996","url":null,"abstract":"<p><p>Globally, many liver transplantation programs require adherence to a 6-month abstinence period in cases of alcohol-associated liver disease. Especially in cases of decompensation, such as acute-on-chronic liver failure (ACLF), the severity of the disease often makes it impossible to reach this interval, leading to increasing critical scrutiny of a fixed abstinence period. The prognostic relevance of the 6-month abstinence is also not firmly established.In the present study, we analyze all patients who were presented for liver transplantation at a German transplantation center due to acute-on-chronic liver failure caused by alcohol-associated liver disease.Retrospective analyses of patients with alcohol-associated liver disease who did not complete the 6-month abstinence period.Out of the 83 patients initially considered, 78 were included in the final analysis. The patients who underwent liver transplantation (n=16) had a significantly better 5-year survival rate (81.3% vs. 24.2%; p < 0.001). Especially in patients with ACLF and multiple organ dysfunctions (ACLF Grade 3), liver transplantation resulted in a significantly improved survival rate. Patients with an ACLF Grade 3 who were not transplanted died within the first six months after decompensation (92.5% mortality). All surviving transplant recipients continued abstaining from alcohol until the most recent evaluation point (average follow-up time 963 days).Patients experiencing acute-on-chronic liver failure from alcohol-related liver disease clearly benefit from liver transplantation, irrespective of whether they meet the 6-month abstinence criterion. This stipulated waiting period is increasingly debated in current discussions. Our findings emphasize that patients with ACLF, when not transplanted, face significant mortality risks. Such insights should be factored into tailored treatment decisions.</p>","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":"63 2","pages":"133-138"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[40-year-old-patient with perianal pain, signs of inflammation and stool retention]. [40岁,肛周疼痛,有炎症和大便潴留的征象]。
IF 1.4 4区 医学
Zeitschrift fur Gastroenterologie Pub Date : 2025-01-01 Epub Date: 2025-01-10 DOI: 10.1055/a-2446-1043
Martin Killermann, Edith Weigert, Marc Dauer
{"title":"[40-year-old-patient with perianal pain, signs of inflammation and stool retention].","authors":"Martin Killermann, Edith Weigert, Marc Dauer","doi":"10.1055/a-2446-1043","DOIUrl":"10.1055/a-2446-1043","url":null,"abstract":"","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":"63 1","pages":"29-30"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142965641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Percutaneous endoscopic gastrostomy in a 42-year-old patient with suspected variant of Creutzfeld Jakob disease using a disposable bronchoscope]. [使用一次性支气管镜为一名 42 岁疑似克雅氏病变异型患者进行经皮内镜胃造瘘术]。
IF 1.4 4区 医学
Zeitschrift fur Gastroenterologie Pub Date : 2025-01-01 Epub Date: 2024-11-25 DOI: 10.1055/a-2406-9419
Michael Klausner, Roman Feller, Wolfgang Vogt, Henning Wege
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