World Journal of Pediatric Surgery最新文献

Prenatal diagnosis and risk stratification of congenital diaphragmatic hernia. 先天性膈疝的产前诊断和风险分层。

IF 0.8 4区医学

World Journal of Pediatric Surgery Pub Date : 2024-10-16 eCollection Date: 2024-01-01 DOI: 10.1136/wjps-2024-000892

Nimrah Abbasi, Sami Backley, Greg Ryan, Anthony Johnson

{"title":"Prenatal diagnosis and risk stratification of congenital diaphragmatic hernia.","authors":"Nimrah Abbasi, Sami Backley, Greg Ryan, Anthony Johnson","doi":"10.1136/wjps-2024-000892","DOIUrl":"10.1136/wjps-2024-000892","url":null,"abstract":"Congenital diaphragmatic hernia (CDH) is a rare heterogenous disorder with varying degrees of severity. Infant survival rates in high-income countries are approaching 80% in isolated CDH; however, over 50% will have long-term morbidities. Advanced antenatal imaging, including ultrasound and magnetic resonance imaging, has made it possible to prognosticate severity of CDH and to stratify risk when counseling expectant parents. Risk stratification can also better prepare healthcare teams to enable optimal neonatal management, and provide options for fetal intervention or, where legally permitted, pregnancy termination. Factors that may affect the immediate and long-term prognosis for CDH include prenatal diagnosis, gestational age at detection and delivery, side of the defect, presence of additional structural or genetic abnormalities, defect size, estimation of fetal lung volume, the extent of visceral herniation, and the delivery center's experience in caring for neonates with CDH. Optimizing the outcome for families and infants begins with an early prenatal diagnosis followed by referral to a diverse and inclusive multidisciplinary center with CDH expertise. Prediction of disease severity is supported by accurate fetal imaging and comprehensive genetic testing, and allows the care team to provide realistic outcome expectations during the counseling of expectant parents of all racial and ethnic backgrounds.","PeriodicalId":23823,"journal":{"name":"World Journal of Pediatric Surgery","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hirschsprung-associated enterocolitis: a comprehensive review. 赫氏相关性小肠结肠炎：全面回顾。

IF 0.8 4区医学

World Journal of Pediatric Surgery Pub Date : 2024-10-14 eCollection Date: 2024-01-01 DOI: 10.1136/wjps-2024-000878

Ioannis A Ziogas, Korah P Kuruvilla, Ming Fu, Ankush Gosain

引用次数: 0

Numerical modeling assisting in surgical treatment of total anomalous pulmonary venous connection in children. 辅助儿童全异常肺静脉连接手术治疗的数值模型。

IF 0.8 4区医学

World Journal of Pediatric Surgery Pub Date : 2024-10-14 eCollection Date: 2024-01-01 DOI: 10.1136/wjps-2023-000741

Jie Jin, Kaiyun Gu, Jiawei Liang, Jing Yu, Xiangming Fan

{"title":"Numerical modeling assisting in surgical treatment of total anomalous pulmonary venous connection in children.","authors":"Jie Jin, Kaiyun Gu, Jiawei Liang, Jing Yu, Xiangming Fan","doi":"10.1136/wjps-2023-000741","DOIUrl":"https://doi.org/10.1136/wjps-2023-000741","url":null,"abstract":"Objective: To develop a model using patient-specific computational fluid dynamics (CFD) to predict the required anastomotic size for total anomalous pulmonary venous connection (TAPVC) surgery and to forecast surgical outcomes.Methods: Based on clinical data from patients, a CFD model was used to simulate the anastomosis between pulmonary venous confluence and the left atrium. Blood flow velocity, wall shear stress, power loss, and pressure were calculated using numerical algorithms within the model. Various sizes of anastomosis were applied during the simulation. The energy dissipation at the anastomosis was computed from the results and compared with real-world data.Results: As the simulated anastomotic size increased, blood flow velocity, pulmonary venous pressure, and energy loss decreased. However, when the anastomotic size exceeded 18 mm, the efficiency of energy conversion no longer improved. The realistic and simulated velocities matched well for anastomosis sizes ranging from 15 to 20 mm.Conclusion: The model can assist surgeons in preoperative planning for determining the anastomotic size in TAPVC surgical treatment.","PeriodicalId":23823,"journal":{"name":"World Journal of Pediatric Surgery","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term outcomes and quality of life in patients with Hirschsprung disease. 赫氏胃肠病患者的长期疗效和生活质量。

IF 0.8 4区医学

World Journal of Pediatric Surgery Pub Date : 2024-10-09 eCollection Date: 2024-01-01 DOI: 10.1136/wjps-2024-000859

Mikko P Pakarinen, Annika Mutanen

{"title":"Long-term outcomes and quality of life in patients with Hirschsprung disease.","authors":"Mikko P Pakarinen, Annika Mutanen","doi":"10.1136/wjps-2024-000859","DOIUrl":"https://doi.org/10.1136/wjps-2024-000859","url":null,"abstract":"Although patients with Hirschsprung disease are mostly affected by imperfect bowel function and fecal control in the long term, they are also predisposed to lower urinary tract symptoms, impaired sexual functions, infertility, psychosocial issues, and decreased quality of life. Rare, but notable comorbidities, which may manifest after childhood, include inflammatory bowel disease and familial medullary thyroid cancer. Despite frequent occurrence of fecal incontinence and constipation, the overall long-term outlook is quite optimistic as social continence with a good quality of life can be achieved by efficient bowel management also in those affected patients, whose self-coping strategies and medical treatment remain insufficient. Bowel dysfunction and other potential long-term complications are best managed by an interdisciplinary specialized approach not overlooking psychosocial issues, which also helps to correctly identify areas requiring continuing input by adult healthcare for young adult patients after transition. Additional research is needed to unravel the pathophysiological mechanisms of the long-term bowel dysfunction to identify novel therapeutic targets for development of more efficient innovative management strategies and thereby improvement of quality of life.","PeriodicalId":23823,"journal":{"name":"World Journal of Pediatric Surgery","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Controversies in Hirschsprung surgery. 赫氏脓肿手术的争议。

IF 0.8 4区医学

World Journal of Pediatric Surgery Pub Date : 2024-09-25 eCollection Date: 2024-01-01 DOI: 10.1136/wjps-2024-000887

Thomas O Xu, Marc A Levitt, Christina Feng

引用次数: 0

Top 100 most-cited articles on pediatric anesthesia from 1990 to 2023. 1990 年至 2023 年小儿麻醉方面被引用次数最多的 100 篇文章。

IF 0.8 4区医学

World Journal of Pediatric Surgery Pub Date : 2024-09-18 eCollection Date: 2024-01-01 DOI: 10.1136/wjps-2024-000823

Minyue Qian, Jia Zhong, Zhongteng Lu, Wenyuan Zhang, Kai Zhang, Yue Jin

{"title":"Top 100 most-cited articles on pediatric anesthesia from 1990 to 2023.","authors":"Minyue Qian, Jia Zhong, Zhongteng Lu, Wenyuan Zhang, Kai Zhang, Yue Jin","doi":"10.1136/wjps-2024-000823","DOIUrl":"https://doi.org/10.1136/wjps-2024-000823","url":null,"abstract":"Pediatric anesthesia presents greater challenges than does adult anesthesia. This bibliometric analysis aimed to analyze the top 100 most cited articles to be better understand the hot spots and prospects in pediatric anesthesia. Articles and reviews related to pediatric anesthesia were retrieved from the Web of Science Core Collection from 1990 to 2023. A bibliometric analysis of the top 100 most cited articles was also performed using information such as topics, author names, countries, institutions, publication years, and journals. A total of 32 831 articles were identified, with a total of 32 230 citations for the top 100 articles. The peak period for pediatric anesthesia research was from 2005 to 2009. The USA has emerged as the most active country in pediatric anesthesia research. Major journals published included Anesthesia and Analgesia, Anesthesiology, and Pediatrics, underscoring their authority in the field. Clinical studies on the top 100 most cited articles have focused on different stages of the perioperative period, the use of different anesthetic agents, and adverse outcomes in pediatric patients. The current study conducted a bibliometric analysis of the top 100 most cited articles in the field of pediatric anesthesia. Such insights are valuable for identifying research hot spots, assessing academic impact and collaboration in pediatric anesthesia, and guiding future research directions.","PeriodicalId":23823,"journal":{"name":"World Journal of Pediatric Surgery","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11428989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pullthrough pitfalls in treating Hirschsprung disease. 治疗赫氏胃肠病的牵引陷阱

IF 0.8 4区医学

World Journal of Pediatric Surgery Pub Date : 2024-09-13 DOI: 10.1136/wjps-2024-000862

Kristy L Rialon,Jacob C Langer

引用次数: 0

Hirschsprung disease: common and uncommon variants. 赫氏prung 病：常见和不常见变异。

IF 0.8 4区医学

World Journal of Pediatric Surgery Pub Date : 2024-08-28 eCollection Date: 2024-01-01 DOI: 10.1136/wjps-2024-000864

Lily S Cheng, Richard J Wood

引用次数: 0

Surgical management of the diaphragmatic defect in congenital diaphragmatic hernia: a contemporary review. 先天性膈疝膈肌缺损的手术治疗：当代综述。

IF 0.8 4区医学

World Journal of Pediatric Surgery Pub Date : 2024-08-21 eCollection Date: 2024-01-01 DOI: 10.1136/wjps-2023-000747

Marietta Jank, Michael Boettcher, Richard Keijzer

{"title":"Surgical management of the diaphragmatic defect in congenital diaphragmatic hernia: a contemporary review.","authors":"Marietta Jank, Michael Boettcher, Richard Keijzer","doi":"10.1136/wjps-2023-000747","DOIUrl":"10.1136/wjps-2023-000747","url":null,"abstract":"Worldwide, 150 children are born each day with congenital diaphragmatic hernia (CDH), a diaphragmatic defect with concomitant abnormal lung development. Patients with CDH with large defects are particularly challenging to treat, have the highest mortality, and are at significant risk of long-term complications. Advances in prenatal and neonatal treatments have improved survival in high-risk patients with CDH, but surgical treatment of large defects lacks standardization. Open repair by an abdominal approach has long been considered the traditional procedure, but the type of defect repair (patch or muscle flap) and patch material (non-absorbable, synthetic or absorbable, biological) remain subjects of debate. Increased experience and improved techniques in minimally invasive surgery (MIS) have expanded selection criteria for thoracoscopic defect repair in cardiopulmonary stable patients with small defects. However, the application of MIS to repair large defects remains controversial due to increased recurrence rates and unknown long-term effects of perioperative hypercapnia and acidosis resulting from capnothorax and reduced ventilation. Current recommendations on the surgical management rely on cohort studies of varying patient numbers and data on the long-term outcomes are sparse. Here, we discuss surgical approaches for diaphragmatic defect repair highlighting advancements, and knowledge gaps in surgical techniques (open surgery and MIS), patch materials and muscle flaps for large defects, as well as procedural adjuncts and management of CDH variants.","PeriodicalId":23823,"journal":{"name":"World Journal of Pediatric Surgery","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11340723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142056684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of genetics and the environment in the etiology of congenital diaphragmatic hernia. 遗传和环境在先天性膈疝病因中的作用。

IF 0.8 4区医学

World Journal of Pediatric Surgery Pub Date : 2024-08-21 eCollection Date: 2024-01-01 DOI: 10.1136/wjps-2024-000884

Siyuan Liu, Lan Yu

{"title":"Role of genetics and the environment in the etiology of congenital diaphragmatic hernia.","authors":"Siyuan Liu, Lan Yu","doi":"10.1136/wjps-2024-000884","DOIUrl":"10.1136/wjps-2024-000884","url":null,"abstract":"Congenital diaphragmatic hernia (CDH) is a congenital malformation characterized by failure of diaphragm closure during embryonic development, leading to pulmonary hypoplasia and pulmonary hypertension, which contribute significantly to morbidity and mortality. The occurrence of CDH and pulmonary hypoplasia is theorized to result from both abnormalities in signaling pathways of smooth muscle cells in pleuroperitoneal folds and mechanical compression by abdominal organs within the chest cavity on the developing lungs. Although, the precise etiology of diaphragm maldevelopment in CDH is not fully understood, it is believed that interplay between genes and the environment contributes to its onset. Approximately 30% of patients with CDH possess chromosomal or single gene defects and these patients tend to have inferior outcomes compared with those without genetic associations. At present, approximately 150 gene variants have been linked to the occurrence of CDH. The variable expression of the CDH phenotype in the presence of a recognized genetic predisposition can be explained by an environmental effect on gene penetrance and expression. The retinoic acid pathway is thought to play an essential role in the interactions of genes and environment in CDH. However, apart from the gradually maturing retinol hypothesis, there is limited evidence implicating other environmental factors in CDH occurrence. This review aims to describe the pathogenesis of CDH by summarizing the genetic defects and potential environmental influences on CDH development.","PeriodicalId":23823,"journal":{"name":"World Journal of Pediatric Surgery","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11340715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142056683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0