World journal of pharmaceutical research最新文献_第10页

SPECTROSCOPIC EVIDENCE FOR STERIC ENHANCEMENT OF RESONANCE IN RHODIUM (III) CHLORIDE COMPLEXES 氯化铑配合物中共振立体增强的光谱证据

World journal of pharmaceutical research Pub Date : 2017-10-01 DOI: 10.20959/wjpr201710-9393

M. Sreenivasarao

{"title":"SPECTROSCOPIC EVIDENCE FOR STERIC ENHANCEMENT OF RESONANCE IN RHODIUM (III) CHLORIDE COMPLEXES","authors":"M. Sreenivasarao","doi":"10.20959/wjpr201710-9393","DOIUrl":"https://doi.org/10.20959/wjpr201710-9393","url":null,"abstract":"The assignments reveal that the carboxyl substituted complexes are isolated as facisomers and all the remaining seven complexes are having mer-octahedral configuration. Using these sulphides as ligands Rhodium (III) chloride complexes have been synthesized and analyzed. The infrared spectra of these complexes have been recorded in the region 600– 200 cm -1 . Generally the electron releasing group in Benzene ring decreases the v(Rh-S) stretching frequency value from the present one where as the electron withdrawing group increases the v(Rh-S) stretching frequency value form its parent one. Otherwise the electron donor exerts a weakening effect on the Rh-S band and the electron acceptor removes from the metal. The appearance of –OH bond in the complexes of carboxylic substituted ligands shows the absence of intra molecular hydrogen bonding between –OH of carboxylic group and chlorine. The carboxyl frequency of meta and para carboxylic groups gets increased when compared with the ligands. But in the case of higher stability of the meta and para isomers. In recording the electronic spectra the same solvent was used both for the complex and ligand. Generally the bathochromic shift is observed when there is an electron releasing group present in the benzene ring and the presence of electron withdrawing group or steric inhibition results in a hypsochromic shift. The complexes involving p-NO2 and p-COOH substituted phenyl methyl sulphides have the absorption bands almost identical with those of ligands. When an electron donor is present in World Journal of Pharmaceutical Research SJIF Impact Factor 7.523 Volume 6, Issue 10, 901-923. Research Article ISSN 2277– 7105 Article Received on 10 July 2017, Revised on 30 July 2017, Accepted on 20 Aug 2017 DOI: 10.20959/wjpr201710-9393 *Corresponding Author","PeriodicalId":23796,"journal":{"name":"World journal of pharmaceutical research","volume":"127 1","pages":"901-923"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77387820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DEVELOPMENT AND VALIDATION OF ARTEMETHER & LUMEFANTRINE IN PHARMACEUTICAL DOSAGE FORMS 药物剂型蒿甲醚和甲苯曲明的开发与验证

World journal of pharmaceutical research Pub Date : 2017-10-01 DOI: 10.20959/wjpr201710-9352

A. Rajesh

{"title":"DEVELOPMENT AND VALIDATION OF ARTEMETHER & LUMEFANTRINE IN PHARMACEUTICAL DOSAGE FORMS","authors":"A. Rajesh","doi":"10.20959/wjpr201710-9352","DOIUrl":"https://doi.org/10.20959/wjpr201710-9352","url":null,"abstract":"The developed method was validated for parameters such as System suitability, Precision, Accuracy, Linearity and Robustness for the assay of Artemether + Lumefantrine. Hence the method is suitable, linear, precise, accurate and robust for the assay of Artemether and Lumefantrine. Precision and Accuracy are the major control parameters of the whole validation procedure were within the acceptable limits. The experimental data makes a relevant contribution to the understanding of validation parameters.The present work shows a validated, highly sensitive and selective method for determination of Artemether (20mg) + Lumefantrine (120mg) in tablet dosage forms. Key Word: Precision , Validation, Dosage Forms INTRODUCTION Chromatography is a technique by which the components in a sample, carried by the liquid or gaseous phase, are resolved by sorption-desorption steps on the stati onary phase. [1-3] HPLC is a type of liquid chromatography that employs a liquid mobile phase and a very finely divided stationary phase. In order to obtain satisfactory flow rate liquid must be pressurized to a few thousands of pounds per square inch. The HPLC is the method of choice in the field of analytical chemistry, since this method is specific, robust, linear, precise and accurate and the limit of detection is low and also it offers the following advantages.Speed (many analysis can be accomplished in 20 min or less), Greater sensitivity (various detectors can be employed) Improved resolution (wide variety of stationary phases), Reusable columns (expensive columns but can be used for many analysis), Ideal for the substances of low viscosity, Easy sample recovery, handling and maintenance. Instrumentation leads itself to World Journal of Pharmaceutical Research SJIF Impact Factor 7.523 Volume 6, Issue 10, 749-767. Research Article ISSN 2277– 7105 *Corresponding Author Dr. A. Rajesh Hindu College of Pharmacy, Guntur-522 002. Article Received on 09 July 2017, Revised on 29 July 2017, Accepted on 19 August 2017 DOI: 10.20959/wjpr201710-9352","PeriodicalId":23796,"journal":{"name":"World journal of pharmaceutical research","volume":"603 1","pages":"749-767"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77609955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PHARMACOGNOSTIC AND DRUG EVALUATION PARAMETERS OF PINUS ROXBURGHII SARG 刺梨松生药学及药物评价参数

World journal of pharmaceutical research Pub Date : 2017-10-01 DOI: 10.20959/wjpr201710-9564

N. Kumari

{"title":"PHARMACOGNOSTIC AND DRUG EVALUATION PARAMETERS OF PINUS ROXBURGHII SARG","authors":"N. Kumari","doi":"10.20959/wjpr201710-9564","DOIUrl":"https://doi.org/10.20959/wjpr201710-9564","url":null,"abstract":"The Pinus roxburghii Sarg (Pinaceae) is commonly known as chir pine. It is a large tree up to 28-55 m in height. The bark is red-brown, leaves are needle-like, in fascicles of three, very slender, distinctly yellowish green. The P.roxburghii is an economically valuable species, balancing the ecosystem of the Indian mountains. The plant have their own pharmaceutically importance. In traditional system of medicine different parts of the plant have been used for cough, cold, influenza, tuberculosis, bronchitis antiseptic, diaphoretic, diuretic, rubefacient, stimulant and vermifuge. Bark paste is used in burns. Resin is used to relieve cough and gastric troubles. Plant is used as intestinal antiseptic, hypolipidimic, antioxidant property. The present study was undertaken to assess pharmacognostic parameters and phytochemical screnning of bark of Pinus roxburghii Sarg. Organoleptic evaluation of bark were done by studying organoleptic features like shape, size,colour, odour, taste and fracture In microscopy the bark was soaking into water filled beaker so that sufficient moistening is obtained for microscopy. In powder microcsopy dried powdered material was obtained by grinding bark and visual under microscope taken at 100x .To evaluate the Physico chemical property the crude dried plant material was subjected to study the various parameters such as extractive value using different solvent pet ether, chloroform, methanol and water, also calculate the percentage yield of moisture content, ash value including acid insoluble, water soluble ash, fluorescence analysis and loss on drying etc were evaluated by using standard procedures. To evaluate the phytochemical screening of extracts the different solvents were used such as Sodium hydroxide, Chloral hydrate, Ferric chloride, Sulphuric acid, Iodine, Lead acetate, Magnesium, World Journal of Pharmaceutical Research SJIF Impact Factor 7.523 Volume 6, Issue 10, 1756-1770. Research Article ISSN 2277– 7105 *Corresponding Author","PeriodicalId":23796,"journal":{"name":"World journal of pharmaceutical research","volume":"5 1","pages":"1756-1770"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80157543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

GARBHINI PARICHARYA: FOR BETTER DEVELOPMENT OF PROGENY Garbhini paricharya:为了后代更好的发展

World journal of pharmaceutical research Pub Date : 2017-10-01 DOI: 10.20959/WJPR201710-9423

H. Kumar

引用次数: 0

IMPACT OF CONTRACEPTIVE USE UPON WOMEN’S HEALTH STATUS ATTENDING HEALTH FAMILY PLANNING CENTERS IN KUT CITY 使用避孕药具对库特市保健计划生育中心妇女健康状况的影响

World journal of pharmaceutical research Pub Date : 2017-10-01 DOI: 10.20959/WJPR201710-9248

Rasha M. Jumaa

{"title":"IMPACT OF CONTRACEPTIVE USE UPON WOMEN’S HEALTH STATUS ATTENDING HEALTH FAMILY PLANNING CENTERS IN KUT CITY","authors":"Rasha M. Jumaa","doi":"10.20959/WJPR201710-9248","DOIUrl":"https://doi.org/10.20959/WJPR201710-9248","url":null,"abstract":"Background: Contraceptives have been widely used since the mid19th century for a reason including the prevention of unwanted pregnancy. In family planning (FP), contraception is the main component of health services and it is beneficial to the health and wellbeing of women, men, children and families And their communities. Objective To identify the effect of using of contraception on physical, psychological and social women health,. Subject and methods: A cross-sectional study on impact of contraceptive methods use was conducted among women collected using structured and in-depth interview questionnaires. Information gathered included four dominoes socio-demographic characteristics, reproductive information and medical health history, information on the use of contraception method and impact of contraception method on women's health (physical, psychological and social impact) done at health centers in kut city. The study conducted from1st December 2016 to 28 February 2017, The sample size was (238) women attainting to family planning units. Results It was found that (20-24) years the age at marriage were (42.0%), (1924%) were getting the first pregnancy (56.3%), 13 of the sample were gravida (34) and (60.5%) of the sample using contraception pills. the purpose of using contraception was mostly to reduce number of children (49.8%), according to physical impact of contraception it was found that fatigue show high assessment. The others were between moderate to low, regarding to psychological impact of contraception it was found positive impact in the patient with high assessment. And in social impact it was showed moderate assessment in both factors. World Journal of Pharmaceutical Research SJIF Impact Factor 7.523 Volume 6, Issue 10, 13-26. Research Article ISSN 2277– 7105 *Corresponding Author Rasha M. Jumaa Community Health Specialist. Article Received on 07 July 2017, Revised on 27 July 2017, Accepted on 17 August 2017 DOI: 10.20959/wjpr201710-9248","PeriodicalId":23796,"journal":{"name":"World journal of pharmaceutical research","volume":"33 1","pages":"13-26"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85687663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EFFICACY OF SIDDHA MEDICINE AND VARMAM THERAPY IN PAKKA VATHAM (HEMIPLEGIA) - A SINGLE CASE STUDY 悉达药物和瓦曼疗法在pakka vatham(偏瘫)中的疗效——一个个案研究

World journal of pharmaceutical research Pub Date : 2017-10-01 DOI: 10.20959/wjpr201710-9398

G. Pratheep

引用次数: 0

AM1 STUDY ON THE CONFORMATIONS OF ZWITTERIONS OF BENZYLPENICILLIN LACTIM TAUTOMER 青霉素乳酸互变异构体两性离子构象的研究

World journal of pharmaceutical research Pub Date : 2017-10-01 DOI: 10.20959/WJPR201710-9386

B. Rao

引用次数: 0

ASSESSING THE KNOWLEDGE ON SELF-MEDICATION AMONG MEDICAL STUDENTS OF BANGLADESH 评估孟加拉国医科学生关于自我药疗的知识

World journal of pharmaceutical research Pub Date : 2017-10-01 DOI: 10.20959/wjpr201710-8914

O. Pavel

引用次数: 2

TAXONOMICAL STUDY OF ACACIA NILOTICA (LINN) WILD (A DYE YIELDING PLANT) IN CHURU DISTRICT 楚鲁地区产染料植物野生金合欢的分类研究

World journal of pharmaceutical research Pub Date : 2017-10-01 DOI: 10.20959/WJPR201710-9408

R. Verma

引用次数: 2

PHARMACOGNOSTICSTUDIES OF EUPHORBIA HIRTA L.

World journal of pharmaceutical research Pub Date : 2017-10-01 DOI: 10.20959/wjpr201710-9421

M. Vaidya

引用次数: 1