Yonago acta medica最新文献

{"title":"Factors Affecting the Device Life of Voice Prosthesis in Laryngectomized Patients.","authors":"Kenkichiro Taira, Takahiro Fukuhara, Hideyuki Kataoka, Satoshi Koyama, Ryohei Donishi, Kazunori Fujiwara","doi":"10.33160/yam.2026.02.008","DOIUrl":"10.33160/yam.2026.02.008","url":null,"abstract":"<p><strong>Background: </strong>Voice restoration with a voice prosthesis has recently become popular among laryngectomized patients due to good voice quality and functional outcomes. An important limitation, however, is the need to periodically replace these devices. Factors affecting prosthesis lifespan differ between countries and regions. We assessed determinants of replacement frequency in Japan.</p><p><strong>Methods: </strong>This retrospective, observational study included 45 patients who opted to receive a voice prosthesis after total laryngectomy. Twenty-one patients were excluded, and thus 24 were analyzed. We defined 3 types of factors affecting voice prosthesis replacement: tracheal site factors, esophageal site factors, and types of prostheses. The association of each factor with device lifespan was examined using the Mann-Whitney <i>U</i> test and Kruskal-Wallis test.</p><p><strong>Results: </strong>Twenty-four patients consented to this study and were surveyed about device lifespan. Twenty-one male patients and three female patients underwent voice prosthesis insertion for secondary voice restoration after total laryngectomy. The mean duration before replacement was 85 ± 36 (range 14-434) days. Total follow-up duration and tracheal dryness were both significantly associated with device lifespan.</p><p><strong>Conclusion: </strong>Learning to properly manage the VP over time and preventing tracheal dryness are required to prolong voice prosthesis lifespan in Japan.</p>","PeriodicalId":23795,"journal":{"name":"Yonago acta medica","volume":"69 1","pages":"71-77"},"PeriodicalIF":1.0,"publicationDate":"2026-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12910231/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Study of Complications Associated with Mandibular Reconstruction Plates Used in Resection of Oral Squamous Cell Carcinoma.","authors":"Takayuki Tamura, Yusei Harada, Kento Ikuta, Yoshiko Suyama, Takayuki Shingu, Yuki Harada, Kousuke Sakai, Kousuke Amatsu, Kiharu Shimizu, Takashi Narai, Shunjiro Yagi, Isamu Kodani","doi":"10.33160/yam.2026.02.018","DOIUrl":"10.33160/yam.2026.02.018","url":null,"abstract":"<p><strong>Background: </strong>Reconstructive plates used in mandibular reconstruction may lead to complications such as plate fracture or exposure, and their management is often difficult. In this study, we investigated complications associated with mandibular reconstruction plates in patients who underwent resection of oral squamous cell carcinoma in our department.</p><p><strong>Methods: </strong>Twenty-five patients who received mandibular reconstruction plates during oral squamous cell carcinoma resection at our department over approximately the past 10 years were reviewed. Parameters examined included age, sex, tumor location, stage, type and timing of complication, possible causes, and treatments.</p><p><strong>Results: </strong>Plate exposure occurred in 4 patients, and plate fracture occurred in 4 patients. All exposures were on the cutaneous side. Additional findings included screw fractures and bone resorption around screws. Plate fractures tended to occur more often in patients with strong occlusal support. Patients without reconstruction showed a significantly higher incidence of fracture. Plate fracture was also influenced by plate configuration and bending, while plate exposure was attributed mainly to insufficient soft tissue volume.</p><p><strong>Conclusion: </strong>Although plate reconstruction is useful, the relatively high frequency of complications requires careful consideration of multiple factors when determining its application.</p>","PeriodicalId":23795,"journal":{"name":"Yonago acta medica","volume":"69 1","pages":"125-130"},"PeriodicalIF":1.0,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12910219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146220532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Questionnaire Survey on Human Papillomavirus Vaccination Among Hospital-Based Healthcare Professionals.","authors":"Ayami Kimura, Tetsuro Oishi, Rina Fujioka, Wakae Tashiro, Masakuni Takahashi, Junzo Kigawa, Takashi Irie","doi":"10.33160/yam.2026.02.016","DOIUrl":"10.33160/yam.2026.02.016","url":null,"abstract":"<p><strong>Background: </strong>Although active human papillomavirus (HPV) vaccination recommendations resumed in Japan in 2022, vaccination rates remain low. Understanding hospital staff attitudes toward HPV vaccination may provide insights into improving vaccine uptake.</p><p><strong>Methods: </strong>An anonymous Google Form survey was conducted among Matsue City Hospital staff in August 2024. The questionnaire addressed knowledge and perceptions of cervical cancer and HPV vaccines, vaccination history, and future vaccination intentions. Respondents were classified as proactive or passive based on their family's vaccination intentions. Statistical analysis was performed using Fisher's exact test, with <i>P</i> < 0.05 considered significant.</p><p><strong>Results: </strong>Responses were received from 154 participants (response rate: 23.6%), with 88.3% of participants aged ≥ 27 years. While 89.0% and 82.4% reported being \"well aware\" or \"aware\" of cervical cancer and HPV vaccines, respectively, 40.3% were passive about family vaccination, and 36.4% expressed safety concerns. Acceptance of vaccine efficacy was significantly higher in the proactive group than in the passive group (96.7% vs. 59.7%, <i>P</i> < 0.0001). Safety concerns were significantly lower in the proactive group than in the passive group (25.0% vs. 56.5%; <i>P</i> < 0.0001). Knowledge was associated with understanding of efficacy (85.0% vs. 66.7%, <i>P</i> = 0.0502) but not with safety concerns (36.2% vs. 44.4%, <i>P</i> = 0.5126).</p><p><strong>Conclusion: </strong>Approximately 40% of healthcare workers exhibited passive attitudes toward vaccination, and safety concerns significantly influenced their intentions. Improving accurate knowledge dissemination and addressing negative safety perceptions among hospital staff are crucial for increasing vaccination rates.</p>","PeriodicalId":23795,"journal":{"name":"Yonago acta medica","volume":"69 1","pages":"119-124"},"PeriodicalIF":1.0,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12910230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Preserving the Collateral Arterial Arcade in the Head of the Pancreas in a Patient with Celiac Axis Stenosis.","authors":"Mikiya Kishino, Teruhisa Sakamoto, Shinsaku Yata, Kentaro Uehira, Jun Yoshida, Masaki Morimoto, Yuki Murakami, Naruo Tokuyasu, Yoshiyuki Fujiwara","doi":"10.33160/yam.2026.02.017","DOIUrl":"10.33160/yam.2026.02.017","url":null,"abstract":"<p><p>An 80-year-old man with middle-third cholangiocarcinoma associated with celiac axis stenosis underwent pancreaticoduodenectomy. During surgery, the anterior arcade that had developed in the pancreatic head as a collateral pathway between the superior mesenteric artery and the hepatic artery was preserved as a collateral route to ensure adequate hepatic and gastric perfusion. This may be a useful option for pancreaticoduodenectomy in a patient with celiac axis stenosis.</p>","PeriodicalId":23795,"journal":{"name":"Yonago acta medica","volume":"69 1","pages":"136-138"},"PeriodicalIF":1.0,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12910218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cultivating Empathy through Visual Thinking Strategy Workshops for Medical Students and Residents: A Mixed-Methods Study.","authors":"Daisuke Son, Minako Kamimoto, Kazuoki Inoue, Shin-Ichi Taniguchi","doi":"10.33160/yam.2026.02.013","DOIUrl":"10.33160/yam.2026.02.013","url":null,"abstract":"<p><p>Visual Thinking Strategy (VTS) has been introduced in health professions education as a method for enhancing observational skills, empathy, and communication through group dialogue around artworks. This study explored how VTS workshops might cultivate empathy and related competencies among Japanese medical students and residents. Six participants (three medical students and three family medicine residents) attended eight workshops facilitated by a trained VTS instructor between November and December 2021. Sessions were held four times online and four times in person, using artworks and public sculptures as stimuli. Empathy was assessed before and after the series using the Japanese versions of the Jefferson Scale of Empathy (JSE) and the Interpersonal Reactivity Index (IRI). Participants' reflective writings were analyzed thematically. Quantitatively, mean IRI scores increased from 94.0 to 99.3 (Cohen's <i>d</i> = 0.37), and mean JSE scores increased from 109.3 to 111.7 (Cohen's <i>d</i> = 0.20). Qualitative analysis revealed six thematic categories: clinical observation, empathy/perspective-taking, communication, cultural sensitivity, tolerance for diversity, and self-awareness. These findings suggest that VTS-based workshops may enhance empathy through perspective-taking, tolerance of diverse interpretations, and reflection on one's own biases. Incorporating art-based dialogue in medical education could complement conventional communication training by promoting humanistic awareness in future physicians.</p>","PeriodicalId":23795,"journal":{"name":"Yonago acta medica","volume":"69 1","pages":"139-144"},"PeriodicalIF":1.0,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12910221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146220540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Appropriate Use of Antibiotics for Acute Respiratory Tract Infections in a Community Hospital in Rural Japan: A Medical Record-Based Study.","authors":"Kazuoki Inoue, Daeho Park, Toshihiro Hamada, Daisuke Son, Young Lee, Shintaro Imaoka, Tsubasa Nakai, Shohei Taniguchi, Minako Kamimoto, Masahiko Koda, Shin-Ichi Taniguchi","doi":"10.33160/yam.2026.02.007","DOIUrl":"10.33160/yam.2026.02.007","url":null,"abstract":"<p><strong>Background: </strong>Inappropriate antibiotic prescribing remains a global concern, as it contributes to adverse drug reactions, increased healthcare costs, and the spread of antimicrobial resistance. In Japan, several studies have investigated antibiotic prescription patterns; however, most rely solely on insurance claims data, which may not accurately reflect clinical diagnoses. This study aimed to evaluate the appropriateness of antibiotic use for acute respiratory tract infections (ARTIs) by cross-referencing disease names recorded in insurance claims with diagnoses documented in electronic medical records.</p><p><strong>Methods: </strong>We conducted a retrospective review of outpatient records from Hino Hospital, a community-based general hospital providing primary care services, between April 1, 2017, and March 31, 2018. Patients diagnosed with ARTIs were identified through claims data, and their diagnoses were confirmed using their medical records. The appropriateness of antibiotic prescriptions was assessed based on the Japanese clinical guideline, <i>Manual for Appropriate Antimicrobial Use</i>.</p><p><strong>Results: </strong>A total of 485 patients were included. The overall antibiotic prescription rate for ARTIs was 17.1%, and among those prescribed antibiotics, only 14.5% were deemed appropriate. The general medicine department had the lowest prescription rate and the highest rate of appropriate use among all departments.</p><p><strong>Conclusion: </strong>This study provides a chart-based analysis of inappropriate antibiotic use for ARTIs in Japan. To reduce inappropriate antibiotic prescriptions, multifaceted interventions and continuous evaluation will be necessary.</p>","PeriodicalId":23795,"journal":{"name":"Yonago acta medica","volume":"69 1","pages":"63-70"},"PeriodicalIF":1.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12910233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fostering Reflective Practice Through Participant Observation: Medical Students' Learning During Community-Based Clinical Training in Japan.","authors":"Minako Kamimoto, Daisuke Son, Kazuoki Inoue, Shintaro Imaoka, Tsubasa Nakai, Yuma Otsuka, Shohei Taniguchi, Shin-Ichi Taniguchi","doi":"10.33160/yam.2026.02.011","DOIUrl":"10.33160/yam.2026.02.011","url":null,"abstract":"<p><strong>Background: </strong>Since 2011, the Department of Community Medicine at Tottori University has provided community-based clinical training for fourth-year medical students. However, conventional community-based training often remains observational and does not necessarily foster students' critical reflection or active questioning in clinical settings. To address this gap, ethnographic methods from medical anthropology were introduced in 2018, allowing students to engage in participant observation. After each weekly practicum session conducted at a community-based medical facility, students documented the questions that emerged and their reasoning in an electronic portfolio (ePF), receiving individual feedback from faculty.</p><p><strong>Methods: </strong>A qualitative descriptive study was conducted using text data from the 2019 ePF entries of 107 fourth-year medical students. Descriptions of participant observation were analyzed using the text-mining software KH Coder. Co-occurrence network diagrams and textual analysis were used to extract thematic categories.</p><p><strong>Results: </strong>Frequently used words included <i>\"observe,\" \"think,\" \"learn,\"</i> and <i>\"feel.\"</i> Cluster analysis revealed strong associations such as <i>\"question\"</i> with <i>\"have,\" \"university\"</i> with <i>\"community,\"</i> and <i>\"study\"</i> with <i>\"knowledge.\"</i> Students commonly formulated action plans emphasizing active observation and critical questioning for future clinical training.</p><p><strong>Conclusion: </strong>Participant observation enabled students to reflect on differences between community and university-based clinical settings. The exercise promoted the development of critical thinking and multiple perspectives, suggesting the value of incorporating anthropological methods into pre-clinical medical education.</p>","PeriodicalId":23795,"journal":{"name":"Yonago acta medica","volume":"69 1","pages":"95-104"},"PeriodicalIF":1.0,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12910223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rice Bran Attenuates Liver Fibrosis Caused by Vitamin E Deficiency in the Pre-Aging Stage.","authors":"Yoichi Takahashi, Yugo Kato, Yosuke Horikoshi, Takehiko Hanaki, Masaru Ueki, Kazuhiro Nakaso","doi":"10.33160/yam.2026.02.014","DOIUrl":"10.33160/yam.2026.02.014","url":null,"abstract":"<p><p>Vitamin E (VE) is a fat-soluble vitamin and well-known as an antioxidant. VE deficiency is associated with various oxidative stress- and aging-related pathologies and sufficient VE intake is thought to help prevent these conditions. However, it has been unclear how VE deficiency in the pre-aging stage affects the liver. In the present study, 11-month-old mice were fed a VE-restricted diet for 3 months, when age-related changes began to appear, to examine the effects of VE deficiency on the liver. Compared to the livers of mice fed a standard diet, those fed a VE-deficient diet showed metabolic dysfunction-associated steatohepatitis (MASH)-like findings including fibrosis. Mice fed the VE-deficient diet mixed with 2% rice bran (RB) showed milder fibrosis than those fed the VE-deficient diet alone. These results suggest that VE deficiency in the pre-aging stage may cause MASH-like changes in the liver, particularly fibrosis, and that RB is an effective means of supplying VE.</p>","PeriodicalId":23795,"journal":{"name":"Yonago acta medica","volume":"69 1","pages":"145-148"},"PeriodicalIF":1.0,"publicationDate":"2026-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12910222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Near-End-of-Life Trajectory in Patients with Advanced Lung Cancer.","authors":"Naoki Kinoshita, Mitsuhiro Yamamoto, Tomoyuki Ikeuchi, Hirokazu Touge, Katsuyuki Tomita, Akira Yamasaki","doi":"10.33160/yam.2026.02.009","DOIUrl":"10.33160/yam.2026.02.009","url":null,"abstract":"<p><strong>Background: </strong>Performance status is a useful prognostic index in palliative care. The objectives of this study were to investigate the prognosis of near-end-of-life patients with advanced lung cancer admitted due to deteriorated performance status, evaluate the utility of performance status measurement in predicting life expectancy, and identify prognostic factors using Bayesian proportional hazards models.</p><p><strong>Methods: </strong>This prospective observational cohort study measured at admission, the Performance status, Palliative Performance Scale, Karnofsky Performance Status (KPS), Palliative Prognostic Index scores, and clinical biochemistry parameters of the included patients. Ninety-two patients with advanced lung cancer and deteriorated performance status admitted to our department at the NHO Yonago Medical Center between January 2016 and December 2018 were analyzed. Bayesian proportional hazards models were employed to classify remaining life prognoses. The Watanabe-Akaike information criteria (WAIC) with the lowest score was used to choose the final model.</p><p><strong>Results: </strong>The median survival time was 25 (range, 1-107) days. The final prognostic model for the dying trajectory of patients was selected as an M-spline proportional hazards model according to the least WAIC. Independent prognostic factors for shorter remaining life were hypercalcinemia [hazard ratio (HR) 5.37, 95% confidence interval (CI) 2.11-12.9] and low KPS (HR 1.77, 95%CI 1.30-2.46).</p><p><strong>Conclusion: </strong>Assessing hypercalcinemia and KPS can be advantageous for predicting near-end-of-life prognosis in terminally ill patients with advanced lung cancer.</p>","PeriodicalId":23795,"journal":{"name":"Yonago acta medica","volume":"69 1","pages":"78-87"},"PeriodicalIF":1.0,"publicationDate":"2026-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12910232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Underweight Status and Social Jet Lag Among Japanese University Students: A Cross-Sectional Study with Sex-Specific Analysis.","authors":"Shinobu Sugihara, Ryo Miyazaki, Masahiko Kato","doi":"10.33160/yam.2026.02.006","DOIUrl":"10.33160/yam.2026.02.006","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of underweight among young adults in Japan is approximately 20% in both males and females. Despite its potential health risks, underweight in males has received limited attention. Social jet lag (SJL), the misalignment between biological and social time, has recently been associated with various health outcomes, including obesity and circadian rhythm disturbance. However, evidence on the relationship between SJL and underweight, particularly regarding gender differences, remains limited. This study aimed to examine the association between SJL, lifestyle factors including internet use, and underweight status among university students, focusing on sex-specific differences.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 3,102 students (54.6% male) at Shimane University in 2022. Participants were classified into underweight (< 18.5 kg/m²) and non-underweight groups. Lifestyle data, including sleep patterns, diet, physical activity (PA), internet use, and gaming time, were obtained from health examinations and questionnaires. SJL was calculated as the difference in sleep midpoint between weekdays and weekends.</p><p><p>For multivariate analysis, logistic regression was performed with underweight as the dependent variable. Age was included as a covariate, and variables significant in univariate analyses were entered into sex-stratified models.</p><p><strong>Results: </strong>The prevalence of underweight was similar in males and females (17.2% vs. 17.3%). In both sexes, underweight students exhibited lower systolic blood pressure, higher resting heart rate, and lower PA than their non-underweight counterparts. Among males, the underweight group exhibited a greater median SJL (1h) and a higher prevalence of internet addiction (17.1%). Multivariate analysis revealed that SJL was independently associated with underweight only in males (OR = 1.14, <i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Although underweight university students exhibited similar physiological characteristics across sexes, SJL was independently associated with underweight only in males, suggesting that irregular sleep-wake patterns may constitute a novel behavioral risk factor for underweight in this population.</p>","PeriodicalId":23795,"journal":{"name":"Yonago acta medica","volume":"69 1","pages":"55-62"},"PeriodicalIF":1.0,"publicationDate":"2026-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12910224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}