World Journal of Traditional Chinese Medicine最新文献_第8页

The use of goal attainment scaling in the acupuncture of children with intellectual disability 目标实现量表在智障儿童针刺治疗中的应用

IF 4.4 3区医学

World Journal of Traditional Chinese Medicine Pub Date : 2022-10-01 DOI: 10.4103/2311-8571.351509

Siqi Zhang, Dong Lin, Lili Lin, Shi Qi, Meng Gong, Shi Li, Jie Zhang

{"title":"The use of goal attainment scaling in the acupuncture of children with intellectual disability","authors":"Siqi Zhang, Dong Lin, Lili Lin, Shi Qi, Meng Gong, Shi Li, Jie Zhang","doi":"10.4103/2311-8571.351509","DOIUrl":"https://doi.org/10.4103/2311-8571.351509","url":null,"abstract":"Objective: The therapeutic effect of acupuncture is often evaluated based on the experience and judgment of acupuncturists and the subjective feelings of patients. Thus, we investigated the suitability of goal attainment scaling (GAS), an objective outcome measurements, to evaluate the responsiveness of children with intellectual disability to acupuncture therapy. Methods: This is an assessor-blinded, single-group cohort study that included 17 children with intellectual disabilities. The therapeutic effect of acupuncture was assessed by the T scores of GAS at four time points during the 3-month treatment. The responsiveness of GAS to acupuncture therapy was measured using the standardized response mean (SRM). Results: Compared with control, the 4-, 8-, and 12-week scores improved significantly after treatment (P < 0.01, P ≤ 0.001, P ≤ 0.001), with significant differences between each month (P < 0.01, P ≤ 0.001, P ≤ 0.001). Furthermore, all periods assessed GAS (to measure the therapeutic effect of acupuncture) showed marked responsiveness (SRMs >0.8). Conclusion: GAS is responsive in evaluating individual changes in the acupuncture treatment of children with intellectual disabilities. It is a feasible tool to match both the needs of children with intellectual disabilities and the clinical characteristics of acupuncture.","PeriodicalId":23692,"journal":{"name":"World Journal of Traditional Chinese Medicine","volume":"8 1","pages":"522 - 529"},"PeriodicalIF":4.4,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48025957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

International Clinical Practice Guideline of Chinese Medicine-Age-related Macular Degeneration 《老年黄斑变性国际中医临床实践指南》

IF 4.4 3区医学

World Journal of Traditional Chinese Medicine Pub Date : 2022-10-01 DOI: 10.4103/2311-8571.353119

Xingzhi Wu, Lixin Xie, Lina Liang

引用次数: 2

Metabolic characterization of the Badagan constitution in mongolian medicine by ultrahigh-performance liquid chromatography/quadrupole time-of-flight mass spectrometry/MS 超高效液相色谱/四极杆飞行时间质谱/质谱联用技术对蒙药中巴达干组分代谢特性的研究

IF 4.4 3区医学

World Journal of Traditional Chinese Medicine Pub Date : 2022-10-01 DOI: 10.4103/2311-8571.351507

Xiao-hua Bao, Lina Bao, Chun Xiang, Siqin Gerile, Saihan Qiqige, Yuheng Xie

{"title":"Metabolic characterization of the Badagan constitution in mongolian medicine by ultrahigh-performance liquid chromatography/quadrupole time-of-flight mass spectrometry/MS","authors":"Xiao-hua Bao, Lina Bao, Chun Xiang, Siqin Gerile, Saihan Qiqige, Yuheng Xie","doi":"10.4103/2311-8571.351507","DOIUrl":"https://doi.org/10.4103/2311-8571.351507","url":null,"abstract":"This study aimed to identify the potential metabolic biomarkers of the Badagan constitution (BC) in Mongolian medicine. Serum samples from the participants with BCs (n = 32) and aggregative constitutions (n = 30) were analyzed by using ultrahigh-performance liquid chromatography/mass spectrometry. Meanwhile, principal component analysis and orthogonal partial least squares discriminant analysis were used to characterize the endogenous metabolites and potential biomarkers, respectively. Fifteen of the 18 biomarkers in six metabolic pathways were significantly upregulated, including phosphatidylserine, sphingolipids, tryptophan, riboflavin and glutathione, and three biomarkers were significantly downregulated, including lysophosphatidylcholine (LysoPC) (18:1), LysoPC (16:1), and lysophosphatidylethanolamine (LysoPE) (22:2). This study also implied that sphingolipid metabolism, glycerophospholipid metabolism, and tryptophan metabolism played important roles in the BC. Therefore, metabolomics may improve the diagnostic efficacy of the BC in terms of the accuracy and comprehensiveness of a diagnosis based on this constitution. This result further reveals the mechanism of the constitution type in Mongolian medicine and provides a reference for the treatment of related diseases.","PeriodicalId":23692,"journal":{"name":"World Journal of Traditional Chinese Medicine","volume":"8 1","pages":"539 - 547"},"PeriodicalIF":4.4,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43980622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Isolation and identification of two flavonoid compounds from acclimatized Angelica acutiloba kitagawa growing in Vietnam 越南水培尖叶当归中两种黄酮类化合物的分离鉴定

IF 4.4 3区医学

World Journal of Traditional Chinese Medicine Pub Date : 2022-07-01 DOI: 10.4103/2311-8571.352471

Thi Tam Pham, Thi Cuc Le, V. Tran, Van Thanh Nguyen

{"title":"Isolation and identification of two flavonoid compounds from acclimatized Angelica acutiloba kitagawa growing in Vietnam","authors":"Thi Tam Pham, Thi Cuc Le, V. Tran, Van Thanh Nguyen","doi":"10.4103/2311-8571.352471","DOIUrl":"https://doi.org/10.4103/2311-8571.352471","url":null,"abstract":"Traditional Vietnamese Medicine has its own development based on the local endemic herbs, but it also inherits from Traditional Chinese Medicine using Chinese herbal medicines. Throughout the history of cultural exchange between two countries, the adoption of Chinese Danggui, Angelica sinensis (Oliv.) Diels., has been made by Vietnamese traditional medicine practitioners for a long time. However, the acclimatization has never been successful. Japanese Danggui, or Angelica acutiloba Kitagawa, is recently being acclimatized and cultivated in several Vietnamese regions. Despite the huge climate change between the two countries, the herb adapted exquisitely well to the humid tropical climate. However, so far, there are no studies that have evaluated the effect of acclimatization on the overall quality of this medicinal herb. The aim of our study is screening secondary metabolites of this acclimatized herb for new natural compound(s), if any. The analysis of flavonoid fraction from this herb led to the identification of two known compounds which previously have not been isolated from this species elsewhere. This detection showed that the herb has reacted to the new environment.","PeriodicalId":23692,"journal":{"name":"World Journal of Traditional Chinese Medicine","volume":"8 1","pages":"413 - 416"},"PeriodicalIF":4.4,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44408577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuroprotective effect of electroacupuncture against acute ischemic stroke via PI3K-Akt-mTOR pathway-mediated autophagy 电针通过PI3K-Akt-mTOR途径介导的自噬对急性缺血性脑卒中的神经保护作用

IF 4.4 3区医学

World Journal of Traditional Chinese Medicine Pub Date : 2022-07-01 DOI: 10.4103/2311-8571.333712

Velika Yovitania, Qin-hui Fu, J. Pei, Hua Zhou

引用次数: 9

L-tyrosine metabolic pathway in microorganisms and its application in the biosynthesis of plant-derived natural products 微生物中的L-酪氨酸代谢途径及其在植物天然产物生物合成中的应用

IF 4.4 3区医学

World Journal of Traditional Chinese Medicine Pub Date : 2022-07-01 DOI: 10.4103/wjtcm.wjtcm_16_22

Yi-wen Zhang, Feng Nie, Xiao-yu Zheng, Shu-juan Zhao

引用次数: 1

International clinical practice guideline of Chinese medicine retinal vein occlusion 中医药视网膜静脉阻塞国际临床实践指南

IF 4.4 3区医学

World Journal of Traditional Chinese Medicine Pub Date : 2022-07-01 DOI: 10.4103/2311-8571.350881

Li-Ke Xie, X. Hao

引用次数: 0

High-performance liquid chromatography fingerprint of marine traditional Chinese medicine haliotidis 海洋中药海胆的高效液相色谱指纹图谱

IF 4.4 3区医学

World Journal of Traditional Chinese Medicine Pub Date : 2022-07-01 DOI: 10.4103/wjtcm.wjtcm_71_21

Qing Zhao, Shuyi Song, Meng-Qi Zhang, Xin Li, Yang Liu, Chang-Yun Wang

{"title":"High-performance liquid chromatography fingerprint of marine traditional Chinese medicine haliotidis","authors":"Qing Zhao, Shuyi Song, Meng-Qi Zhang, Xin Li, Yang Liu, Chang-Yun Wang","doi":"10.4103/wjtcm.wjtcm_71_21","DOIUrl":"https://doi.org/10.4103/wjtcm.wjtcm_71_21","url":null,"abstract":"Objective: Haliotidis, the dried muscle of abalone, has long been used as a marine traditional Chinese medicine (TCM) due to its high medicinal and nutritive values, whereas few reports contributed to its quality control. This study aimed to establish the high-performance liquid chromatography (HPLC) fingerprints of Haliotidis. Materials and Methods: The HPLC fingerprints of Haliotidis, the manufacturing products of dried muscle of abalone, were analyzed by reverse-phase HPLC, using a YMC HPLC C18 column (250 mm × 4.6 mm, 5 μm). The gradient elution mode was applied with mobile phase starting from 5% acetonitrile and 0.1% phosphoric acid aqueous solution to 100% acetonitrile in 70 min at a flow rate of 1.0 mL/min. The detection wavelength was set at 190 nm. Results: Through compared the HPLC fingerprint chromatograms of 14 batches of Haliotidis, 25 peaks were assigned as the characteristic common peaks, of which one index component L-phenylalanine was identified by comparison with its standard substance. The established HPLC fingerprint analysis method of Haliotidis was validated with good precision, repeatability, and stability. Based on the above study, a reference HPLC fingerprint chromatogram of Haliotidis was proposed. Conclusions: It is the first time to establish the HPLC fingerprint chromatogram of TCM Haliotidis, which could contribute to the establishment of its quality control system.","PeriodicalId":23692,"journal":{"name":"World Journal of Traditional Chinese Medicine","volume":"8 1","pages":"446 - 452"},"PeriodicalIF":4.4,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44403099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the mechanism of Tripterygium wilfordii against cancer using network pharmacology and molecular docking 应用网络药理学和分子对接技术探讨雷公藤抗癌症作用机制

IF 4.4 3区医学

World Journal of Traditional Chinese Medicine Pub Date : 2022-07-01 DOI: 10.4103/2311-8571.344544

Shuixiu Xiao, Shao Li, Wan-Xian Fang, Jv Chen, Hai-jian Li, Yongli Situ

{"title":"Exploring the mechanism of Tripterygium wilfordii against cancer using network pharmacology and molecular docking","authors":"Shuixiu Xiao, Shao Li, Wan-Xian Fang, Jv Chen, Hai-jian Li, Yongli Situ","doi":"10.4103/2311-8571.344544","DOIUrl":"https://doi.org/10.4103/2311-8571.344544","url":null,"abstract":"Background: The root of Tripterygium wilfordii (Tripterygii radix), a natural powerful traditional Chinese medicine (TCM) for various diseases treatment, has been used for centuries in the Asian countries as anti-rheumatoid arthritis (RA) agent, antioxidant agent, and anti-inflammatory agent. Its combination with other herbs in treating RA has been explored. The anti-RA effect of T. wilfordii for cancer treatment has been supported by some evidence. Aims and Objectives: To investigate the anticancer mechanism of T. wilfordii, bioinformatics databases were used to identify its active ingredients. Materials and Methods: Target proteins associated with cancer were determined using a network pharmacology analysis platform, and 25 key active compounds and 55 key targets of T. wilfordii were identified in our study. A common potential mechanism of T. wilfordii involvement in cancer was disclosed by in-depth network analysis of diseases, functions, and pathways. Finally, the analysis results of the TCM-disease target protein interaction network revealed 5 potential targets; subsequently, a total of 30 targets (these 5 targets, as well as 25 previously identified compounds) were subjected to molecular docking. Results: Our results showed that the therapeutic effect of T. wilfordii in cancer is characterized by multiple components, targets, and pathways. The regulation of signaling pathways such as Kaposi sarcoma-associated herpes virus infection, colorectal cancer, small-cell lung cancer, and prostate cancer may be the important pharmacodynamic basis of anticancer therapy. Conclusion: Triptonoditerpenic acid inhibited proliferation and induced apoptosis in SW480 cells. The mechanism may be related to the downregulation of Bcl-2 expression, upregulation of Bax mRNA expression, and expression inhibition of PTGS2.","PeriodicalId":23692,"journal":{"name":"World Journal of Traditional Chinese Medicine","volume":"8 1","pages":"417 - 425"},"PeriodicalIF":4.4,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47919297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Systematic review and meta-analysis of acupuncture for pain caused by liver cancer 针灸治疗肝癌所致疼痛的系统评价与meta分析

IF 4.4 3区医学

World Journal of Traditional Chinese Medicine Pub Date : 2022-07-01 DOI: 10.4103/2311-8571.351510

Xiao-wen Zhang, Yunpeng Gu, Huan-gan Wu, Kun Li, Rui Zhong, Qin Qi, Pin Wu, Jun-Hwan Ji, H. Liu, Yan Huang, Chang-Gue Son, Luyi Wu

{"title":"Systematic review and meta-analysis of acupuncture for pain caused by liver cancer","authors":"Xiao-wen Zhang, Yunpeng Gu, Huan-gan Wu, Kun Li, Rui Zhong, Qin Qi, Pin Wu, Jun-Hwan Ji, H. Liu, Yan Huang, Chang-Gue Son, Luyi Wu","doi":"10.4103/2311-8571.351510","DOIUrl":"https://doi.org/10.4103/2311-8571.351510","url":null,"abstract":"Objective: The objective of this study is to systematically review and analyze the efficacy of acupuncture for pain caused by primary liver cancer (PLC). Materials and Methods: We searched databases, including PubMed, Medline, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Chinese Science and Technology Periodicals Database (VIP), Wanfang, and SinoMed/Chinese Biomedical Database (CBM), and retrieved randomized controlled trials (RCTs) that used acupuncture as the primary intervention to treat pain caused by PLC. Two investigators then screened the articles, extracted and pooled data, and evaluated the risk of bias of the included articles according to the Cochrane Handbook. RevMan5.3 was used for the meta-analysis of eligible RCTs. Results: A total of 145 articles were retrieved; after screening, 8 RCTs involving 496 patients were eventually included in this meta-analysis. The results showed that acupuncture effectively improved cancer pain and was superior to Western medicine. Moreover, acupuncture was fast-acting for pain relief, prolonged the relief, and prevented relapse. Its adverse reaction rate was also significantly lower than that of Western medicine. No significant difference was observed in Visual Analog Scale score between acupuncture and Western medicine. Conclusion: Acupuncture relieves pain caused by liver cancer and can be used as an adjunct and alternative therapy for drug treatment. The existing research evidence is not yet objective or comprehensive, and more rigorous clinical trials are needed to validate the results.","PeriodicalId":23692,"journal":{"name":"World Journal of Traditional Chinese Medicine","volume":"8 1","pages":"402 - 412"},"PeriodicalIF":4.4,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43117914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7