Urologiia最新文献

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[Chronical fermentative inflammation and recurrent neck bladder stricture due to complications of pancreas transplan- tation]. 胰腺移植并发症引起的慢性发酵性炎症和复发性颈膀胱狭窄。
Urologiia Pub Date : 2026-09-01
V Bazaev V, A Vinogradov A, V Dutov V, A Podoynitsyn A
{"title":"[Chronical fermentative inflammation and recurrent neck bladder stricture due to complications of pancreas transplan- tation].","authors":"V Bazaev V, A Vinogradov A, V Dutov V, A Podoynitsyn A","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A clinical observation of the development of complications in the form of recurrent sclerosis (stricture) of the bladder neck in a patient following pancreas transplantation for type 1 diabetes mellitus with the imposition of duodenocystoanastomosis is presented.Severe enzymuria led to the development of bladder neck sclerosis with clinical symptoms of bladder outlet obstruction, accompanied by chronic urinary tract infection and inflammatory changes in the lower urinary tract. Previous transurethral resection of the stenotic bladder neck did not provide a lasting positive effect and resulted in recurrent bladder outlet obstruction 5 years later. The authors believe the recurrence of bladder neck stricture is due to impaired tissue regeneration in the resection area, coupled with recurrent infection and ongoing enzymuria. A relevant solution to this problem is a modified pancreas transplantation technique with enzyme diversion to the small intestine.</p>","PeriodicalId":23546,"journal":{"name":"Urologiia","volume":" 4","pages":"126-130"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Comparative analysis of comprehensive treatment outcomes in patients with chronic bacterial prostatitis with the addition of the multicomponent complex AndrOPREN]. 【添加多组分复合物AndrOPREN对慢性细菌性前列腺炎患者综合治疗效果的比较分析】。
Urologiia Pub Date : 2026-09-01
D Chelidze I, P Bryanskikh E, Z Kindarov I, A Dukuzov D, M Arsanukaev I, R Gvasalia B
{"title":"[Comparative analysis of comprehensive treatment outcomes in patients with chronic bacterial prostatitis with the addition of the multicomponent complex AndrOPREN].","authors":"D Chelidze I, P Bryanskikh E, Z Kindarov I, A Dukuzov D, M Arsanukaev I, R Gvasalia B","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Type II chronic bacterial prostatitis is characterized by persistent infection, insufficient efficacy of standard therapy, and a high recurrence rate, which necessitates the search for additional treatment options.</p><p><strong>Aim: </strong>To evaluate the efficacy and safety of adding the multicomponent complex AndrOPREN to comprehensive therapy for type II chronic bacterial prostatitis.</p><p><strong>Materials and methods: </strong>This prospective, comparative, randomized study included 233 patients allocated to the main group (n=126) and the control group (n=107). In both groups, patients received standard therapy; men in the main group additionally received the multi-ingredient complex AndrOPREN at a dose of two capsules of No. 1 and two capsules of No. 2 daily for 1-2 months. The follow-up period was 60 days. Changes in symptoms according to the IPSS and QoL scores, urinalysis parameters, microscopy findings of expressed prostatic secretions, pathogen eradication, and biochemical safety parameters were assessed.</p><p><strong>Results: </strong>Improvement was observed in both groups and was more pronounced in the main group. By day 14, the median IPSS score was 14.0 [12.0; 16.0] vs. 18.0 [15.0; 20.0] in the control group (p<0.001); by day 60, the corresponding values were 7.0 [5.0; 9.0] and 11.0 [9.0; 13.0] (p<0.001). At the end of follow-up, the QoL score was 2.0 [1.0; 2.0] and 3.0 [2.0; 3.0], respectively. No microbial growth was detected in 91.2% and 80.4% of patients, respectively (p=0.026); Escherichia coli eradication was achieved in 91.7% and 76.9%, respectively. No biochemical changes indicative of nephrotoxicity or hepatotoxicity were detected.</p><p><strong>Discussion: </strong>The addition of the multicomponent complex AndrOPREN was associated with more rapid symptom resolution, a reduction in inflammatory changes, restoration of the secretory function of the prostate, and greater microbiological efficacy.</p><p><strong>Conclusion: </strong>The addition of the multicomponent complex AndrOPREN to comprehensive therapy for type II chronic bacterial prostatitis improves treatment efficacy while maintaining a favorable safety profile.</p>","PeriodicalId":23546,"journal":{"name":"Urologiia","volume":" 4","pages":"38-47"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Risk factors of postoperative urinary retention in patients with intradural extramedullary spinal cord tumors]. [硬膜内髓外脊髓肿瘤患者术后尿潴留的危险因素]。
Urologiia Pub Date : 2026-09-01
A Lysachev D, V Danilov G, A Chitadze A, V Zaitsev A, A Onoprienko R, A Zakirov B, S Brinyuk E, V Kaprovoy S, M Poluektov Yu, A Dzyubanova N, A Konovalov N, Yu Pushkar D
{"title":"[Risk factors of postoperative urinary retention in patients with intradural extramedullary spinal cord tumors].","authors":"A Lysachev D, V Danilov G, A Chitadze A, V Zaitsev A, A Onoprienko R, A Zakirov B, S Brinyuk E, V Kaprovoy S, M Poluektov Yu, A Dzyubanova N, A Konovalov N, Yu Pushkar D","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Postoperative urinary retention (POUR) is a well-known complication in patients with extramedullary spinal cord tumors and leads to additional complications which are associated with increase in treatment duration and costs. The goal of current study is to define statistically significant risk factors of POUR in patients with extramedullary spinal cord tumors.</p><p><strong>Materials and methods: </strong>The data of 221 patients (155 women and 66 men, aged 19 to 84 years) undergoing surgery for extramedullary spinal cord tumors at the N.N. Burdenko National Medical Research Center of Neurosurgery of the Ministry of Health of the Russian Federation from January 2019 to December 2022 were evaluated. Of these, 178 patients were included in the prospective analysis, and 43 patients - in the retrospective analysis (based on data obtained from electronic health records). Urological symptoms in patients in the prospective group were assessed by the Centers urologist before and after neurosurgical intervention. Neurological status and urinary function were assessed by neurologist and urologist using the modified JOA score.</p><p><strong>Results: </strong>A statistically significant association was established between multiple clinical and topographic-anatomical features of extramedullary tumors and postoperative urinary retention (POUR). Based on the results of multiparametric analysis, an algorithm for stratifying patients according to the risk of developing POUR was proposed.</p><p><strong>Conclusion: </strong>The conducted study demonstrates the association of POUR with a number of clinical and topographic-anatomical features of extramedullary tumors, which should be taken into account when planning surgical intervention and managing patients in the early postoperative period.</p>","PeriodicalId":23546,"journal":{"name":"Urologiia","volume":" 4","pages":"54-59"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The role of bladder ultrasound in the differential diagnosis of the acute phase of recurrent viral cystitis]. 【膀胱超声在复发性病毒性膀胱炎急性期鉴别诊断中的作用】。
Urologiia Pub Date : 2026-09-01
S M Alkhashash A, D Goncharov I, I Palenyi A, D Mezhidova A, S Ibishev Kh, I Kogan M
{"title":"[The role of bladder ultrasound in the differential diagnosis of the acute phase of recurrent viral cystitis].","authors":"S M Alkhashash A, D Goncharov I, I Palenyi A, D Mezhidova A, S Ibishev Kh, I Kogan M","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic recurrent cystitis (CRC) is one of the most common urinary tract diseases in women, characterized by a recurrent course. Diagnosis of CRC requires a comprehensive approach, including clinical assessment, laboratory, and instrumental methods. One of the key non-invasive methods used in the diagnosis and differential diagnosis of CRC of any origin is bladder ultrasound.</p><p><strong>Study objective: </strong>To study the ultrasound characteristics of the bladder in patients with CRC depending on the etiologic viral factor.</p><p><strong>Materials and methods: </strong>This prospective study included 162 sexually active women aged 20-45 years who had previously been diagnosed with CRC. Depending on the viral etiology identified by PCR diagnostics, patients with CRC were divided into three groups: Group 1 (n=121) - CRC of human papillomavirus etiology (CRC PVE), Group 2 (n=30) - CRC caused by the herpes virus (CRC GE), and Group 3 (n=11) - CRC caused by the Epstein-Barr virus (CRC EBE). Statistical data on bladder volume and wall thickness, as well as the presence of pathological formations, were compared.</p><p><strong>Results: </strong>In CRC PVE, bladder wall thickening (> 5 mm in 45.4% of patients), fibrous changes (51.3%), and polypoid formations (51.2%, primarily in the Lieto triangle) were noted. In cases of viral cystitis associated with hepatic encephalopathy, localized thickening of the trigone wall was observed (30%), while in cases of chronic cystitis associated with the Epstein-Barr virus, changes were minimal: volume loss in 20% and bladder sediment in 20%.</p><p><strong>Conclusions: </strong>Bladder ultrasound is an informative, noninvasive method that allows for the assessment of structural and functional changes in viral cystitis and the identification of an etiologic factor. However, definitive diagnosis requires a comprehensive examination, including clinical data, laboratory (including PCR), and endoscopic (cystoscopy) tests.</p>","PeriodicalId":23546,"journal":{"name":"Urologiia","volume":" 4","pages":"70-74"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Efficacy and safety of flexible ureteroscopy with a navigable suction ureteral access sheath versus mini-percutaneous nephrolithotomy for 23 cm renal stones: a retrospective study]. [柔性输尿管镜下可导航的输尿管吸入套与微型经皮肾镜取石术治疗23厘米肾结石的疗效和安全性:回顾性研究]。
Urologiia Pub Date : 2026-09-01
A Aloyan A, B Zulkarnaev A, M Iskanderov A, S Aloyan Zh, G Martov A, K Gadzhiev N
{"title":"[Efficacy and safety of flexible ureteroscopy with a navigable suction ureteral access sheath versus mini-percutaneous nephrolithotomy for 23 cm renal stones: a retrospective study].","authors":"A Aloyan A, B Zulkarnaev A, M Iskanderov A, S Aloyan Zh, G Martov A, K Gadzhiev N","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Flexible ureteroscopy using a flexible and navigable suction ureteral access sheath (FANS f-URS) has expanded the possibilities of endoscopic treatment of renal stones; however, its role in the management of renal stones more or equal 2 cm remains controversial.</p><p><strong>Aim: </strong>To compare the efficacy and safety of FANS f-URS and mini-percutaneous nephrolithotomy (mini-PCNL) for the treatment of 2-3cm renal stones.</p><p><strong>Materials and methods: </strong>This retrospective study included 39 patients who underwent endoscopic surgical treatment, including 19 patients who underwent FANS f-URS and 20 who underwent mini-PCNL. Baseline characteristics as well as intraoperative and postoperative outcomes were collected and compared between the two groups.</p><p><strong>Results: </strong>On the first postoperative day, the stone-free rate, defined as residual fragments less or equal 2 mm, was 78.9% in the FANS f-URS group and 50.0% in the mini-PCNL group (p=0.096). At 3 months, the stone-free rates were comparable (94.7% for FANS f-URS and 90.0% for mini-PCNL; p>0.999). FANS f-URS was associated with a smaller decrease in hemoglobin level (p<0.001), a lower postoperative leukocyte count (p=0.023), and a shorter hospital stay (p<0.001; the proportion of patients with a hospital stay of 1-2 days was 100.0% vs. 40.0%). The complication rate and incidence of infectious events did not differ between the groups. Both groups demonstrated a statistically significant improvement in quality of life, with no difference in the magnitude of change between the groups (p=0.081).</p><p><strong>Conclusion: </strong>FANS f-URS provides efficacy comparable to that of mini-PCNL for 2-3 cm renal stones, while offering a more favorable safety profile and postoperative recovery.</p>","PeriodicalId":23546,"journal":{"name":"Urologiia","volume":" 4","pages":"97-105"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The use of artificial intelligence, virtual, augmented, and mixed reality, and 3D technologies in the treatment of urolithiasis]. [人工智能、虚拟、增强和混合现实以及3D技术在尿石症治疗中的应用]。
Urologiia Pub Date : 2026-09-01
N Akopyan G, K Gasanova L, A Matkovskiy I, Z Dodov M, K Gadzhiev N, A Gorgotsky I, I Rudenko V, V Glybochko P
{"title":"[The use of artificial intelligence, virtual, augmented, and mixed reality, and 3D technologies in the treatment of urolithiasis].","authors":"N Akopyan G, K Gasanova L, A Matkovskiy I, Z Dodov M, K Gadzhiev N, A Gorgotsky I, I Rudenko V, V Glybochko P","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Urolithiasis is a common urological disease. Modern minimally invasive treatment methods require a high degree of precision. Artificial intelligence (AI), virtual reality (VR), augmented reality (AR), mixed reality (MR), and 3D modeling technologies are increasingly being introduced into clinical practice and medical education to improve the effectiveness of interventions.</p><p><strong>Aim: </strong>To systematically analyze current data on the use of AI, VR, AR, MR, and 3D technologies in the diagnosis and treatment of urolithiasis and in medical education.</p><p><strong>Materials and methods: </strong>An analytical review of the literature was performed. Relevant publications were searched primarily in PubMed and The Journal of Urology. Particular emphasis was placed on studies published within the past 5 years, although earlier publications were also included to address historical and fundamental aspects.</p><p><strong>Results: </strong>These technologies demonstrate considerable potential in several key areas. 1) AI: prediction of treatment outcomes, including sepsis, percutaneous nephrolithotomy (PCNL) success, and spontaneous stone passage, with AUC values of up to 0.95; automated detection and segmentation of stones on CT and endoscopic images, with Dice similarity coefficient (DSC) values of up to 0.97; and determination of stone composition. 2) 3D technologies: preoperative 3D modeling and printing improve PCNL planning, shorten operative time, and increase the accuracy of percutaneous access. Uro Dyna-CT enables accurate intraoperative assessment of residual stone fragments. 3) AR/MR/VR: navigation systems reduce puncture time and the number of puncture attempts during PCNL. VR simulators, such as Uro Mentor, significantly improve endourological skills in trainees, reducing procedure time and the number of errors.</p><p><strong>Conclusions: </strong>Integration of AI, VR, AR, MR, and 3D modeling into the management of urolithiasis facilitates treatment personalization, improves procedural accuracy, reduces the risk of complications, and enables the development of effective training systems. Further studies, particularly in complex clinical scenarios, and validation in real-world clinical practice are required before these technologies can be widely implemented.</p>","PeriodicalId":23546,"journal":{"name":"Urologiia","volume":" 4","pages":"155-167"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Confocal laser endomicroscopy as a tool for intraoperative risk stratification of upper tract urothelial carcinoma]. 【共聚焦激光内镜作为上尿路上皮癌术中危险分层的工具】。
Urologiia Pub Date : 2026-09-01
G Martov A, A Shoaydarov M, V Dutov S, S Andronov A, Yu Zavarzin D
{"title":"[Confocal laser endomicroscopy as a tool for intraoperative risk stratification of upper tract urothelial carcinoma].","authors":"G Martov A, A Shoaydarov M, V Dutov S, S Andronov A, Yu Zavarzin D","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the diagnostic value of probe-based confocal laser endomicroscopy (CLE) in upper tract urothelial carcinoma (UTUC) during ureteroscopy and to determine its potential role in intraoperative risk stratification and selection of patients for kidney-sparing treatment.</p><p><strong>Materials and methods: </strong>From December 2019 to February 2023, CLE was performed in 17 patients with suspected UTUC. A Cellvizio system with a 0.85-mm (2.7 Ch) probe was used after intravenous administration of 10% sodium fluorescein. The obtained images were compared with the results of standard histopathological examination.</p><p><strong>Results: </strong>CLE was technically feasible in all 17 patients. A total of 85 video sequences were obtained, with a mean of 5 per case. The mean examination time was 5 minutes, and the mean imaging time for a single area was 68 seconds. No complications were observed. UTUC was diagnosed in 15 patients, whereas inflammatory mucosal changes were found in 2. In all 15 patients with tumors, the CLE-based assessment was concordant with the final histopathological diagnosis: 7 tumors were high-grade and 8 were low-grade.</p><p><strong>Conclusions: </strong>CLE is a safe and technically feasible method that allows real-time differentiation between low-grade and high-grade UTUC and may facilitate intraoperative decision-making between radical treatment and kidney-sparing treatment strategies.</p>","PeriodicalId":23546,"journal":{"name":"Urologiia","volume":" 4","pages":"117-125"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Use of predictive models for assessing perioperative outcomes of surgical treatment of localized renal parenchymal tumors: a critical review]. [应用预测模型评估局部肾实质肿瘤手术治疗围手术期预后:一项重要综述]。
Urologiia Pub Date : 2026-09-01
G Magomedov Ts, S Sirota E
{"title":"[Use of predictive models for assessing perioperative outcomes of surgical treatment of localized renal parenchymal tumors: a critical review].","authors":"G Magomedov Ts, S Sirota E","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this review was to critically evaluate the applicability of predictive models for planning nephron-sparing surgery in patients with localized renal parenchymal tumors. A narrative review of publications from 2020-2025 indexed in PubMed/MEDLINE, as well as earlier key studies, was performed. Nephrometry scores, regression models, machine learning, radiomics, and deep learning based on computed tomography data were analyzed. Nephrometry scores remain valuable as standardized tools for describing anatomical complexity but have limited ability to predict individual complications and composite outcomes. Multimodal models combining clinical and imaging features appear promising. A limited set of preoperative variables is often sufficient to predict postoperative renal function. Surgeon experience and the learning curve remain important factors but are frequently not incorporated into predictive models. Clinical implementation requires external validation, assessment of model calibration and clinical utility, while maintaining the leading role of the physician in clinical decision-making.</p>","PeriodicalId":23546,"journal":{"name":"Urologiia","volume":" 4","pages":"168-174"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Comparison of Quality of Life After Tandem Ureteral Stenting and Implantation of Metallic Mesh Ureteral Stents (Endoprostheses)]. [串联输尿管支架置入术与金属网状输尿管支架植入术后生活质量的比较]。
Urologiia Pub Date : 2026-09-01
S Serikov S, G Martov A, M Pshikhachev A, V Dutov S, S Andronov A
{"title":"[Comparison of Quality of Life After Tandem Ureteral Stenting and Implantation of Metallic Mesh Ureteral Stents (Endoprostheses)].","authors":"S Serikov S, G Martov A, M Pshikhachev A, V Dutov S, S Andronov A","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the impact of tandem ureteral stenting and implantation of metallic mesh ureteral stents (endoprostheses) on patients quality of life, and to determine the frequency and causes of repeat procedures during the first 3 months of follow-up.</p><p><strong>Materials and methods: </strong>The study included 45 patients who underwent either tandem ureteral stenting (n=28) or implantation of metallic mesh ureteral stents (n=17) between 2021 and 2025. Quality of life was assessed using the validated Russian version of the Ureteral Stent Symptom Questionnaire (USSQ). The questionnaire was filled by all patients on postoperative day 2 and again at 3 months after the procedure.</p><p><strong>Results: </strong>No statistically significant differences between the groups across any of the USSQ domains were detected on the 2nd day after the surgery (p>0.05). At 3 months, patients with metallic mesh stents demonstrated significantly better quality of life scores compared with the tandem stenting group, particularly in the domains of urinary symptoms (p<0.001), pain (p=0.041) and general health (p=0.022). The rate of repeat procedures within 3 months was 21.4% in the tandem stenting group and 23.5% in the metallic stent group (p=1.000). In the tandem group, repeat hospital stay was demanded primarily due to drainage dysfunction, while in the metallic stent group it was mainly attributed to stent migration or mucosal hyperplasia at the uncovered ends of the device.</p><p><strong>Conclusion: </strong>Metallic mesh ureteral stents provide superior quality of life compared with tandem ureteral stenting while keeping comparable repeat procedure rates. Owing to their durable design and favorable patient-reported outcomes, these stents may represent a viable and potentially preferred option for long-term urinary drainage in patients with recurrent ureteral strictures or contraindications to reconstructive surgery.</p>","PeriodicalId":23546,"journal":{"name":"Urologiia","volume":" 4","pages":"81-87"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Microbial contamination of urinary calculi depending on their chemical composition]. [微生物污染尿路结石取决于其化学成分]。
Urologiia Pub Date : 2026-09-01
N Khotko D, I Khotko A, B Bucharskaya A, V Polukonova N, I Tarasenko A, R Altynbaev R, M Popkov V
{"title":"[Microbial contamination of urinary calculi depending on their chemical composition].","authors":"N Khotko D, I Khotko A, B Bucharskaya A, V Polukonova N, I Tarasenko A, R Altynbaev R, M Popkov V","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Microbial contamination of urinary calculi and its relationship with stone composition remain insufficiently studied despite the high incidence of infectious complications of urolithiasis.</p><p><strong>Objective: </strong>To evaluate microbial contamination of urinary calculi depending on their chemical composition and to compare the results of culture-based and molecular genetic analyses.</p><p><strong>Materials and methods: </strong>The study included 96 patients who underwent mini-percutaneous nephrolithotripsy. A total of 108 calculi samples were analyzed. The chemical composition was determined by polarization microscopy. Microbiological assessment included culture-based methods and 16S rRNA gene sequencing using nanopore sequencing technology.</p><p><strong>Results: </strong>Positive culture results were obtained in 43 (39.8%) cases. In the group of infection-related stones (carbonate apatite), microorganisms were detected in 100% of cases, whereas in metabolic stones the detection rate ranged from 26.7% to 31.7%. The most frequently identified microorganisms were Enterococcus faecalis, Streptococcus spp., Pseudomonas aeruginosa, and Klebsiella pneumoniae. Using 16S rRNA sequencing, polymicrobial communities, including anaerobic microorganisms, were identified in 18.5% of culture-negative samples.</p><p><strong>Conclusion: </strong>Microbial contamination is detected in both infection-related and metabolic urinary calculi, suggesting that urinary stones may serve as a potential reservoir of microbial infection.</p>","PeriodicalId":23546,"journal":{"name":"Urologiia","volume":" 4","pages":"16-21"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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