Van Medical Journal最新文献_第8页

Nursing Care of a Patient with Arteriovenouz Malformation According to Orem’s Self-Care Deficit Nursinde Theory: Case Report 根据Orem自我护理缺陷护理理论对动静脉畸形患者的护理:1例报告

Van Medical Journal Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.01212

A. Özdemİr, Ş. İ. Güner, A. M. Geyik

引用次数: 0

The Surveyans of Colonisation of Vancomycin Resistant Enterococci and Investigation Antibiotic Susceptibility and Risk Factors 万古霉素耐药肠球菌定植调查及药敏和危险因素调查

Van Medical Journal Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.26428

Irfan Binici, M. Karahocagil, M. Sünnetçioğlu, M. Parlak

引用次数: 1

Evaluation of the Relationship Between Eosinophil to Monocyte Ratio and Ieft Ventricle Ejection Fraction in Patients With Acute Coronary Syndrome 急性冠脉综合征患者嗜酸性粒细胞与单核细胞比值与左心室射血分数关系的评价

Van Medical Journal Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.18199

Ş. Külahçıoğlu, Kadir Bıyıklı, D. Çeneli, S. Tanyeri, B. Kültürsay, B. Keskin, Okan Korun, E. Cakmak, Enver Yücel, A. Karagoz, I. Tanboğa, C. Kaymaz

引用次数: 0

A Comparison of the Quality of life and Personal Traits in Menopausal Women 绝经期妇女生活质量与个人特征的比较

Van Medical Journal Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.65148

Aliye Bulut, Handan Özcan, E. Arbağ

{"title":"A Comparison of the Quality of life and Personal Traits in Menopausal Women","authors":"Aliye Bulut, Handan Özcan, E. Arbağ","doi":"10.5505/vtd.2022.65148","DOIUrl":"https://doi.org/10.5505/vtd.2022.65148","url":null,"abstract":"Introduction: This study was planned to compare the quality of life and personal traits in menopausal women. Methods: The population of the study comprised women who applied to Family Health Centers (FHC) in the city center of Bingol (n=157). A survey form, which was prepared by the researcher as a result of evaluating the relevant literature and comprised three sections, was applied to the women who met the inclusion criteria. The first section of the survey consisted of a questionnaire questionin g the participants’ s ocio-demographic characteristics, obstetrical, gynecological, chronic disease history, information about the menopausal period and general health behaviors. The second section consisted of the “Menopause -Specific Quality of Life Questi onnaire (MSQLQ)” and the third section consisted of the Cervantes Personality Scale (CPS). Results: There was a positive significant correlation between the scores, obtained by the women who participated in the study, from the CPS emotional stability/neuroticism subscale and the MSQLQ scores, whereas there was a negative significant correlation between their sincerity/insincerity scores and MSQLQ scores. There was no statistically significant correlation between the extroversion/introversion subscale and MSQLQ symptoms. Conclusions: It was determined that the women had no adequate knowledge of this period which comprises nearly one third of their life, there were deficiencies in coping with menopausal symptoms and the quality of life of the women in the menopausal period was not at the required level. In the personality development phases, women should be encouraged for positive, emotionally stable and extrovert personality development and to use of healthy defense mechanisms.","PeriodicalId":23509,"journal":{"name":"Van Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89758557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic Significance of Ratio of Metastatic Lymph Nodes in Colorectal Cancer Patients Treated with Curative Resection 结直肠癌根治性切除患者淋巴结转移率的预后意义

Van Medical Journal Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.24855

K. Gülben, O. Uyar, B. Öndeş

引用次数: 0

Relationship of Lysosomal Storage Diseases (LSD) with Autophagy 溶酶体贮积病(LSD)与自噬的关系

Van Medical Journal Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.95776

S. Keskin, I. Alkac, B. Çerçi

{"title":"Relationship of Lysosomal Storage Diseases (LSD) with Autophagy","authors":"S. Keskin, I. Alkac, B. Çerçi","doi":"10.5505/vtd.2022.95776","DOIUrl":"https://doi.org/10.5505/vtd.2022.95776","url":null,"abstract":"Lysosomes are organelles that break down damaged components or structures that have completed their task in the cell by the hydrolytic enzymes they contain and take part in the last step of the autophagic pathway. Autophagy, an evolutionarily conserved lysosomal pathway, is activated under stress conditions such as amino acid starvation, accumulation of unfolded proteins, or viral infection. The main task of autophagy is to remove damaged proteins, organelles and microorganisms that constitute the source of infection. During this degradation mechanism, autophagosomes are formed as a result of the interaction of lysosomes and autophagic vesicles carrying damaged proteins, and this formation is tightly controlled by cellular mechanisms. Damage during this interaction can disrupt cellular homeostasis and interfere with the survival of the organism. Lysosomal Storage Diseases (LDH) is one of the most common human genetic diseases that develop because of mutations on genes encoding lysosomal enzymes. To date, more than 70 LDHs have been identified. LDH is mainly caused by functional disorders of enzymes or lysosome-associated proteins in lysosomes. These disorders may cause undigested macromolecules to accumulate in the cells, compromising the proper functioning of the organs in which they are located. LDH can cause many systemic damages, especially in the nervous system, skeletal system, and reticuloendothelial system, especially in the early stages of the disease. Modulation and reactivation of autophagy is considered a new therapeutic approach for LDH. In this review, the general mechanisms of the relationship between lysosomal storage diseases and autophagy were evaluated together with treatment approaches.","PeriodicalId":23509,"journal":{"name":"Van Medical Journal","volume":"117 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79467044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can Titanium Elastic Nails be the First Treatment Choice in Pediatric Femoral Shaft Fractures? 钛弹性钉可以作为儿童股骨干骨折的首选治疗方法吗?

Van Medical Journal Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.34538

Duran Topak, Mustafa Özdemir, F. Doğar, Kadir İsmail Dere, Halil Mutlu, Ökkeş Bilal

引用次数: 1

Fahr Syndrome Diagnosed by the First Attack Psychosis: A Case Report 首次发作精神病诊断Fahr综合征1例

Van Medical Journal Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.35682

Yavuz Selim Atan, U. Kırlı

引用次数: 0

Apoptotic Effect Of Neferine On Cervical Cancer Cells (HeLa) 莲子碱对宫颈癌细胞凋亡的影响

Van Medical Journal Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.87094

Gozde Sahin, T. Duran, Serkan Küççüktürk, N. Koçak, Denizhan Bayramoğlu, A. Kebapçılar, Ç. Çelik