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Penile and Testicular Incarceration with a Metal Foreign Body: Full Recovery of Erectile Function after 4 Days of Entrapment. 金属异物嵌顿阴茎和睾丸--嵌顿 4 天后勃起功能完全恢复。
IF 0.9 4区 医学
Urology Journal Pub Date : 2025-10-08 DOI: 10.22037/uj.v21i.8139
Dimitrije Jeremić, Žarko Dimitrić, Miroslav Tomić, Ines Kalači, Srđan Govedarica, Đorđe Filipović
{"title":"Penile and Testicular Incarceration with a Metal Foreign Body: Full Recovery of Erectile Function after 4 Days of Entrapment.","authors":"Dimitrije Jeremić, Žarko Dimitrić, Miroslav Tomić, Ines Kalači, Srđan Govedarica, Đorđe Filipović","doi":"10.22037/uj.v21i.8139","DOIUrl":"10.22037/uj.v21i.8139","url":null,"abstract":"<p><p>Penile incarceration with a foreign body is a rare urological emergency necessitating prompt intervention. We present a 59-year-old patient who entrapped his penis and right testicle with a metal thread reducer for sexual arousal four days prior to admission to the Emergency Room. Ultrasound revealed a significantly reduced Color Doppler signal in the right testicle and a completely absent signal in the penile artery. After admission, the metal reducer was removed using a hacksaw under analgosedation. Magnetic resonance imaging showed penile ischemic changes. The patient experienced a reduction in penile swelling, and parts of the skin highly suspected of necrosis recovered fully with preserved sensation. Despite penile ischemia on magnetic resonance imaging, the patient had a full recovery, obtaining normal erections. He was discharged six days after admission, presenting with a normal International Index of Erectile Function score on the follow-up exam.</p>","PeriodicalId":23416,"journal":{"name":"Urology Journal","volume":" ","pages":"215-216"},"PeriodicalIF":0.9,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142576680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Low-Frequency Acupuncture Therapy Based on the Midnight-Noon Ebb-Flow Concept for Central Neurogenic Bladder: A Randomized Controlled Trial. 基于午夜-中午针刺的低频针刺治疗中枢神经性膀胱的疗效:一项随机对照试验。
IF 0.9 4区 医学
Urology Journal Pub Date : 2025-10-08 DOI: 10.22037/uj.v22i.8280
Zhenjun Wang, Xuyan Zhou, Xinxing Liu, Yuan Xia, Yan Zhou, Lingyun Luo
{"title":"Efficacy of Low-Frequency Acupuncture Therapy Based on the Midnight-Noon Ebb-Flow Concept for Central Neurogenic Bladder: A Randomized Controlled Trial.","authors":"Zhenjun Wang, Xuyan Zhou, Xinxing Liu, Yuan Xia, Yan Zhou, Lingyun Luo","doi":"10.22037/uj.v22i.8280","DOIUrl":"10.22037/uj.v22i.8280","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to investigate the therapeutic efficacy and complications of low-frequency acupuncture therapy based on the Midnight-Noon Ebb-Flow concept in central neurogenic bladder (CNB).</p><p><strong>Materials and methods: </strong>This study was a prospective, randomized controlled trial. Sixty patients diagnosed with CNB without prior treatment were randomly divided into two groups: the control group (n = 30) was treated with basic rehabilitation training, and the treatment group (n = 30) was treated with basic rehabilitation training plus low-frequency acupuncture therapy based on the Midnight-Noon Ebb-Flow concept for 4 weeks. The fixed acupuncture points selected were: Sanyinjiao (bilateral), Zhongji (unilateral), and Diji (unilateral). The study compared pre- and post-treatment clinical curative effects, urodynamic indicators, urination status, the Neurogenic Bladder Symptom Score (NBSS), the Urinary Symptom Distress Scale (USDS), the World Health Organization Quality of Life Brief Inventory (WHOQOL-BREF), and the occurrence of adverse reactions and complications between the two groups.</p><p><strong>Results: </strong>The overall efficacy rate of 96.67% in the treatment group was significantly higher than that in the control group (86.67%) (P < 0.05). After treatment, the MBC, MFR, Pdet, DASUV, and WHOQOL-BREF scores significantly increased, while the RUV, DUF, DAUL, NBSS and USDS scores all decreased in both groups, with the treatment group showing significantly better results than the control group (P < 0.05). There was no statistically significant difference in adverse reactions and complication rates between the two groups (P > 0.05).</p><p><strong>Conclusion: </strong>Low-frequency acupuncture therapy based on the Midnight-Noon Ebb-Flow concept significantly improves bladder function and alleviates urinary difficulties in CNB, demonstrating good safety and considerable clinical applicability.</p>","PeriodicalId":23416,"journal":{"name":"Urology Journal","volume":" ","pages":"179-186"},"PeriodicalIF":0.9,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive Value of Systemic Inflammatory Markers in the Prognosis of Prostate Cancer with Variant Histology. 系统性炎症标志物对组织学变异前列腺癌预后的预测价值。
IF 0.9 4区 医学
Urology Journal Pub Date : 2025-10-08 DOI: 10.22037/uj.v22i.8378
Huseyin Aytac Ates, Semih Aktas, Muhammet Hilmi Enes Araci, Emrah Okucu, Berrin Yalcin, Hikmet Koseoglu
{"title":"Predictive Value of Systemic Inflammatory Markers in the Prognosis of Prostate Cancer with Variant Histology.","authors":"Huseyin Aytac Ates, Semih Aktas, Muhammet Hilmi Enes Araci, Emrah Okucu, Berrin Yalcin, Hikmet Koseoglu","doi":"10.22037/uj.v22i.8378","DOIUrl":"10.22037/uj.v22i.8378","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the potential role of systemic inflammatory markers in the management of Prostate Cancer (PCA) with variant pathology.</p><p><strong>Materials and methods: </strong>A retrospective analysis was conducted on 302 patients who underwent radical prostatectomy between 2014 and 2023. After applying exclusion criteria, 279 patients were included: 207 with adenocarcinoma and 72 with variant pathologies. Systemic inflammatory markers such as Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), Systemic Immune-Inflammation Index (SII), and Systemic Inflammation Response Index (SIRI) were compared between the groups.</p><p><strong>Results: </strong>Patients in the variant group were significantly older (p = 0.005). The frequencies of lymphovascular invasion (LVI), perineural invasion (PNI), and positive surgical margins (SM) were significantly higher in the variant histology group (p < 0.001, p = 0.014, and p < 0.001, respectively), as were ISUP grades (p < 0.001). Pretreatment PSA values were also significantly higher in the variant group (p < 0.001), as was the rate of subsequent radiotherapy (p < 0.001). However, no significant differences were found in NLR, PLR, SIRI, or SII values between the groups. Recurrence rates were significantly higher in the variant group (p < 0.05), but overall mortality did not differ.</p><p><strong>Conclusion: </strong>Systemic inflammation markers have limited value in predicting prognosis among patients with variant PCA. This highlights the complex role of inflammation in cancer progression and underscores the need for further research to identify more specific biomarkers for different PCA variants.</p>","PeriodicalId":23416,"journal":{"name":"Urology Journal","volume":" ","pages":"187-192"},"PeriodicalIF":0.9,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bladder Health in U.S. Shift Workers: A Cross-Sectional Study (NHANES). 美国轮班工人膀胱健康:一项横断面研究(NHANES)。
IF 0.9 4区 医学
Urology Journal Pub Date : 2025-10-08 DOI: 10.22037/uj.v21i.8265
Jianjun Diao, Li Xie, Bo Wu, Lin Chen, Hao Jing
{"title":"Bladder Health in U.S. Shift Workers: A Cross-Sectional Study (NHANES).","authors":"Jianjun Diao, Li Xie, Bo Wu, Lin Chen, Hao Jing","doi":"10.22037/uj.v21i.8265","DOIUrl":"10.22037/uj.v21i.8265","url":null,"abstract":"<p><strong>Purpose: </strong>Working during non-traditional hours is becoming more prevalent in modern societies and presents a significant hurdle to an individual's circadian rhythm. We examined the bladder health of shift workers in the United States by analyzing information obtained from the National Health and Nutrition Examination Survey.</p><p><strong>Materials and methods: </strong>National Health and Nutrition Examination Survey (NHANES) datasets from 2005 to 2010 were utilized. Regression analyses were used to assess the association between shift work and bladder health (stress incontinence, urge incontinence, and nocturia) by adjusting for age, race, education, smoking, and other factors.</p><p><strong>Results: </strong>The percentage of non-Hispanic Black individuals was notably higher among shift workers (25.8% vs. 17.8%). Among shift workers, there was a lower percentage of individuals with a college degree or higher compared to day workers. Shift work was found to be associated with nocturia in men in the unadjusted model (OR=1.2, 95%CI=1.0-1.5, p = 0.038). However, the adjusted results indicate that the connection is not statistically significant (Adjusted Model II: OR=1.2, 95%CI=1.0-1.5, p = 0.105). Similarly, no statistically significant association was observed between shift work and nocturia in women. There was also no significant relationship between shift work and Stress Urinary Incontinence (SUI) in men or women. The results from the fully adjusted model (Adjusted Model II) indicate a significant association between shift work and the prevalence of Urgency Urinary Incontinence (UUI) in women (OR=1.2, 95%CI=1.0-1.5, p = 0.041).</p><p><strong>Conclusion: </strong>Results of this cross-sectional study indicated that shift work was associated with a higher risk of UUI in women. Further research is needed to explore this relationship.</p>","PeriodicalId":23416,"journal":{"name":"Urology Journal","volume":" ","pages":"209-214"},"PeriodicalIF":0.9,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective Analysis of Surgical Outcomes Following Scarless Orchiopexy via Either Scrotal Incision or Single-Site Transumbilical Laparoscopy. 经阴囊切口或单部位经脐腹腔镜无瘢痕睾丸切除术的手术效果回顾性分析。
IF 0.9 4区 医学
Urology Journal Pub Date : 2025-10-08 DOI: 10.22037/uj.v22i.8343
Chu Zhang, Qingqing Tian, Xiang Zhao, Kechi Yu, Peng Cao, Yonghua Niu, Xuefeng Zhou, Ning Li
{"title":"Retrospective Analysis of Surgical Outcomes Following Scarless Orchiopexy via Either Scrotal Incision or Single-Site Transumbilical Laparoscopy.","authors":"Chu Zhang, Qingqing Tian, Xiang Zhao, Kechi Yu, Peng Cao, Yonghua Niu, Xuefeng Zhou, Ning Li","doi":"10.22037/uj.v22i.8343","DOIUrl":"10.22037/uj.v22i.8343","url":null,"abstract":"<p><strong>Purpose: </strong>The surgical approach to pediatric cryptorchidism has traditionally been the inguinal pathway. However, that has changed with the increased use of scrotal incision and single-site transumbilical laparoscopy, both of which result in a scarless surgical incision. We aimed to review our experience with the combined utilization of these two methods for the treatment of pediatric cryptorchidism and evaluate the surgical outcomes.</p><p><strong>Materials and methods: </strong>This retrospective case series included 267 children who underwent scarless orchiopexy between January 2019 and December 2022. Data were gathered from case and operative records. Testicular retraction, testicular atrophy, other complications, cosmetic outcomes, and parental satisfaction were evaluated.</p><p><strong>Results: </strong>A total of 267 children (aged 1-7.4 years, median 1.8 years) with palpable and nonpalpable undescended testes underwent scarless orchiopexy at our center. Among them, 58 (21.7%) were treated with a scrotal incision and 209 (78.3%) underwent single-site transumbilical laparoscopic surgery. The follow-up period ranged from 6 to 53 months, with an average of 26.2 months. During the follow-up period, testicular retraction (4 cases, 1.5%) and atrophy (5 cases, 1.9%) occurred in the laparoscopic group. One child in the laparoscopic group developed a hydrocele but recovered after 3 months. In most cases (98.9%), the scars were invisible, indicating an excellent cosmetic effect.</p><p><strong>Conclusion: </strong>The combination of scrotal incision and transumbilical laparoscopic orchiopexy can resolve cryptorchidism in children at different locations and achieve successful outcomes with a low rate of postoperative complications and good cosmetic results.</p>","PeriodicalId":23416,"journal":{"name":"Urology Journal","volume":" ","pages":"193-198"},"PeriodicalIF":0.9,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screening of Relevant Genes and Signalling Pathways Affecting Adult Urosepsis: A Bioinformatic Analysis. 筛选相关基因和信号通路影响成人尿脓毒症:生物信息学分析。
IF 0.9 4区 医学
Urology Journal Pub Date : 2025-10-08 DOI: 10.22037/uj.v22i.7933
Xu Xi Shi, Lu Rong Rong, Huang Zhong Wei
{"title":"Screening of Relevant Genes and Signalling Pathways Affecting Adult Urosepsis: A Bioinformatic Analysis.","authors":"Xu Xi Shi, Lu Rong Rong, Huang Zhong Wei","doi":"10.22037/uj.v22i.7933","DOIUrl":"10.22037/uj.v22i.7933","url":null,"abstract":"<p><strong>Purpose: </strong>The cellular and molecular pathophysiology of urosepsis, a condition caused by a urinary tract infection spreading to the bloodstream, involves complex epigenetic behavior. The objective of this study was to identify relevant genes and signaling pathways in adult urosepsis through a bioinformatic analysis of differentially expressed genes (DEGs).</p><p><strong>Materials and methods: </strong>In this in silico study, the GSE69528 dataset, containing 138 total RNA blood samples from patients with sepsis and uninfected controls, was obtained from the Gene Expression Omnibus (GEO) database. Microarray data were analyzed using GEO2R tools and R software. DEGs were identified using a fold change (FC) cutoff of > 1.5 or < 0.67 and a significance level of p < 0.05. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were used to determine the enriched pathways of DEGs before constructing protein-protein interaction (PPI) networks with STRING and Cytoscape.</p><p><strong>Results: </strong>A total of 108 DEGs were identified, comprising 67 upregulated and 41 downregulated genes. GO and KEGG analyses revealed that these DEGs were significantly enriched in pathways such as the complement and coagulation cascade, neutrophil degranulation, negative regulation of interferon-gamma response, T-cell activation, and granulocyte differentiation. The PPI network analysis identified 67 nodes with 110 interactions, from which CEACAM8, MPO, and RETN were identified as hub genes. Overexpression of CEACAM8 and MPO and suppression of RETN may be associated with a better disease prognosis.</p><p><strong>Conclusion: </strong>The identified hub genes-CEACAM8, MPO, and RETN-are predicted to be significant biomarkers in the prognosis and progression of sepsis. These genes could be targeted for the discovery of new therapeutic drugs for treating and managing urosepsis.</p>","PeriodicalId":23416,"journal":{"name":"Urology Journal","volume":" ","pages":"203-208"},"PeriodicalIF":0.9,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dorsal Penile Curvature in Children: A Review. 儿童阴茎背侧弯曲。
IF 0.9 4区 医学
Urology Journal Pub Date : 2025-10-08 DOI: 10.22037/uj.v22i.8579
Ramazan Karabulut, Zafer Turkyilmaz, Cem Kaya, Leyla Nur Türker, Ali Atan, Kaan Sonmez
{"title":"Dorsal Penile Curvature in Children: A Review.","authors":"Ramazan Karabulut, Zafer Turkyilmaz, Cem Kaya, Leyla Nur Türker, Ali Atan, Kaan Sonmez","doi":"10.22037/uj.v22i.8579","DOIUrl":"10.22037/uj.v22i.8579","url":null,"abstract":"<p><strong>Purpose: </strong>To review the current literature on dorsal penile curvature (DPC) in children, including its etiology, diagnosis, and principles of treatment.</p><p><strong>Materials and methods: </strong>A literature review was conducted on DPC in children, focusing on its etiology (e.g., skin tethering, corporal disproportion), association with other conditions such as hypospadias and epispadias, and surgical treatment methods.</p><p><strong>Results: </strong>DPC is a rare condition, often associated with neonatal circumcision, hypospadias, or epispadias. The etiology includes skin ties, fibrotic tissues, and asymmetric corporal development. Spontaneous resolution can occur, especially in cases following circumcision. Surgical correction is typically considered for curvatures of 30° or greater that are functionally concerning. Common surgical techniques include ventral plication, wedge resection (Nesbit procedure), and grafting.</p><p><strong>Conclusion: </strong>While mild DPC often requires no intervention, surgical correction should be considered for significant curvatures (≥ 30°) to prevent future functional issues. Cases that develop after neonatal circumcision may resolve spontaneously.</p>","PeriodicalId":23416,"journal":{"name":"Urology Journal","volume":" ","pages":"176-178"},"PeriodicalIF":0.9,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Regional Genetic Study of Primary Monosymptomatic Nocturnal Enuresis Using Chromosomal Microarray Analysis. 区域遗传研究:单症状夜间遗尿和阵列技术。
IF 0.9 4区 医学
Urology Journal Pub Date : 2025-10-08 DOI: 10.22037/uj.v22i.8501
Oğuzhan Yarali, Yüksel Sümeyra Naralan
{"title":"A Regional Genetic Study of Primary Monosymptomatic Nocturnal Enuresis Using Chromosomal Microarray Analysis.","authors":"Oğuzhan Yarali, Yüksel Sümeyra Naralan","doi":"10.22037/uj.v22i.8501","DOIUrl":"10.22037/uj.v22i.8501","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the genetic heterogeneity of primary monosymptomatic nocturnal enuresis (PMNE) and assess potential genetic variants contributing to its etiology.</p><p><strong>Materials and methods: </strong>A total of 92 children aged 5-15 years with a positive family history of PMNE were evaluated. All patients underwent detailed urological and nephrological assessments to exclude organic causes. Genetic testing was performed using high-resolution chromosomal microarray technology to identify potential pathogenic variants.</p><p><strong>Results: </strong>No pathogenic or likely pathogenic copy number variations were identified. A small number of patients exhibited variants of uncertain significance (VUS), none of which were conclusively linked to PMNE after parental segregation analysis. Our findings challenge previous studies that reported significant genetic markers and highlight the complex genetic architecture of PMNE.</p><p><strong>Conclusion: </strong>This study reinforces the genetic heterogeneity of PMNE and suggests it follows a polygenic and multifactorial inheritance pattern. Further research using whole-exome and whole-genome sequencing is needed to explore potential genetic contributors alongside environmental factors.</p>","PeriodicalId":23416,"journal":{"name":"Urology Journal","volume":" ","pages":"199-202"},"PeriodicalIF":0.9,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Polymorphisms in Estrogen Receptors with non-obstructive Azoospermia and Severe Secretory Oligozoospermia:a Meta-Analysis. 雌激素受体多态性与非梗阻性无精子症和严重分泌性少精子症的关系:一项 Meta 分析。
IF 0.9 4区 医学
Urology Journal Pub Date : 2025-09-09 DOI: 10.22037/uj.v21i.8118
Aiqiao Zhang, Shangren Wang, Li Liu, Zhexin Zhang, Yang Pan, Shuai Niu, Xiaoqiang Liu
{"title":"Association of Polymorphisms in Estrogen Receptors with non-obstructive Azoospermia and Severe Secretory Oligozoospermia:a Meta-Analysis.","authors":"Aiqiao Zhang, Shangren Wang, Li Liu, Zhexin Zhang, Yang Pan, Shuai Niu, Xiaoqiang Liu","doi":"10.22037/uj.v21i.8118","DOIUrl":"10.22037/uj.v21i.8118","url":null,"abstract":"<p><strong>Purpose: </strong>Estrogen receptor (ER) genes play key roles in male and female reproduction. Non-obstructive azoospermia (NOA) and severe secretory oligozoospermia (SOL) are the most severe and complex conditions impacting male fertility. This meta-analysis aimed to study the association between PvuII ( rs2234693, 397T>C ), XbaI ( rs9340799, 351G>A ), AluI (1730G>A, rs4986938), and RsaI (1082G>A, rs1256049) polymorphisms and spermatogenic failure.</p><p><strong>Materials and methods: </strong>The literature in PubMed, Medline, Embase, Web of Science, Cochrane Library, China Science and Technology Journal Database, WanFang data, and China National Knowledge Infrastructure databases were systematically searched, and a meta-analysis was conducted to investigate the association between polymorphism in estrogen receptors and spermatogenic failure. According to a set criterion, 10 studies were included for analyses.</p><p><strong>Results: </strong>ER α XbaI polymorphism was a decreased risk of NOA. The ER α PvuII polymorphisms does not associate with NOA and SOL. ER β AluI polymorphism increased the risk of NOA in Caucasian population. ER β RsaI polymorphism was a decreased risk of NOA and SOL in Caucasian males.</p><p><strong>Conclusion: </strong>The ER α XbaI and ER β RsaI polymorphisms are associated with the risk of NOA and SOL.</p>","PeriodicalId":23416,"journal":{"name":"Urology Journal","volume":" ","pages":"123-131"},"PeriodicalIF":0.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141306852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimalist Approach for HoLEP with A Low-Power Holmium Source: A Retrospective Study. 使用低功率钬源进行钬激光治疗的最小化方法:回顾性研究。
IF 0.9 4区 医学
Urology Journal Pub Date : 2025-09-09 DOI: 10.22037/uj.v21i.8071
Ramazan Inan, Ibrahim Buldu
{"title":"Minimalist Approach for HoLEP with A Low-Power Holmium Source: A Retrospective Study.","authors":"Ramazan Inan, Ibrahim Buldu","doi":"10.22037/uj.v21i.8071","DOIUrl":"10.22037/uj.v21i.8071","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the efficacy and safety of very low-power Holmium Laser Enucleation of the Prostate (HoLEP) on a 30-W holmium laser source.</p><p><strong>Materials and methods: </strong>  With the approval of the local ethics committee, we retrospectively analysed 60 patients treated with HoLEP. There were 30 patients in the low-power (LP) group and 30 patients in the very low-power (VLP) group. For the LP group, we used a 60-W holmium laser machine. Throughout the en bloc process, we used laser settings of 2 J and 20 Hz. We used a 30-W low-power holmium source in the VLP group. We used laser settings of 2 J and 10 Hz. All patients were operated on by an experienced surgeon. We evaluated the surgical parameters and practicality of the low-power laser vs. the very low-power laser.</p><p><strong>Results: </strong>All patients underwent successful HoLEP in the very low-power group; it was not necessary to increase the output of the laser in any case. Mean preoperatively estimated prostate volume was 88.1 mL (range, 30-300 mL). Mean enucleation time and enucleation efficiency were 67.9 min (range, 25-150 min) and 0.99 gm/min (range, 0.8-1.8 gm/min), respectively. No patient required blood transfusion postoperatively. No stress urinary incontinence (SUI) was observed in the 3rd month postoperative follow-up.</p><p><strong>Conclusion: </strong>The use of a low-power laser source is encouraging for the learning curve of new surgeons who will begin HoLEP surgery; it can facilitate the adoption of HoLEP in developing countries, where the initial capital investment may be a major obstacle.</p>","PeriodicalId":23416,"journal":{"name":"Urology Journal","volume":" ","pages":"164-168"},"PeriodicalIF":0.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142576670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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