Tropical Medicine and Health最新文献

{"title":"Health needs assessment tool for identifying the health issues among community residents with unmet needs.","authors":"Yurie Kobashi","doi":"10.1186/s41182-025-00713-9","DOIUrl":"10.1186/s41182-025-00713-9","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to discuss the method for designing a community project, especially in a resource-limited setting, using a health needs assessment tool, the Community Health Issues Interview Sheet, for the design of a project in the initial phase.</p><p><strong>Methods: </strong>The Community Health Issues Interview Sheet was developed; this tool applied more than four field and modified based on feedback from researchers and stakeholders.</p><p><strong>Results: </strong>When researchers from outside a target community design a community project, there are three factors to consider: resource size, target population, and focused health issues. The interview sheet was aimed at identifying priority health issues among the target population.</p><p><strong>Conclusions: </strong>All community projects should be well-designed, and priority health issues should be assessed using a health needs assessment tool, such as the interview sheet in the initial project stage. Further education for researchers about project design in communities with resource-limited settings should be provided, and research on the experience of using the health needs assessment tool should be accumulated.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"29"},"PeriodicalIF":3.6,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11853963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143493860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consumer behavior and its role in E. coli outbreaks: the impact of fast-food preparation practices and hygiene awareness.","authors":"Victor Oluwatomiwa Ajekiigbe, Ikponmwosa Jude Ogieuhi, Chidera Stanley Anthony, Ifeoluwa Sandra Bakare, Sopuruchukwu Anyacho, Praise Oluwatobi Ogunleke, Damilola Ifeoluwa Fatokun, Olufemi Akinmeji, Osineye Tolulope Ruth, Akintomiwa Kolawole Olaore, Oluwafemi Amusa, Chinonyelum Emmanuel Agbo","doi":"10.1186/s41182-025-00710-y","DOIUrl":"10.1186/s41182-025-00710-y","url":null,"abstract":"<p><strong>Background: </strong>The fast-food industry, a rapidly expanding business due to the influence of urbanization and busy lifestyles, has significantly shaped consumer food habits and quality food-seeking behavior. However, this fast-growing sector is frequently challenged by bacteria of clinical, microbiological, and economic importance, including Escherichia coli (E. coli). While many strains of E. coli are harmless and support digestion, pathogenic variants such as E. coli O157:H7 are responsible for severe foodborne illnesses, public health crises, and economic losses.</p><p><strong>Main body: </strong>Our study explores consumer behavior within the fast-food industry, highlighting its role in shaping responses to E. coli outbreaks. Also, it examines how increased awareness of food safety risks has influenced consumer decisions, such as adopting hygienic practices and preferring establishments that prioritize food safety. Furthermore, the study investigates the contribution of poor fast-food preparation practices-such as undercooking and cross-contamination-to the spread of E. coli and emphasizes the critical need for improved hygiene awareness among fast-food workers. We analysed notable case studies involving E. coli outbreaks linked to fast-food chains, and subsequently identified gaps in industry practices and consumer behavior that exacerbate the risk of foodborne illnesses. This emphasizes the importance of preventive measures, including industry-driven reforms such as enhanced food handling protocols and consumer education programs, to mitigate future outbreaks.</p><p><strong>Conclusions: </strong>This study aims to provide evidence-based insights into the shared responsibility of fast-food establishments and consumers in reducing the prevalence of E. coli infections. By addressing gaps in hygiene awareness and preparation practices, the findings emphasize the potential for collaborative efforts to strengthen public health outcomes and prevent further outbreaks.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"27"},"PeriodicalIF":3.6,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143493855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility and usability of a dengue NS1 rapid diagnostic as a self-test.","authors":"Nurfatihah Zulkifli, Naim Che-Kamaruddin, Atiqah Hazan, Tan Kim-Kee, Sivalingam Rajagopal, Sazaly AbuBakar","doi":"10.1186/s41182-025-00705-9","DOIUrl":"10.1186/s41182-025-00705-9","url":null,"abstract":"<p><strong>Background: </strong>Early detection of dengue fever is pivotal to help differentiate against other febrile illnesses, especially in the dengue-endemic regions. Currently, febrile patients would have to go to the healthcare facility to get tested for dengue. A diagnostic approach that empowers febrile persons to perform their own tests is needed. Here, we evaluated the utility and the usability of the dengue NS1 rapid diagnostic test and whether it could be accepted as a home self-test. A lateral flow immunochromatography test (ICT) using DENV NS1 was converted to a possible self-test kit by providing the kit with a test device, an alcohol swab, a lancet, a disposable dropper, an assay buffer, and a test manual.</p><p><strong>Methods: </strong>Twenty volunteers were recruited for this study. The participants performed the self-test under the observation of trained observers who recorded if any procedural error was committed. The results of each test were interpreted by the participants using a given interpretation table.</p><p><strong>Results: </strong>Ninety-five percent (95%) of the study participants found the instruction manual was easy to follow and 70% felt the test kit was easy to use. Additionally, 80% of the participants successfully obtained the expected results. A majority (80%) would consider using the test kit if needed and would recommend it to family members and friends. Seventy percent (70%) of the participants, most of whom with monthly income of less than USD417, were willing to pay less than USD2 for the test kit.</p><p><strong>Conclusion: </strong>Findings from the study suggested that a self-test diagnostic for dengue fever is highly acceptable and, hence, could be a viable approach for the early detection of the infection. Trial registration MRECID.NO: 2022628-11345.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"28"},"PeriodicalIF":3.6,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143493870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global, regional, and national trends in chronic kidney disease burden (1990-2021): a systematic analysis of the global burden of disease in 2021.","authors":"Jiaxi Chen, Miao Deng, Rubin Zheng, Yanjin Chen, Wenyi Pang, Ziyang Zhang, Zhouke Tan, Zhixun Bai","doi":"10.1186/s41182-025-00703-x","DOIUrl":"10.1186/s41182-025-00703-x","url":null,"abstract":"<p><strong>Background: </strong>Chronic kidney disease (CKD) is a global health challenge with diverse etiologies. However, research on the incidence trends of CKD attributable to specific causes remains limited, and the incidence and mortality rates vary across regions. This study aims to identify the patterns and temporal trends of CKD incidence, providing valuable information for the development of targeted prevention strategies and interventions.</p><p><strong>Methods: </strong>CKD data from the 2021 Global Burden of Disease Study (1990-2021) were analyzed by sex, region, country, cause, and Socio-demographic Index (SDI). Disease burden was assessed using age-standardized incidence (ASIR), mortality rates (ASMR), and estimated annual percentage changes (EAPC). Decomposition analysis evaluated population aging, growth, and epidemiological impacts. The autoregressive integrated moving average (ARIMA) model was used to predict the burden of CKD from 2021 to 2031, and the age-period-cohort (APC) model was employed to assess the effects of age, time, and cohort. Health inequality was analyzed using Slope Index of Inequality (SII) and Concentration Index (CI).</p><p><strong>Results: </strong>In 2021, Saudi Arabia had the highest ASIR, while Mauritius had the highest mortality. China and India contributed the most cases and deaths. ARIMA forecasts CKD cases will rise to 22.21 million and deaths to 1.81 million by 2031. Epidemiological changes drove incidence growth in medium SDI regions and mortality in high SDI regions. EAPC correlated with ASIR and ASMR. APC analysis showed incidence peaked between 70-80 years, with earlier cohorts facing higher risks. Unknown causes, type 2 diabetes, and hypertension were the leading CKD etiologies. From 1990-2021, health inequality in CKD incidence and mortality worsened, especially in high SDI regions, where the mortality CI shifted from 0.05 to - 0.09.</p><p><strong>Conclusions: </strong>This study estimated the temporal trends of CKD incidence and mortality globally, as well as at the national and regional levels, from 1990 to 2021. It was observed that countries with higher socio-demographic index (SDI) exhibited unfavorable trends, suggesting that these countries should develop more targeted and specific strategies to address the growing burden of CKD.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"26"},"PeriodicalIF":3.6,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11843816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A dynamic journey of comprehensive school health policy implementation in response to the COVID-19 pandemic in Lombok, Indonesia.","authors":"Cut Warnaini, Abiyyu Didar Haq, Hamsu Kadriyan, Fumiko Shibuya, Jun Kobayashi","doi":"10.1186/s41182-025-00690-z","DOIUrl":"10.1186/s41182-025-00690-z","url":null,"abstract":"<p><strong>Background: </strong>Coronavirus disease 2019 (COVID-19) pandemic in March 2020 led to new restrictive policies in several countries, including Indonesia. The comprehensive school health (CSH) framework provides overall guidance for interventions most effective in achieving specific outcomes related to health, nutrition, and education, and creating CSH programmes that account for the main contextual variations in Indonesian communities and schools is important. This study aimed to clarify how school health-related policies made before and after the COVID-19 pandemic responded to COVID-19 control measures on Lombok Island, Indonesia.</p><p><strong>Method: </strong>This was a qualitative observational analytic study. Researchers reviewed and analysed school health policy, held separate confirmation discussions and interviews with stakeholders and key informants, and observed policy implementation at public and private schools in Mataram.</p><p><strong>Results: </strong>The analysis found weaknesses and opportunities. Weakness included lack of guidelines, comprehensive planning, inconsistent hierarchy of roles and responsibilities, and social and cultural barriers. Opportunities included the importance of funding for consistent CSH implementation, monitoring and evaluation system, implementation between public and private schools, and decentralisation. Positive findings included CSH policy integration into teaching and learning activities, regular healthy school competition program, teachers as role models, existing coordination and distribution of responsibilities between relevant stakeholders, and authorising schools to make needed adjustments. Factors influencing school health efforts included curriculum, school organisation, personal ethos, and healthcare provider partnerships. To effectively promote school health efforts, schools must assess existing health problems within the school environment and surroundings, organisational structure and capabilities including knowledge and skills, commitment, and leadership aspects.</p><p><strong>Conclusion: </strong>The COVID-19 pandemic has prompted the implementation of CSH policies in schools of Lombok Island, demonstrating flexibility and dedication to student welfare. Despite confusion due to changing regulations, collaboration with local health organisations and community support has resulted in effective policy implementation.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"25"},"PeriodicalIF":3.6,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11841219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between paternal smoking behaviour and birth outcomes based on a comic booklet intervention for preventing second-hand smoke exposure to non-smoking pregnant women in Indonesia: a follow-up randomised controlled trial.","authors":"Kimiko Inaoka, Citra Gabriella Mamahit, Ishak Halim Octawijaya, Windy Mariane Virenia Wariki, Erika Ota","doi":"10.1186/s41182-025-00701-z","DOIUrl":"10.1186/s41182-025-00701-z","url":null,"abstract":"<p><strong>Background: </strong>Although the harmfulness of second-hand smoke (SHS) exposure to foetuses is well-established, literature reporting foetal outcomes in experimental studies is limited. This follow-up study on preventing SHS exposure among non-smoking Indonesian pregnant women at home was based on a randomised controlled trial involving the provision of comic booklets with stickers to couples. This trial examined differences in the birth outcomes of participating couples between the experimental and control groups, factors associated with paternal smoking behaviour, and association between birth outcomes and paternal-related outcomes.</p><p><strong>Methods: </strong>In total, 197 neonates of 286 couples who participated in an original trial were included. This study compared birth outcomes between participating couples using a comic booklet with stickers to reduce SHS exposure at home during pregnancy as the intervention. Pearson Chi-square tests were conducted to investigate significant differences in neonate sexes between the experimental and control groups. Independent sample t-tests were used to check for significant differences in birth outcome data between the experimental and control groups. A multiple regression analysis was applied to test the correlation between paternal smoking behaviour and the birth outcomes.</p><p><strong>Results: </strong>The gestational age in the experimental group was longer than the age in control group (mean difference = 0.373, Cohen's d = 0.291, 95% CI [0.010-0.57], p-value = 0.048). Pregnant women's avoidance of SHS strongly influenced paternal smoking behaviour in both the experimental group (b = 0.559, 95% CI [1.175-2.109], p-value < 0.001) and the control group (b = 0.429, 95% CI [0.675-1.567], p-value < 0.001). No associations were observed between birth and paternal behaviour outcomes.</p><p><strong>Conclusions: </strong>The neonates' gestational ages were greater in the experimental group than in the control group because of our intervention effect; pregnant women's avoidance of SHS strongly influenced paternal smoking behaviour in both groups. Thus, the comic booklet intervention for smoking fathers with non-smoking pregnant partners helped reduce the risk of foetal developmental disorders. Couple-based interventions should be actively integrated into health worker strategies to effectively mitigate second-hand smoke exposure among pregnant women. Trial registration This study was registered in the UMIN Clinical Trials Registry under the registration number UMIN000035423 (01/02/2019).</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"23"},"PeriodicalIF":3.6,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11837665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Another potential etiology for cardiac manifestation after snakebite.","authors":"Yoshihiro Aoki, Chris Smith, Koya Ariyoshi","doi":"10.1186/s41182-025-00709-5","DOIUrl":"10.1186/s41182-025-00709-5","url":null,"abstract":"<p><p>This letter discusses the possibility of Takotsubo cardiomyopathy (TTC) as an alternative diagnosis in a recently reported case of acute myocardial infarction following a hump-nosed viper bite. The patient's presentation, including delayed chest tightness, elevated troponin, ECG changes, and normal coronary arteries, coupled with complete recovery within 3 months, strongly suggests TTC. Multiple case reports have documented the association between snakebites and TTC, with proposed pathophysiological mechanisms including sympathetic surge from pain and stress, direct cardiotoxic effects of venom, and inflammatory mediators during envenomation. The excessive catecholamine response may trigger transient cardiac dysfunction characteristic of TTC. Recognizing TTC as a potential complication of snakebites has important clinical implications, as its management and prognosis differ from acute coronary syndrome. Understanding this association may enhance diagnostic approaches and treatment strategies in similar cases, particularly when normal coronary arteries and complete cardiac recovery are observed.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"22"},"PeriodicalIF":3.6,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11837627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asymptomatic malaria infections and associated risk factors in malaria-eliminating settings of Nong District, Savannakhet Province, Lao People's Democratic Republic.","authors":"Taofic Bouwe, Daisuke Nonaka, Philippe Buchy, Parita Hansana, Boualam Khamlome, Vixayyang Chayvangmanh, Noudéhouénou Credo Adelphe Ahissou, Keobouphaphone Chindavongsa, Tiengkham Pongvongsa, Virasack Banouvong, Moritoshi Iwagami","doi":"10.1186/s41182-025-00702-y","DOIUrl":"10.1186/s41182-025-00702-y","url":null,"abstract":"<p><strong>Background: </strong>As the Lao People's Democratic Republic is nearing malaria elimination, asymptomatic malaria infections remain a challenge to address. Control measures focusing on symptomatic persons do not effectively work for asymptomatic infections which often go undetected by conventional diagnostic tools. It is therefore crucial to understand the burden of asymptomatic malaria for tailored interventions to eliminate the disease. This study assessed the prevalence of asymptomatic malaria infections with associated risk factors in an endemic district of Savannakhet province.</p><p><strong>Methods: </strong>In March 2024, a cross-sectional study was conducted in three villages of Nong District. Blood samples were collected from the fingertips of the participants for Plasmodium parasite identification using microscopy and Loop-mediated Isothermal Amplification (LAMP); those aged 13 years and above were also interviewed. Mann-Whitney U test and Fisher's exact test were performed to compare the medians of different age and temperature groups and determine the association between predictor variables and outcome variables respectively.</p><p><strong>Results: </strong>A total of 622 individuals participated in this survey; Plasmodium parasites were detected in 2.1% (13/622) of participants. The prevalence of asymptomatic malaria was 1.8% (11/622). Plasmodium vivax accounted for 15.4% (2/13) of all positive cases. The remaining species could not be identified. Farmers aged 15 years and above accounted for 81.8% of the asymptomatic infections. Ninety percent (90%) of the participants used bed nets in the village. Among interviewed participants, 23.6% reported not using mosquito bed nets in the forest; 21.3% of the participants who had been to the forest were nighttime forest workers.</p><p><strong>Conclusions: </strong>This study revealed a prevalence of 1.8% of asymptomatic malaria infections in the study areas with the majority of the infections clustered among farmers, and an important proportion of these populations not using protective measures in the forest. These findings showed that malaria reservoirs are notable with a lack of use of protective measures, which could threaten malaria control and elimination efforts. Therefore, malaria elimination in Lao PDR by 2030 would need interventions targeting high-risk adult populations for screening with sensitive tools coupled with sensitization on protective measures and asymptomatic malaria.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"24"},"PeriodicalIF":3.6,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11841228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Susceptibility of Anopheles gambiae s.l. to the neonicotinoid insecticide clothianidin in eighteen sites located along the south-north transect of Benin.","authors":"Steve Zinsou Hougbe, Arthur Sovi, Koffi Koumodji, Minassou Juvénal Ahouandjinou, Zul-Kifl Affolabi, Linda Towakinou, Saïd Chitou, Andil Agbo-Ola, Filémon Tokponnon, David Mahouton Zoungbédji, Hermann Sagbohan, Casimir Kpanou, Germain Gil Padonou, Lamine Baba-Moussa, Razaki A Ossé","doi":"10.1186/s41182-025-00694-9","DOIUrl":"10.1186/s41182-025-00694-9","url":null,"abstract":"<p><strong>Background: </strong>The widespread resistance of malaria vectors to traditional neurotoxic insecticides has stimulated the search for new insecticide classes with novel modes of action. For that, the present study was designed to collect data on the susceptibility of field-collected Anopheles gambiae sensu lato (s.l.) to clothianidin, a neonicotinoid insecticide used in agriculture and that recently received WHO approval for use in indoor residual spraying.</p><p><strong>Methods: </strong>An. gambiae s.l. were collected as larvae and pupae from 18 sites located along the south-north transect of Benin, and reared to adulthood. Female mosquitoes aged 2-5 days were exposed to clothianidin-impregnated papers (2% weight by volume (w/v) of SumiShield™ 50WG dissolved in distilled water). Due to the delayed action of clothianidin, mortality was daily recorded over 7 days. Polymerase chain reaction was used to assess the molecular species composition in the An. gambiae s.l. complex and the frequency of knockdown resistance (kdr) and insensitive acetylcholinesterase (Ace-1^R) mutations.</p><p><strong>Results: </strong>Mortality rates of field-collected An. gambiae s.l. were very high (≥98%) between 2- and 7-day post-exposure, indicating full susceptibility to clothianidin. Molecular species identification revealed the presence of An. coluzzii (53.7%), An. gambiae sensu stricto (s.s.) (42.5%), and An. arabiensis (3.8%) in the An. gambiae s.l. complex. kdr and Ace-1^R mean frequencies were 84% (95% CI 82-86) and 3% (95% CI 2-4) in An. coluzzii, and 88% (95% CI 87-90) and 4% (95% CI 3-6) in An. gambiae s.s., respectively.</p><p><strong>Conclusions: </strong>Findings of the present study indicates that An. gambiae s.l. populations collected along the north-south transect of Benin remain susceptible to clothianidin. This broadens the portfolio of indoor residual spraying products that the national malaria control programme can deploy to better control pyrethroid-resistant populations of vectors.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"21"},"PeriodicalIF":3.6,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11816534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secondary sclerosing cholangitis: an unusual presentation of leptospirosis.","authors":"Tilan Aponso, W M D A S Wanninayake, I P Wijesinghe, Nethma Jayasekara, Waruna Iddamalgoda, W M M A Wanasinghe","doi":"10.1186/s41182-025-00700-0","DOIUrl":"10.1186/s41182-025-00700-0","url":null,"abstract":"<p><p>Sclerosing cholangitis is a rare progressive cholestatic disease that is classified as secondary sclerosing cholangitis when it is caused by an identifiable cause. Sclerosing cholangitis has been linked to infections like COVID-19 and parasitic infections like Clonorchis sinensis and Ascaris lumbricoides. However, leptospirosis has not been linked to sclerosing cholangitis in the medical literature. In this article, we report a 37-year-old gentleman who was diagnosed with leptospirosis, worsened by painless cholestasis, while he was improving from leptospirosis. Magnetic resonance cholangiopancreatography revealed multiple short-segment biliary strictures, segmental dilatation, and mural irregularities in both intrahepatic ducts confirming the diagnosis of sclerosing cholangitis. After ruling out other potential causes and considering the initial presentation during a leptospirosis infection, we concluded that leptospirosis caused secondary sclerosing cholangitis. We report this as the first case of secondary sclerosing cholangitis in a leptospirosis patient without renal, respiratory, or cardiac complications, emphasizing the importance of ruling out this cause in a leptospirosis patient with persistent cholestasis.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"20"},"PeriodicalIF":3.6,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11818175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}