Tropical Medicine and Health最新文献

{"title":"Quality and safety requirements for pharmacy-based vaccination in resource-limited countries.","authors":"Kidanemariam G/Michael Beyene, Melaku Tileku Tamiru","doi":"10.1186/s41182-025-00698-5","DOIUrl":"10.1186/s41182-025-00698-5","url":null,"abstract":"<p><p>Pharmacy-based vaccination (PBV) programs have proven to be a promising strategy for improving vaccination coverage, particularly in resource-limited countries. These programs increase accessibility and convenience, increase vaccination rates, and benefit vulnerable populations. However, successful implementation requires addressing gaps in regulatory oversight, pharmacists training, inter-professional collaboration, and public awareness. With proper regulatory frameworks, advocacy, enhanced training programs, public education, and establishment of well-designed database, PBV can achieve outcomes comparable to high-resource settings. This commentary aims to inform stakeholders and offer practical recommendations to minimize risks while leveraging its benefits.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"19"},"PeriodicalIF":3.6,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11800504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revealing viral hepatitis epidemiology in the Democratic Republic of Congo: insights from yellow fever surveillance reanalysis.","authors":"Patrick Mukadi-Kakoni, Yannick Munyeku-Bazitama, Gracia Kashitu-Mujinga, Marguerite Manwana-Pemba, Niclette Zenga-Bibi, Patient Okitale-Talunda, Christelle Mbelu-Kabongo, Fleurette Domai-Mbuyakala, Elisabeth Pukuta-Simbu, Pierre Mutantu-Nsele, Yoshinao Kubo, Sheila Makiala-Mandanda, Steve Ahuka-Mundeke, Koya Ariyoshi, Jean-Jacques Muyembe-Tamfum","doi":"10.1186/s41182-025-00687-8","DOIUrl":"10.1186/s41182-025-00687-8","url":null,"abstract":"<p><strong>Background: </strong>Yellow fever surveillance systems are designed to identify cases of acute febrile jaundice, a clinical syndrome used to monitor the emergence of yellow fever outbreaks. However, this syndrome has diverse etiologies, particularly viral hepatitis. This study investigates the seroepidemiology of viral hepatitis A (HAV), B (HBV), C (HCV), and E (HEV) among cases initially suspected to be yellow fever, aiming to elucidate the epidemiology of viral hepatitis in the Democratic Republic of Congo (DRC) and provide insights for improving public health interventions.</p><p><strong>Methods: </strong>A retrospective cross-sectional study was conducted using serum samples collected between 2017 and 2018 through national yellow fever surveillance in the DRC. Samples from individuals testing negative for yellow fever were tested for IgM antibodies against HAV, HBc, HCV, and HEV and HBs antigen using validated ELISA kits. Acute HBV infection was defined by both HBc IgM and HBs antigen positivity. Multivariable logistic regression was used to assess the association of demographic, geographic, and environmental factors with each hepatitis type.</p><p><strong>Results: </strong>Among 1239 participants (58.8% male; median age: 16 years), seroprevalence was 16.1, 11.2, 5.0, and 3.1% for HAV, HBV, HCV and HEV, respectively. HAV prevalence was highest in the youngest age group and rural residents. In contrast, the youngest group was most protected from HBV. HCV prevalence was highest in the oldest age groups. HEV exhibited higher prevalence during the dry season and in a humid subtropical climate. Several provinces were identified as hotspots of HAV, HCV and HEV.</p><p><strong>Conclusions: </strong>Viral hepatitis is a major cause of acute febrile jaundice in the DRC with notable geographic and seasonal trends. National yellow fever surveillance is a valuable resource for understanding hepatitis epidemiology, though careful interpretation is necessary. Tailored interventions are required for mitigating the burden of viral hepatitis in each province.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"17"},"PeriodicalIF":3.6,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11800490/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social network analysis of key stakeholders in Brucellosis prevention in Western Iran.","authors":"Meysam Behzadifar, Mohammad Yarahmadi, Ahad Bakhtiari, Sahar Kargar, Saeed Shahabi, Samad Azari, Mariano Martini, Masoud Behzadifar","doi":"10.1186/s41182-025-00693-w","DOIUrl":"10.1186/s41182-025-00693-w","url":null,"abstract":"<p><strong>Background: </strong>Brucellosis remains a persistent public health challenge in Iran, particularly in rural regions such as Lorestan province, due to systemic, economic, and cultural barriers. Effective disease control requires multisectoral collaboration among stakeholders. This study aimed to map the stakeholder network involved in brucellosis prevention in Lorestan province, identify gaps in coordination, and provide actionable recommendations for improving control strategies.</p><p><strong>Methods: </strong>This cross-sectional study employed social network analysis (SNA) to explore the relationships among key stakeholders in brucellosis prevention. Data were collected through a structured questionnaire administered to 75 experts from various sectors, including health, veterinary, agriculture, and non-governmental organizations. The SNA evaluated network density, clustering coefficient, and centrality metrics to determine the levels of collaboration and influence among stakeholders.</p><p><strong>Results: </strong>The analysis revealed a moderately dense network (density: 0.2745; clustering coefficient: 0.2839) with central roles played by the Veterinary Organization of Lorestan Province, Lorestan University of Medical Sciences, and the Ministry of Agriculture. These organizations exhibited high levels of influence, support, and interest in brucellosis prevention. However, limited involvement of community-based organizations and environmental agencies was identified, highlighting a critical gap in grassroots engagement. Fragmented coordination was particularly evident in rural areas, where traditional livestock practices, inadequate veterinary services, and the consumption of unpasteurized dairy products perpetuate disease transmission. Economic constraints, such as the high cost of vaccines, along with limited public awareness, further hinder effective control efforts.</p><p><strong>Conclusions: </strong>Brucellosis prevention in Lorestan province requires a comprehensive, multisectoral approach. The adoption of a One Health framework can improve collaboration among stakeholders, enhance resource allocation, and address systemic barriers. Community engagement and intersectoral coordination are essential for improving public awareness and compliance with preventive measures. These findings provide a foundation for developing a National Brucellosis Control Program and inform strategies to mitigate zoonotic diseases in similar high-risk regions.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"18"},"PeriodicalIF":3.6,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11800574/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of urinary tract infections in the Middle East and North Africa, 1990-2021.","authors":"Fatemeh Amiri, Saeid Safiri, Reza Aletaha, Mark J M Sullman, Kamaleddin Hassanzadeh, Ali-Asghar Kolahi, Shahnam Arshi","doi":"10.1186/s41182-025-00692-x","DOIUrl":"10.1186/s41182-025-00692-x","url":null,"abstract":"<p><strong>Objective: </strong>This research reports the incidence, mortality, and disability-adjusted life years (DALYs) associated with urinary tract infections (UTIs) in the Middle East and North Africa (MENA) region, stratified by sex, age, and Socio-demographic Index (SDI) from 1990 to 2021.</p><p><strong>Methods: </strong>Data were sourced from the Global Burden of Disease 2021 study, encompassing all 21 countries in the region. Metrics such as absolute counts, age-standardised rates, and percentage changes from 1990 to 2021 are presented with 95% uncertainty intervals (UIs).</p><p><strong>Results: </strong>In 2019, the MENA region recorded an incidence rate of 4,033.4 per 100,000 (95% UIs: 3,553.7-4,548.7) and 7,687 deaths (95% UIs: 6,663-8,969). The DALY rate was 41.3 per 100,000 (95% UIs: 36.1-47.2), which was highest among older adults, reaching a peak in the 80-89 age range, and increasing with age, particularly from the 50 + age groups. A non-linear relationship was identified between the burden of UTIs and the SDI, with higher-than-expected rates in lower SDI countries such as Syria and Lebanon.</p><p><strong>Conclusion: </strong>Despite a substantial increase in the total number of UTI cases and DALYs in the region from 1990 to 2021, the age-standardised rates remained stable. The larger burden in lower SDI countries highlights the urgent need for targeted public health interventions. Improving healthcare access and antibiotic stewardship is crucial to mitigating the growing burden of UTIs, particularly among older populations in the region.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"16"},"PeriodicalIF":3.6,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11796260/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elucidating the knowledge, attitude, and stigma associated with tuberculosis: a community based descriptive study in Wau and Jur River, South Sudan.","authors":"Peter Michael Marin, Morten Tryland, Musso Munyeme, Ambrose Samuel Jubara, Enock Matovu, Peter Waiswa, Javier Sanchez Romano, Francis Mutebi, David Onafruo, Estella Kitale, Esther Sabbath, Kayla J Buhler, Clovice Kankya","doi":"10.1186/s41182-025-00696-7","DOIUrl":"10.1186/s41182-025-00696-7","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) is a major public health problem in South Sudan. Inadequate knowledge, negative attitudes and perceived stigma may complicate the prevention efforts. This study describes knowledge, attitude, and stigma associated with TB among communities in Wau and Jur River, South Sudan.</p><p><strong>Methods: </strong>From March to May 2023, a cross-sectional study was conducted among 352 community members randomly selected from residential blocks. A validated structured questionnaire was used to collect the required data. Descriptive, bivariate and multivariate analyses were performed.</p><p><strong>Results: </strong>Out of 352 respondents, 51% (n = 180) were males and 49% (n = 172) were females. Majority 227 (64.5%) had poor knowledge about TB, meanwhile hearing about TB, age and level of education were associated factors. Fear of having TB was the major negative attitude (57.1%; n = 218), and most of the respondents (n = 327; 92.9%) had a perceived stigma towards TB, voicing that they disliked drinking or eating with people with TB and/or felt uncomfortable and kept their distance from people with TB.</p><p><strong>Conclusions: </strong>Communities have little knowledge, negative attitude and perceived stigma towards people with TB. Hence, tailored health messages using local languages, training of community volunteers to reach villages without accessibility and communication network are essential to improve TB prevention and control in South Sudan.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"15"},"PeriodicalIF":3.6,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11796033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early discharge and international air transport of a traveler with exacerbating comorbidities and pneumomediastinum: a case report.","authors":"Miho Akimoto, Soichiro Saeki, Yuki Kiyomoto, Hirosane Takeshima, Naofumi Higuchi, Takako Mori, Yasuyo Osanai, Chihaya Hinohara, Takeshi Inagaki","doi":"10.1186/s41182-025-00684-x","DOIUrl":"10.1186/s41182-025-00684-x","url":null,"abstract":"<p><strong>Background: </strong>Air transport for medically complex patients presents unique challenges, particularly without specific guidelines for conditions such as pneumomediastinum or medical devices like peripherally inserted central catheters (PICC lines). Although organizations such as the Aerospace Medical Association (AsMA) and the International Air Transport Association (IATA) provide general recommendations for medical air travel, these guidelines often lack the precision required to address such complex clinical scenarios. Consequently, healthcare teams frequently face difficult decisions under constraints of time and resources, navigating the interplay of patient safety, autonomy, and logistical considerations.</p><p><strong>Case presentation: </strong>This case involves a 30-year-old American woman with type 2 diabetes, obesity, and a recent history of pancreaticoduodenectomy, who was hospitalized in Japan with cellulitis and incidentally diagnosed with pneumomediastinum. She was treated with intravenous antibiotics and central venous nutrition administered via a PICC line. However, she requested an early discharge to return to the United States for family and financial reasons. Her travel insurer declined coverage, citing potential risks associated with pneumomediastinum. Ultimately, the patient discharged herself against medical advice; the PICC line was removed, and she transitioned to oral antibiotics for her journey home.</p><p><strong>Conclusion: </strong>This case highlights the complexities of patient preferences, medical risks, and insurance limitations when evaluating air travel safety. The absence of specific guidelines for conditions such as pneumomediastinum and the use of medical devices highlights the need for condition-specific protocols. Effective communication and customized documentation, including modifications to the \"Against Medical Advice\" form proved essential in addressing both patient autonomy and the responsibilities of healthcare providers.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"14"},"PeriodicalIF":3.6,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143075558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emergence and expansion of dengue in Paltas: possible implications of the COVID-19 pandemic and climatic variations.","authors":"Beatriz Quintero, Angélica X Ramón-Ochoa, Solbey Morillo-Puente, Daniel A Tenezaca-Ramón, Alejandra S Cevallos-Naranjo","doi":"10.1186/s41182-025-00689-6","DOIUrl":"10.1186/s41182-025-00689-6","url":null,"abstract":"<p><strong>Introduction: </strong>Dengue is one of the most widespread arboviruses in Latin America and is now affecting areas previously free of transmission. The COVID-19 pandemic and climatic variations appear to have affected the incidence of the disease, abundance of vectors and health programs related to dengue in some countries.</p><p><strong>Objective: </strong>To analyze the epidemiology of dengue in Paltas, Ecuador (2016-2022), compare the periods before and during the COVID-19 pandemic, examine entomological reports and discuss the possible implications of the COVID-19 pandemic and climatic variations.</p><p><strong>Methodology: </strong>In this observational, retrospective study, cases of dengue registered in the SIVE-Alert epidemiological surveillance system and the available larval indices were examined.</p><p><strong>Results: </strong>No autochthonous cases were reported before 2016. Between 2016 and 2022, 182 cases without warning signs were reported, mostly in women (51.1%), people ≥ 20 years (68.7%) and people living in urban areas (78.6%). During the COVID-19 pandemic, there was a significant decline in cases in urban areas, with displacement toward rural areas (p < 0.001). A clear pattern of dengue incidence was observed throughout the year, with a predominance (84.6%) in epidemiological weeks 16-39 (April-September), which coincided with the dry season in the region. In 2016 and 2018, larval rates were high in urban areas but decreased in 2019. Postpandemic incidence rates increased in urban and rural areas, even in areas without transmission of the disease.</p><p><strong>Conclusions: </strong>There is a clear pattern of incidence of dengue in the dry season in the region. After the 2016 outbreak, larval cases and rates decreased, suggesting the effectiveness of vector control before the COVID-19 pandemic. However, during the pandemic there was a resurgence in dengue with expansion in rural and urban areas. The increase in larval rates during the COVID-19 pandemic, even in dengue-free areas, is worrisome. A critical challenge in the control of mosquito breeding sites is climatic variations, which increase the need to reserve water for domestic use.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"12"},"PeriodicalIF":3.6,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11781008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of clinical and virological features in pediatric and adult dengue cases at Insein General Hospital during Myanmar's 2022 dengue season.","authors":"Htin Lin, Mya Myat Ngwe Tun, Yin Mon Wint Zin, Khin Theingi Myint, Win Kay Khine, Khine Mya Nwe, Aye Aye Thant, Thin Thin Shwe, Win Mar, Khin Sandar Aye, Khaing Moe Aung, Yuki Takamatsu, Wah Wah Aung, Yi Yi Kyaw, Takeshi Urano, Kouichi Morita, Hlaing Myat Thu","doi":"10.1186/s41182-025-00688-7","DOIUrl":"10.1186/s41182-025-00688-7","url":null,"abstract":"<p><strong>Background: </strong>Myanmar is one of the countries in Southeast Asia where serious dengue outbreaks occur and Yangon is among the regions with the highest number of cases in the country. Many infections including dengue are common in Yangon during the rainy season, and co-infections may also occur. Adults are more likely than children to experience co-infections of dengue and other diseases. Although pediatric dengue has been studied in Yangon for decades, research on adult dengue is scant. Therefore, this study compared the clinical and virological characteristics of pediatric and adult dengue cases in Yangon.</p><p><strong>Methods: </strong>This cross-sectional study was conducted at Insein General Hospital in Yangon, Myanmar, from June to September 2022. We recruited 221 suspected dengue patients (134 children and 87 adults), with or without other diseases, and tested their dengue serological markers using a serological method and their dengue virus (DENV) serotypes using conventional RT-PCR. Chi-squared and Fisher's exact tests were conducted to assess significance.</p><p><strong>Results: </strong>The dengue non-structural protein-1 antigen (NS1Ag) positivity was 37% in children and 32% in adults. DENV serotypes were identified in 80% of NS1Ag-positive patients. Among NS1Ag-positive cases, the DENV-1 serotype predominated (67%), followed by DENV-2 (17%), DENV-3 (9%), DENV-4 (5%), and mixed DENV-1 and DENV-2 (2%) serotypes. Shock was observed in 14% of children and 3% of adults. Anti-dengue IgG antibody positivity was positively correlated with dengue shock. Three pediatric dengue cases (6%) also had other infections including bronchiolitis, ear infection, and diarrhea. Seven adult dengue cases (25%) also had other diseases including advanced HIV infection, severe pneumonia, tonsillitis, thyroid disease, cholecystitis, drug poisoning, and thalassemia.</p><p><strong>Conclusion: </strong>The serotype distribution and clinical presentations of pediatric and adult dengue cases were not significantly different, but adults were more likely to have dengue together with other diseases than children. This study provides information for the better management of febrile children and adults in hospital settings and provides a foundation for nationwide epidemiological studies on dengue serotypes and modifications of the national guidelines for dengue management in Myanmar.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"13"},"PeriodicalIF":3.6,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of flavivirus RNA stability and infectivity in various water environments.","authors":"Yuka Sano, Hawraa Al-Alawi, Misao Himeno, Ryuichi Majima, Kazumi Haga, Myo Thura Kyaw, Satoshi Taniguchi, Meng Ling Moi","doi":"10.1186/s41182-025-00686-9","DOIUrl":"10.1186/s41182-025-00686-9","url":null,"abstract":"<p><strong>Introduction: </strong>Flaviviruses such as dengue virus (DENV), Zika virus (ZIKV), Japanese encephalitis virus (JEV), and Yellow fever virus (YFV) are mosquito-borne RNA viruses causing major public health threats in major parts of the world. While DENV and ZIKV have been detected in urine samples, data on the presence and stability of flaviviruses in the water environment are limited.</p><p><strong>Methods: </strong>In this study, we determined the stability and infectivity of flavivirus in different water environments by utilizing RT-qPCR and plaque assay to explore the feasibility of environmental detection and surveillance of flaviviruses.</p><p><strong>Results: </strong>Viral RNA could be detected for up to 49-days, at 4 °C, 25 °C and 37 °C temperatures, and infectious particles could be detected for up to 7 days. While our findings showed that flaviviral RNA has higher stability and better detection rates at lower temperatures, the infectious capacity of flaviviruses was comparatively short at 7 days.</p><p><strong>Conclusions: </strong>Our results indicate that flaviviruses retains limited infectivity in general water environments and highlight the feasibility of detection and surveillance in various epidemiologic and environmental settings.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"11"},"PeriodicalIF":3.6,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and pattern of skin disorders among children living in orphanages in Fayoum and Giza governorates, Egypt.","authors":"Noha Ezzat Mohamed, Wafaa Yousif Abdel-Wahed, Shimaa Mohammed Gomaa, Mai Ashraf Hosny","doi":"10.1186/s41182-025-00685-w","DOIUrl":"10.1186/s41182-025-00685-w","url":null,"abstract":"<p><strong>Background: </strong>Childhood is a crucial period that shapes a person's growth and development. For orphans, a lack of familial support affects their upbringing, making orphanages crucial for care. Children living in orphanage centers are vulnerable to several conditions, including dermatological disorders, due to factors such as malnutrition, overcrowding, and poor hygiene. The current study was carried to determine the prevalence and patterns of skin disorders among orphan children in Egypt, and to identify associated risk factors among orphans in Egypt.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 415 children aged 1-18 years living in orphanage centers in Fayoum and Giza governorates, Egypt.</p><p><strong>Results: </strong>Among the children, 77.1% had at least one skin disorder, with noninfectious conditions being more prevalent than infectious conditions (67.4 vs. 24.3%). The most common noninfectious conditions were dermatitis/eczema, pigmentary disorders, skin appendage disorders, and psycho-cutaneous issues. Fungal infections were the most common infectious condition. There was a significant relationship between hygiene and the type of skin disorder.</p><p><strong>Conclusion: </strong>The prevalence of skin diseases in orphanages in Egypt is relatively high and is dominated by noninfectious skin diseases, and the prevalence of psycho-cutaneous disorders is high among these children. Comprehensive care strategies focusing on improving hygiene and emotional support and preventing abuse are essential for reducing the incidence of skin disorders and enhancing the overall health of orphaned children.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":"53 1","pages":"10"},"PeriodicalIF":3.6,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11744936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}