Thermal Medicine最新文献_第2页

Role of Hsp70-Bag3 Complex for Proteotoxicity Hsp70-Bag3复合物在蛋白质毒性中的作用

Thermal Medicine Pub Date : 2022-10-01 DOI: 10.3191/thermalmed.38.65

Y. Tabuchi, Tatsuya Yunoki

引用次数: 0

Impacts of Heat Shock Protein 40/J-domain Proteins on Cancer Progression and p53 Activity 热休克蛋白40/ j结构域蛋白对癌症进展和p53活性的影响

Thermal Medicine Pub Date : 2022-07-01 DOI: 10.3191/thermalmed.38.33

A. Kaida, T. Iwakuma

引用次数: 0

Heating Characteristics of Small Rectangular Resonant Cavity Applicator with Non-invasive Temperature Measurement Function 具有非侵入式测温功能的小矩形谐振腔涂抹器的加热特性

Thermal Medicine Pub Date : 2022-07-01 DOI: 10.3191/thermalmed.38.51

N. Hayashi, Kazuo Kato, Y. Shindo, Y. Iseki

引用次数: 1

HSP40 Family Member DNAJA1 Promotes Cancer Metastasis through Interaction with Mutant p53 HSP40家族成员DNAJA1通过与p53突变体相互作用促进肿瘤转移

Thermal Medicine Pub Date : 2022-03-15 DOI: 10.3191/thermalmed.38.30

K. Ohtsuka

引用次数: 0

Antitumor Activity of Non-thermal Atmospheric Pressure Plasma and Synergistic Effects of Hyperthermia 非热大气压血浆的抗肿瘤活性及热疗的协同作用

Thermal Medicine Pub Date : 2022-03-15 DOI: 10.3191/thermalmed.38.1

T. Adachi

引用次数: 1

Anti-Tumor Effect of the Combinational Treatment with Erastin and Cerastrol Erastin与Cerastrol联合治疗的抗肿瘤效果

Thermal Medicine Pub Date : 2022-03-15 DOI: 10.3191/thermalmed.38.28

K. Ohtsuka

引用次数: 0

Mode of Tumor Necrosis Induction in vivo by Heat-generating Nanoparticles of Magnetite Cationic Lipid Composite Particles Dispersing toward Neighbor Naïve Tumor Zone and its Therapeutic Use 磁性阳离子脂质复合热纳米颗粒向邻近Naïve肿瘤区分散诱导肿瘤坏死的体内模式及其治疗应用

Thermal Medicine Pub Date : 2022-03-15 DOI: 10.3191/thermalmed.38.19

T. Morino, H. Takase, N. Kawai, T. Nagai, T. Etani, T. Naiki, T. Yasui

引用次数: 0

Heating Characteristics of Prototype Knee Rehabilitation System Using Rectangular Resonant Cavity Applicator 基于矩形谐振腔的膝关节康复系统原型加热特性研究

Thermal Medicine Pub Date : 2021-12-15 DOI: 10.3191/thermalmed.37.131

N. Hayashi, Kazuo Kato

{"title":"Heating Characteristics of Prototype Knee Rehabilitation System Using Rectangular Resonant Cavity Applicator","authors":"N. Hayashi, Kazuo Kato","doi":"10.3191/thermalmed.37.131","DOIUrl":"https://doi.org/10.3191/thermalmed.37.131","url":null,"abstract":": We designed and prototyped a small rectangular resonant cavity applicator system for thermal treatment of knee osteoarthritis, and discussed its usefulness from both results of computer simulations and heating experiments. The authors had proposed a deep knee joint thermal rehabilitation system using a cylindrical resonant cavity, and demonstrated its usefulness from the results of agar phantom heating experiments and clinical heating experiments by volunteers. However, the area of the leg placed inside the cavity was wide when using the cylindrical cavity, so the healthy calf and thigh, which are not the targeted tissues, were also slightly heated. Therefore, in the present study, we clarified the possibility of deep thermal treatment with higher safety by changing the cylindrical shape of the resonant cavity to a compact rectangular shape. First, the dimensions and resonant frequency band of the rectangular cavity applicator were determined using the finite element method (FEM) ． Based on the numerical results, a heating system was prototyped, and heating experiments were conducted on a cylindrical agar phantom and a human leg-shaped agar phantom. Dimensions of the rectangular resonant cavity applicator are 300 mm in height, 350 mm in width and 200 mm in length. Heating experiments were conducted with a heating power of 30 W and a heating time of 10 minutes. As a result, it was confirmed that the central part of the cylindrical agar phantom was locally heated, and the temperature increase value was approximately 8.0 ° C. Furthermore, in the experiment which the leg-shaped agar phantom was heated, it was confirmed that only the knee joint was locally heated and no hot spots were generated in other areas. From these experimental results, it was concluded that the deep part of the knee joint could be safely and locally heated by using the rectangular resonant cavity applicator.","PeriodicalId":23299,"journal":{"name":"Thermal Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82593551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Temperature Distribution of Resonant Cavity Applicator for Thermal Rehabilitation Using 3D Printing 3D打印热修复共振腔应用器的温度分布

Thermal Medicine Pub Date : 2021-12-15 DOI: 10.3191/thermalmed.37.113

Y. Iseki, Shunsuke Kurosawa, Y. Shindo, Kazuo Kato

{"title":"Temperature Distribution of Resonant Cavity Applicator for Thermal Rehabilitation Using 3D Printing","authors":"Y. Iseki, Shunsuke Kurosawa, Y. Shindo, Kazuo Kato","doi":"10.3191/thermalmed.37.113","DOIUrl":"https://doi.org/10.3191/thermalmed.37.113","url":null,"abstract":"Osteoarthritis (OA) is one of the most common joint diseases. Thermotherapy, such as that using a microwave diathermy applicator, is widely used for OA. The deep tissue of a knee joint should be heated to 36 °C-38 °C for an effective thermotherapy. However, heating this deep region using a microwave diathermy applicator is challenging. Previously, we proposed a resonant cavity applicator to overcome these problems and confirmed its ability (heating experiments on bovine knees) to heat the deep region of a knee joint without physical contact. Furthermore, we proposed a method of temperature measurement using ultrasound images. In this method, the temperature distribution was measured using noninvasive image analysis. In a previous study, we found temperature measurement accuracy of ≤ 1.0 °C. In the present paper, we describe a temperature distribution using a 3D-printed knee model for treating OA. First, we created a 3D finite element model (FEM) of the knee and a 3D-printed knee model from 2D medical images. Second, we calculated temperature distributions in the FEM model and performed a heating experiment with a prototype of the heating system. Third, we performed positioning accuracy experiments to investigate the accuracy of our temperature measurement system comprising a robotic arm, 3D-printed knee model, and ultrasound diagnostics. Finally, we measured the temperature distribution inside the 3D-printed knee model from ultrasound images. The heating experiments confirmed that our proposed method could heat deep regions of a knee joint without any undesirable hotspot. Therefore, our results suggest that this method is useful for effective thermotherapy of OA.","PeriodicalId":23299,"journal":{"name":"Thermal Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80853724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-thermal Effects of Electromagnetic Waves and Its Application for Cancer Therapy 电磁波的非热效应及其在癌症治疗中的应用

Thermal Medicine Pub Date : 2021-12-15 DOI: 10.3191/thermalmed.37.142

T. Kondo, Koichi Ito, J. Miyakoshi

引用次数: 0