Microtechnologies for the New Millennium最新文献

{"title":"Defect luminescence in oxides nanocrystals grown by laser assisted techniques","authors":"J. Rodrigues, M. Soares, N. Santos, T. Holz, N. Ben Sedrine, C. Nico, A. Fernandes, A. Neves, F. Costa, T. Monteiro","doi":"10.1117/12.2178392","DOIUrl":"https://doi.org/10.1117/12.2178392","url":null,"abstract":"Wide band gap oxides, such as ZnO, SnO2 and ZrO2, are functional materials with a wide range of applications in several important technological areas such as those including lighting, transparent electronics, sensors, catalysis and biolabeling. Recently, doping and co-doping of oxides with lanthanides have attracted a strong interest for lighting purposes, especially among them nanophosphors for bioassays. Tailoring the crystalline materials physical properties for such applications often requires a well-controlled incorporation of dopants in the material lattice and a comprehensive understanding of their role in the oxides matrices. These undoped or intentionally doped oxides have band gap energies exceeding 3.3 eV at room temperature and are known to exhibit optically active centers that span from the ultraviolet to the near infrared region. Typically, by using photon energy excitation above the materials band gap, high quality undoped materials display narrow emission lines near the band edge due to free and bound-exciton recombination, as well as shallow donor-acceptor recombination pairs. Additionally, broad emission bands are often observed in these wide band gap hosts, hampering some of the desired physical properties for further applications. Recognizing and understanding the role of the dopant-related defects when deliberately introduced in the oxide hosts, as well as their influence on the samples luminescence properties, constitutes a matter of exploitation by the scientific community worldwide. In this work, we investigate the luminescence properties of undoped and lanthanide doped oxide materials grown by laser assisted techniques. Laser assisted flow deposition (LAFD) and pulse laser ablation in liquids (PLAL) were used for the growth of ZnO, SnO2 and yttria stabilized ZrO2 (YSZ) micro and nanocrystals with different morphologies, respectively. Regarding the YSZ host, trivalent lanthanide ions were optically activated by in-situ doping and co-doping. The influence of the defect energy states on the optical properties of the different undoped and doped metal oxide hosts is investigated under ultraviolet and infrared excitation by means of photoluminescence and photoluminescence excitation.","PeriodicalId":232941,"journal":{"name":"Microtechnologies for the New Millennium","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124577724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design of the charge push-through electronics for fully implantable artificial cochlea","authors":"Jaromír Zák, Z. Hadaš, D. Dušek, J. Pekárek, V. Svatos, L. Janak, J. Prásek","doi":"10.1117/12.2178987","DOIUrl":"https://doi.org/10.1117/12.2178987","url":null,"abstract":"The artificial cochlear implant is the only way how to get lost hearing back in some cases. Existing artificial cochlear devices use two separated parts for this purpose: a signal processing unit with transmitter and an implantable receiver with electrodes. This approach is applicable but not fully implantable. A new complex approach to design of a fully implantable artificial cochlea is described in this article. The proposed artificial cochlea consists of many subcircuits which have to be designed in close context to reach optimal performance and the lowest power consumption. Power consumption should be decreased to a value which allows using cochlear implant as a zero-powered system. A combination of micro-mechanized diaphragm filter bank, possible energy harvesting power source and especially ultra-low power processing electronics is presented in this article. A unique technique for nerve stimulatory output signal generation is discussed. This new technique named charge push-through electronics should use the major part of energy generated by energy harvesting subcircuit for output useful signal generation with minimal undesirable current. Mechanical parts of the subcircuits were simulated as complex electro-mechanical simulation models in ANSYS, CoventorWare, Matlab and SPICE environment. First, the real energy harvesting power source (human motion and temperature) behavior was measured. The model of this behavior was created in simulation environment and then the whole electronics simulation model for energy harvesting circuits was estimated. Next, signal processing circuits powered from energy harvesting power source were designed and simulated. The new signal processing circuits were simulated in relation to the results of complex electro mechanical diaphragm and SPICE energy harvesting power source simulation.","PeriodicalId":232941,"journal":{"name":"Microtechnologies for the New Millennium","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121726409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Calculation of accurate channel spacing of an AWG optical demultiplexer applying proportional method","authors":"D. Seyringer, E. Hodzic","doi":"10.1117/12.2178271","DOIUrl":"https://doi.org/10.1117/12.2178271","url":null,"abstract":"We present the proportional method to correct the channel spacing between the transmitted output channels of an AWG. The developed proportional method was applied to 64-channel, 50 GHz AWG and the achieved results confirm very good correlation between designed channel spacing (50 GHz) and the channel spacing calculated from simulated AWG transmission characteristics.","PeriodicalId":232941,"journal":{"name":"Microtechnologies for the New Millennium","volume":"130 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122053911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solderjet bumping technique used to manufacture a compact and robust green solid-state laser","authors":"P. Ribes, T. Burkhardt, M. Hornaff, S. Kousar, D. Burkhardt, E. Beckert, M. Gilaberte, D. Guilhot, D. Montes, M. Galán, S. Ferrando, M. Laudisio, T. Belenguer, S. Ibarmia, P. Gallego, J. A. Rodríguez, R. Eberhardt, A. Tünnermann","doi":"10.1117/12.2178373","DOIUrl":"https://doi.org/10.1117/12.2178373","url":null,"abstract":"Solder-joining using metallic solder alloys is an alternative to adhesive bonding. Laser-based soldering processes are especially well suited for the joining of optical components made of fragile and brittle materials such as glasses, ceramics and optical crystals due to a localized and minimized input of thermal energy. The Solderjet Bumping technique is used to assemble a miniaturized laser resonator in order to obtain higher robustness, wider thermal conductivity performance, higher vacuum and radiation compatibility, and better heat and long term stability compared with identical glued devices. The resulting assembled compact and robust green diode-pumped solid-state laser is part of the future Raman Laser Spectrometer designed for the Exomars European Space Agency (ESA) space mission 2018.","PeriodicalId":232941,"journal":{"name":"Microtechnologies for the New Millennium","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132032604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microfluidic generation and optical manipulation of ultra-low interfacial tension droplets","authors":"G. Bolognesi, Alex L. Payne-Dwyer, A. Ward, A. Kirby, M. Neil, C. Bain, O. Ces","doi":"10.1117/12.2178964","DOIUrl":"https://doi.org/10.1117/12.2178964","url":null,"abstract":"We present a microfluidic platform for the generation, characterization and optical manipulation of monodisperse oil droplets in water with equilibrium interfacial tensions on the order of 0.1-1μN/m. An oil-in-water emulsion containing the surfactant Aerosol OT, heptane, water and sodium chloride under conditions close to the microemulsion phase transition was used. Through active control of the emulsion salinity and temperature, our microfluidic platform offers the unique capability of tuning the interfacial tension of droplets in the range of 1μN/m to few mN/m according to the operation required. Upon collection in a separate observation chamber, droplets were characterized by using video microscopy-based measurement of thermally-induced capillary waves at the droplet interface. Holographic optical tweezers were used to manipulate the droplets and construct 3D nanofluidic networks consisting of several droplets connected by stable oil threads a few nanometers across.","PeriodicalId":232941,"journal":{"name":"Microtechnologies for the New Millennium","volume":"197 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131701974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SiN-assisted polarization-insensitive multicore fiber to silicon photonics interface","authors":"G. Poulopoulos, D. Kalavrouziotis, P. Mitchell, J. Macdonald, P. Bakopoulos, H. Avramopoulos","doi":"10.1117/12.2179077","DOIUrl":"https://doi.org/10.1117/12.2179077","url":null,"abstract":"We demonstrate a polarization-insensitive coupler interfacing multicore-fiber (MCF) to silicon waveguides. It comprises a 3D glass fanout transforming the circular MCF core-arrangement to linear and performing initial tapering, followed by a Spot-Size-Converter on the silicon chip. Glass waveguides are formed of multiple overlapped modification elements and appropriate offsetting thereof yields tapers with symmetric cross-section. The Spot-Size-Converter is an inverselytapered silicon waveguide with a tapered polymer overcladding where light is initially coupled, whereas phase-matching gradually shifts it towards the silicon core. Co-design of the glass fanout and Spot-Size-Converter obtains theoretical loss below 1dB for the overall Si-to-MCF transition in both polarizations.","PeriodicalId":232941,"journal":{"name":"Microtechnologies for the New Millennium","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122708618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic microfluidic system for isolation of single cells","authors":"Richard Mitterboeck, G. Kokkinis, T. Berris, F. Keplinger, I. Giouroudi","doi":"10.1117/12.2181194","DOIUrl":"https://doi.org/10.1117/12.2181194","url":null,"abstract":"This paper presents the design and realization of a compact, portable and cost effective microfluidic system for isolation and detection of rare circulating tumor cells (CTCs) in suspension. The innovative aspect of the proposed isolation method is that it utilizes superparamagnetic particles (SMPs) to label CTCs and then isolate those using microtraps with integrated current carrying microconductors. The magnetically labeled and trapped CTCs can then be detected by integrated magnetic microsensors e.g. giant magnetoresistive (GMR) or giant magnetoimpedance (GMI) sensors. The channel and trap dimensions are optimized to protect the cells from shear stress and achieve high trapping efficiency. These intact single CTCs can then be used for additional analysis, testing and patient specific drug screening. Being able to analyze the CTCs metastasis-driving capabilities on the single cell level is considered of great importance for developing patient specific therapies. Experiments showed that it is possible to capture single labeled cells in multiple microtraps and hold them there without permanent electric current and magnetic field.","PeriodicalId":232941,"journal":{"name":"Microtechnologies for the New Millennium","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124880730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A CMOS merged CDR and continuous-time adaptive equalizer","authors":"C. Sánchez-Azqueta, J. Aguirre, C. Gimeno, C. Aldea, S. Celma","doi":"10.1117/12.2178993","DOIUrl":"https://doi.org/10.1117/12.2178993","url":null,"abstract":"We present a low-voltage merged CDR and cntinuous-time adaptive equalizer capable to compensate the attenu- ation of a SI-POF channel while at the same time synchronizing and regenerating the incoming signal in a single stage. The system operates at 1.25 Gbps for NRZ modulation through a 50-m SI-POF channel and it is designed in standard 0.18-μm CMOS fed at 1 V with a power consumption of 43.4 mW.","PeriodicalId":232941,"journal":{"name":"Microtechnologies for the New Millennium","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122091315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A SU-8-based flexible microprobe for close and distal recordings from the cortical network","authors":"X. Illa, B. Rebollo, G. Gabriel, Maria V. Sanchez-Vives, R. Villa","doi":"10.1117/12.2180454","DOIUrl":"https://doi.org/10.1117/12.2180454","url":null,"abstract":"A 16-electrode flexible microprobe presenting an array of holes in its sensing area has been developed using SU-8 negative photoresist as a substrate material. The design of the microprobe consisted on six groups of 2-3 electrodes (50 μm in diameter and separated by 200 μm) placed in-between the array of holes. Distances between each group were appropriated for recording from a ferret slice, allowing us to evaluate the close versus the distant network activity. The holes were designed to allow the flow of oxygenated solution through the probe when measuring the neural activity of cortical slides maintained in vitro, while the gold electrodes have been modified with platinum black to decrease its impedance value and, therefore, improve the measurements. In particular, with this SU-8 microprobe it has been possible to register spontaneous slow oscillations and also induced activity in all 16 channels. The holes were useful to position puffers that allowed us to locally delivered drugs (glutamate) and to register its response. In addition, they were also used for sticking electrodes to simultaneously record single units that allowed us the synchronous recording of population activity (local field potential) with the electrodes of the probe and single unit activity (with glass or tungsten electrodes), demonstrating the feasibility of using SU-8 for the fabrication of neural microprobes as it can be customized to the required design.","PeriodicalId":232941,"journal":{"name":"Microtechnologies for the New Millennium","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116601564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Living photonics: monitoring light propagation through cells (LiPhos)","authors":"D. King, Elise Røge Hedegaard, T. Ackermann, C. Rius, X. Muñoz‐Berbel, Heidi Knudsen, Isaac Rodríguez-Rodríguez, B. Dorado, Erica Alvarez, J. Ducrée, V. Andrés, U. Simonsen, A. Llobera","doi":"10.1117/12.2181306","DOIUrl":"https://doi.org/10.1117/12.2181306","url":null,"abstract":"The LiPhos project (EU FP7 Grant Agreement No.: 317916, www.liphos.eu) aims to develop three different biophotonic diagnosis tools (BDTs), based on living photonics, namely: single layer living photonics (SLLP), single cell analysis (SCA); and multi-layer living photonics (MLLP). By Measuring of what we term the Photonic Fingerprint (or PIN), of the cells in such BDTs, should make it is possible to differentiate between healthy and non-healthy cell or tissue states. Moreover, the effect of specific drugs and pro-inflammatory agents could be assessed. This concept is currently being applied to the diagnosis of cardiovascular diseases (CVD).","PeriodicalId":232941,"journal":{"name":"Microtechnologies for the New Millennium","volume":"96 35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129310952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}