{"title":"Some of The Biochemical Effects of Artemether on the Reproductive Hormones in Pregnant Wistar Rats.","authors":"A. Tijani, Sa Biliamin, Ma Adekilekun","doi":"10.4314/TJHC.V18I1.64481","DOIUrl":"https://doi.org/10.4314/TJHC.V18I1.64481","url":null,"abstract":"Artemether and it derivatives have been shown in many studies to be effective in the treatment of both acute uncomplicated and severe malaria. They induce more rapid reduction of parasetaemia than other antimalarial drugs. This research work studied the effects of intramuscular Artemether on some of the hormones of reproduction in pregnant wistar rats. Twelve (12) pregnant rats were divided equally and randomly into one treatment and one control groups. The experimental animals in the treatment group were administered intramuscularly with 0.09ml of Artemether while those in the control group received phosphate buffered sal ine intramuscularly. Administration was done for seven days. Twenty four hour after the last administration, all the experimental animals were sacrificed using cervical dislocation. From the outcome of the study, it was observed that all the reproductive hormones analyzed were relatively lower in the animals in the treatment group treated with intramuscular Artemether compared with those in the control group. It was concluded that Artemether is embryo-toxic, causing abortion in the pregnant Wistar rats that received it.","PeriodicalId":23292,"journal":{"name":"Tropical Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2011-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88807156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rectal Signet-ring Cell Carcinoma associated with Schistosomiasis in A Nigerian Teenager: A Case Report and Literature Review","authors":"K. Adeniji, O. Ibrahim","doi":"10.4314/TJHC.V18I1.64489","DOIUrl":"https://doi.org/10.4314/TJHC.V18I1.64489","url":null,"abstract":"Rectal adenocarcinoma is rare in children and young adult worldwide. Apart from genetic predisposition, other factors including chronic schistosomal infection have been implicated in its aetiopathogenesis. Furthermore, many of the recorded cases of rectal carcinoma occurring along with schistosomiasis usually occur not commonly in teenagers but in older patients.We present an 18-year-old Nigerian male who came to the hospital on account of bloody diarrhoea and was later discovered to have signet-ring carcinoma of the rectum in association with schistosomiasis. Available literatures on role of schistosomiasis in aetiopathogenesis of colorectal adenocarcinoma are reviewed.","PeriodicalId":23292,"journal":{"name":"Tropical Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2011-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81771081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intestinal Parasitosis Among Unicef Primary School Pupils Of Isingwu Oraifite Ekwusigo Local Government Area, Southeastern Nigeria","authors":"Kv Okolo, N. Ozumba, V. Oguoma, E. Mbanefo","doi":"10.4314/TJHC.V18I1.64476","DOIUrl":"https://doi.org/10.4314/TJHC.V18I1.64476","url":null,"abstract":"","PeriodicalId":23292,"journal":{"name":"Tropical Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2011-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82629921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hypocalcaemia Occurring Within Forty-Eight Hours Of Birth In Term Infants With Severe Birth Asphyxia","authors":"A. N. Onyiriuka","doi":"10.4314/TJHC.V17I2.60979","DOIUrl":"https://doi.org/10.4314/TJHC.V17I2.60979","url":null,"abstract":"In this cross-sectional study, total serum calcium of 31 term infants with 1-minute Apgar score of 3 or less was measured and compared with those of their counterparts with 1-minute Apgar score of 7 and above. The total serum calcium of severely asphyxiated infants who had sodium bicarbonate administered during resuscitation was compared with those of their counterparts without sodium bicarbonate therapy. Infants with birth asphyxia were examined serially from time of birth and compared with their counterparts without birth asphyxia. Overall prevalence of early-onset neonatal hypocalcaemia (total serum calcium Keywords: Neonatal hypocalcaemia, birth asphyxia, bicarbonate therapy.","PeriodicalId":23292,"journal":{"name":"Tropical Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73508019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Spectrum of Benign Breast Diseases In Osogbo, Nigeria.","authors":"A. Oguntola, O. Akanbi, M. Adeoti, K. Ojemakinde","doi":"10.4314/TJHC.V17I2.67337","DOIUrl":"https://doi.org/10.4314/TJHC.V17I2.67337","url":null,"abstract":"","PeriodicalId":23292,"journal":{"name":"Tropical Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78258721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preliminary Investigations Of Effectiveness Of Herbal Remedies Used For HIV Infection In Nigeria","authors":"A. Onifade, A. Jewell, A. Okesina","doi":"10.4314/TJHC.V17I2.60998","DOIUrl":"https://doi.org/10.4314/TJHC.V17I2.60998","url":null,"abstract":"This study analysed some of the widely publicised herbal remedies in use for HIV infection in Nigeria, and investigated their efficacy scientifically. Those found to be efficacious will be subjected to further analysis to identify their active chemical components. The research deals directly with patients living with HIV/AIDS that are seeking treatment in herbal homes and hospitals. The herbal homes are regularly visited and newly diagnosed patients living with HIV/AIDS are recruited after confirmation of the disease. The herbal centres of priority are those located in Zaria (Kaduna state) and Osogbo (Osun state), Nigeria with all the nearby tertiary hospitals serving as diagnostic and treatment centres for HIV infection. Assessment of the effectiveness is based on laboratory and clinical parameters using World Health Organisation (WHO) and United State Centre for Disease Control and Prevention (CDC) criteria. Parameters will be assessed before commencing medication and periodic intervals up to two years when patients started medication of herbal remedies. There are variable significant laboratory and clinical findings depending on the type of herbal therapy used by the patient with about 20% of the herbal homes have potential effective herbal remedies for HIV infection, 60% with symptomatic treatment and 20% with potential toxic products. The patients taking Zam- z (Herbal home A treatment) improved clinically and with laboratory parameters within the three months of the normal treatment, however, study is still in progress to determine the withdrawal effects of the medication and role as complementary or alternative therapy to Highly Active Antiretroviral Therapy (HAART). Key Words : herbal medicine, HIV infection, Nigeria","PeriodicalId":23292,"journal":{"name":"Tropical Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84637644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors Influencing Antenatal Care Seeking Behaviour Among Women In Bangladesh","authors":"M. Rahman, S. Haque","doi":"10.4314/TJHC.V17I2.67338","DOIUrl":"https://doi.org/10.4314/TJHC.V17I2.67338","url":null,"abstract":"","PeriodicalId":23292,"journal":{"name":"Tropical Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89431107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychosocial Care And Adjustment Of Children And Families With Sickle Cell Disease: The Nigerian Perspective","authors":"M. Tunde-Ayinmode","doi":"10.4314/TJHC.V17I2.60973","DOIUrl":"https://doi.org/10.4314/TJHC.V17I2.60973","url":null,"abstract":"Nigeria is a country with one of the largest number of sickle cell disease (SCD) patients in the world. Many affected children and their families experience many adverse psychosocial effects. Most SCD clinics and other outlets of SCD care in Nigeria focus mainly on the physical well being of affected children with little or no concern about prevention or management of these associated psychosocial complications. This has negative implication for management and manageability of the disease. This paper is aimed at reviewing psychosocial care and adjustment in sickle cell disease with focus on the present status, problems and possibilities in Nigeria. This is a review article on psychosocial care of SCD children and their families, using manual search for literature in library, internet and textbooks. The psychosocial component of the care of SCD patients in Nigeria is still deficient and need to be improved. Major problems of psychosocial care of SCD patients in Nigeria include: insufficient attention to data gathering on problems and coping strategies, inadequate health education and public enlightenment on coping strategies and shortage of trained human resources, social welfare services and infrastructure. Sustained commitment to tackling these problems will upgrade psychosocial care for SCD children and their families in Nigeria. This is achievable if the knowledge and skill of psychosocial care is made available to all groups of health professionals involved in health care delivery to children; with the mental health professionals spearheading the initiative. Key words : Sickle cell disease, children and family, psychosocial care, adjustment.","PeriodicalId":23292,"journal":{"name":"Tropical Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81560456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reasons For Cancellation of Elective Paediatric Surgery Cases","authors":"I. Abdur-Rahman, I. Kolawole","doi":"10.4314/TJHC.V17I2.60976","DOIUrl":"https://doi.org/10.4314/TJHC.V17I2.60976","url":null,"abstract":"Many factors have contributed to incessant cancellation of elective cases in paediatric surgery. The objective of this study was to review the reasons for cancellation of such cases in our centre and to suggest solutions to these problems. Prospective collation of information on all cancelled elective paediatric surgical cases was done. The bio-data on; clinical diagnosis and reasons for cancellation were documented. The study period was 18 months (March 2006- August 2007). Causes of cancellation were grouped into patients' factors (group A), parental factors (group B), and institutional factors (group C) There were 437 elective paediatric surgery cases within this period of which 298 (68.2%) were day cases and 139 (31.8%) were in-patients. Sixty-one patients (14%) were cancelled [36 (8.2%) day cases and 25 (5.8%) in-patients] of which 49 (80.3%) were males, 10 (16.4%) were females and 2 (3.3%) cases of ambiguous genitalia. The age ranged between 30 days and 11 years with a mean of 33.4 months ± SD of 34.4 months. The commonest reason for cancellation were in group A (22, 36.1%), followed by groups B and C (17or 27.9% each). The commonest reason in group A was Upper respiratory tract infection (59.1%), for group B was parents' refusal to present wards on the day of surgery (88.2%) and for group C was impromptu public holidays (58.8%). Elective paediatric surgery cases are usually cancelled in our centre due to Upper Respiratory Tract Infection (URTI) in children and parents' refusal to present their wards on surgery day. There is a need to properly review children with runny nostrils before cancellation because some children's nostrils are chronically wet and it may be delicate to postpone their operation. Adequate counseling of parents will reduce default. Keywords: cancellation, elective, day-case, paediatric surgery","PeriodicalId":23292,"journal":{"name":"Tropical Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76243417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. J. Abulraheem, J. P. Fabiy, S. K. Babatunde, M. A. Alayande, A. Akanbi, A. Fawole
{"title":"Prevalence Of Malaria Parasitaemia In Pregnant Women Attending Antenatal Clinics At The University Of Ilorin Teaching Hospital, Ilorin, Nigeria","authors":"O. J. Abulraheem, J. P. Fabiy, S. K. Babatunde, M. A. Alayande, A. Akanbi, A. Fawole","doi":"10.4314/TJHC.V17I2.61035","DOIUrl":"https://doi.org/10.4314/TJHC.V17I2.61035","url":null,"abstract":"The paper studied the prevalence of malaria parasitaemia among pregnant women attending antenatal clinics at University of Ilorin Teaching Hospital, Ilorin, Kwara State. A total of 350 blood samples were collected from consecutive pregnant women registering at the antenatal clinics. It was examined for malaria parasites, using both thick and thin films. Cellulose acetate electrophoresis was used to detect the haemoglobin genotype; haematocrit method was used to determine the packed cell volume (PVC) and tube technique to determine the blood group and rhesus typing of the subjects. An overall prevalence rate of 10.5% was obtained. Prevalence rate for age group 14-20 was 14% while age group 41- 50 had no infection. Primigravidae had higher infection rate (14%) than Multigravidae (8%) and the difference was significant (P Key words: Parasitaemia, Plasmodium falciparum, Socioeconomic status","PeriodicalId":23292,"journal":{"name":"Tropical Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90046565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}