Trauma monthly最新文献

筛选
英文 中文
Magnetic Resonance Imaging in Traumatic Brachial Plexopathy: A Guiding Light for Surgeons 创伤性臂丛病的磁共振成像:外科医生的指路明灯
IF 0.5
Trauma monthly Pub Date : 2021-04-01 DOI: 10.30491/TM.2021.270888.1232
Aaqib Manzoor, N. Choh, Omair Shah, T. Gojwari, T. Shera, M. Bhat, Shadab Maqsood, A. Bashir
{"title":"Magnetic Resonance Imaging in Traumatic Brachial Plexopathy: A Guiding Light for Surgeons","authors":"Aaqib Manzoor, N. Choh, Omair Shah, T. Gojwari, T. Shera, M. Bhat, Shadab Maqsood, A. Bashir","doi":"10.30491/TM.2021.270888.1232","DOIUrl":"https://doi.org/10.30491/TM.2021.270888.1232","url":null,"abstract":"Background: The brachial plexus is a group of major neural structures providing sensory and motor innervations to the upper limb. The brachial plexus originates from four cervical (C5-C8) and the first thoracic root (T1). Objectives: The aim of the current study was to evaluate the role of MRI in the diagnosis and localization of traumatic brachial plexopathies and co-relate MRI findings with intraoperative findings wherever possible. Methods: A total of 40 patients with traumatic brachial plexitis underwent a dedicated MRI at our institution. Clinical and electrodiagnostic tests were done in all patients. The findings of MR imaging were correlated with surgical findings as concordant (CR), partially concordant (PC), or nonconcordant (NC). Patients who were not operated were followed over a period of six months to one year. Results: Road traffic accidents (n=32) were the most common cause of brachial plexopathy in our study. Clinical evaluation revealed sensory symptoms in 28 (70 %), motor symptoms in 25 (63%), and autonomic manifestation in 2 (5%) patients. The electrodiagnostic tests were abnormal in 30 (75%) of our patients. MRI findings included pre-ganglionic injury (n=5, 12.5%), post-ganglionic injury (n=17 42.5%), mixed injury (n=9 22.5%) and normal in 9 (22.5%) patients. MRI findings were perfectly concordant with surgical findings in 23(66%), partially concordant in 8(23%), and nonconcordant in 4(11%) patients. MRI has a sensitivity of 87.88%, specificity of 100%, and accuracy of 89.47% for traumatic brachial plexopathy evaluation. Conclusion: MRI is an essential component of traumatic brachial plexopathy evaluation. MR imaging, although not absolutely perfect, helps in the localization of injury in traumatic plexopathies (pre vs. post-ganglionic), thereby acting as a guiding light for surgical management. Normal MRI in traumatic brachial plexopathy is an enigma, and management in these patients should be based on clinical and electrodiagnostic tests.","PeriodicalId":23249,"journal":{"name":"Trauma monthly","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76146059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Dexmedetomidine on Blood Pressure in Hypertension Patients after Emergency Laparotomy for Trauma: A Randomized Double-blind Clinical Trial 右美托咪定对创伤急诊剖腹手术高血压患者血压的影响:一项随机双盲临床试验
IF 0.5
Trauma monthly Pub Date : 2021-04-01 DOI: 10.30491/TM.2021.274843.1249
R. M. Gargari, H. Anvari
{"title":"Effect of Dexmedetomidine on Blood Pressure in Hypertension Patients after Emergency Laparotomy for Trauma: A Randomized Double-blind Clinical Trial","authors":"R. M. Gargari, H. Anvari","doi":"10.30491/TM.2021.274843.1249","DOIUrl":"https://doi.org/10.30491/TM.2021.274843.1249","url":null,"abstract":"Background: Patients with a history of hypertension experience higher postoperative complications than healthy individuals. The frequency of such complications is also higher in emergency patients than elective ones; therefore, it seems that preventive measures are essential. Objectives: The present study aimed at determining the effect of dexmedetomidine on blood pressure in patients with hypertension after emergency laparotomy for trauma. Methods: The present study was a randomized, double-blind clinical trial performed from 2019 to 2020 on patients with a history of hypertension undergoing emergency laparotomy. Patients received the intervention 15 minutes before surgery (the intervention group: intravenous (iv) dexmedetomidine and the control group: normal saline), and the intensity of the pain(VAS), agitation(RASS), and blood pressure were measured and compared at different time points. Data were compared using SPSS software (version 21) by t-test and Chi-square tests considering a significance level of <0.05. Results: There were statistically significant differences between the two groups just after the drug infusion and at all studied time points (p <0.05), so that the intervention group had more stable blood pressure. Pain intensity (p <0.05) and the degree of agitation (p <0.05) in the intervention group were significantly lower than that in the control group at all studied time points. Conclusion: Dexmedetomidine infusion leads to a stabilization of blood pressure during surgery and after surgery, pain relief, and agitation in patients with hypertension undergoing emergency laparotomy for trauma.","PeriodicalId":23249,"journal":{"name":"Trauma monthly","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87639006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pattern of Injury and Outcome of Victims in Ahvaz Terrorist Attack 阿瓦士恐怖袭击中受害者的伤害模式和结果
IF 0.5
Trauma monthly Pub Date : 2021-04-01 DOI: 10.30491/TM.2021.227086.1098
H. Araghizadeh, H. Khoshmohabat, S. H. Hossini, M. Moayed
{"title":"Pattern of Injury and Outcome of Victims in Ahvaz Terrorist Attack","authors":"H. Araghizadeh, H. Khoshmohabat, S. H. Hossini, M. Moayed","doi":"10.30491/TM.2021.227086.1098","DOIUrl":"https://doi.org/10.30491/TM.2021.227086.1098","url":null,"abstract":"Background: Responses for medical emergencies can be different during most terrorist attacks in which civilians and military personnel might be killed or wounded. Objectives: The present study aimed to reflect on injury patterns and the outcome of victims in terrorist attacks. Methods: A retrospective research design study was conducted on the data obtained from terrorist attacks in the city of Ahvaz, Iran, on September 22, 2018. In this deadly incident, 92 military and civilian victims had been transferred to hospitals within the first 24 hours. To this end, the data including age, gender, causes, site of injuries, outcomes, and the Injury Severity Score (ISS) values were analyzed.  Data were acquired from the Iranian Legal Medicine Organization, the Iranian Emergency Department, as well as health care facilities. Results: The findings revealed that, out of 92 victims of Ahvaz terrorist attack, 85 cases (92.4%) were men. The mean age of these individuals was about 28.68±11.22 years and 41.3% of them were in need of urgent surgical interventions. There was no information regarding casualties in 22.3% of the cases. Moreover, 25% of the causalities had led to death. The mean of ISS was 8.19±13. Besides, there was a significant relationship between ISS values and patient outcomes (p <0.0001). A relationship was also observed between multiple injuries and mortality rates although it did not include main body parts. Conclusion: The results showed that the mortality rate of casualties in the Ahvaz terrorist attack was high. With respect to the findings, extensive actions are needed to maintain the readiness of the emergency medical care services and to manage such events.","PeriodicalId":23249,"journal":{"name":"Trauma monthly","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90077216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Evaluation of Various Methods of Drainage of the Abdominal Cavity in Patients with Secondary Bacterial Peritonitis 继发性细菌性腹膜炎不同腹腔引流方法的比较评价
IF 0.5
Trauma monthly Pub Date : 2021-04-01 DOI: 10.30491/TM.2021.281240.1278
M. I. Bokarev, A. I. Mamykin, Khaled J Alali, Andrey I Demyanov, E. Stolyarchuk, A. E. Markarov
{"title":"Comparative Evaluation of Various Methods of Drainage of the Abdominal Cavity in Patients with Secondary Bacterial Peritonitis","authors":"M. I. Bokarev, A. I. Mamykin, Khaled J Alali, Andrey I Demyanov, E. Stolyarchuk, A. E. Markarov","doi":"10.30491/TM.2021.281240.1278","DOIUrl":"https://doi.org/10.30491/TM.2021.281240.1278","url":null,"abstract":"Background: Secondary peritonitis is a serious complication of all the inflammatory diseases and injuries of the abdominal organs and requires urgent surgical intervention. The mortality rate of patients with secondary bacterial peritonitis (SBP) reaches 70%. In some patients, despite the treatment, secondary peritonitis turns into tertiary peritonitis (TP), which complicates the healing process and aggravates the prognosis. Inadequate drainage of the abdominal cavity is a possible contributing factor to the formation of TP. Aims: A prospective study of the result of surgical treatment of patients with SBP was carried out to improve the results of treatment. Methods. The study included 608 patients with SBP who underwent surgery in a clinical hospital in Russia in 2013-2019. All the patients were divided into groups depending on the method of draining the abdominal cavity and on signs of the purulent process generalization, the marker of which was multiple organ failure. Efficiency of abdominal drainage (by the incidence of TP) and of treatment results (in terms of mortality) were assessed in each group. Results: In patients without signs of the purulent process generalization, drainage of the abdominal cavity with drainage tubes (293 observations) is accompanied by the development of TP in 4.1% of cases and by mortality in 22.9%. If the purulent process is of a generalized nature (315 observations), the incidence of TP increases ten-fold and is 41.9%, and the mortality rate increases 2.7 times and reaches 62.8%. With the generalization of the purulent process, the efficiency of drainage of the abdominal cavity has a significant impact on the results of surgical treatment of patients with SBP. If abdominal drainage is carried out with drainage tubes (129 observations), the incidence of TP is 41.9%, and the mortality rate is 62.8%. Drainage of the abdominal cavity using traditional laparostomy (Bogota bag, 104 cases) is accompanied by the development of TP in 36.5% of cases and mortality in 45.2%. If the abdomen is drained using active laparostomy (VAC-system, 82 observations), the incidence of TP is reduced to 18.3% and mortality to 19.5%. Conclusion. Drainage of the abdominal cavity is the most important stage of surgical intervention in patients with SBP. In cases of the purulent process generalization, drainage of the abdominal cavity in the most effective way– by active laparostomy (VAC-system) will improve the results of treatment of these patients.","PeriodicalId":23249,"journal":{"name":"Trauma monthly","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90958437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Outcomes of Perilunate Dislocations and Perilunate Fracture-dislocations: A Review of 20 Cases 20例月骨周围脱位和月骨周围骨折脱位的手术疗效分析
IF 0.5
Trauma monthly Pub Date : 2021-04-01 DOI: 10.30491/TM.2021.237623.1140
Mehran Razavipour, S. Ghaffari, Alireza Kazemi, M. Azar
{"title":"Surgical Outcomes of Perilunate Dislocations and Perilunate Fracture-dislocations: A Review of 20 Cases","authors":"Mehran Razavipour, S. Ghaffari, Alireza Kazemi, M. Azar","doi":"10.30491/TM.2021.237623.1140","DOIUrl":"https://doi.org/10.30491/TM.2021.237623.1140","url":null,"abstract":"Background: Perilunate dislocations and perilunate fracture-dislocations (PLD/PLFD) are the second most common wrist injuries. Objectives: Given the limited available case series due to the rarity of these injuries, in this study, we report the functional outcomes of 20 patients who received surgical treatment with a mean follow-up of 28 months (range 24-36). Methods: We retrospectively reviewed the admissions to Imam Khomeini Hospital Sari, Iran, and included patients with (PLD/PLFD) who underwent surgical treatment between January 2014 to December 2019. We included 20 patients (16 males, mean age±SD=33.6±12.4) who had received urgent surgical treatment following the initial closed reduction in the emergency department. All of the patients received surgical treatment from the same surgical team using the dorsal approach. Results: We observed the average Mayo Wrist Score (MWS) of 73.8±8.4 (range 65-100) with excellent or good outcomes in 40% of patients. The MWS was slightly higher in patients with the non-dominant injured side, yet it did not significantly differ with those with a dominant hand injury (75.4±9.6 vs. 71.2±5.8, P=0.29). Furthermore, we did not find a significant difference in MWS between the lesser and greater arc injuries (76.5±10.1 vs. 71.1±5.7, P=0.15). The observed flexion and extension ROM were significantly lower than the contralateral side (p <0.001). Similar patterns of lower grip and pinch strength were observed on the injured side, which was significantly lower than the contralateral hand; 38.4±8.6 (74±14% of the contralateral) and 9.9±2.4 (81±15% of the contralateral), respectively (p <0.001). Conclusion: In line with other cohorts, the present case series demonstrates relatively good functional postoperative outcomes in PLD/PLFD. Our findings are comparable with prior reports concerning reasonably satisfactory MWS, ROM relative to the contralateral side and reported occasional mild pain with activity. Future studies should be directed to investigate long-term complications associated with these injuries, particularly the development of wrist osteoarthritis.","PeriodicalId":23249,"journal":{"name":"Trauma monthly","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74933139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Designing a Guideline for Emergency Medical Communication Center Staff to Help Road Traffic Crash Patients: A Delphi Study 设计急救医疗沟通中心人员协助道路交通事故患者的指引:德尔菲研究
IF 0.5
Trauma monthly Pub Date : 2021-01-01 DOI: 10.30491/TM.2021.250496.1177
Hojjat Shafaee, A. Ostadtaghizadeh, Davoud Khorasani-Zavareh, S. Nematollahi, J. Hirshon, A. Mirhaghi, M. Moradian
{"title":"Designing a Guideline for Emergency Medical Communication Center Staff to Help Road Traffic Crash Patients: A Delphi Study","authors":"Hojjat Shafaee, A. Ostadtaghizadeh, Davoud Khorasani-Zavareh, S. Nematollahi, J. Hirshon, A. Mirhaghi, M. Moradian","doi":"10.30491/TM.2021.250496.1177","DOIUrl":"https://doi.org/10.30491/TM.2021.250496.1177","url":null,"abstract":"Background: Injuries and deaths from RTC are critical health problems of societies and one of the main causes of death especially among the young. Objective: This study aimed to design and compile a guideline for emergency medical communication centers (EMCC) staff to provide direct assistance offered by road traffic crash (RTC) bystanders. Methods: Based on prior literature, the RTC bystanders' initial draft guideline contained 20 domains and 28 items. As a validation step, the draft guideline was reviewed by content experts (one emergency medicine and two disaster specialists) and modified based on their recommendations. The subsequent draft guideline was then reviewed in three Delphi rounds by 67 participants, including health professionals in emergencies and disasters, emergency medicine, nurses, emergency medical experts, and EMCC staff. The accepted agreement coefficient was set at ≥70%. As the final step, an expert consensus meeting was held to review the guideline. Results: The participants agreed on 56 items regarding 20 domains, including scene safety, hand precautions, and personal protection, alertness assessment, respiration, cardiopulmonary resuscitation (CPR), bleeding control, recovery position, splinting, rapid evacuation, scene management, patient transfer, triage, spinal cord injury prevention and immobilization, injured transportation, psychological support, hypothermia prevention, water and food, amputated limb protection, and support of deceased people. Two items in relation to airway opening maneuvers were added to the guideline during the expert consensus meeting. Conclusion: Compared to other RTC bystander guidelines for EMCC staff, more comprehensive guidelines can be served as a basis for directing RTC bystanders to provide assistance. Important areas of hand care and personal protection, breathing, airway, splinting, scene management, mental and psychological support, and support of deceased people were included in this guideline. EMCC staff can provide guidance to be performed by RTC bystanders. RTC bystanders can play important roles at crash scenes, including preventing secondary injury, supporting scene management, and providing first aid for the injured people. This guideline can be used to help direct appropriate care and behavior by RTC bystanders.","PeriodicalId":23249,"journal":{"name":"Trauma monthly","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82422715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying Challenges of Providing Care for Trauma Patients; A Concurrent Mixed Methods Study 识别创伤患者护理的挑战并行混合方法研究
IF 0.5
Trauma monthly Pub Date : 2021-01-01 DOI: 10.30491/TM.2021.223980.1082
Zahra Jamshidi, K. Tabrizi, M. Fallahi-khoshknab, A. Dalvandi, F. Vizeshfar, H. Khankeh
{"title":"Identifying Challenges of Providing Care for Trauma Patients; A Concurrent Mixed Methods Study","authors":"Zahra Jamshidi, K. Tabrizi, M. Fallahi-khoshknab, A. Dalvandi, F. Vizeshfar, H. Khankeh","doi":"10.30491/TM.2021.223980.1082","DOIUrl":"https://doi.org/10.30491/TM.2021.223980.1082","url":null,"abstract":"Background: Caregiving for trauma patients has many challenges. Inadequate knowledge of these challenges can affect the patients and worsen their conditions. Objectives: We aimed to explore the caregivers’ experiences about these challenges and problems of caring for patients with trauma emergencies. Methods: The study adopted a concurrent triangulation mixed-method and was conducted in Shahid Rajaee Hospital, southern Iran, in 2019. Semi-structured interviews, focus groups, observation and ward document assessments were conducted with focusing on the challenges experienced by the caregivers. A checklist was used to assess the performance of caregivers and measure the indices related to the care process. Statistical results and qualitative data on the main categories were compared and integrated for data analysis. Results: In total,307 codes were extracted by analyzing the content of the interviews and available evidence. The codes were summarized in 20 subcategories, and six main categories were extracted as follows: lack of professional capability, uncoordinated team response, deficits in managerial commitments, inadequate work motivation, complex nature of trauma emergency, and lack of clinical communication. The quantitative results indicated that caregivers’ performance was considerably far from the expected scores and also many indices indicated a waste of time in responding to the patient needs. Conclusion: Various dimensions of trauma care challenges indicate that professional capability, team coordination and communication, managerial commitments and work motivation considering the complex nature of trauma emergency wards are crucial to enhance patients' access to optimum quality care. Caregivers’ performance and quality of indices also affect the care process. Future studies are required for compiling strategies and protocols for the quality of care for trauma patients.","PeriodicalId":23249,"journal":{"name":"Trauma monthly","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76985228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prophylactic Use of Tranexamic Acid on Blood Loss in Cesarean Delivery: A Randomized Controlled- Clinical Trial 氨甲环酸预防剖宫产出血:一项随机对照临床试验
IF 0.5
Trauma monthly Pub Date : 2021-01-01 DOI: 10.30491/TM.2021.219676.1073
E. Jafarbegloo, Faride Faridnya, R. Ahangari, A. Mohammadbeigi
{"title":"Prophylactic Use of Tranexamic Acid on Blood Loss in Cesarean Delivery: A Randomized Controlled- Clinical Trial","authors":"E. Jafarbegloo, Faride Faridnya, R. Ahangari, A. Mohammadbeigi","doi":"10.30491/TM.2021.219676.1073","DOIUrl":"https://doi.org/10.30491/TM.2021.219676.1073","url":null,"abstract":"Background: Post-partum haemorrhage (PPH) is a major cause of maternal mortality worldwide. Tranexamic acid, an anti-fibrinolytic agent, is a novel approach in an attempt to prevent this dreadful complication. Objective: This study aimed to evaluate the efficacy and safety of tranexamic acid in reducing blood loss during and after cesarean section (CS). Methods: In this prospective randomized placebo-controlled clinical trial, 50 pregnant women were randomized into two groups. In the study group, 25 women received tranexamic acid 10 minutes before CS, whereas in the control group 25 women received distilled water. Blood was collected during two periods. The first time was from placental delivery to the end of CS and the second was from the end of CS to 2 h postpartum. The volume of blood was measured and compared between the two groups. Results: Tranexamic acid significantly reduced the quantity of blood from the end of CS to 2 h postpartum, which was 65.15±31.97 mL and 101.14±44.94 mL in the study and control groups, respectively (P =0.002). It also significantly reduced the volume of total blood from placental delivery to 2 h postpartum, which was 616.32±176.87 mL and 731.45±178.79 mL in the study and control groups (P =0.028). Total blood loss in the study group was 18.7% less than the control group. No complications or side effects were reported in the groups. Conclusions: Tranexamic acid statistically reduces the volume of blood loss from placental delivery to 2 h postpartum and its use was not associated with any side effects or complications. Therefore, tranexamic acid can be used as a safe and effective approach to reducing bleeding resulting from CS.","PeriodicalId":23249,"journal":{"name":"Trauma monthly","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89879117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Dense Bone-Derived 3d Bioscaffold: Preparation, Characterization, and Assessment of Its Potential for Bone Marrow Mesenchymal Stem Cells (BMSCS) Growth and Differentiation 致密骨来源的三维生物支架:制备、表征和评估其对骨髓间充质干细胞(BMSCS)生长和分化的潜力
IF 0.5
Trauma monthly Pub Date : 2021-01-01 DOI: 10.30491/TM.2021.214604.1049
Rozita Ghahremani, A. Asadi, S. Zahri
{"title":"Dense Bone-Derived 3d Bioscaffold: Preparation, Characterization, and Assessment of Its Potential for Bone Marrow Mesenchymal Stem Cells (BMSCS) Growth and Differentiation","authors":"Rozita Ghahremani, A. Asadi, S. Zahri","doi":"10.30491/TM.2021.214604.1049","DOIUrl":"https://doi.org/10.30491/TM.2021.214604.1049","url":null,"abstract":"Background: Since bone defects can result in different disabilities, many efforts have been made to bone tissue engineering. In this case, scaffolds play an important role as a key element of tissue engineering in providing three-dimensional structure for cell growth in vitro Objective: The aim of the present study was to provide the three-dimensional biological bioscaffold from the bovine femur dense bone and investigate the possibility of its potential for application in tissue engineering as biological 3D ECM bioscaffold via mesenchymal stem cells seeding and differentiation toward bone tissue. Methods: For the preparation of bioscaffolds, after cutting bovine femur bone into small pieces, demineralization and decellularization were done. Bioscaffolds biocompatibility was evaluated using an MTT assay. The morphological and cell adhesion characteristics of Bone marrow mesenchymal stem cells (BMSCs) on the bioscaffolds were evaluated using Scanning Electron Microscopy (SEM) technique. Finally, the cells were treated with an osteogenic differentiation medium and then evaluated for differentiation. Results: Histological studies showed that the use of sodium dodecyl sulfate (2.5%) for 8 h eliminated the cells. Radiography and calcium oxalate test confirmed demineralization. MTT assay and SEM studies showed that the obtained bioscaffolds are biocompatible and could provide an optimum three-dimensional environment for cell adhesion and movement. Moreover, the Alizarin red staining showed a higher differentiation rate for BMSCs. Conclusion: In the present study, bone-derived 3D bioscaffold showed an important role in the growth and differentiation of BMSCs, due to the natural characteristics, cell adhesion properties, and potential to enhance differentiation toward bone tissue. It may have the potential for use as bioscaffold as supporting metrics for maintenance, growth in bone tissue engineering.","PeriodicalId":23249,"journal":{"name":"Trauma monthly","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74809172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of an Injury Prevention Program on Traumatic Factors and Athletic Performance in Judo Athletes: MSSLSTS Intervention 伤害预防项目对柔道运动员创伤因素和运动成绩的影响:MSSLSTS干预
IF 0.5
Trauma monthly Pub Date : 2021-01-01 DOI: 10.30491/TM.2021.214296.1045
M. Mahmoudkhani, A. Shakibaee, H. Minoonejad, R. Rajabi, A. Barati
{"title":"Effect of an Injury Prevention Program on Traumatic Factors and Athletic Performance in Judo Athletes: MSSLSTS Intervention","authors":"M. Mahmoudkhani, A. Shakibaee, H. Minoonejad, R. Rajabi, A. Barati","doi":"10.30491/TM.2021.214296.1045","DOIUrl":"https://doi.org/10.30491/TM.2021.214296.1045","url":null,"abstract":"Background: Judo as martial arts have a higher risk of trauma during training rather than competition. Thus, an efficient training procedure should be accomplished. Objectives: Since the use of trauma prohibition approaches and athletic performance enhancement is essential, this study aimed at investigating the effect of 8-week Judo Specific Functional Training (JSFT) on the Traumatic factors and athletic performance in male judokas. Methods: 46 subjects were randomly classified into 2 groups of experimental (N: 23) and control (N: 23) groups. For eight weeks, the experimental group attended a JSFT program designed by the researchers. The control group participated in the usual judo training program presented by the coaches. The exercises were accomplished 3 times per week for 90 minutes each session. The subjects participated in pre-and post-tests. In order to approve the data normality and compare the variables, Shapiro-Wilk, ANCOVA analysis was implemented at the significant level of p˂ 0.05 using SPSS (version 21). Results: The outcomes showed that the scores of functional movement screening (p=0.001), upper extremity Y balance test (p=0.001), vertical jump (p=0.001) and JSFT (p=0.001) significantly increased among the experimental group in comparison to the control group. Conclusions: The JSFT program simultaneously modifies or decreases the Traumatic factors and improves athletic performance and offers more efficiency and effectiveness rather than the usual judo training programs.","PeriodicalId":23249,"journal":{"name":"Trauma monthly","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87043991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信