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Transactions of the American Clinical and Climatological Association最新文献

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THE BERT AND PEGGY DUPONT LECTURE: THE NEUROBIOLOGY AND EVOLUTION OF VOCAL LEARNING AND SPOKEN LANGUAGE. 伯特和佩吉-杜邦讲座：发声学习和口语的神经生物学和进化。
Transactions of the American Clinical and Climatological Association Pub Date : 2024-01-01
Erich Jarvis
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引用次数: 0
SURFACTANT PROTEIN A: AN INNATE IMMUNE MODULATOR AND THERAPEUTIC IN ASTHMA. 表面活性蛋白 a：一种先天免疫调节剂和哮喘治疗剂。
Transactions of the American Clinical and Climatological Association Pub Date : 2024-01-01
Monica Kraft, Julie Ledford
{"title":"SURFACTANT PROTEIN A: AN INNATE IMMUNE MODULATOR AND THERAPEUTIC IN ASTHMA.","authors":"Monica Kraft, Julie Ledford","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Surfactant Protein A (SP-A) is an innate immune modulator produced by the lung with known protective effects against bacteria and viruses. Its role in asthma, an inflammatory lung disease that affects 10% of the world's population, is not entirely known. In this review, we demonstrate that SP-A confers protection against exposure to interleukin-13, a type 2 cytokine integral to eosinophilic asthma, in a mouse model of SP-A deficiency, a house dust mite model of asthma, and in human bronchial epithelial cells from participants with asthma. We also show that small peptides derived from SP-A, such as the major allele of single nucleotide polymorphism (SNP) rs1965708, which includes the carbohydrate recognition domain of SP-A2 at position 223, reduce airway hyperresponsiveness, airway eosinophils, and mucus in a mouse model of asthma. These data suggest that SP-A has beneficial effects relevant to asthma and that an SP-A peptide may have a new therapeutic use in asthma.</p>","PeriodicalId":23186,"journal":{"name":"Transactions of the American Clinical and Climatological Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11316857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Former Officers 1884 Through 2023. 从 1884 年到 2023 年的前任官员。
Transactions of the American Clinical and Climatological Association Pub Date : 2024-01-01
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引用次数: 0
Recorder's Report. 记录员报告。
Transactions of the American Clinical and Climatological Association Pub Date : 2024-01-01
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引用次数: 0
ACCA Presidents, Past and Present (and Spouses). ACCA 前任和现任主席（及配偶）。
Transactions of the American Clinical and Climatological Association Pub Date : 2024-01-01
{"title":"ACCA Presidents, Past and Present (and Spouses).","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23186,"journal":{"name":"Transactions of the American Clinical and Climatological Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11316893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FINANCIAL COMPILATION. 财务汇编。
Transactions of the American Clinical and Climatological Association Pub Date : 2024-01-01
{"title":"FINANCIAL COMPILATION.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23186,"journal":{"name":"Transactions of the American Clinical and Climatological Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11316890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE BERT AND PEGGY DUPONT LECTURE. 伯特和佩吉-杜邦讲座。
Transactions of the American Clinical and Climatological Association Pub Date : 2024-01-01
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引用次数: 0
Present Members. 出席成员
Transactions of the American Clinical and Climatological Association Pub Date : 2024-01-01
{"title":"Present Members.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23186,"journal":{"name":"Transactions of the American Clinical and Climatological Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11316865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE ROLE OF HEALTH POLICY IN IMPROVING HEALTH OUTCOMES AND HEALTH EQUITY. 卫生政策在改善卫生成果和卫生公平方面的作用。
Transactions of the American Clinical and Climatological Association Pub Date : 2024-01-01
Karen E Joynt Maddox
{"title":"THE ROLE OF HEALTH POLICY IN IMPROVING HEALTH OUTCOMES AND HEALTH EQUITY.","authors":"Karen E Joynt Maddox","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Despite higher per-capita health care spending than any other country, the United States lags far behind in health outcomes. Additionally, there are significant health inequities by race, ethnicity, socioeconomic position, and rurality. One set of potential solutions to improve these outcomes and reduce inequities is through health policy. Policy focused on improving access to care through insurance coverage, such as the Affordable Care Act's Medicaid expansion, has led to better health and reduced mortality. Policy aimed at improving health care delivery, including value-based payment and alternative payment models, has improved quality of care but has had little impact on population health outcomes. Policies that influence broader issues of economic opportunity likely have a strong influence on health, but lack the evidence base of more targeted interventions. To advance health outcomes and equity, further policy change is crucial.</p>","PeriodicalId":23186,"journal":{"name":"Transactions of the American Clinical and Climatological Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11316889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE MARY ALLEN ENGLE AWARD. 玛丽·艾伦·恩格尔奖。
Transactions of the American Clinical and Climatological Association Pub Date : 2023-01-01
{"title":"THE MARY ALLEN ENGLE AWARD.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23186,"journal":{"name":"Transactions of the American Clinical and Climatological Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493748/pdf/tacca1330000157.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41213914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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