{"title":"Feature detection and classification of Action Potentials from detrusor smooth muscle cells","authors":"M. Padmakumar, K. Brain, R. Manchanda","doi":"10.1109/ICSMB.2016.7915109","DOIUrl":"https://doi.org/10.1109/ICSMB.2016.7915109","url":null,"abstract":"Unlike other excitable cells, the urinary bladder smooth muscle cells exhibit a wide variety of spontaneous Action Potential (sAP) shapes. The complex network of gap-junction coupled smooth muscle cells and innervations makes it difficult to comprehend the origin of such a shape diversity. It is expected that the shape of the sAPs observed intracellularly from a smooth muscle cell give hints about the syncytial properties of the tissue in its neighborhood. In this work, four major features - foot convexity, after hyperpolarization, after depolarization, and extended after hyperpolarization - which define the shape of sAPs were identified. Algorithms were designed to automatically detect the presence of each features. The proposed algorithms were able to detect the features with accuracies greater than 70%. Further, a scheme to label the sAPs based on the presence/absence of the features is also proposed. The labels could be used to classify the sAPs into different groups.","PeriodicalId":231556,"journal":{"name":"2016 International Conference on Systems in Medicine and Biology (ICSMB)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129759484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multi-resolution analysis to differentiate the healthy and unhealthy breast using breast thermogram","authors":"S. Pramanik, D. Bhattacharjee, M. Nasipuri","doi":"10.1109/ICSMB.2016.7915085","DOIUrl":"https://doi.org/10.1109/ICSMB.2016.7915085","url":null,"abstract":"In this study, we have proposed a novel effective method for distinguishing unhealthy breast patients from healthy individuals. It is necessary to emphasize that unhealthy breast thermograms not necessarily mean malignant. Two feature images, called magnitude features of breast thermogram (MFBT) and orientation features of breast thermogram (OFBT), are formed from the preprocessed and segmented gray scale image of breast region by computing gradient direction and orientation of each pixels. After that two multi-resolution filters are employed to represent the MFBT and OFBT at different resolutions. A 36 element feature vector is formed from the multi-resolution MFBT and OFBT images which are then classified using a feed-forward artificial neural network with gradient decent training rule. To validate the proposed method, it has been tested on 453 breast thermograms of 151 individuals (61 healthy and 90 unhealthy) of DMR database [7] and our proposed method provides excellent classification accuracy of 98.6% with the sensitivity and specificity of 100% and 97.8% respectively.","PeriodicalId":231556,"journal":{"name":"2016 International Conference on Systems in Medicine and Biology (ICSMB)","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131194871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sudipta Ghosh, Satyajit Giri, R. Kruthika, Gunit Singh Chabhra, M. Mahadevappa, J. Mukhopadhyay
{"title":"Electrical impedance plethysmography based device for aortic pulse monitoring","authors":"Sudipta Ghosh, Satyajit Giri, R. Kruthika, Gunit Singh Chabhra, M. Mahadevappa, J. Mukhopadhyay","doi":"10.1109/ICSMB.2016.7915103","DOIUrl":"https://doi.org/10.1109/ICSMB.2016.7915103","url":null,"abstract":"In this paper, we have proposed a novel design for recording aortic pulse wave using electrical impedance technique. Unlike conventional ECG, photo-plethysmography, and pulse oximetry measurements, the proposed design provides a portable, cost effective and instantaneous representation of aortic pulse wave recording. The proposed circuit design has been validated by bench testing it, using a lab standard skin model. The results obtained can be further used for determining various vital health care parameters like arterial stiffness, pulse wave velocity, etc.","PeriodicalId":231556,"journal":{"name":"2016 International Conference on Systems in Medicine and Biology (ICSMB)","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128774123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Satarupa Banerjee, S. Karri, Swarnadip Chatterjee, M. Pal, R. Paul, J. Chatterjee
{"title":"Multimodal diagnostic segregation of oral leukoplakia and cancer","authors":"Satarupa Banerjee, S. Karri, Swarnadip Chatterjee, M. Pal, R. Paul, J. Chatterjee","doi":"10.1109/ICSMB.2016.7915089","DOIUrl":"https://doi.org/10.1109/ICSMB.2016.7915089","url":null,"abstract":"Oral leukoplakia (OLK) is the most common pre malignant disorder (PMD) with highest malignant potentiality. It is clinically highly correlated with oral squamous cell carcinoma (OSCC). Painful biopsy is the gold standard till date for diagnosis of these diseases. Again for specific grading of such pathological states and mitigation of inter and intra observer variability and subjective disease classification, alternative of molecular biomarkers for diseases differentiation as well as non-invasive modalities are yet to be explored. In this study role of morphometric, intensity and textural features extracted from liquid based exfoliative cytology (LBEC) and intensity and textural features extracted from ex vivo optical coherence tomography (OCT) images and spectral features from difference between mean spectra (DBMS) were evaluated for disease classification using variants of support vector machine (SVM) classifiers. Result showed that at 10 fold cross-validation OLK and OSCC could be differentiated using cellular features of LBEC data at 100% sensitivity and specificity. Spectral biomarkers were also extracted efficiently which could classify the diseases with 81.3% sensitivity and 91.3% specificity depicting role of chemical molecules responsible in pathological alteration. Considering the advantage of each modality, it can be concluded that these features can utilized as disease differentiation markers and have useful clinical implication for diagnosis of OLK and OSCC towards mitigation of inter- as well as intra observer variability faced during routine histopathological diagnostic procedure.","PeriodicalId":231556,"journal":{"name":"2016 International Conference on Systems in Medicine and Biology (ICSMB)","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129192847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Classification of chemical skin burn using SVM method","authors":"Malini Suvarna, Venkategowda N, D. L","doi":"10.1109/ICSMB.2016.7915078","DOIUrl":"https://doi.org/10.1109/ICSMB.2016.7915078","url":null,"abstract":"The chemical burn is one of the major accidents and life treating process in the modern world. The proposed research attempts to find an automated solution for classifying chemical skin burn as superficial, partial thickness and full thickness.. The design and development of such a classifier is clinically very significant particularly, when it is used in remote areas and under emergencies. Towards achieving this aim, a database of chemical skin burn images has been created by collecting images from hospitals. The pattern analysis or pattern classifier technique called Support Vector Machine (SVM) is used in the study.","PeriodicalId":231556,"journal":{"name":"2016 International Conference on Systems in Medicine and Biology (ICSMB)","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122751595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Delay dependent analysis of respiratory system: Application to obstructive sleep apnea","authors":"Tanmay Pal, Karan Jain, S. Maka","doi":"10.1109/ICSMB.2016.7915113","DOIUrl":"https://doi.org/10.1109/ICSMB.2016.7915113","url":null,"abstract":"The respiratory system maintains homeostasis of oxygen and carbon dioxide partial pressures inside blood using feedback mechanism. Mathematical modeling of this system helps in understanding the system's properties and performance under different diseased conditions. One such situation addressed here is obstructive sleep apnea. In this condition, periodic breathing pattern is observed. It is characterized by waxing and waning of nasal airflow, which in turn makes minute ventilation oscillatory, and it is quite detrimental to the survival of a human being. In the literature, several reasons have been reported for the oscillations (gain, delay, altitude, etc.). This work is focused on Ventilatory control. Ventilation becomes oscillatory when delay posed by blood flow becomes greater than the tolerable limit. There are two chemoreceptor sites, and delay for these two locations along with their implication are different. Hence, analysis of the system for two different delays are introduced. Using LK functional method, here it is shown by analysis, that the system will become oscillatory when the delay limit crosses the specified limit during sleep. Also, it is seen that the peripheral chemoreceptors are much more susceptible to oscillation in the system.","PeriodicalId":231556,"journal":{"name":"2016 International Conference on Systems in Medicine and Biology (ICSMB)","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134588507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Classification of labour contractions using KNN classifier","authors":"R. Jyothi, S. Hiwale, Parvati Bhat","doi":"10.1109/ICSMB.2016.7915100","DOIUrl":"https://doi.org/10.1109/ICSMB.2016.7915100","url":null,"abstract":"Uterine contractions of desired strength and frequency are one of the important requirements for the smooth progress of cervical dilation and delivery of baby. Presently, Tocograph is used to monitor the strength, duration and frequency of uterine contractions. One of the major drawbacks of Tocography is subjectivity in interpretation. Therefore, there is a need for an objective method for classification of uterine contractions. In this paper, a K Nearest Neighbor based classification method is presented for automated classification of different types of uterine contractions during labour. For the study, CTG signals from Physionet database were used. The signals were annotated by an expert Doctor in three categories: mild (n=33), moderate (n=64) and strong (n=96). After processing of signals, eight features were extracted, followed by implementation of an appropriate classifier. K Nearest Neighbor and Rule based K Nearest Neighbor classifiers were used to classify the uterine contractions into mild, moderate and strong. We achieved an accuracy of 90.91%, 85% and 85.71% for classification using Rule based K Nearest Neighbor classification method.","PeriodicalId":231556,"journal":{"name":"2016 International Conference on Systems in Medicine and Biology (ICSMB)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129510694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Seismocardiography: An alternate method to estimate electro-mechanical window","authors":"P. Jain, A. Tiwari, O. Bhagat","doi":"10.1109/ICSMB.2016.7915106","DOIUrl":"https://doi.org/10.1109/ICSMB.2016.7915106","url":null,"abstract":"Analysis of electromechanical (E-M) window provides an early marker of several cardiovascular diseases. The E-M window is defined as the duration between the electrical systole (QT) and the mechanical systole (QS2). Traditional methods for the estimation of the electrical systole and the mechanical systole are electrocardiography (ECG) and phonocardiography (PCG). PCG is a widely used method due its features such as portability and cost effectiveness. However, it needs to be improvise in terms of its size and weight, to make it convenient to wear for long-term. Further, the PCG signal is susceptible to various noises, which limits its use in clinical environment. Henceforth, in this paper, we presented a novel system to estimate the E-M window using seismocardiogaphy (SCG) in replacement of the PCG. The SCG uses a sensor called accelerometer, which is small in size and low weight and hence it is convenient to wear. Furthermore, it does not require a microphone, as required in case of the PCG, and hence it is robust to environmental noises. We analysed the performance of the proposed system compared to the PCG, for the estimation of the E-M window. For this purpose ECG, PCG, and SCG signals are acquired simultaneously, for 10 subjects and then validated the obtained results using Bland-Altman plots. Results show that the proposed method is a suitable alternative to estimate the E-M window.","PeriodicalId":231556,"journal":{"name":"2016 International Conference on Systems in Medicine and Biology (ICSMB)","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128052251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shalini Singh, A. Khalid, K. Paul, Yasoob Haider, Sanjiva Prasad
{"title":"prasavGraph: An Android-based e-Partograph","authors":"Shalini Singh, A. Khalid, K. Paul, Yasoob Haider, Sanjiva Prasad","doi":"10.1109/ICSMB.2016.7915099","DOIUrl":"https://doi.org/10.1109/ICSMB.2016.7915099","url":null,"abstract":"The simplified Partograph is a concise charting mechanism used by skilled birth attendants for recording and communicating the important parameters and developments during the labour process. Compliance and correct plotting of partographs may be significantly improved with the use of technology. This paper reports the development of an Android-based smart phone/tablet application to plot the partograph. To date such a complete application is not available. We envisage that over a period of time, systematic plotting of partographs will encourage providers to use it as a decision-making tool and thereby reduce morbidity and mortality both of mother and foetus/newborn arising out of complications during labour and its sequelae.","PeriodicalId":231556,"journal":{"name":"2016 International Conference on Systems in Medicine and Biology (ICSMB)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125259118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Kernel-based feature extraction for patient-adaptive ECG beat classification","authors":"Udita Dev Roy, S. Ghorai, A. Mukherjee","doi":"10.1109/ICSMB.2016.7915108","DOIUrl":"https://doi.org/10.1109/ICSMB.2016.7915108","url":null,"abstract":"The increasing cardiac diseases of people in recent years demand an early detection of heart diseases using electrocardiogram (ECG) signal processing techniques. In this work we present a semi automatic scheme to discriminate patient-specific ECG beats by using a kernel based feature extraction technique called kernel canonical correlation analysis (KCCA). The heartbeat classification scheme uses a fixed global training set along with a local patient specific training set to produce a patient adapted training set. The performance of the KCCA features is verified on MIT-BIH arrhythmia database by using three classifiers, namely k-nearest neighbor (KNN), support vector machine (SVM) and vector valued regularized kernel function approximation (VVRKFA), to classify four different type of beats, normal (N), supra-ventricular (S), ventricular (V) and fusion of ventricular and normal (F). Experimental results show that KCCA features are more effective on normal patients than that of arrhythmia patients.","PeriodicalId":231556,"journal":{"name":"2016 International Conference on Systems in Medicine and Biology (ICSMB)","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134312889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}