发布求助
文献互助 智能选刊 最新文献

Toxicological European research. Recherche europeenne en toxicologie最新文献

筛选
英文 中文
[Phosgene poisoning]. (光气中毒)。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1983-07-01
M Fabre, F Boudet, M Boe, B Beyria, L Lareng
{"title":"[Phosgene poisoning].","authors":"M Fabre,&nbsp;F Boudet,&nbsp;M Boe,&nbsp;B Beyria,&nbsp;L Lareng","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Phosgene, a combat gaz of the first world war is now very used in industry. Authors report a few observations about acute intoxications in the manufacture of this gaz in Toulouse. They insist about the risks of slow coming out lung oedema when safety instructions are not correctly followed. However better knowledge and observance of these instructions permitted a reduction of these intoxications in number and gravity.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"5 4","pages":"185-8"},"PeriodicalIF":0.0,"publicationDate":"1983-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17424487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adult respiratory distress syndrome and silicone injection. 成人呼吸窘迫综合征和硅胶注射。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1983-07-01
J M Coulaud, J Labrousse, P Carli, M Galliot, F Vilde, J Lissac
{"title":"Adult respiratory distress syndrome and silicone injection.","authors":"J M Coulaud,&nbsp;J Labrousse,&nbsp;P Carli,&nbsp;M Galliot,&nbsp;F Vilde,&nbsp;J Lissac","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This report describes a case of adult respiratory distress syndrome (ARDS) after massive subcutaneous injections of silicone. The patient, a 23 year-old transsexual man, treated with mechanical ventilation, died on the 12th day of hospital, in septic shock and refractory hypoxemia. Autopsy findings revealed empty vacuoles surrounded by macrophages in various organs, especially in lung tissue. Toxicological analysis by emission by high frequency induced plasma showed silicone in the organs with histological lesions. The pathophysiology of this ARDS is considered.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"5 4","pages":"171-4"},"PeriodicalIF":0.0,"publicationDate":"1983-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17720665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Lung injury after use of respiratory revival materials sterilized with ethylene oxide]. [使用环氧乙烷灭菌呼吸再生材料后肺损伤]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1983-05-01
A Castot, G Riboulet-Delmas, M L Efthymiou, D Robardey, F Manela, O Muzard, A Goldstein
{"title":"[Lung injury after use of respiratory revival materials sterilized with ethylene oxide].","authors":"A Castot,&nbsp;G Riboulet-Delmas,&nbsp;M L Efthymiou,&nbsp;D Robardey,&nbsp;F Manela,&nbsp;O Muzard,&nbsp;A Goldstein","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>One of the most used method of medical appliances sterilization uses ethylene oxide. At high concentration, this very reactive product, causes caustic burns of skin and mucous membranes. In one case of acute pulmonary oedema, levels of ethylene oxide in the endotracheal catheter were discovered. This led us to review the toxicological data on this substance. It should be emphasized that the sterilization and the desorption according to simple and precise rules should prevent such acute accidents.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"5 3","pages":"127-30"},"PeriodicalIF":0.0,"publicationDate":"1983-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17691041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Neurotoxicity of pyrethrins in warm-blooded animals]. [除虫菊酯对温血动物的神经毒性]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1983-05-01
F Souyri, H Hoellinger
{"title":"[Neurotoxicity of pyrethrins in warm-blooded animals].","authors":"F Souyri,&nbsp;H Hoellinger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The synthetic pyrethroids, a new class of insecticides, have excellent insecticide properties with good biodegradability, therefore a low remanence. Their mammalian toxicity is low in considering amounts used in agriculture. On the other hand, experimental animals exposed to mean so high concentrations of pyrethroids display neurological symptoms. This paper is a review relating the electrophysiological, biochemical and pharmacological aspect of the patent neurotoxicity of pyrethroids. Benign cases human intoxication and acute animal intoxication are reported.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"5 3","pages":"103-12"},"PeriodicalIF":0.0,"publicationDate":"1983-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17417490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Deliberate poisoning with paraquat, death in less than 24 hours]. [故意用百草枯中毒，24小时内死亡]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1983-05-01
F Barale, P Singer, A Xicluna, F Arbez-Gindre
{"title":"[Deliberate poisoning with paraquat, death in less than 24 hours].","authors":"F Barale,&nbsp;P Singer,&nbsp;A Xicluna,&nbsp;F Arbez-Gindre","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This paper describes a case of deliberate massive ingestion of Paraquat (over 300 mg/Kg). Evolution is toward a circulatory insufficiency with metabolic acidosis, hyperglycemia, and early death (18 hours). Severe pulmonary failure would have been expected, but not appeared. Autopsy revealed patchy necrosis of the liver but no severe damage of the other organs, including lung and adrenal.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"5 3","pages":"123-6"},"PeriodicalIF":0.0,"publicationDate":"1983-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17691040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Inhalation pneumonia in toxic comas. Apropos of 200 cases with 4 deaths]. 中毒性昏迷的吸入性肺炎。约200例，其中4例死亡]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1983-05-01
J Pham, C Bismuth, F Baud, P G Pontal, A Bolo, R Surugue, M Elkhouly
{"title":"[Inhalation pneumonia in toxic comas. Apropos of 200 cases with 4 deaths].","authors":"J Pham,&nbsp;C Bismuth,&nbsp;F Baud,&nbsp;P G Pontal,&nbsp;A Bolo,&nbsp;R Surugue,&nbsp;M Elkhouly","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 1946, Mendelson described 66 cases of gastric juice inhalation during obstetrical work with no mortality. Other studies studying different populations (essentially in post-operative condition) denounced a mortality from 19 to 64%. In Forensic Medicine, a bronchial regurgitation of gastric juice is denounced in 1/3 lethal toxic comas. This regurgitation can be the direct cause of the death, it also can be an epiphenomena, as suggests the high level of inhalation in agonic process of any cause: 1/4 of autopsy findings. In our department, 200 cases of inhalation pneumonia, during comatose intoxications have been registered between 1972-1982, with a frequency of 1/28 patients. All the patients were under assisted ventilation. 4 deaths occurred in this serie. This 2% mortality suggests the curability of gastric juice inhalation during comatose intoxications in not specifically respiratory-orientated intensive Care Units. These relatively good results are probably party related to the patients' recruitment: young population without underlying organic disease, with a rapid turnover and little hazards of nosocomial superinfections.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"5 3","pages":"117-22"},"PeriodicalIF":0.0,"publicationDate":"1983-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17691189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pulmonary toxicity of bleomycin in the rabbit: histophysiological and anatomo-radiological correlations]. [博来霉素对兔肺毒性:组织生理学和解剖学相关性]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1983-05-01
M Bellet-Barthas, J P Le Roy, L Barthelemy, M Bellet
{"title":"[Pulmonary toxicity of bleomycin in the rabbit: histophysiological and anatomo-radiological correlations].","authors":"M Bellet-Barthas,&nbsp;J P Le Roy,&nbsp;L Barthelemy,&nbsp;M Bellet","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This work was made to study the eventual modifications of breathing pattern induced by an experimental interstitial fibrosis. In this aim, breathing pattern and lung radiology from 6 rabbits have been studied at different times (1, 3, 7, 15, 20, 45 days) after an intratracheal infusion of Bleomycin (7 U.kg-1). At the end of each observation period, a rabbit was killed and prepared for a pathologic study (light and electronic microscopy). Despite the early interstitial and alveolar radiologic syndrome, there is no significant modification of the breathing pattern. However the histologic study is in agreement with the radiologic pictures and reveals an early development of large exsudative injury with hyaline membranes, interstitial and alveolar oedema. The alterations trend to an interstitial diffuse fibrosis. The absence of correlations between the physiological and histological events is discussed.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"5 3","pages":"113-6"},"PeriodicalIF":0.0,"publicationDate":"1983-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17259373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Acute paraquat poisoning: prognostic and therapeutic significance of blood assay]. [急性百草枯中毒:血液测定的预后和治疗意义]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1983-05-01
J M Scherrman, M Galliot, R Garnier, C Bismuth
{"title":"[Acute paraquat poisoning: prognostic and therapeutic significance of blood assay].","authors":"J M Scherrman,&nbsp;M Galliot,&nbsp;R Garnier,&nbsp;C Bismuth","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors describe a high correlation between the plasma and urine Paraquat concentrations in 45 poisoned patients. The study of the plasma and urine kinetics asserts the importance and the rapidity of distribution processes and how it is necessary to quickly undertake the therapeutic means.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"5 3","pages":"141-5"},"PeriodicalIF":0.0,"publicationDate":"1983-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17691043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[In vitro dissolution of metallic oxides in human plasma and binding of metals to plasma proteins--effect of chelators]. [金属氧化物在人血浆中的体外溶解和金属与血浆蛋白的结合——螯合剂的作用]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1983-05-01
M Frenet, F Vincent, H L Boiteau
{"title":"[In vitro dissolution of metallic oxides in human plasma and binding of metals to plasma proteins--effect of chelators].","authors":"M Frenet,&nbsp;F Vincent,&nbsp;H L Boiteau","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The solubility in biological liquids of oxides is one of the factors which determinate the speed of penetration into the blood stream of toxic agents contained in solid particles inside pulmonary alveoli. This solubility was studied in vitro for the six following metal oxides: Cd, Cr, Fe, Mn, Pb, Zn, by holding particle oxides in suspension into human plasma at 37 degrees C, during variable time. The experimentation was realized on particles which belong to two categories which sizes are 0.45-2 and 2-5 mu. The evolution of metal oxide dissolved level according to time have enabled exponential relation parameters to be calculated. These parameters translate the particle oxide dissolution into plasma and have permitted to classify metal oxide in decreasing solubility order: Cd, Zn, PbO, Fe2O3, Fe3O4, Mn, PbO2, Pb3O4 and Cr2O3. The second part of the experimentation is about dissolved metal distribution between the different protein fractions. Dissolved metal is distributed between diffusible metal (lower than 10 per cent) and metal binding proteins chiefly in albumin except for Fe which is bound to transferrin. Chelating agents into plasma reduce the proportion of metals bound to proteins. EDTA Ca is energetic on all metals mainly on Lead, Cadmium, and Zinc. N-acetyl-DL penicillamin is less energetic. Meso 2,3 dimercapto succinic acid, and 2,3 dimercapto-1-propan sulfonic acid have an effect only on Lead but in a very light way. Desferrioxamin release a great proportion of Iron bound to proteins. These results, obtained in vitro, are similar to those from animal experimentation or those observed in human therapeutic.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"5 3","pages":"131-9"},"PeriodicalIF":0.0,"publicationDate":"1983-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17691042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Lung diseases complicating acute poisoning with psychotropic drugs]. [肺部疾病并发急性精神药物中毒]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1983-03-01
G Offenstadt, J M Gabillet, P Hericord, P Pinta, A Tembely, P Amstutz
{"title":"[Lung diseases complicating acute poisoning with psychotropic drugs].","authors":"G Offenstadt,&nbsp;J M Gabillet,&nbsp;P Hericord,&nbsp;P Pinta,&nbsp;A Tembely,&nbsp;P Amstutz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>474 patients admitted in ICU between 1976 and 1981 were retrospectively analysed. Pneumonia (P) was assessed by condensation on chest X ray. P developed in 14,3%. 24 hours after admission 77,6% of P had appeared. Initial location was unilateral in 79,4% with predilection to the inferior half of the right lung. Fever was almost constant (89,5%). Promoting factors were observed: delay between ingestion and admission, vomiting and tracheobronchial embarrassment, coma depth. Recovery was simple in 83,3%. Among the 14 deads, 6 died because only of p, in 4 other P was aggravating. Duration in ICU was much longer when P was present (9 +/- 8,1 days) than when P was absent (2,5 +/- 2,1) p less than 0,001.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"5 2","pages":"85-8"},"PeriodicalIF":0.0,"publicationDate":"1983-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17668426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信