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Toxicological European research. Recherche europeenne en toxicologie最新文献

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[Study of three biocides (dimethoate, parathion ethyl and zineb) on female rat neuro endocrinological balance (author's transl)]. [三种杀生剂(乐果、对硫磷乙基和锌)对雌性大鼠神经内分泌平衡的影响[作者译]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1981-11-01
D Bentue-Ferrer, H Allain, J M Reymann, J Van den Driessche
{"title":"[Study of three biocides (dimethoate, parathion ethyl and zineb) on female rat neuro endocrinological balance (author's transl)].","authors":"D Bentue-Ferrer,&nbsp;H Allain,&nbsp;J M Reymann,&nbsp;J Van den Driessche","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors studied the neuro endocrinological effects of three pesticides. Two of them were organophosphorus compounds (ethyl parathion and dimethoate) and one was a carbamate (zineb). Mature female rats have been orally administered these compounds for 16 days at respectively 1/25, 1/10 and 1/10 of the LD50. The parameters recorded are: the gonadotropins, the length of estrous cycle and the weight of the anterior pituitary gland, the ovaries and the uterus. In contradistinction with the organochlorine compounds the organophosphorus did not induce any disturbances in the neuro endocrinological system, whereas the carbamate compound decreased the pituitary gonadotropins.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"3 6","pages":"279-83"},"PeriodicalIF":0.0,"publicationDate":"1981-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17852138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute toluene poisoning. Electroneurophysiological and vestibular investigations. 急性甲苯中毒。电子神经生理学和前庭检查。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1981-11-01
G P Biscaldi, M Mingardi, G Pollini, A Moglia, M C Bossi
{"title":"Acute toluene poisoning. Electroneurophysiological and vestibular investigations.","authors":"G P Biscaldi,&nbsp;M Mingardi,&nbsp;G Pollini,&nbsp;A Moglia,&nbsp;M C Bossi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Neurophysiological studies were carried out in six female workers of an electromechanical works after accidental exposure to toluene vapours. Electroencephalographic abnormalities and vestibular hyporeflexia were detected immediately after the accident. Six months later the EEG changes were still present, while vestibular findings were found to be markedly improved. Results of this study provide further evidence of the diagnostic value of vestibular investigations after toxic exposure to toluene.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"3 6","pages":"271-3"},"PeriodicalIF":0.0,"publicationDate":"1981-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18025131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Mercury and methylmercury pollution of fishery products. Toxicological effects on human health (author's transl)]. [渔业产品的汞和甲基汞污染。]对人类健康的毒理学影响[作者译]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1981-09-01
G Gras, J Mondain
{"title":"[Mercury and methylmercury pollution of fishery products. Toxicological effects on human health (author's transl)].","authors":"G Gras,&nbsp;J Mondain","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Since the japanese mass poisoning in 1954's, classically named today \"Minamata disease\", mercury and its derivatives occupy a place of choice into the most worrying chemical pollutants for the human health and a lot of studies about the pathways by which mercury enters in its biogeochemical cycle or the environmental mercury levels are resumed in this paper. The most important aspects of mercury ecotoxicology are reviewed here: biological methylation reaction, bioaccumulation and biomagnification of these toxics in te aquatic ecosystems. The authors also describe the mercury and methylmercury metabolism and the symptomatology of the methylmercurial poisoning; with emphasis that infraclinic chronical manifestations, or large epidemiological interest, are not well known. It should be necessary to found a sensitive biochemical test, specific of this intoxication. The studies about the initial body burden assessment or the threshold values of mercury in easily obtainable specimens (blood hair) are only available for a statistical distribution. At individual levels, a number of factors occur, particularly the presence of selenium who should act as a biological antagonist of methylmercury.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"3 5","pages":"243-59"},"PeriodicalIF":0.0,"publicationDate":"1981-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18349508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethanol preference as a function of genotypic levels of whole brain enkephalin in mice. 乙醇偏好与小鼠全脑脑啡肽基因型水平的关系。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1981-09-01
K Blum, A H Briggs, S F Elston, L DeLallo
{"title":"Ethanol preference as a function of genotypic levels of whole brain enkephalin in mice.","authors":"K Blum,&nbsp;A H Briggs,&nbsp;S F Elston,&nbsp;L DeLallo","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"3 5","pages":"261-2"},"PeriodicalIF":0.0,"publicationDate":"1981-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18353782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Determination of low levels of diethylcarbamoyl chloride in air. First results after inhalation in rat (author's transl)]. [空气中低浓度二乙基氨基甲酰氯的测定。大鼠吸入后的初步结果[作者简介]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1981-09-01
J P Anger, J C Corbel, G Paulet
{"title":"[Determination of low levels of diethylcarbamoyl chloride in air. First results after inhalation in rat (author's transl)].","authors":"J P Anger,&nbsp;J C Corbel,&nbsp;G Paulet","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"3 5","pages":"223-8"},"PeriodicalIF":0.0,"publicationDate":"1981-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18349506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effects of the contamination by polychlorobiphenyls (PCBs) on the growth of the Ehrlich tumor in mice (author's transl)]. [多氯联苯(PCBs)污染对小鼠埃利希瘤生长的影响[作者译]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1981-09-01
G Keck
{"title":"[Effects of the contamination by polychlorobiphenyls (PCBs) on the growth of the Ehrlich tumor in mice (author's transl)].","authors":"G Keck","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effects of a 3-month experimental contamination with a commercial mixture of PCBs, DP5 (corresponding to Aroclor 1254) have been studied on groups of 25 SWISS female mice, at levels of 0, 10, 50 and 250 ppm added at feeding. After subcutaneous injection of 0,2 ml of Ehrlich's tumoral ascites liquid, the evolution of tumors as well as the mortality level, were different in the treated groups as compared to the control group. The percentages of mortality due to tumors were the following: control (0 ppm) = 50% 10 ppm = 5% 50 ppm = 5% 250 ppm = 35% Thus, contamination by PCBs seems to have protected these mice against the Ehrlich tumor. No decrease in body weight was noted neither were differences in size or appearance of the thymus and the spleen in the treated mice; an evident liver hypertrophy was noted in all PCB treated mice.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"3 5","pages":"229-36"},"PeriodicalIF":0.0,"publicationDate":"1981-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17856251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Studies on the influence of fluoride compounds upon connective tissue metabolism in growing rats. I. Effect of hydrofluoride on collagen metabolism. 氟化物对生长大鼠结缔组织代谢影响的研究。1 .氢氟化物对胶原代谢的影响。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1981-09-01
M Drózdz, E Kucharz, E Grucka-Mamczar
{"title":"Studies on the influence of fluoride compounds upon connective tissue metabolism in growing rats. I. Effect of hydrofluoride on collagen metabolism.","authors":"M Drózdz,&nbsp;E Kucharz,&nbsp;E Grucka-Mamczar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Female rats were exposed to hydroxyfluoride (2.7 mg/m3 or 5.0 mg/m3) seven weeks before pregnancy during pregnancy and lactation as well as subsequently with the offsprings up to 1, 2, 4 and 6 months after birth. The offspring was taken for investigations. It was found that serum hydroxyproline and hydroxylysine was elevated in growing rats exposed to hydrofluoride. The elevation was higher in animals inspired to 5.0 mg/m3 than in rats treated with 2.7 mg/m3. One- and two-months old rats were shown to be more suitable to hydrofluoride. Similar changes were observed in urinary excretion of these compounds. Changes in collagen content were found in skin and lungs. A marked decrease total collagen content and changes in collagen fractions were shown.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"3 5","pages":"237-41"},"PeriodicalIF":0.0,"publicationDate":"1981-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18349507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Considerations on the epidemiology of the Seveso accident. 关于Seveso事故流行病学的思考。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1981-09-01
B Terracini
{"title":"Considerations on the epidemiology of the Seveso accident.","authors":"B Terracini","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"3 5","pages":"262-3"},"PeriodicalIF":0.0,"publicationDate":"1981-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18353783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative studies by scanning electron microscopy of the effect of ricin on the cell membrane of hepatoma cells and isolated hepatocytes. 扫描电镜下蓖麻毒素对肝癌细胞和离体肝细胞细胞膜影响的比较研究。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1981-07-01
E E Creppy, A A Lugnier, G Beck, G Dirheimer, E Petzinger, M Frimmer
{"title":"Comparative studies by scanning electron microscopy of the effect of ricin on the cell membrane of hepatoma cells and isolated hepatocytes.","authors":"E E Creppy,&nbsp;A A Lugnier,&nbsp;G Beck,&nbsp;G Dirheimer,&nbsp;E Petzinger,&nbsp;M Frimmer","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"3 4","pages":"179-84"},"PeriodicalIF":0.0,"publicationDate":"1981-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18314549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inhibition of macrophage migration by ochratoxin A and citrinin, and prevention by phenylalanine of the ochratoxin A-induced inhibition. 赭曲霉毒素A和柠檬霉素对巨噬细胞迁移的抑制作用，以及苯丙氨酸对赭曲霉毒素A诱导的抑制作用的预防作用。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1981-07-01
W Klinkert, G Lorkowski, E E Creppy, G Dirheimer, R Röschenthaler
{"title":"Inhibition of macrophage migration by ochratoxin A and citrinin, and prevention by phenylalanine of the ochratoxin A-induced inhibition.","authors":"W Klinkert,&nbsp;G Lorkowski,&nbsp;E E Creppy,&nbsp;G Dirheimer,&nbsp;R Röschenthaler","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"3 4","pages":"185-9"},"PeriodicalIF":0.0,"publicationDate":"1981-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18314550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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