中毒性昏迷的吸入性肺炎。约200例,其中4例死亡]。

J Pham, C Bismuth, F Baud, P G Pontal, A Bolo, R Surugue, M Elkhouly
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引用次数: 0

摘要

1946年,Mendelson报告了66例产科工作中吸入胃液的病例,无死亡病例。其他针对不同人群(主要是术后状态)的研究表明死亡率在19%到64%之间。在法医学上,1/3的致死性中毒性昏迷中有胃液支气管反流。这种反流可能是死亡的直接原因,也可能是一种附带现象,因为在任何原因的死亡过程中都有大量吸入:尸检结果的1/4。在1972-1982年期间,我科共记录了200例昏迷中毒期间的吸入性肺炎,发病率为1/28。所有患者均在辅助通气下。在这个系列中有4人死亡。2%的死亡率表明,在非呼吸导向的重症监护病房中,昏迷中毒时吸入胃液是可以治愈的。这些相对较好的结果可能与患者招募有关:年轻人群无潜在器质性疾病,更替快,院内重复感染的危险小。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Inhalation pneumonia in toxic comas. Apropos of 200 cases with 4 deaths].

In 1946, Mendelson described 66 cases of gastric juice inhalation during obstetrical work with no mortality. Other studies studying different populations (essentially in post-operative condition) denounced a mortality from 19 to 64%. In Forensic Medicine, a bronchial regurgitation of gastric juice is denounced in 1/3 lethal toxic comas. This regurgitation can be the direct cause of the death, it also can be an epiphenomena, as suggests the high level of inhalation in agonic process of any cause: 1/4 of autopsy findings. In our department, 200 cases of inhalation pneumonia, during comatose intoxications have been registered between 1972-1982, with a frequency of 1/28 patients. All the patients were under assisted ventilation. 4 deaths occurred in this serie. This 2% mortality suggests the curability of gastric juice inhalation during comatose intoxications in not specifically respiratory-orientated intensive Care Units. These relatively good results are probably party related to the patients' recruitment: young population without underlying organic disease, with a rapid turnover and little hazards of nosocomial superinfections.

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