One Health and Nutrition Problems of Ukraine最新文献

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Nutrient correction of the clinical course and alimentary prevention of the tuberculous infection effects 营养矫正对临床病程及消化道预防结核感染的作用
One Health and Nutrition Problems of Ukraine Pub Date : 2023-01-09 DOI: 10.33273/2663-9726-2022-57-2-63-81
I. Matasar, R. H. Protsiuk, I.O. Halan
{"title":"Nutrient correction of the clinical course and alimentary prevention of the tuberculous infection effects","authors":"I. Matasar, R. H. Protsiuk, I.O. Halan","doi":"10.33273/2663-9726-2022-57-2-63-81","DOIUrl":"https://doi.org/10.33273/2663-9726-2022-57-2-63-81","url":null,"abstract":"Abstract. Food is a source of flexible, energetic and catalytical ingredients that stipulate the human organism’s life and development. Proteins on a par with other nutrients, form tissues, are a part of enzymes, hormones, participate in the processes of growth, development and restoration of organs and systems.\u0000\u0000The Aim. To scientifically substantiate the correction measures of the clinical course and alimentary prevention of complications caused by tuberculous infection. To list up the main sources of nutrients, to show their importance for the tuberculous infection course correction and the effect of essential substances on the prevention of complications caused by the disease.\u0000\u0000Materials and Methods. The complex of theoretical, empirical methods and full-scale observations was used for the investigation. Theoretical research methods were: bibliographic analysis, synthesis and abstraction, as well as generalization of available in scientific literature data and their classification and systematization. The methods of empirical research were traditional modern approaches: full-scale observations, interviews, polling, questionnaires, and expert evaluation. Methods of biological research: epidemiological, clinical, laboratory, physical-chemical, biochemical and medical-statistical.\u0000\u0000Results and Conclusions. The quality of the dietary structure was determined by the complex of amino acids, fatty acids, especially omega-3 PUFAs, vitamins, minerals, and the sufficiency of complex carbohydrates that stimulate intestinal peristalsis, which was important in a sedentary lifestyle. The actual food quality effect on the body’s supply of alimentary iron was described. The impact of the latter on the disease course was distinguished. It was shown that the excess of energy caused by the excessive simple sugars consuming, contributed to the exacerbation of the disease course and allergies. It was emphasized that the energy value of the diet should depend on the peculiarities of the disease course, the presence of associated complication, the patient’s body weight, as well as the type of work with preserved performance efficacy.\u0000\u0000Key Words: nutrient correction, essential substances, ideal protein, amino acids, recommended daily intake, food products, energy value of the diet, principles of the diet therapy, erythrocytes, lymphocytes, leukogram.","PeriodicalId":231282,"journal":{"name":"One Health and Nutrition Problems of Ukraine","volume":"283 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129992944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research of peculiarities of consumption of low-alcohol beverages by children and adolescents in Ukraine and identification of risks to public health 研究乌克兰儿童和青少年饮用低酒精饮料的特点和确定对公共健康的风险
One Health and Nutrition Problems of Ukraine Pub Date : 2023-01-09 DOI: 10.33273/2663-9726-2022-57-2-26-40
O. Lutsenko, N. Horban, T.Yu. Safir, M. Zinovieva, N. Kurdil
{"title":"Research of peculiarities of consumption of low-alcohol beverages by children and adolescents in Ukraine and identification of risks to public health","authors":"O. Lutsenko, N. Horban, T.Yu. Safir, M. Zinovieva, N. Kurdil","doi":"10.33273/2663-9726-2022-57-2-26-40","DOIUrl":"https://doi.org/10.33273/2663-9726-2022-57-2-26-40","url":null,"abstract":"Abstract. Recently, the problem of low-alcohol consumption among adolescents and young people has become especially relevant, which was confirmed by the results of global WHO research and the ESPAD project in Ukraine (2019).\u0000\u0000Aim. Study the age and gender characteristics of low-alcohol beverages among children and adolescents, identify risks and identify ways to minimize the negative impact of low-alcohol beverages on public health.\u0000\u0000Materials and Methods. The data of the WHO and the ESPAD project, separate national researches on alcohol use by teenagers are studied; analyzed the results of the long-term epidemiological study \"Family and Children of Ukraine\", which is part of the WHO long-term European long-term study program on parenting and childhood \"ELSPAC\" (European Longitudinal Study of Parenthood and Childhood).\u0000\u0000Results. According to the latest ESPAD study in Ukraine (2019), 85.7 % of all adolescents surveyed (more than 2,000 people) have consumed alcohol at least once in their lifetime, and the share of those who have consumed alcohol in their lifetime is ten and more times amounted to 46.3 %. According to the Family and Children of Ukraine study (989 people), the youngest age when alcohol was first consumed by adolescents of both sexes was 9 years of age and younger, with adolescent girls being more active than boys in their age. The analysis of the questionnaires (\"Adolescent Questionnaires 15-18 years\") revealed that among the surveyed adolescents, 67.4 % (725) people drank alcohol at least once in their lives, and there were more girls (69.5 % – 370 people) than boys (65.4 % – 355 people). The highest rates among adolescent boys were recorded in the 14-year-old group: 19.0 % drank beer for the first time, 14.5 % drank wine or champagne, 9.4% drank alcohol, and 7.4% drank strong alcohol. The highest rates of adolescent girls were found in the 15-year age group: beer was consumed for the first time by 16.9%, wine or champagne – 22.4%, alcoholic cocktail – 16.9 %, spirits – 8.6 %. Analysis of the degree of involvement of adolescents in beer consumption showed that at the age of 9 years and younger 3.9% (21) boys and 5.3 % (28) girls tried beer for the first time; at the age of 14 – 19.0 % (103) boys and 14.5 % (77) girls; at the age of 15 – 16.0 % (87) boys and 16.9 % (90) girls. Thus, the first time the interviewed teenagers tried beer was at the age of 14-15.\u0000\u0000Conclusions. Consumption of low-alcohol beverages among children and adolescents in Ukraine is an acute social problem, the solution of which requires a systematic approach, which should include the formation and promotion of alcohol-free norms among young people, as well as marketing tools focus on priority consumption of soft drinks.\u0000\u0000Key Words: low alcohol drinks, adolescents, food safety.","PeriodicalId":231282,"journal":{"name":"One Health and Nutrition Problems of Ukraine","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122717475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of the degree of danger of waste galvanic elements (batteries) 废旧原电元件(电池)危险程度的测定
One Health and Nutrition Problems of Ukraine Pub Date : 2023-01-09 DOI: 10.33273/2663-9726-2022-57-2-82-97
S. Snoz, L.М. Smerdova, A. H. Kudriavtseva, A. A. Kalashnikov, O. Bobyliova
{"title":"Determination of the degree of danger of waste galvanic elements (batteries)","authors":"S. Snoz, L.М. Smerdova, A. H. Kudriavtseva, A. A. Kalashnikov, O. Bobyliova","doi":"10.33273/2663-9726-2022-57-2-82-97","DOIUrl":"https://doi.org/10.33273/2663-9726-2022-57-2-82-97","url":null,"abstract":"Abstract. In recent decades, the world has faced a new environmental problem ‒ waste electrical and electronic equipment (WEEE). Timely prevention of the formation of WEEE, minimization of their volume, reuse, recycling and recovery of resources ‒ all these issues require urgent appropriate solutions.\u0000\u0000Aim. Determining the degree of hazard of waste galvanic elements (batteries) and assigning this waste to the category of hazardous or safe according to national norms and rules.\u0000\u0000Materials and Methods. Waste galvanic cells (batteries) were the object of research. The samples were dissolved in concentrated nitric acid. The solutions were diluted with distilled water, filtered, and then the content of heavy metals was determined according to DSTU ISO 11885:2005 \"Water quality. 33 elements were determined by the method of atomic emission spectrometry with inductively coupled plasma\" (ISO 11885:1996, IDT) and GOST 30178-96 \"Raw materials and food products. Atomic absorption method for determination of toxic elements\". Determination of elements was carried out on an optical emission spectrometer with an inductively coupled plasma \"SHIMADZU ICPE-9820\".\u0000\u0000Research results. It was established that the content of lead, cadmium, mercury in waste galvanic elements (batteries) does not exceed the established hygienic standards for the soil (\"Hygienic regulations of the permissible content of chemical substances in the soil\", Order of the Ministry of Health of Ukraine No. 1595 dated 14.07.2020). Mercury: in 25 samples it was detected at a level that is lower than the sensitivity of the method, in two samples it is 2.25 times and 4.2 times less than the Limit Permissible Concentrations (LPC); in four ‒ 27-48.8 times less, in three ‒ 58-91 times less. The LPC of mercury in soil is 2.1 mg/kg. Cadmium: in 1 sample it was detected at a level that is lower than the sensitivity of the method, in 26 samples it is 2-7.5 times less than the LPC; in the 7th ‒ 9-30 times less. The LPC of cadmium in soil is 1.5 mg/kg. Lead: in 13 samples it was detected at a level that is lower than the sensitivity of the method, in 2 samples it was 3 times less than the LPC, in 6 samples it was 12-19.4 times less than the LPC, in 13 samples ‒ in 24-31 times less than LPC. Maximum permissible limit for lead in soil is 32 mg/kg. It was established that the examined waste samples of galvanic elements (batteries) can be classified as safe and processed and disposed of at the appropriate enterprise.\u0000\u0000Conclusions. The negative effect of WEEE components on the environment and, as a result, on human health is associated with the inevitable risk of their entering environmental objects due to improper handling of waste galvanic elements (batteries). In order to prevent and minimize the risk to the environment and the population, it is necessary to introduce selective sorting of WEEE components at the places of their generation or collection and sending them for processing, as well as to develop sanit","PeriodicalId":231282,"journal":{"name":"One Health and Nutrition Problems of Ukraine","volume":"161 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132121801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Practical aspects of using extracorporal detoxification methods in the treatment of acute chemical poisoning 体外解毒方法在急性化学中毒治疗中的实际应用
One Health and Nutrition Problems of Ukraine Pub Date : 2023-01-09 DOI: 10.33273/2663-9726-2022-57-2-98-109
N. Kurdil, V. Andriuschenko
{"title":"Practical aspects of using extracorporal detoxification methods in the treatment of acute chemical poisoning","authors":"N. Kurdil, V. Andriuschenko","doi":"10.33273/2663-9726-2022-57-2-98-109","DOIUrl":"https://doi.org/10.33273/2663-9726-2022-57-2-98-109","url":null,"abstract":"Abstract. The structure of xenobiotics that cause poisoning and the need for hospitalization is constantly changing. Today, psychotropic and narcotic substances and their precursors have become the main cause of severe poisonings that require emergency medical care. At the same time, another problem is the combined use of narcotic substances and alcohol, which often causes multiorgan dysfunction and prompts doctors to search for new treatment approaches, using traditional methods of afferent and efferent therapy in combination with modern extracorporeal detoxification technologies.\u0000\u0000Aim. Study of the peculiarities of the use of extracorporeal detoxification methods in the treatment of patients with acute chemical poisoning, which are associated with the change in the structure of poisons for 1990-2020.\u0000\u0000Materials and Methods. A cohort retrospective analysis of 1,685 charts of hospitalized patients with acute poisoning (Form No. 003/0) and 5,025 protocols of artificial detoxification procedures was conducted. Data from the reports of the Toxicological department and the Intensive care and extracorporeal detoxification unit of the Kyiv City Clinical Emergency Medical Center (hereinafter referred to as the Toxicological Center) for the period 1990-2020, with information on the structure of medical technologies (membrane, centrifugal, sorption and other) and the number of artificial detoxification methods used during the study period.\u0000\u0000Results. On average, the Kyiv Toxicological Center provides medical care to about 2,500 adult patients with chemical poisonings per year, of which about 1,500 patients will receive assistance in the Intensive care and extracorporeal detoxification unit. About 64,000 patients were treated in the period 1990-2020. It was established that the structure of acute poisonings has undergone significant changes: the number of poisonings by pesticides (organophosphorus substances, carbamates, and pyrethroids), technical fluids and solvents (ethylene glycol, dichloroethane, hydrogen tetrachloride, and methanol), metals (lead, mercury), corrosive substances (acids, alkalis). At the same time, a significant number of poisonings with alcohol and its surrogates, plant toxins and mushrooms, and household chemicals remained. The share of domestic, suicidal and criminal drug poisonings increased. However, after 2015, the number of poisonings by drugs, psychotropic substances (methadone, heroin, synthetic opioids) and their precursors, including in combination with benzodiazepines, meth- and amphetamine, cocaine and ethanol, has increased rapidly. In general, the part of drug poisonings has increased 3.5 times over the past 30 years. In accordance with the change in the structure of acute poisoning, the structure of extracorporeal detoxification technologies has also gradually undergone changes. The annual number of sorption technologies (hemosorption, plasmasorption) decreased. At the same time, there was an increase in the number of ce","PeriodicalId":231282,"journal":{"name":"One Health and Nutrition Problems of Ukraine","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122814497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wood-based composite building materials: safety assessment in Ukraine and the EU technical regulation system 木基复合建筑材料:乌克兰与欧盟技术法规体系的安全评估
One Health and Nutrition Problems of Ukraine Pub Date : 2023-01-09 DOI: 10.33273/2663-9726-2022-57-2-7-25
M. Prodanchuk, T. Oboronova, O. Bobyliova, N.Ye. Dyshinevich, O.L. Pereguda, A. A. Kalashnikov
{"title":"Wood-based composite building materials: safety assessment in Ukraine and the EU technical regulation system","authors":"M. Prodanchuk, T. Oboronova, O. Bobyliova, N.Ye. Dyshinevich, O.L. Pereguda, A. A. Kalashnikov","doi":"10.33273/2663-9726-2022-57-2-7-25","DOIUrl":"https://doi.org/10.33273/2663-9726-2022-57-2-7-25","url":null,"abstract":"Abstract. Composite building materials based on wood (further ‒ wood plastics) remain a key object of sanitary and hygienic research as an important source of marker air pollutants in residential premises.\u0000\u0000Aim. Generalization of the results of sanitary and hygienic studies of wood plastics that are in circulation on the market of Ukraine; comparative analysis of individual provisions of the system of technical regulation of the specified products in the EU and Ukraine.\u0000\u0000Materials and Methods. Directives of EU countries in the field of technical regulation of chemically hazardous construction materials and sanitary legislation of Ukraine; data of sanitary-hygienic researches of the air of residential premises based on complaints of residents of the city of Kyiv, carried out by the \"Kyiv City Center for Disease Control and Prevention of the Ministry of Health of Ukraine\" (2010-2019); the results of chamber studies of samples (N=4859) of building products based on wood plastics and furniture, performed in the polymer hygiene laboratory of the State Enterprise \"L.I. Medved’s Research Center of Preventive Toxicology, Food and Chemical Safety of the Ministry of Health of Ukraine\" (2010-2019). Statistical analysis ‒ Microsoft Excel 2019.\u0000\u0000Results. According to the research data of wood-plastic samples, a high level of their compliance with technical requirements and quality parameters and hygienic standards of Ukraine was established, so over the 10 years of research, the average deviations were: glued plywood, veneered panels, other laminated wood materials - 3.59% (n=1234); fiberboard boards made of wood or other wood materials with or without the addition of resins or other substances ‒ 1.36% (n=1512); chipboard boards, with oriented chips and similar boards (for example, wafer boards) ‒ 1.73% (n=1441); furniture samp-les – 1.6% (n=672). At the same time, an increase in the number of cases of exceeding the concentration of phenol and formaldehyde in relation to the MPC average daily in the air of residential premises of multi-apartment buildings during the same period was found: phenol by 2.86 times (R2=0.764), formaldehyde by 2.7 times (R2=0.529). The difference between wood-plastic samples sent for sanitary-hygienic research and those products that enter residential premises is not excluded, and cases of wood-plastic use in residential premises that are not intended are also found. Fundamental differences in the approaches of the EU and Ukraine to the assessment of the safety of composite building materials still remain unsettled. Difficulties in adapting the product safety regulatory system in the EU for introduction in Ukraine are due to the methodology of risk assessment for human health as a key tool for substantiating product and commodity safety standards. The main distinguishing feature of the EU legal framework on this issue is the recognition of product safety based on the absence of unacceptable risk, and the methodology that was impleme","PeriodicalId":231282,"journal":{"name":"One Health and Nutrition Problems of Ukraine","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131342153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Promising directions for the development of means that can increase the adaptation capabilities of the human body under the conditions of the negative influence of the life environment 有希望的发展方向是指能够提高人体在生活环境负面影响条件下的适应能力
One Health and Nutrition Problems of Ukraine Pub Date : 2023-01-09 DOI: 10.33273/2663-9726-2022-57-2-41-62
A. Kalashnikov, N. Kurdil, O.O. Khudaykulova, O.S. Zulfiharov, H. Petrashenko, V. P. Atamaniuk, P. Zhminko, A. Hrynko, A. O. Zulfiharov, I. P. Pavlenko, I.O. Kozachko
{"title":"Promising directions for the development of means that can increase the adaptation capabilities of the human body under the conditions of the negative influence of the life environment","authors":"A. Kalashnikov, N. Kurdil, O.O. Khudaykulova, O.S. Zulfiharov, H. Petrashenko, V. P. Atamaniuk, P. Zhminko, A. Hrynko, A. O. Zulfiharov, I. P. Pavlenko, I.O. Kozachko","doi":"10.33273/2663-9726-2022-57-2-41-62","DOIUrl":"https://doi.org/10.33273/2663-9726-2022-57-2-41-62","url":null,"abstract":"Abstract. The ever-increasing anthropogenic chemical load throughout the world prompts the search for sources of biologically active substances (BAS) capable of increasing the adaptive capabilities of a person exposed to the harmful effects of the environment.\u0000\u0000Aim. Scientific substantiation of the optimal composition of recipes and features of the production technology of products with immunomodulating and adaptogenic effects (dietary supplements, detoxification products for external use, including cosmetic preventive products for hand skin disinfection), based on technologically processed vegetable waste used in the production of pharmaceutical products Proteflazidum®\".\u0000\u0000Material and Methods. The chemical composition of the ethanol extract of the plant raw material \"Proteflazidum®\" and the waste of its production - meal was studied. The mass fraction of flavonoid compounds aglycones of tricin, apigenin, luteolin, amino acids, sugars, carboxylic acids, natural polymers (pectin substances, chlorophylls and hemicellulose), ethanol (%, vol) was determined. The methods of ultra-high-performance high-speed liquid chromatography with diode-matrix detection (UPLCPDA, Waters, USA) were used; method of ultra-high-performance mass spectrometric high-speed liquid chromatography with electron spray ionization (UPLC-MC/MC, Waters, USA). A study of the dietary supplements \"Immunoflazid Light\" (syrup) and \"Immunoflazid Pro\" (capsules), manufactured in accordance with TU U 10.8-25589583-001:2020, was conducted according to safety indicators: the content of heavy metals, pesticides and radionuclides for compliance with the requirements of GN 4.4.8.073 -2001 \"Temporary hygienic standards for the content of chemical and biological contaminants in biologically active supplements\", approved by the resolution of the chief state sanitary doctor of Ukraine dated 04.20.2001. No. 131 and GN 6.6.1.1-130-2006 \"Permissible levels of the content of radionuclides 137Cs, 90Sr in food and drinking water\", approved by the order of the Ministry of Health of Ukraine dated 05.03.2006 under No. 256. A spectrometer was used to determine the content of lead, cadmium, and mercury atomic emission \"SHIMADSU ICPE - 9820\"; for the determination of radionuclides, the spectrometer \"SEG-001\", \"AKP-S\" and the spectrometer \"SEB-01-70\" were used. Methods of measuring pesticides according to DSTU EN 12393-1:2003, DSTU EN 12393-2:2003, DSTU EN 12393-3:2003 and GOST 30349-96.\u0000\u0000Results. The waste of vegetable raw materials, which is formed as a result of the production of the \"Proteflazidum®\", is a valuable source of BAS, which allows you to consider them as raw materials for creating recipes of products with an adaptogenic effect - dietary supplements and raw materials for the production of products for external use, including cosmetic prophylactic and means for hand skin disinfection. According to safety indicators, the new products belong to low-hazard substances when applied to the skin (hazard ","PeriodicalId":231282,"journal":{"name":"One Health and Nutrition Problems of Ukraine","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125775050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative analysis of the clinical course of narcotic poisoning with different combinations of opioids, psychostimulants and alcohol 阿片类药物、精神兴奋剂和酒精不同组合麻醉中毒临床过程的比较分析
One Health and Nutrition Problems of Ukraine Pub Date : 2022-11-11 DOI: 10.33273/2663-9726-2022-56-1-50-61
N. Kurdil, O. V. Ivashchenko, V. Andriuschenko, K.O. Suprun
{"title":"Comparative analysis of the clinical course of narcotic poisoning with different combinations of opioids, psychostimulants and alcohol","authors":"N. Kurdil, O. V. Ivashchenko, V. Andriuschenko, K.O. Suprun","doi":"10.33273/2663-9726-2022-56-1-50-61","DOIUrl":"https://doi.org/10.33273/2663-9726-2022-56-1-50-61","url":null,"abstract":"Abstract. Clinical evaluation of combined drug poisoning is a rather difficult matter, since despite the progress in understanding the pharmacological effects and toxicity of many modern narcotic substances and precursors, their combined action in most cases remains unknown.\u0000\u0000Aim: to study the features of the clinical course of combined poisoning caused by the simultaneous consumption of drugs of different groups and alcohol.\u0000\u0000Materials and Methods. The medical data of 212 cases of drug poisoning (overdose) were studied. Clinical and laboratory parameters of patients with various combinations of opioids, alcohol and psychostimulants were evaluated. Statistical analysis was carried out using the Microsoft Excel 2019, Student's t-test for paired samples, Pearson's correlation analysis, p≤0.05 was used.\u0000\u0000Results. The use of opioids, alcohol, and psychostimulants in various combinations leads to the development of a specific picture of poisoning. Depending on the combination of narcotic substances and alcohol, these or other toxic symptoms and syndromes occur, which differ in nature, duration, intensity, and frequency depending on the combination and dose of narcotic substances. Combined poisoning with the participation of opioids, alcohol, and psychostimulants differ in the frequency of hypotension, arrhythmias, muscle atony, rhabdomyolysis, electrolyte and metabolic disorders. There was a correlation established between the number of toxicants and the duration of the patient's stay in the intensive care unit (r=0.7864, p=0.00123) and the presence of biomarkers of nephro- and hepatotoxicity (r=0.5285, p =0.00411); the correlation between the number of toxicants and the development of oligo-anuria was not confirmed (r=0.0007, p=0.001).\u0000\u0000Conclusions. The study of the clinical and laboratory features of the course of combined drug poisoning caused by the simultaneous consumption of 3 or more toxicants is an urgent direction of modern clinical toxicology and emergency medicine.\u0000\u0000Key Words: drugs, alcohol, combined poisonings.","PeriodicalId":231282,"journal":{"name":"One Health and Nutrition Problems of Ukraine","volume":"226 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116849550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The topicality of the issue of nitrates control in food products 食品中硝酸盐控制问题的时效性
One Health and Nutrition Problems of Ukraine Pub Date : 2022-11-11 DOI: 10.33273/2663-9726-2022-56-1-19-34
H.А. Demich, A.V. Koval, N. Stadnichuk, T. V. Yevtushenko, T.P. Kostiuchenko
{"title":"The topicality of the issue of nitrates control in food products","authors":"H.А. Demich, A.V. Koval, N. Stadnichuk, T. V. Yevtushenko, T.P. Kostiuchenko","doi":"10.33273/2663-9726-2022-56-1-19-34","DOIUrl":"https://doi.org/10.33273/2663-9726-2022-56-1-19-34","url":null,"abstract":"Abstract. Nitrates are natural metabolic products of all plants. They are vital to plants – without them their normal growth and development is impossible. However, the uncontrolled use of nitrogen fertilizers has led to their uncontrolled accumulation in food products. When eating vegetables with high amounts of nitrates, they are partially restored to nitrites in the intestinal tract, and the latter, entering the bloodstream cause diseases – methemoglobinemia. Therefore, quantitative and qualitative determination of nitrates and nitrites in plant and animal products, water and soils are relevant today. Based on the analysis of scientific literature, the essence of the problem of excessive accumulation of nitrates in agricultural products and their negative impact on human health is highlighted.\u0000\u0000Aim. The aim of the research was to determine experimentally the concentration of nitrates and nitrites in plant and animal products, water and soils, to compare it with the maximum allowable concentration as required by Commission Regulation (EU) No 1258/2011 on maximum nitrate content in vegetables and by State sanitary rules and regulations on Maximum Permissible Levels of Certain Contaminants in Food, approved by the Order of the Ministry of Health of Ukraine of May 13, 2013 No 368 (as amended by the order of the Ministry of Health of Ukraine of May 22, 2020 No 1238).\u0000\u0000Materials and Methods. Sources of information retrieval in printed and electronic publications, databases search engines, methods of analysis, comparison and generalization of data. Photometric method.\u0000\u0000Results. The analysis of the value of nitrates in nature, sources of this substance in food was conducted; normalization of the content of nitrate components, the problem of plant products quality decline due to the uncontrolled use of fertilizers was studied; the content of nitrates in plant and animal products; the harmful effects of products with high nitrate content were considered; a comprehensive assessment of nitrate content in plant products was carried out; comparative characteristics of methods for determination of nitrate compounds were given; the consequences of consumption of products with high nitrate content were analyzed.\u0000\u0000Conclusions. The problem of nitrate pollution is becoming increasingly significant, because the amount and speed of the nitrate nitrogen cycle in the environment is constantly increasing, which increases its impact on natural systems and the possibility of nitrate accumulation in crop products, humans and animals. Therefore, the implementation of analytical control of food and environmental objects is important to obtain objective information about the content of man-made pollutants, which are nitrates and nitrites.\u0000\u0000Key Words: nitrates, maximum permissible level, nitrate compounds, nitrate pollution.","PeriodicalId":231282,"journal":{"name":"One Health and Nutrition Problems of Ukraine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129147669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peculiarities of protein exchange, protein physiological significance and its actual content in the diets of children living on the territories radioactively contaminated as a result of the Chernobyl accident 由于切尔诺贝利事故而受到放射性污染的领土上生活的儿童的蛋白质交换特点、蛋白质生理意义及其在饮食中的实际含量
One Health and Nutrition Problems of Ukraine Pub Date : 2022-11-11 DOI: 10.33273/2663-9726-2022-56-1-35-49
I. Matasar
{"title":"Peculiarities of protein exchange, protein physiological significance and its actual content in the diets of children living on the territories radioactively contaminated as a result of the Chernobyl accident","authors":"I. Matasar","doi":"10.33273/2663-9726-2022-56-1-35-49","DOIUrl":"https://doi.org/10.33273/2663-9726-2022-56-1-35-49","url":null,"abstract":"Abstract. Aim. Proteins as well as other food ingredients form tissues, they are involved in the growth, development and recovery of organs and systems of living organisms, are a component of enzymes and hormones.\u0000\u0000Materials and Methods. The main sources of proteins for the human body and their functional significance are presented in the article. The focus is on the actual consumption of protein by children living in settlements affected by the Chernobyl accident. It is shown that children’s diets did not contain enough meat and meat products, fish and fish products, eggs, milk and dairy products, butter, sour cream and hard cheeses. The definition of an ideal protein is given. It is shown that the quality of proteins is determined by the set of amino acids of which they consist and their total number, as well as the sequence of connection of the latter with each other.\u0000\u0000Conclusions. The content of essential amino acids according to children’s diets is analyzed and their significance is described. The need to take measures to ensure protein intake within physiological needs, which will contribute to the prevention of nutritional deficiency and nutritional deficiency related diseases, was emphasized.\u0000\u0000Key Words: Chernobyl accident, infantile atrophy, hypothalamus, sources of receipt, ideal protein, kwashiorkor, population, indispensable amino acids, oligopeptides, nutrients, recommended daily intake, polypeptides, food, receptor imprinting, protein consumption, physiological significance, center of hunger.","PeriodicalId":231282,"journal":{"name":"One Health and Nutrition Problems of Ukraine","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129040986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On the results of international cooperation of the research center in the field of chemical, biological, radiologycal and nuclear safety (2017-2021) 化学、生物、放射和核安全领域研究中心国际合作成果(2017-2021年)
One Health and Nutrition Problems of Ukraine Pub Date : 2022-11-11 DOI: 10.33273/2663-9726-2022-56-1-62-73
M. Prodanchuk, O. Kravchuk, N. Kurdil, L. A. Ustinova, A. Hrynko, P.V. Aleynov, V. Mykhailov
{"title":"On the results of international cooperation of the research center in the field of chemical, biological, radiologycal and nuclear safety (2017-2021)","authors":"M. Prodanchuk, O. Kravchuk, N. Kurdil, L. A. Ustinova, A. Hrynko, P.V. Aleynov, V. Mykhailov","doi":"10.33273/2663-9726-2022-56-1-62-73","DOIUrl":"https://doi.org/10.33273/2663-9726-2022-56-1-62-73","url":null,"abstract":"Abstract. The scale and nature of the existing external and internal threats form the directions of international security cooperation for Ukraine, which today focus on a range of topical issues in the field of chemical, biological and radiation safety.\u0000\u0000Aim. Evaluation of the results of international cooperation of the Scientific Center in the field of chemical safety, in particular in matters related to the identification of controlled and toxic chemical substances.\u0000\u0000Materials and Methods. The results of the international activity of the Scientific Center in the field of chemical safety for the past 5 years are summarized; cooperation with international donors, representatives of the government of Ukraine, scientists and non-governmental organizations is summarized.\u0000\u0000Results. A key event in the field of international cooperation was participation in G-7 Regular Meeting within the framework of the Global Partnership (Munich, Germany, 2014), where Ukraine presented about 90 projects in three areas: chemical, biological and physical nuclear safety. The results of the implementation of OSCE Project Coordinator in Ukraine: \"Integrated Chemical Safety and Security Program in Ukraine (ICSSP) (2014-2019) and \"Enhancing Ukraine's Chemical Emergency Response Capacity) (2020-2021) are highly appreciated. Participation in Project Project 57: Strengthening crime scene forensics capabilities in investigating CBRN incidents in the South East and Eastern Europe Centers of Excellence Region (2018-2020) and \"South East and Eastern Europe CBRN Risk Mitigation and Security Governance Program (UNICRI) (2021) had significant scientific and practical results.\u0000\u0000Conclusions. Participation in the work of international projects is invaluable in shaping the professional worldview of scientists and specialists whose activities belong to the sphere of CBRN security. The joint implementation of international initiatives provides a real opportunity for the operational implementation of new experience in practice, which is reflected in the plans of scientific works, the content of trainings and educational programs for the training of specialists who, according to their professional duties, need modern knowledge in the field of managing the consequences of CBRN threats.\u0000\u0000Key Words: chemicals, chemical safety, toxicology.","PeriodicalId":231282,"journal":{"name":"One Health and Nutrition Problems of Ukraine","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125419518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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