Thrombosis research最新文献

{"title":"Validation of a Simplified Diagnostic Algorithm for Deep Vein Thrombosis","authors":"Sasha Sharma , Linnea Soon , Kerstin de Wit , Alejandro Lazo-Langner , Grégoire Le Gal , Shannon Bates , Sameer Parpia","doi":"10.1016/j.thromres.2024.109165","DOIUrl":"10.1016/j.thromres.2024.109165","url":null,"abstract":"","PeriodicalId":23064,"journal":{"name":"Thrombosis research","volume":"242 ","pages":"Article 109165"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Predictive Model to Identify Pulmonary Embolism in Unselected Emergency Department Patients: Model Validation and Improvement During the COVID Era","authors":"Dennis Christopher , Keerat Grewal , Dorsa Ghahramani , Soheila Nadalia , Kerstin de Wit","doi":"10.1016/j.thromres.2024.109157","DOIUrl":"10.1016/j.thromres.2024.109157","url":null,"abstract":"","PeriodicalId":23064,"journal":{"name":"Thrombosis research","volume":"242 ","pages":"Article 109157"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anticoagulant Management of Cancer-Associated Thrombosis and Thrombocytopenia: A Retrospective","authors":"Robin MacKenzie , Umaima Abbas , Ushra Khan , Rija Fatima , Tzu-Fei Wang , Rong Luo , Caroline Hamm , Andrea Cervi","doi":"10.1016/j.thromres.2024.109164","DOIUrl":"10.1016/j.thromres.2024.109164","url":null,"abstract":"","PeriodicalId":23064,"journal":{"name":"Thrombosis research","volume":"242 ","pages":"Article 109164"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Risk of Bleeding in Pregnant Women with Acute Venous Thromboembolism Treated with Anticoagulants: An International Multi-Database Cohort Study","authors":"Camille Simard , Isabelle Malhamé , Christopher Filliter , Annika Vivirito , Kristian B. Filion , Haim Abenhaim , Dirk Enders , Antonios Douros , Vicky Tagalakis","doi":"10.1016/j.thromres.2024.109167","DOIUrl":"10.1016/j.thromres.2024.109167","url":null,"abstract":"","PeriodicalId":23064,"journal":{"name":"Thrombosis research","volume":"242 ","pages":"Article 109167"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142525761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of an ADAMTS13-based Therapy for Thrombosis","authors":"Rex Haung , Veronica DeYoung , Hasam Madarati , Colin Kretz","doi":"10.1016/j.thromres.2024.109159","DOIUrl":"10.1016/j.thromres.2024.109159","url":null,"abstract":"","PeriodicalId":23064,"journal":{"name":"Thrombosis research","volume":"242 ","pages":"Article 109159"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scoping review of current evidence on the incidence of Venous thromboembolism (VTE) in the East Asian population","authors":"Firas Q.J. Jumaili","doi":"10.1016/j.thromres.2024.109161","DOIUrl":"10.1016/j.thromres.2024.109161","url":null,"abstract":"","PeriodicalId":23064,"journal":{"name":"Thrombosis research","volume":"242 ","pages":"Article 109161"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Optimal Time of Administration of Heparin that will Improve Survival in a Murine Model of Sepsis","authors":"Zarafshan Khan , Dhruva J. Dwivedi , Erblin Cani , Angela Bilic , Alessandra Giglia , Brenda Lin , Harman Bhogal , Maggie Chan , Seline May , Tyler Carson , Patricia C. Liaw","doi":"10.1016/j.thromres.2024.109162","DOIUrl":"10.1016/j.thromres.2024.109162","url":null,"abstract":"","PeriodicalId":23064,"journal":{"name":"Thrombosis research","volume":"242 ","pages":"Article 109162"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of anticoagulation on the long-term survival of patients with pulmonary arterial hypertension: A meta-analysis of 15 cohort studies","authors":"Xinwang Chen ,&nbsp;Zhenguo Zhai ,&nbsp;Lan Lin ,&nbsp;Dan Xue ,&nbsp;Xiangqi Chen ,&nbsp;Hong Zhang ,&nbsp;Qiong Lin","doi":"10.1016/j.thromres.2024.109173","DOIUrl":"10.1016/j.thromres.2024.109173","url":null,"abstract":"<div><h3>Introduction</h3><div>Anticoagulation was once recommended for patients with pulmonary arterial hypertension (PAH). However, its survival benefit still remained controversial. We performed a meta-analysis to evaluate the effect of anticoagulation on the long-term survival of PAH patients.</div></div><div><h3>Methods</h3><div>The PubMed, EMBASE, Web of Science, and WanFang electronic database were searched for eligible studies. Pooled hazard ratios (HRs) with 95 % confidence intervals (CIs) were calculated for effect estimate regarding anticoagulation on the survival of PAH patients.</div></div><div><h3>Results</h3><div>Fifteen cohort studies involving 4266 PAH patients were included. Approximately 45.8 % patients received anticoagulation. The mean follow-up period ranged from 2.1 to 14 years. Anticoagulation had a tendency to, however, did not significantly reduce mortality of PAH patients (HR: 0.86, 95 % CI: 0.73–1.02). In subgroup analysis, anticoagulation decreased the mortality risk as analyzed from retrospective studies (HR: 0.80, 95 % CI: 0.65–0.98), but not prospective studies (HR: 0.95, 95 % CI: 0.70–1.29). For both idiopathic PAH (IPAH) and connective tissue disease associated PAH (CTD-PAH), anticoagulation therapy did not significantly improve the long-term survival rate (HR: 0.83, 95 % CI: 0.65–1.07, and HR: 1.05, 95 % CI: 0.77–1.42, respectively), and this result remained unchanged when pooling data from either retrospective or prospective studies. Further analysis showed that anticoagulation had no advantage in reducing mortality in patients with systemic sclerosis associated PAH, systemic erythematosus lupus related PAH (free of antiphospholipid syndrome), or CTD-PAH of non-specified etiology.</div></div><div><h3>Conclusion</h3><div>Anticoagulation may not reduce the long-term mortality of PAH patients, including those with IPAH and CTD-PAH. In the management of PAH, anticoagulants should be prescribed with caution before comprehensive risk to benefit evaluation. Larger and more vigorously designed controlled trials are warranted.</div></div>","PeriodicalId":23064,"journal":{"name":"Thrombosis research","volume":"243 ","pages":"Article 109173"},"PeriodicalIF":3.7,"publicationDate":"2024-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142376082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neutralizing protease Nexin-1 in hemophilia patients on emicizumab improves thrombin generation","authors":"Véronique Arocas ,&nbsp;Laurence Venisse ,&nbsp;Yacine Boulaftali ,&nbsp;Stéphane Loyau ,&nbsp;Claire Flaujac ,&nbsp;Emmanuelle de Raucourt ,&nbsp;Marie-Christine Bouton","doi":"10.1016/j.thromres.2024.109174","DOIUrl":"10.1016/j.thromres.2024.109174","url":null,"abstract":"","PeriodicalId":23064,"journal":{"name":"Thrombosis research","volume":"243 ","pages":"Article 109174"},"PeriodicalIF":3.7,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142393613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemophilia A: Economic burden, therapeutic advances, and future forecasts in the Middle East and North Africa region","authors":"Radwa Ahmed Batran ,&nbsp;Mohab Kamel ,&nbsp;Ayman Bahr ,&nbsp;Ahmed Khalil ,&nbsp;Mohamed Elsokary","doi":"10.1016/j.thromres.2024.109175","DOIUrl":"10.1016/j.thromres.2024.109175","url":null,"abstract":"<div><div>Hemophilia A, a severe hereditary hemorrhagic disorder characterized by a deficiency in blood clotting factors, imposes a significant economic burden on individuals, healthcare systems, and society, with inhibitors exacerbating the socioeconomic impact. The detrimental impact on the quality of life for patients and caregivers, including functional limitations, is particularly pronounced during bleeding episodes and in the presence of inhibitors. The increasing prevalence of Hemophilia A across the MENA region is evident, marked by the approval of various therapies and intensified research and development efforts focusing on treatment innovations. Despite commendable progress in Hemophilia management, challenges persist in providing care for Hemophilia patients in the region. This review aims to shed light on the current landscape, challenges, and market forecasts for Hemophilia A in the MENA region. Additionally, it strives to provide valuable insights for the future, emphasizing the need for clear approaches to ensure comprehensive care for individuals with Hemophilia.</div></div>","PeriodicalId":23064,"journal":{"name":"Thrombosis research","volume":"243 ","pages":"Article 109175"},"PeriodicalIF":3.7,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142372944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}