The Korean Journal of Helicobacter and Upper Gastrointestinal Research最新文献_第7页

[Management of Type 1 Gastric Neuroendocrine Tumors Less than 10 mm in Diameter]. 直径小于10mm的1型胃神经内分泌肿瘤的治疗

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-03-01 Epub Date: 2023-03-09 DOI: 10.7704/kjhugr.2022.0065

Jae Kyu Sung

引用次数: 0

Homogenous Subepithelial Esophageal Lesion. 同质性食管上皮下病变

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-03-01 Epub Date: 2023-03-09 DOI: 10.7704/kjhugr.2023.0004

Jin Ook Jang, Su Jin Kim, Cheol Woong Choi

引用次数: 0

Probiotic Supplementation for Treatment of Helicobacter pylori Infection: A Double-Blind Randomized Clinical Trial. 益生菌补充剂治疗幽门螺杆菌感染的双盲随机临床试验

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-03-01 Epub Date: 2023-02-27 DOI: 10.7704/kjhugr.2022.0051

Na Rae Lim, Soo Yeon Choi, Woo Chul Chung

{"title":"Probiotic Supplementation for Treatment of Helicobacter pylori Infection: A Double-Blind Randomized Clinical Trial.","authors":"Na Rae Lim, Soo Yeon Choi, Woo Chul Chung","doi":"10.7704/kjhugr.2022.0051","DOIUrl":"10.7704/kjhugr.2022.0051","url":null,"abstract":"Background/aims: The effects of probiotic supplementation on Helicobacter pylori (H. pylori) eradication therapy are not completely understood. In this study, we investigated the effects of continuous probiotic administration on eradication rates, recrudescence, and symptom response following completion of a course of H. pylori therapy.Methods: This prospective, randomized, double-blind placebo-controlled trial was performed between June 2018 and 2020. Twohundred seventy patients who received a standard triple regimen for H. pylori eradication, were included in the study. Participants were randomized to receive a probiotic as adjunctive therapy (Enterococcus faecium 4.5×108 and Bacillus subtilis 5.0×107; Medilac-S®, Hanmi Pharmaceuticals, Seoul, Korea) or a placebo (one tablet thrice daily) for 28 days, following H. pylori eradication. Participants who showed successful eradication underwent a repeat 13C-urea breath test after 6 months.Results: Eradication rates in the probiotic and placebo groups were 77.1% and 72.4%, respectively (P=0.48) using per-protocol analysis. Using intention-to-treat analysis, eradication rates were 67.4% and 65.9%, respectively (P=0.43). Of 149 patients who were followed-up after 6 months, four patients had recrudescence (2.7%). Recrudescence rates did not differ between the probiotic and placebo groups. Of the 76 patients who had non-ulcer dyspepsia, 60 (78.9%) showed symptom resolution after 6 months. This beneficial effect was most pronounced in patients with postprandial distress syndrome (P=0.02).Conclusions: Consecutive probiotic supplementation following H. pylori eradication therapy did not increase eradication rates or decrease recrudescence rates.","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":" ","pages":"34-41"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44259628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Approach to Small Gastric Subepithelial Lesions]. 胃上皮下小病变的入路

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-03-01 Epub Date: 2023-03-09 DOI: 10.7704/kjhugr.2023.0020

Moon Won Lee, Bong Eun Lee

引用次数: 0

[Approach to Patients after Successful Eradication of Helicobacter pylori]. 幽门螺杆菌成功根除后患者的处理方法

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-03-01 Epub Date: 2023-03-09 DOI: 10.7704/kjhugr.2023.0019

Hee Seok Moon

引用次数: 0

[Approach to Patients with Consecutive Helicobacter pylori Eradication Failure]. 幽门螺杆菌连续根除失败患者的治疗方法

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-03-01 Epub Date: 2023-03-09 DOI: 10.7704/kjhugr.2023.0017

Sung Eun Kim

{"title":"[Approach to Patients with Consecutive Helicobacter pylori Eradication Failure].","authors":"Sung Eun Kim","doi":"10.7704/kjhugr.2023.0017","DOIUrl":"10.7704/kjhugr.2023.0017","url":null,"abstract":"Helicobacter pylori (H. pylori) is associated with various gastrointestinal disorders, such as gastritis, peptic ulcers, mucosa-associated lymphoid tissue lymphoma, and gastric cancer. Therefore, the International Agency for Research on Cancer, a specialized cancer agency of the World Health Organization, categorizes H. pylori as a definite gastric carcinogen (group I). H. pylori eradication is a major challenge both medically and socioeconomically in countries with high prevalence of H. pylori and gastric cancer. However, the efficacy of first-line clarithromycin-containing triple therapy and second-line bismuth-containing quadruple therapy continues to decline worldwide including in Korea. The role of salvage therapy is being recognized globally; however, the exact salvage therapy which is useful in daily clinical practice remains unestablished. In this review, factors associated with eradication failure will be discussed. Furthermore, eradication regimens that may be useful as salvage therapies based on Korean guidelines, Maastricht VI/Florence consensus report and previous research are summarized.","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":" ","pages":"15-21"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42226691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prediction of Severity and Adverse Outcomes Associated with Perforation in Patients Presenting to the Emergency Department with Esophageal Injury. 预测急诊科食管损伤患者穿孔的严重程度和不良结局

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-03-01 Epub Date: 2023-02-01 DOI: 10.7704/kjhugr.2022.0057

Eui Sun Jeong, Hye-Kyung Jung, Ju Ran Byeon, Ayoung Lee, Ji Taek Hong, Seong-Eun Kim, Chang Mo Moon

{"title":"Prediction of Severity and Adverse Outcomes Associated with Perforation in Patients Presenting to the Emergency Department with Esophageal Injury.","authors":"Eui Sun Jeong, Hye-Kyung Jung, Ju Ran Byeon, Ayoung Lee, Ji Taek Hong, Seong-Eun Kim, Chang Mo Moon","doi":"10.7704/kjhugr.2022.0057","DOIUrl":"10.7704/kjhugr.2022.0057","url":null,"abstract":"Background/aims: Esophageal perforation is associated with high mortality and morbidity in patients presenting to the emergency department (ED) with esophageal injury. We investigated the effectiveness of initial CT scan in patients with esophageal injury to determine the risk factors for complications.Methods: Patients admitted through the ED for evaluation of esophageal injuries between January 2001 and May 2020, were investigated. Demographic data, etiological factors, comorbidities, treatment administered, and outcomes were collected. Esophageal injury was graded based on the following CT criteria: (a) normal, (b) pneumomediastinum, (c) mediastinitis, fluid collection, abscess, or overt esophageal wall injury, and (d) pleural effusion, subcutaneous emphysema, or pneumothorax. Grade 2 was defined as microperforation and grades 3 and 4 as overt perforation.Results: Of 281 patients with esophageal injury, 38 had CT-documented overt perforations and 20 had microperforations. Foreign body-induced injury (n=37), Boerhaave syndrome (n=12), and chemical injury (n=3) were common causes of esophageal injury. Complications occurred in 24 (8.5%) patients. Risk factors for complications were age ≥65 years (OR 4.14, 95% CI 1.18~14.56, P=0.027), cerebrovascular disease (OR 8.58, 95% CI 1.13~65.19, P=0.038), Boerhaave syndrome (OR 12.52, 95% CI 2.07~75.68, P=0.006), chemical injury (OR 15.72, 95% CI 3.67~67.28, P<0.001), and CT-documented grade 4 perforation (OR 15.75, 95% CI 4.39~56.55, P<0.001).Conclusions: Initial CT-based grading in the ED are useful for predicting potential complications and for managing patients with esophageal injury and suspected perforation.","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":" ","pages":"42-51"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46193226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Is Probiotic Supplementation Useful for Helicobacter pylori Eradication?] 益生菌补充剂对根除幽门螺杆菌有用吗？

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-03-01 Epub Date: 2023-03-09 DOI: 10.7704/kjhugr.2023.0007

Ki-Nam Shim

引用次数: 0

[Gastric Inverted Hyperplastic Polyp Removed Using Endoscopic Submucosal Dissection]. 胃内翻性增生性息肉内镜下粘膜剥离术

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-03-01 Epub Date: 2023-02-27 DOI: 10.7704/kjhugr.2022.0059

Jee Won Boo, Joon Sung Kim, Byung-Wook Kim

{"title":"[Gastric Inverted Hyperplastic Polyp Removed Using Endoscopic Submucosal Dissection].","authors":"Jee Won Boo, Joon Sung Kim, Byung-Wook Kim","doi":"10.7704/kjhugr.2022.0059","DOIUrl":"10.7704/kjhugr.2022.0059","url":null,"abstract":"Gastric subepithelial tumors (SETs) are usually asymptomatic and are often detected incidentally during screening endoscopy. A gastric inverted hyperplastic polyp (IHP) is characterized by downward growth of hyperplastic mucosa into the submucosal layer. Owing to these characteristics, a gastric IHP is frequently misdiagnosed as a SET. Gastric IHPs are asymptomatic in most cases and are discovered incidentally. Notably, IHPs may be accompanied by an adenocarcinoma or anemia owing to chronic bleeding associated with this lesion; therefore, endoscopic submucosal dissection is recommended for complete excision of IHPs measuring > 2 cm. We report a case of gastric IHP that was diagnosed during screening endoscopy in an asymptomatic patient. We observed a whitish purulent exudate expressed from the SET, and endoscopic ultrasonography revealed a SET originating from the muscularis mucosa. Endoscopic submucosal dissection was performed to remove the SET, and final histopathological findings revealed a gastric IHP. This case report highlights that IHPs should be suspected in patients with a SET associated with whitish exudates.","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":" ","pages":"63-67"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43753419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Clinical Efficacy of Transcatheter Arterial Embolization for Acute Non-Variceal Gastrointestinal Bleeding]. 经导管动脉栓塞治疗急性非静脉曲张性胃肠道出血的临床疗效

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-03-01 Epub Date: 2023-03-09 DOI: 10.7704/kjhugr.2023.0002

Won Shik Kim, Moon Kyung Joo

引用次数: 0