{"title":"The Dual Role of Media in Addiction: Shaping Narratives, Reinforcing Stigma, and Influencing Policy Outcomes.","authors":"Ellie Nadelmann","doi":"10.4088/PCC.25br04119","DOIUrl":"10.4088/PCC.25br04119","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148438036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melissa P Bui, Elisabeth A Dietrich, Michalla B Braford, Katerina Mastronardi, Theodore A Stern
{"title":"Communicating With Intubated Patients: Challenges Faced by Health Care Providers, Patients, and Family Members.","authors":"Melissa P Bui, Elisabeth A Dietrich, Michalla B Braford, Katerina Mastronardi, Theodore A Stern","doi":"10.4088/PCC.25f04104","DOIUrl":"https://doi.org/10.4088/PCC.25f04104","url":null,"abstract":"<p><p>The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. These discussions have given rise to rounds reports that will prove useful for clinicians practicing at the interface of medicine and psychiatry.</p><p><p><i>Prim Care Companion CNS Disord</i> <i>2026;28(4):25f04104</i>.</p><p><p>\u0000 <i>Author affiliations are listed at the end of this article.</i>\u0000 </p>","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148376980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rajat Rawat, Pravesh Thapliyal, Raunak Kumar, Yogesh Joshi, Shobit Garg
{"title":"Beyond Pharmacology: Do Tablet Shape, Size, and Color Influence Medication Adherence in Psychiatric Outpatients?","authors":"Rajat Rawat, Pravesh Thapliyal, Raunak Kumar, Yogesh Joshi, Shobit Garg","doi":"10.4088/PCC.25m04101","DOIUrl":"10.4088/PCC.25m04101","url":null,"abstract":"<p><p><b>Background:</b> Medication nonadherence is a multifaceted challenge in psychiatric treatment, driven by clinical, psychosocial, and patient factors. An understudied aspect is the physical properties of solid oral dosage forms (SODFs)-shape, size, and color-which may influence acceptability and adherence. Yet, quantitative evidence connecting real-world preferences to adherence outcomes is scarce, especially in psychiatric settings.</p><p><p><b>Objective:</b> To evaluate preferences for tablet shape, size, and color among psychiatric outpatients and their relation to self-reported adherence.</p><p><p><b>Methods:</b> This cross-sectional observational study, conducted over 6 months (April-October 2024) in a tertiary psychiatric unit, included 232 patients with varied psychiatric diagnoses on oral medications. Sociodemographics, clinical details, and preferences/dislikes for tablet attributes (shape: flat circular vs oval/oblong; size: small, medium, large; color: white, yellow, red, blue) were gathered via a structured questionnaire. Adherence was measured using the validated 10-item Medication Adherence Rating Scale (score ≥6=adherent). Associations were analyzed with χ<sup>2</sup> and Fisher exact tests (<i>P</i><.05).</p><p><p><b>Results:</b> The cohort (mean age: 36±13.3 years; 65.1% male) had 74.1% adherence (95% CI, 68.1-79.3%). Preferences included oval/oblong shapes (43.5%), small sizes (41.4%), and white colors (41.8%); dislikes were large sizes (53.4%), flat-circular shapes (40.5%), and red colors (33.6%). No significant links existed between preferences/dislikes and adherence (all <i>P</i> >.05; χ<sup>2</sup> = 1.90-4.64; Cramér's V=0.09-0.14). Adherence rates varied by diagnosis (lowest in psychosis: 30.8%; 95% CI, 12.7-57.6% and highest in generalized anxiety disorder: 85.0%; 95% CI, 64.0-94.8%) but nonsignificantly (χ<sup>2</sup> =16.70, <i>P</i>= .081, Cramér's V=0.27).</p><p><p><b>Conclusion:</b> Psychiatric patients show distinct esthetic preferences for tablets, consistent with prior acceptability research, but these do not predict adherence. Clinical symptoms, illness insight, and therapeutic alliance appear to dominate. Strategies should emphasize psychosocial interventions rather than formulation esthetics.</p><p><p><i>Prim Care Companion CNS Disord</i> <i>2026;28(4):25m04101</i>.</p><p><p>\u0000 <i>Author affiliations are listed at the end of this article.</i>\u0000 </p>","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148376396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shushank Tej Tekupalli, Anirudh Bakam, Sai Spoorthy Mamidipalli, Sai Krishna Tikka
{"title":"Fluoxetine-Induced Liver Injury in a Patient With Post-Schizophrenic Depression.","authors":"Shushank Tej Tekupalli, Anirudh Bakam, Sai Spoorthy Mamidipalli, Sai Krishna Tikka","doi":"10.4088/PCC.26cr04182","DOIUrl":"https://doi.org/10.4088/PCC.26cr04182","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148377021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Franklin King, Juliana Zambrano, Erin Mauney, Kabir Nigam, Fernando Espi Forcen, Brian S Barnett, S Trevor Taylor, Seth A Mattson, Theodore A Stern
{"title":"Psychological Adverse Effects of Psychedelic Use.","authors":"Franklin King, Juliana Zambrano, Erin Mauney, Kabir Nigam, Fernando Espi Forcen, Brian S Barnett, S Trevor Taylor, Seth A Mattson, Theodore A Stern","doi":"10.4088/PCC.25f04172","DOIUrl":"https://doi.org/10.4088/PCC.25f04172","url":null,"abstract":"<p><p>The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. These discussions have given rise to rounds reports that will prove useful for clinicians practicing at the interface of medicine and psychiatry.</p><p><p><i>Prim Care Companion CNS Disord</i> <i>2026;28(3):25f04172</i>.</p><p><p>\u0000 <i>Author affiliations are listed at the end of this article.</i>\u0000 </p>","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148340174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Daily Fantasy Sports as an Emerging Public Health Concern: A Comparative Public Health Perspective of Digital Wagering and Youth Vulnerability.","authors":"Mayank Gupta, Priyal Khurana, Aditya Sharma, Shivam Rangolia, Nihit Gupta","doi":"10.4088/PCC.25nr04142","DOIUrl":"https://doi.org/10.4088/PCC.25nr04142","url":null,"abstract":"<p><p><b>Importance:</b> Daily fantasy sports (DFS) have rapidly become a major component of the global gambling industry, with platforms offering users the opportunity to draft fantasy teams and compete for real monetary rewards based on real-world sports performance. This article compares India's DFS expansion with current US trends, examining regulatory environments, market dynamics, and mental health implications. Emphasis is placed on vulnerable groups, including adolescents, individuals with preexisting psychiatric conditions, and populations with socioeconomic disadvantage. The analysis explores pathways linking DFS engagement to addiction risk and related psychological harms, with attention to contextual cultural factors.</p><p><p><b>Observations:</b> Evidence from India indicates that DFS participation can escalate involvement in additional betting activities and contribute to mental health problems such as compulsive gambling behaviors, anxiety, and stress-related disorders. These patterns offer insights for US policymakers and public health stakeholders as they respond to the rapid growth of online sports wagering. Cross-national differences in cultural attitudes, regulatory enforcement, and media integration are examined to identify strategies with potential for effective adaptation.</p><p><p><b>Conclusions:</b> The findings underscore the need for evidence-based regulatory approaches, targeted public health interventions, and culturally tailored awareness initiatives to mitigate gambling-related harms in both countries. Recommendations are provided to guide policymakers, clinicians, and industry stakeholders in protecting vulnerable populations amid the continued expansion of DFS and online sports betting.</p><p><p><i>Prim Care Companion CNS Disord</i> <i>2026;28(3):25nr04142</i>.</p><p><p>\u0000 <i>Author affiliations are listed at the end of this article.</i>\u0000 </p>","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148340138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Medical and Cultural Approach to Obsessive-Compulsive Disorder.","authors":"Tirth Patel, Shady S Shebak","doi":"10.4088/PCC.25cr04170","DOIUrl":"https://doi.org/10.4088/PCC.25cr04170","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148340149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Franklin King, Brian S Barnett, S Trevor Taylor, Seth A Mattson, Erin Mauney, Juliana Zambrano, Fernando Espi Forcen, Kabir Nigam, Theodore A Stern
{"title":"Medical Complications of Psychedelics.","authors":"Franklin King, Brian S Barnett, S Trevor Taylor, Seth A Mattson, Erin Mauney, Juliana Zambrano, Fernando Espi Forcen, Kabir Nigam, Theodore A Stern","doi":"10.4088/PCC.25f04171","DOIUrl":"https://doi.org/10.4088/PCC.25f04171","url":null,"abstract":"<p><p>The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. These discussions have given rise to rounds reports that will prove useful for clinicians practicing at the interface of medicine and psychiatry.</p><p><p><i>Prim Care Companion CNS Disord</i> <i>2026;28(3):25f04171</i>.</p><p><p>\u0000 <i>Author affiliations are listed at the end of this article.</i>\u0000 </p>","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148340171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New-Onset Visual Snow Syndrome Following Prescription of Bupropion in a Patient With Macular Degeneration and Geographic Atrophy.","authors":"Dax C Volle","doi":"10.4088/PCC.25cr04169","DOIUrl":"https://doi.org/10.4088/PCC.25cr04169","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148278756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Meshberg-Cohen, Shelby R Goodwin, Ian C Fischer, Joan M Cook, Jack Tsai, Robert H Pietrzak
{"title":"Primary Users of the VA Health Care System: Prevalence, Correlates, and Implications for Care Delivery.","authors":"Sarah Meshberg-Cohen, Shelby R Goodwin, Ian C Fischer, Joan M Cook, Jack Tsai, Robert H Pietrzak","doi":"10.4088/PCC.25m04176","DOIUrl":"10.4088/PCC.25m04176","url":null,"abstract":"<p><p><b>Objective:</b> To examine the sociodemographic and clinical profiles of veterans who primarily rely on the US Department of Veterans Affairs (VA) health care system for their care.</p><p><p><b>Methods:</b> Data were analyzed from a nationally representative sample of 4,069 US military veterans who participated in the National Health and Resilience in Veterans Study in 2019-2020.</p><p><p><b>Results:</b> Overall, 20.5% of veterans reported using the VA as their primary source of health care. Compared to non-VA users, these veterans were more likely to be younger, unmarried or unpartnered, and black/African American and to have lower household incomes (≤$60,000 annually). They also reported greater cumulative trauma exposure and were more likely to have a history of depression, posttraumatic stress disorder, and chronic medical conditions such as chronic pain, sleep disorders, and respiratory illnesses.</p><p><p><b>Conclusion:</b> VA health care serves a distinct and vulnerable subgroup of veterans who experience more complex psychiatric and medical needs, as well as greater financial insecurity, compared to non-VA users. These findings underscore the importance of expanding comprehensive, integrated services that address both physical and mental health conditions while accounting for socioeconomic factors to better meet the needs of veterans who rely on VA health care.</p><p><p><i>Prim Care Companion CNS Disord 2026;28(3):25m04176</i>.</p><p><p>\u0000 <i>Author affiliations are listed at the end of this article.</i>\u0000 </p>","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148278816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}