The primary care companion for CNS disorders最新文献

{"title":"Acute Psychosis and Delirium During Menstruation in a Premenopausal Woman With Urinary Tract Infection.","authors":"Sara Ellias, Aateqa Hashmi, Jisselly Sanchez Salcedo, Kayleigh Watson","doi":"10.4088/PCC.26cr04300","DOIUrl":"https://doi.org/10.4088/PCC.26cr04300","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149195994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vintage Find, Modern Emergency: Unexpected Methaqualone Ingestion in an Adolescent.","authors":"Patrick L Tomlinson, Nasuh Malas","doi":"10.4088/PCC.26cr04274","DOIUrl":"https://doi.org/10.4088/PCC.26cr04274","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Electroconvulsive Therapy and Ketamine in a POLG-Related Disorder.","authors":"Sina Hafizi, Vishal Kaushik, Reece Ramkissoon","doi":"10.4088/PCC.26cr04238","DOIUrl":"https://doi.org/10.4088/PCC.26cr04238","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Forty Years of Untreated Anorexia Nervosa: How Bad Can It Get?","authors":"Joana Romão, Marta Rebelo, Patrícia Baronet, Rita André, Tiago Duarte","doi":"10.4088/PCC.26cr04240","DOIUrl":"https://doi.org/10.4088/PCC.26cr04240","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skin and Brain in Bipolar Disorder: A Review of Dermatologic-Psychotropic Drug Interactions.","authors":"Drew Mack, Nina Modanlo, Ingyun Park, Xiaofeng Yan, James Alan Bourgeois","doi":"10.4088/PCC.26nr04252","DOIUrl":"https://doi.org/10.4088/PCC.26nr04252","url":null,"abstract":"<p><p><b>Importance:</b> Dermatologic and psychotropic therapies intersect frequently in patients with bipolar disorder, in whom systemic dermatologic medications may affect mood stability and mood stabilizers or antipsychotics may produce clinically important cutaneous adverse reactions. Because several medications discussed in this review are also used for psychotic disorders, severe or treatment-resistant major depressive disorder, suicidality, and other psychiatric conditions, this article distinguishes medication-related risks from considerations specific to bipolar disorder.</p><p><p><b>Observations:</b> This narrative review synthesized English-language literature indexed in PubMed through June 29, 2026 addressing psychiatric adverse effects of dermatologic therapies and dermatologic adverse effects of psychotropic medications relevant to bipolar disorder. The literature consisted largely of case reports, case series, observational studies, pharmacovigilance analyses, and narrative or systematic reviews. No randomized controlled trials directly evaluating these bidirectional interactions in bipolar disorder were identified. Dermatologic agents such as isotretinoin, systemic corticosteroids, and methotrexate have been associated with mood destabilization in susceptible patients. Conversely, lithium and lamotrigine carry important dermatologic risks, including acneiform or psoriasiform eruptions, hidradenitis suppurativa, and severe cutaneous adverse reactions.</p><p><p><b>Conclusions and Relevance:</b> Dermatologic-psychiatric drug interactions can be clinically significant and require careful screening, counseling, and longitudinal monitoring. Dermatologists, psychiatrists, and primary care clinicians should collaborate when initiating or modifying high-risk therapies, especially when psychiatric history, prior cutaneous drug reactions, polypharmacy, or rapid dose escalation increase risk.</p><p><p><i>Prim Care Companion CNS Disord</i> <i>2026;28(5):26nr04252</i>.</p><p><p>\u0000 <i>Author affiliations are listed at the end of this article.</i>\u0000 </p>","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149138450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Limb Loss After Intentional Dry Ice Frostbite in a Patient With Body Integrity Dysphoria and the Role of Online Identity Communities.","authors":"Ann C Schwartz, Gregg A Robbins-Welty, Caroline Stiles, Nancy Gimbel, Nadine J Kaslow, Laura S Johnson, Bao Chau Ly, Sarah E Dunn","doi":"10.4088/PCC.26cr04277","DOIUrl":"https://doi.org/10.4088/PCC.26cr04277","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149138383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing the Sequelae of Delirium Associated With Critical Illness.","authors":"Joseph D Dragonetti, Maureen K Cassady, Emma R Torncello, Sydney P Williams, Hunter G Shelton, Zachary E Bean, Alejandro E Rodulfo, Dina Soliman, Theodore A Stern","doi":"10.4088/PCC.26f04249","DOIUrl":"https://doi.org/10.4088/PCC.26f04249","url":null,"abstract":"<p><p>The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. These discussions have given rise to rounds reports that will prove useful for clinicians practicing at the interface of medicine and psychiatry.</p><p><p><i>Prim Care Companion CNS Disord</i> <i>2026;28(5):26f04249</i>.</p><p><p>\u0000 <i>Author affiliations are listed at the end of this article.</i>\u0000 </p>","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149138440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Palliative Care and Structured Serious Illness Communication in a Refugee Patient With Amyotrophic Lateral Sclerosis.","authors":"Jillian Rankin, Carina Oltmann, Emily Pinto Taylor, Daniel Schachter, Ashima Lal","doi":"10.4088/PCC.26cr04223","DOIUrl":"https://doi.org/10.4088/PCC.26cr04223","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149138371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When the Therapist's Thoughts Change, the Patient Changes: An Intervention for Adolescent Patients Who Discontinue Psychotherapy Based on a Buddhist Concept.","authors":"Takuji Inagaki","doi":"10.4088/PCC.26cr04227","DOIUrl":"https://doi.org/10.4088/PCC.26cr04227","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence-Associated Psychosis.","authors":"Jamie Harbourd, Suresh Yadav, Kagan Temur, Sandeep Grover","doi":"10.4088/PCC.26cr04260","DOIUrl":"https://doi.org/10.4088/PCC.26cr04260","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"28 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}