{"title":"Mental Health Effects of Tirzepatide: A Report of 2 Patients.","authors":"Marta K Mudd, Jeffrey T Rado","doi":"10.4088/PCC.25cr03931","DOIUrl":"https://doi.org/10.4088/PCC.25cr03931","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144620689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sofia E Matta, Elisabeth Dietrich, Natalie Fedotova, Michalla B Braford, Jonathan deVries, Zachary DiAngelo, Benjamin J Hoover, Theodore A Stern
{"title":"Serious Suicide Attempts: Assessment and Management.","authors":"Sofia E Matta, Elisabeth Dietrich, Natalie Fedotova, Michalla B Braford, Jonathan deVries, Zachary DiAngelo, Benjamin J Hoover, Theodore A Stern","doi":"10.4088/PCC.25f03913","DOIUrl":"https://doi.org/10.4088/PCC.25f03913","url":null,"abstract":"<p><p>The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. These discussions have given rise to rounds reports that will prove useful for clinicians practicing at the interface of medicine and psychiatry.</p><p><p><i>Prim Care Companion CNS Disord</i> <i>2025;27(4):25f03913</i>.</p><p><p>\u0000 <i>Author affiliations are listed at the end of this article.</i>\u0000 </p>","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144620691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Artem F Dadamyan, Hassan Barada, Ibrahim M Sablaban
{"title":"The Hidden Perils of Kratom: A Case of Drug-Induced Psychosis Successfully Treated With a Second-Generation Antipsychotic.","authors":"Artem F Dadamyan, Hassan Barada, Ibrahim M Sablaban","doi":"10.4088/PCC.25cr03935","DOIUrl":"https://doi.org/10.4088/PCC.25cr03935","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144620692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carol Lim, Sarah Maclaurin, Abigail L Donovan, Cheryl Y S, Oliver Freudenreich
{"title":"GLP-1 Receptor Agonists for Clozapine-Induced Weight Gain: A Case Report With the Dual GLP-1/GIP Agonist Tirzepatide.","authors":"Carol Lim, Sarah Maclaurin, Abigail L Donovan, Cheryl Y S, Oliver Freudenreich","doi":"10.4088/PCC.25cr03952","DOIUrl":"https://doi.org/10.4088/PCC.25cr03952","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144620654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Emesis to Amnesia: Wernicke-Korsakoff Syndrome Due to Hyperemesis Gravidarum.","authors":"Ajit Bhalchandra Dahale, Amrita Mandal, Karthik Narasimhappa","doi":"10.4088/PCC.25cr03934","DOIUrl":"https://doi.org/10.4088/PCC.25cr03934","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144620653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ryan Asaukas, Spencer Silvey, Zeenat Habibullah, Chance Friesen, Roopa Sethi
{"title":"Nitrous Oxide and Ketamine Use Producing Ataxia and Neuropathy: A Clinical Case Report.","authors":"Ryan Asaukas, Spencer Silvey, Zeenat Habibullah, Chance Friesen, Roopa Sethi","doi":"10.4088/PCC.24cr03910","DOIUrl":"https://doi.org/10.4088/PCC.24cr03910","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144620690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joyce A Meza Venegas, Gregg A Robbins-Welty, Kristen G Shirey
{"title":"Guillain-Barré Syndrome in a Psychiatric Patient: Diagnostic Pitfalls.","authors":"Joyce A Meza Venegas, Gregg A Robbins-Welty, Kristen G Shirey","doi":"10.4088/PCC.25cr03940","DOIUrl":"https://doi.org/10.4088/PCC.25cr03940","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144620655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joseph Nickel, Sujeeth Shanmugam, Niki Jona, Kaushal Shah, Predrag Gligorovic
{"title":"Readability of English-Language Self-Report Measures in Bipolar Disorder.","authors":"Joseph Nickel, Sujeeth Shanmugam, Niki Jona, Kaushal Shah, Predrag Gligorovic","doi":"10.4088/PCC.24m03892","DOIUrl":"https://doi.org/10.4088/PCC.24m03892","url":null,"abstract":"<p><p><b>Objective:</b> Self-report measures have been used as a tool to evaluate mania and depressive symptoms and aid in diagnosing bipolar disorder. The American Medical Association recommends that the evaluation reading be at a fifth- to sixth-grade level. The research literature has previously established that questionnaires regarding other psychiatric conditions have been written at an elevated reading level compared to the recommended guidelines. The objective of this study was to calculate the overall readability of measures in bipolar disorder and the individual readability of the items and instructions sections.</p><p><p><b>Methods:</b> Measures in assessing bipolar disorder were selected from a publicly available literature search in the PsycINFO, PubMed, PubMed Central, and Google Scholar databases. Nine English-language measures met the inclusion criteria and were analyzed. The readability of each measure was analyzed via 4 validated formulas, Gunning Fog, Simple Measure of Gobbledygook, FORCAST, and Flesch Reading Ease, through an external website (readable.com). Measures with an average readability greater than 6.00 were considered above the recommended reading level.</p><p><p><b>Results:</b> All measures had at least 1 component (instructions or items) written above the recommended reading level. The mean reading level of the instructions and items sections were 9.35 (SD = 1.45; range, 7.03-11.51) and 8.78 (SD = 1.73; range, 5.59-11.31), respectively.</p><p><p><b>Conclusion:</b> The results indicate that using these measures in populations with low reading literacy may be a limitation in correctly identifying manic and depressive symptomology. If the self-report symptom tool is utilized with a higher readability than the average patient, it may not be guaranteed that this tool will improve the diagnosis process.</p><p><p><i>Prim Care Companion CNS Disord 2025;27(3):24m03892</i>.</p><p><p>\u0000 <i>Author affiliations are listed at the end of this article.</i>\u0000 </p>","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144620651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rafael Thomaz da Costa, Marcele R de Carvalho, Antonio E Nardi
{"title":"Conflict Mediation by Cognitive-Behavioral Therapy: A New Psychotherapeutic Strategy.","authors":"Rafael Thomaz da Costa, Marcele R de Carvalho, Antonio E Nardi","doi":"10.4088/PCC.24m03895","DOIUrl":"https://doi.org/10.4088/PCC.24m03895","url":null,"abstract":"<p><p><b>Objective:</b> To test the effectiveness of a psychotherapeutic strategy-the want/ can/must (WCM) strategy-to mediate conflicts. This intervention aimed to (1) facilitate the collection and sharing of information among the individuals involved and with therapists; (2) comprehend what each person wants, can, and must do; (3) alleviate psychological distress associated with decision-making and action implementation; and (4) minimize harm to all parties involved in the conflict.</p><p><p><b>Methods:</b> Thirty adult subjects experiencing a conflict situation participated in 8 cognitive-behavioral therapy sessions: 3 sessions for assessment and therapeutic bond building and 5 sessions to implement the WCM strategy. Depressive, anxious, and stress symptoms were assessed and compared before and after the intervention.</p><p><p><b>Results:</b> Depending on client and contextual factors, employing the WCM strategy, it was possible to apply techniques that promote cognitive restructuring, psychological acceptance, defusion, and impulse control and that foster compassion and self-compassion, enhance empathetic connection, foster mindfulness in social interactions, and facilitate assertive communication. There was a statistically significant decrease in Perceived Stress Scale scores (P ≤ .05).</p><p><p><b>Conclusion:</b> All participants reported that the WCM strategy aided in comprehending conflict variables, identifying how to collect information, sharing information about the conflict, accepting that there would be no \"perfect solution,\" and making a decision with the intention of minimizing harm to those involved in the conflict.</p><p><p><i>Prim Care Companion CNS Disord 2025;27(3):24m03895</i>.</p><p><p>\u0000 <i>Author affiliations are listed at the end of this article.</i>\u0000 </p>","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144620650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}