The primary care companion for CNS disorders最新文献_第2页

Dizziness: An Approach to Diagnosis and Treatment. 头晕：一种诊断与治疗方法。

The primary care companion for CNS disorders Pub Date : 2025-09-18 DOI: 10.4088/PCC.25f03967

James K Rustad, Michalla Braford, Elyse Nguyen, Lynne Boone, Jacob Weber, Shannon Ford, Theodore A Stern

引用次数: 0

Imipramine-Induced Catatonia in a Patient With Primary Nocturnal Enuresis and Emerging Bipolar Affective Disorder. 原发性夜间遗尿和新发双相情感障碍患者丙咪嗪诱发的紧张症。

The primary care companion for CNS disorders Pub Date : 2025-09-18 DOI: 10.4088/PCC.25cr03961

Tanvi Mittal, Nishanth Jalaja Haridas

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Antihistamines: Indications, Interactions, and Adverse Effects. 抗组胺药：适应症、相互作用和副作用。

The primary care companion for CNS disorders Pub Date : 2025-09-16 DOI: 10.4088/PCC.25f03958

Matthew Gunther, Austin Valido, Shixie Jiang, Theodore A Stern

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Amnesia Associated With Recreational Cannabis Use in an Adolescent. 青少年消遣性大麻使用相关的健忘症。

The primary care companion for CNS disorders Pub Date : 2025-09-16 DOI: 10.4088/PCC.23cr03562

Kaushal Shah, Sushma Srinivas, Sahar Ashraf, Faisal Kagadkar, Dhwani Kamrai, Shailesh Jain

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Impact of the COVID-19 Pandemic on the Mental Health of Middle-Aged and Older Adults: A Cross-Sectional, Comparative Study. 新冠肺炎疫情对中老年人心理健康的影响：一项横断面比较研究

The primary care companion for CNS disorders Pub Date : 2025-09-11 DOI: 10.4088/PCC.25m03963

Preethy Kathiresan, Shanaya Rathod, Yatan Pal Singh, Peter Phiri, Rachna Bhargava

{"title":"Impact of the COVID-19 Pandemic on the Mental Health of Middle-Aged and Older Adults: A Cross-Sectional, Comparative Study.","authors":"Preethy Kathiresan, Shanaya Rathod, Yatan Pal Singh, Peter Phiri, Rachna Bhargava","doi":"10.4088/PCC.25m03963","DOIUrl":"10.4088/PCC.25m03963","url":null,"abstract":"Objective: To identify differences in the impact of COVID-19 on mental health in middle-aged and older adults in India.Methods: An online web-based cross- sectional study was carried out in 8 countries during the COVID-19 pandemic. The current study analyzed data from India (the survey was conducted between July 2020 and September 2020). The selection criteria were having internet access, residing in India, and age at least 35 years. Participants aged ≥55 years were categorized as older adults and those aged 35-54 years as middle aged. Data were collected using a structured questionnaire and the Patient Health Questionnaire-9, Generalized Anxiety Disorder Scale-7, and Loneliness Scale.Results: The final analysis included 181 older adults and 321 middle-aged adults. There was a higher prevalence of depression and anxiety disorder among middle-aged adults compared to older adults. The difference was significant for depression (χ2=15.09, P<.001), but not for anxiety disorder. Logistic regression analysis found that after adjustment for sociodemographic and psychosocial variables, the presence of either depression or anxiety was significantly associated with age, perception of knowledge of COVID-19, lack of companion, feeling isolated, and feeling left out.Conclusion: Older adults were found to have less depression and anxiety disorder compared to middle-aged adults. Loneliness and perception of knowledge about COVID-19 can affect the association between the presence of mental illness and age.Prim Care Companion CNS Disord 2025;27(5):25m03963.\u0000 Author affiliations are listed at the end of this article.\u0000 ","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145055579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge of Electroconvulsive Therapy for Treatment of Catatonia. 电痉挛疗法治疗紧张症的知识。

The primary care companion for CNS disorders Pub Date : 2025-09-11 DOI: 10.4088/PCC.25lr04006

Randall T Espinoza, Charles H Kellner

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What Internists and Neurologists Know and Think About Catatonia: Reply to Espinoza and Kellner. 内科医生和神经学家对紧张症的了解和思考：回复埃斯皮诺萨和凯尔纳。

The primary care companion for CNS disorders Pub Date : 2025-09-11 DOI: 10.4088/PCC.25lr04006a

Japsimran Kaur, Daniel D Maeng, Joshua Wortzel, Mark A Oldham

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Toward Precision Psychiatry: Innovations and Prospects in Treating Depression. 走向精准精神病学：抑郁症治疗的创新与展望。

The primary care companion for CNS disorders Pub Date : 2025-09-09 DOI: 10.4088/PCC.25nr03970

Daphna Laifenfeld, Claudia Albeldas, Talia Cohen Solal, Roger S McIntyre, Stephen Stahl

{"title":"Toward Precision Psychiatry: Innovations and Prospects in Treating Depression.","authors":"Daphna Laifenfeld, Claudia Albeldas, Talia Cohen Solal, Roger S McIntyre, Stephen Stahl","doi":"10.4088/PCC.25nr03970","DOIUrl":"10.4088/PCC.25nr03970","url":null,"abstract":"Importance: Major depressive disorder is a heterogeneous disorder affecting over 280 million people globally. Despite multiple treatment options, individual response to drugs varies significantly, and most patients go through a trial-and-error approach, resulting in multiple drug iterations before alleviation of symptoms is achieved. Treatment optimization is further complicated by lack of full elucidation of the neurobiology of depression. The high prevalence of nonresponse, coupled with the detrimental effects of prolonged disease on patient welfare, economic burden, and increased likelihood of recurrence, substantiates the critical need for robust tools capable of precisely matching patients with their most effective and safe treatment options in a time-sensitive manner.Observations: Research into technologies that tailor treatments to individual patients based on their unique molecular and cellular characteristics has led to the development of precision medicine tools ranging from pharmacogenetics through peripheral biomarkers and neuroimaging to a platform that uses patient-derived neurons as a substrate for in vitro patient-specific functional readouts.Conclusions and relevance: Novel precision medicine tools in depression are being introduced that aim to identify the optimal treatment for each patient. Such tools have the potential to significantly improve depression management by guiding treatment selection for prescribers and people with lived experience.Prim Care Companion CNS Disord 2025;27(5):25nr03970.\u0000 Author affiliations are listed at the end of this article.\u0000 ","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145055924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Navigating Bell's Mania and Catatonia: The Role of Electroconvulsive Therapy in Adolescent Psychiatry. 导航贝尔狂躁症和紧张症：电痉挛疗法在青少年精神病学中的作用。

The primary care companion for CNS disorders Pub Date : 2025-09-09 DOI: 10.4088/PCC.25cr03953

Aren A Forster, Nicholas S McDuffee, Kaushal Shah, Preston Easterday

引用次数: 0

Incretin Therapies: A New Tool to Combat Metabolic Consequences of Antipsychotic Use. 肠促胰岛素治疗：对抗抗精神病药物使用代谢后果的新工具。

The primary care companion for CNS disorders Pub Date : 2025-09-04 DOI: 10.4088/PCC.25nr03924

Amre A Elmaoued, Raechel T White

{"title":"Incretin Therapies: A New Tool to Combat Metabolic Consequences of Antipsychotic Use.","authors":"Amre A Elmaoued, Raechel T White","doi":"10.4088/PCC.25nr03924","DOIUrl":"10.4088/PCC.25nr03924","url":null,"abstract":"Context: Antipsychotic medications are associated with significant metabolic risks including weight gain, lipid abnormalities, and glucose intolerance. Incretin therapies could have massive potential to benefit patients affected by antipsychotic-induced weight gain. However, patients with psychiatric disorders were often excluded from clinical trials, leaving safety and efficacy in this population largely unexplored.Evidence Acquisition: A narrative review was conducted to evaluate the data surrounding use of incretin therapies to mitigate metabolic consequences of antipsychotics and to review general safety and efficacy data relevant to prescribing of these agents to be distilled for the psychiatric provider. Package inserts, relevant clinical guidelines, and cardiometabolic outcomes trials were reviewed in developing the prescribing guide.Results: Limited data suggest that incretin therapies may be effectively utilized in patients with psychiatric conditions. A prescribing guide and algorithm were developed and include information on selecting an agent based on comorbidities, dosing and prescribing, contraindications, and clinical pearls that may be of use to providers who wish to utilize incretin therapies in patients with psychiatric comorbidities.Conclusion: Incretin therapies are highly effective medications for diabetes and weight management in the general population. While additional monitoring may be warranted in patients with psychiatric conditions, these agents are potentially effective and safe for use in treating obesity or overweight and diabetes in this population.Prim Care Companion CNS Disord 2025;27(5):25nr03924.\u0000 Author affiliations are listed at the end of this article.\u0000 ","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145055587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0