The primary care companion for CNS disorders最新文献

{"title":"Onco-Psychopharmacology: Is Mirtazapine a Catholicon?","authors":"Ahmed Naguy","doi":"10.4088/PCC.25lr03918","DOIUrl":"https://doi.org/10.4088/PCC.25lr03918","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paroxysmal Eye Movements in Treatment-Resistant Schizophrenia: Oculogyric Crisis or Seizure-Like Activity.","authors":"Carol Lim, Rachel Conrad, Saad Rahmat, David Bargiela, Oliver Freudenreich","doi":"10.4088/PCC.25cr03951","DOIUrl":"https://doi.org/10.4088/PCC.25cr03951","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Charles Bonnet Syndrome in a Patient With Multiple Sclerosis: A Rare Presentation of Complex Visual Hallucinations Associated With Optic Neuritis.","authors":"Tanvi Mittal, Nishanth Jalaja Haridas","doi":"10.4088/PCC.24cr03865","DOIUrl":"https://doi.org/10.4088/PCC.24cr03865","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time-Limited Teaching of Psychiatry to Medical Students: Flipping the Classroom and Offering Layered Learning.","authors":"Jeong Hoo Lee, James K Rustad, Linda J Herrera Santos, Patrick Ho, Theodore A Stern","doi":"10.4088/PCC.25f03944","DOIUrl":"https://doi.org/10.4088/PCC.25f03944","url":null,"abstract":"<p><p>The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. These discussions have given rise to rounds reports that will prove useful for clinicians practicing at the interface of medicine and psychiatry.</p><p><p><i>Prim Care Companion CNS Disord 2025;27(3):25f03944</i>.</p><p><p>\u0000 <i>Author affiliations are listed at the end of this article.</i>\u0000 </p>","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facing Intensive Care: A Guide for Primary Care Providers.","authors":"Sofia E Matta, Ewa D Bieber, Melissa Bui, Michalla Braford, Dana S Hardin, Joseph Dragonetti, O Joseph Bienvenu, Theodore A Stern","doi":"10.4088/PCC.24f03908","DOIUrl":"https://doi.org/10.4088/PCC.24f03908","url":null,"abstract":"<p><p>The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. These discussions have given rise to rounds reports that will prove useful for clinicians practicing at the interface of medicine and psychiatry.</p><p><p><i>Prim Care Companion CNS Disord 2025;27(3):24f03908</i>.</p><p><p>\u0000 <i>Author affiliations are listed at the end of this article.</i>\u0000 </p>","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recognizing Cotard Syndrome in the Emergency Department Setting.","authors":"Monica A Nava Frenier, Ashish Sharma, Jeana Benton","doi":"10.4088/PCC.25cr03921","DOIUrl":"https://doi.org/10.4088/PCC.25cr03921","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144286567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Need for Community-Based Alternatives to Law Enforcement in Behavioral Crisis Transport.","authors":"Kaushal Shah, Sahil Munjal","doi":"10.4088/PCC.24lr03896","DOIUrl":"https://doi.org/10.4088/PCC.24lr03896","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144286566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of GLP-1 Agonists in Psychiatric Illnesses: A Scoping Review.","authors":"Mohsan Ali, Ayesha Ahmed, Basim Ahmed Khan, Syeda Taleha Shah, Sadiq Naveed, Nauman Ashraf","doi":"10.4088/PCC.24nr03828","DOIUrl":"10.4088/PCC.24nr03828","url":null,"abstract":"<p><p><b>Importance:</b> GLP-1 receptor agonists (GLP-1 RAs) are widely recognized for their antidiabetic properties, primarily due to their insulin secretagogue action. However, their potential therapeutic effects extend beyond the endocrine system, suggesting a promising role in the treatment of psychiatric disorders. Despite this potential, there is limited consolidation of evidence regarding their psychiatric applications. This scoping review aims to address this gap by exploring the effects of GLP-1 RAs across various psychiatric conditions, highlighting their therapeutic promise and the need for further investigation.</p><p><p><b>Observations:</b> A comprehensive literature search was conducted using PubMed, Web of Science, Scopus, ClinicalTrials.gov, and PsycNet to identify studies examining the effects of GLP-1 RAs on psychiatric disorders. Original articles were included in the analysis. The findings suggest that GLP-1 RAs show efficacy in several areas, including autism-related disorders and depression. Conversely, GLP-1 RAs demonstrated no significant benefits in improving neurocognition or psychosocial functioning in schizophrenia, cocaine addiction, or dementia. Limited evidence also points to their effects on anxiety and cognitive functioning in dementia, but these findings were inconclusive.</p><p><p><b>Conclusions and Relevance:</b> The current evidence underscores the potential of GLP-1 RAs as a novel therapeutic approach for certain psychiatric disorders, particularly alcohol-related disorders, depression, and autism-related food behaviors. However, their utility in other conditions, such as schizophrenia, cocaine addiction, and dementia, remains unsupported by robust evidence. The findings highlight the importance of conducting well-designed, long-term studies to elucidate the mechanisms and clinical applications of GLP-1 RAs in psychiatry. With further research, GLP-1 RAs could expand the therapeutic arsenal for psychiatric care, offering new hope for conditions with limited treatment options.</p><p><p><i>Prim Care Companion CNS Disord 2025;27(3):24nr03828</i>.</p><p><p>\u0000 <i>Author affiliations are listed at the end of this article.</i>\u0000 </p>","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144286563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Excited Catatonia in the Setting of Concurrent Opioid and Benzodiazepine Withdrawal.","authors":"Joe G Levey, VaKara M Meyer Karre, Alëna A Balasanova","doi":"10.4088/PCC.25cr03927","DOIUrl":"https://doi.org/10.4088/PCC.25cr03927","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144286564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"β-Blocker and Colchicine Coingestion in the Setting of Cocaine Intoxication.","authors":"Olivia Levine, Souparno Mitra","doi":"10.4088/PCC.25cr03920","DOIUrl":"https://doi.org/10.4088/PCC.25cr03920","url":null,"abstract":"","PeriodicalId":22814,"journal":{"name":"The primary care companion for CNS disorders","volume":"27 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144286568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}