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Global and Regional Health Technology Assessment最新文献

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Il Significato di un titolo: Global e Regional Health Technology Assessment 2 .全球区域卫生技术评估
Global and Regional Health Technology Assessment Pub Date : 2014-12-06 DOI: 10.33393/grhta.2014.311
C. Lucioni
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引用次数: 1
Economic Impact of Therapeutic Choices: The Case of Incretins 治疗选择的经济影响:肠促胰岛素的案例
Global and Regional Health Technology Assessment Pub Date : 2014-11-21 DOI: 10.5301/GRHTA.5000181
R. Ravasio
{"title":"Economic Impact of Therapeutic Choices: The Case of Incretins","authors":"R. Ravasio","doi":"10.5301/GRHTA.5000181","DOIUrl":"https://doi.org/10.5301/GRHTA.5000181","url":null,"abstract":"The objective of this economic evaluation was to compare two alternative therapeutic regimens for the treatment of type 2 diabetes: basal-bolus insulin vs basal insulin and DPP-4. We conducted a Cost-Minimization Analysis (CMA) to compare the annual cost of basal-bolus insulin regimen vs basal insulin and DPP-4 regimen from the perspective of the Italian National Health Service (NHS). The CMA considered only direct medical costs (basal insulin, bolus insulin and DPP-4 [sitagliptin] and self-monitoring of glycemic control). Costs were assessed in 2014 Euros. Sensitivity analysis and threshold analysis on key economic parameters were performed. The expected annual cost (per patient) was €987.60 with basal insulin and DPP-4 and €1,568.23 with basal-bolus insulin. As a consequence of a significant reduction of glycemic control costs, the regimen with DPP-4 was a cost-saving alternative from the perspective of the Italian NHS.","PeriodicalId":228031,"journal":{"name":"Global and Regional Health Technology Assessment","volume":"295 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116224509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Equivalence, Similarity, Comparability, and Inter-Changeability of Pharmaceuticals: The Difficult way to Their Practical Application in Italy 药品的等效性、相似性、可比性和互换性:意大利实际应用的困难之路
Global and Regional Health Technology Assessment Pub Date : 2014-06-23 DOI: 10.33393/grhta.2014.314
M. de Rosa
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引用次数: 0
New Oncological Drugs: Analysis of Survival Gain 新的肿瘤药物:生存增益分析
Global and Regional Health Technology Assessment Pub Date : 2014-06-12 DOI: 10.5301/GRHTA.2014.12359
Nicoletta Martone, C. Lucioni, S. Mazzi, V. Fadda
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引用次数: 4
Health Technology Assessment and vaccinations in Italy 意大利的卫生技术评估和疫苗接种
Global and Regional Health Technology Assessment Pub Date : 2014-06-12 DOI: 10.5301/GRHTA.2014.12360
R. Gasparini, D. Amicizia, Piero Luigi Lai, C. Lucioni, D. Panatto
{"title":"Health Technology Assessment and vaccinations in Italy","authors":"R. Gasparini, D. Amicizia, Piero Luigi Lai, C. Lucioni, D. Panatto","doi":"10.5301/GRHTA.2014.12360","DOIUrl":"https://doi.org/10.5301/GRHTA.2014.12360","url":null,"abstract":"Vaccines are a basic investment in the long term, both for Countries and the whole world – where they are estimated to save 2.5 million lives among children each year. In this perspective vaccine r...","PeriodicalId":228031,"journal":{"name":"Global and Regional Health Technology Assessment","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127755336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Pitfalls in Clinical Research. The Case of the New Antineoplastic Agents 临床研究中的陷阱。新型抗肿瘤药物的案例
Global and Regional Health Technology Assessment Pub Date : 2014-02-12 DOI: 10.5301/GRHTA.5000183
E. Ballatori, F. Roila, B. Ruggeri
{"title":"Pitfalls in Clinical Research. The Case of the New Antineoplastic Agents","authors":"E. Ballatori, F. Roila, B. Ruggeri","doi":"10.5301/GRHTA.5000183","DOIUrl":"https://doi.org/10.5301/GRHTA.5000183","url":null,"abstract":"","PeriodicalId":228031,"journal":{"name":"Global and Regional Health Technology Assessment","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125117052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost-Effectiveness Evaluation of Oncological Drugs Newly Marketed in Italy 意大利新上市肿瘤药物的成本-效果评价
Global and Regional Health Technology Assessment Pub Date : 2014-02-12 DOI: 10.5301/GRHTA.5000182
Nicoletta Martone, C. Lucioni, S. Mazzi, V. Fadda
{"title":"Cost-Effectiveness Evaluation of Oncological Drugs Newly Marketed in Italy","authors":"Nicoletta Martone, C. Lucioni, S. Mazzi, V. Fadda","doi":"10.5301/GRHTA.5000182","DOIUrl":"https://doi.org/10.5301/GRHTA.5000182","url":null,"abstract":"In a previous publication, the incremental overall survival (OS gain vs current therapy) was estimated for the 32 new cancer therapies authorized in Italy between 2010 and 2013.The objective of this article was to quantify the respective incremental costs (including possible regulatory agreements) in order to build incremental cost-effectiveness ratios (ICERs) to be used for economic evaluation.In a first group of 12 therapies, where OS gains were statistically significant (p < 0.05), the ICERs' median value was €53,273 per year gained (range: 3,945 - 179,098) and the mean value was €64,181 (95% CI: 29,302 - 99,060). In the other group, excluding four therapies with negative OS gains, ICERs were calculated for the remaining 16 drugs. The median ICER resulted in €69,568 (range: 3,406 - 308,928) and the mean value was €87,330 (95% CI: 37,024 - 137,636).Assuming a threshold of €5,000 per life-month gained, a total of 14 new cancer therapies met this criterion of economic acceptability (eight out of 12 in the...","PeriodicalId":228031,"journal":{"name":"Global and Regional Health Technology Assessment","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132282926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Cost-Effectiveness Studies in HIV Treatment with Lopinavir/Ritonavir: A Review 洛匹那韦/利托那韦治疗HIV的成本-效果研究综述
Global and Regional Health Technology Assessment Pub Date : 2014-02-12 DOI: 10.5301/GRHTA.5000184
P. Codella, S. Coretti, A. Fiore, G. Rizzardini, M. Ruggeri
{"title":"Cost-Effectiveness Studies in HIV Treatment with Lopinavir/Ritonavir: A Review","authors":"P. Codella, S. Coretti, A. Fiore, G. Rizzardini, M. Ruggeri","doi":"10.5301/GRHTA.5000184","DOIUrl":"https://doi.org/10.5301/GRHTA.5000184","url":null,"abstract":"","PeriodicalId":228031,"journal":{"name":"Global and Regional Health Technology Assessment","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131415873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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