The Journal of the Association of Physicians of India最新文献

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Quadrivalvular Heart Disease Complicated by Fatal Infective Endocarditis of Pulmonary Valve: A Case Report.
The Journal of the Association of Physicians of India Pub Date : 2025-04-01 DOI: 10.59556/japi.73.0913
Shankar Yallappa Machigar, Akash Shah, Satyavan Sharma
{"title":"Quadrivalvular Heart Disease Complicated by Fatal Infective Endocarditis of Pulmonary Valve: A Case Report.","authors":"Shankar Yallappa Machigar, Akash Shah, Satyavan Sharma","doi":"10.59556/japi.73.0913","DOIUrl":"https://doi.org/10.59556/japi.73.0913","url":null,"abstract":"<p><p>A middle-aged sick male with rheumatic heart disease and prior mitral and aortic prosthesis was admitted for tricuspid valve replacement. Preoperative assessment revealed a hitherto undiagnosed pulmonic condition. This unusual case is reported not only to highlight the quadrivalvular disease with possible coexisting rheumatic and congenital etiology but also the fulminant endocarditis of pulmonary valve.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 4","pages":"87-89"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding Body Composition Analysis in Obesity Management.
The Journal of the Association of Physicians of India Pub Date : 2025-04-01 DOI: 10.59556/japi.73.0846
Khushboo Agarwal, Felix Manoharan, Nitin Kapoor
{"title":"Understanding Body Composition Analysis in Obesity Management.","authors":"Khushboo Agarwal, Felix Manoharan, Nitin Kapoor","doi":"10.59556/japi.73.0846","DOIUrl":"https://doi.org/10.59556/japi.73.0846","url":null,"abstract":"<p><p>The incidence of lifestyle diseases, namely obesity, diabetes mellitus, hypertension, metabolic syndrome, etc., is increasing across the world. There are different phenotypes of obesity, and body composition analysis has now become an essential part of clinical practice. It is needed to provide a better understanding of the functional capacity of the body, the muscle composition, and the amount of fat in various parts of the body.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 4","pages":"11-17"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic Stable Angina.
The Journal of the Association of Physicians of India Pub Date : 2025-04-01 DOI: 10.59556/japi.73.0885
Vitull Kumar Gupta, Meghna Gupta, Manpreet Singh Brar
{"title":"Chronic Stable Angina.","authors":"Vitull Kumar Gupta, Meghna Gupta, Manpreet Singh Brar","doi":"10.59556/japi.73.0885","DOIUrl":"https://doi.org/10.59556/japi.73.0885","url":null,"abstract":"","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 4","pages":"101"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Retrospective Study of Clinical Characteristics and Serological Profile of Male Systemic Lupus Erythematosus Patients in India.
The Journal of the Association of Physicians of India Pub Date : 2025-04-01 DOI: 10.59556/japi.73.0893
Abhishek Kumar, Vivek Vasdev, J Sankar, S Kartik, Ramakant Singh, Kunal Kishore, M Harish Kumar, Arun Hegde, Varghese Koshy, M N Arjun, Nidhi Goel
{"title":"A Retrospective Study of Clinical Characteristics and Serological Profile of Male Systemic Lupus Erythematosus Patients in India.","authors":"Abhishek Kumar, Vivek Vasdev, J Sankar, S Kartik, Ramakant Singh, Kunal Kishore, M Harish Kumar, Arun Hegde, Varghese Koshy, M N Arjun, Nidhi Goel","doi":"10.59556/japi.73.0893","DOIUrl":"https://doi.org/10.59556/japi.73.0893","url":null,"abstract":"<p><strong>Objective: </strong>Systemic lupus erythematosus (SLE) is a female-preponderant disease, and a few studies from outside India have observed that the clinical characteristics of SLE in male patients vary from those of females. There is a lack of data about SLE in male patients in the Indian subcontinent. Hence, we have reported our observations on the various clinical characteristics of SLE in male patients in this retrospective 5-year cohort study.</p><p><strong>Methods: </strong>This was a retrospective case record-based study at a tertiary care rheumatology center in North India. Records of all the SLE patients of all age-groups maintained with the department over 5 years were perused. All the patients fulfilling either of the classification criteria, viz., American College of Rheumatology (ACR) 1997 criteria and Systemic Lupus International Collaborating Clinics (SLICC) 2012, were included in the study. Data on clinical features were retrieved at the presentation and during the follow-up, immunological profile, treatment received, and long-term complications.</p><p><strong>Results: </strong>Records of 45 patients were included in the study, of which two were juvenile lupus. Mucocutaneous manifestations were the most common clinical presentation and minor organ involvement. Among the major organs, renal involvement was the most common, followed by hematological manifestations. Two patients had thrombotic manifestations. Four patients had overlap with other connective tissue disorders. Hypertension was the most common complication developed during follow-up, followed by avascular necrosis (AVN) of the femoral head. Two patients died during follow-up. Eleven patients were tested for antiphospholipid syndrome (APS) antibodies, of which one lupus anticoagulant (LAC)-positive patient had thrombotic complications. All patients were antinuclear antibodies (ANA) positive, with a speckled pattern being common, and anti-double-stranded deoxyribonucleic acid (anti-dsDNA) was the common antibody. All patients received hydroxychloroquine and low-dose steroids, and up to 35% received steroid-sparing agents. Most patients with lupus nephritis (LN) took >1 year to achieve clinical remission.</p><p><strong>Conclusion: </strong>Our study showed that male SLE patients are at high risk of severe organ damage at an early age and are susceptible to various other complications during follow-up. This may differ from female SLE patients, and larger studies in the future can further enlighten tailored treatment approaches in male patients. Ethical consent was taken wide letter no. IEC Reg. no. 54/2024 AH RR.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 4","pages":"42-47"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Jail Syndrome.
The Journal of the Association of Physicians of India Pub Date : 2025-04-01 DOI: 10.59556/japi.73.0886
Rajesh Agrawal
{"title":"Jail Syndrome.","authors":"Rajesh Agrawal","doi":"10.59556/japi.73.0886","DOIUrl":"https://doi.org/10.59556/japi.73.0886","url":null,"abstract":"<p><p>\"Jail syndrome\" is a condition emerging in individuals of high profile and status facing legal repercussions due to involvement in corruption or other illegal activities. This syndrome encompasses a spectrum of symptoms, including anxiety, panic attacks, and psychosomatic symptoms such as chest pain, headache, hysterical attacks, and many more with minimal positive investigations and other evaluations. Its prevalence is notably high among high-profile individuals such as politicians and bureaucrats in contexts marked by corruption, especially in India. The onset of symptoms typically occurs in response to arrest or legal proceedings, complicating clinical diagnosis due to the lack of identifiable organic causes. Distinguishing jail syndrome from genuine medical conditions such as acute coronary syndromes is crucial for effective management. The syndrome reflects a circumstantial diagnosis influenced by the psychological stress of legal consequences, necessitating a careful assessment of both psychological and physiological health. Large-scale studies, research, and data analysis are essential to validate jail syndrome as a recognized clinical diagnosis. Jail syndrome is a self-explanatory clinical diagnosis to convey the onset of symptomatology, etiopathology, and treatment strategy in a person involved in illicit activities with history of charges, imprisonment, or sentencing to jail. Most important is to rule out organic disease because many times organic causes such as acute coronary syndrome, diabetes mellitus (DM), and hypertension (HT) are present. Very important is that large-scale data and their scientific analysis are required to confirm and recognize it as a definite clinical diagnosis of \"jail syndrome.\" No doubt the term jail syndrome is self-explanatory and conveys the message we want to convey.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 4","pages":"98-99"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Posterior Reversible Encephalopathy Syndrome in Chronic Kidney Disease: Meta-summary of Case Reports.
The Journal of the Association of Physicians of India Pub Date : 2025-04-01 DOI: 10.59556/japi.73.0910
Deven Juneja, Ravi Jain, Prashant Nasa
{"title":"Posterior Reversible Encephalopathy Syndrome in Chronic Kidney Disease: Meta-summary of Case Reports.","authors":"Deven Juneja, Ravi Jain, Prashant Nasa","doi":"10.59556/japi.73.0910","DOIUrl":"https://doi.org/10.59556/japi.73.0910","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this meta-summary was to identify the patient profile, symptomology, risk factors, and outcomes of chronic kidney disease (CKD) patients with posterior reversible encephalopathy syndrome (PRES) by reviewing published case reports and series.</p><p><strong>Methodology: </strong>For this meta-summary, we performed a methodical search of PubMed, Google Scholar, and Reference Citation Analysis databases. We used the following search terms: \"chronic kidney failure,\" \"chronic renal insufficiency,\" AND \"hypertensive encephalopathy,\" \"PRES,\" \"reversible posterior leukoencephalopathy syndrome,\" OR \"posterior leukoencephalopathy syndrome\" in combination. The obtained results were then filtered for case reports published in English and on adult (above 18 years) humans. The relevant literature pertaining to CKD and PRES was manually screened, and duplicate articles from different databases were removed.</p><p><strong>Results: </strong>A total of 19 case reports and 9 case series with 41 patients meeting the inclusion criteria were included in the final analysis. Commonly reported symptoms were seizures (65.9%) and headache (58.5%). Visual disturbances, varying from blurred vision to cortical blindness, were reported by 36.6% of cases. In two patients, PRES was the first manifestation of CKD. Underlying hypertension was reported in 51.2% of cases, but severe hypertension was reported by 70.7% of patients at the time of presentation. Only 14.6% of patients were posttransplant on immunosuppressive therapy. Along with supportive therapy, modification of antihypertensive therapy was reported in 78.1% of cases. The need for intensive care unit (ICU) admission was reported in 43.9% of cases, with 17.1% of patients requiring invasive mechanical ventilation. The majority of patients completely recovered by the time of discharge, with only 19.5% of cases reporting residual neurological deficit. The median time for reversal was 10.5 days, and only three deaths were reported.</p><p><strong>Conclusion: </strong>CKD patients may be particularly vulnerable to developing PRES. However, due to nonspecific symptomatology overlapping with several other more common causes of neurological dysfunction in these patients, PRES may be largely missed and underdiagnosed. It may also present without any associated severe hypertension or a background of immunosuppressive therapy, which makes the diagnosis even more difficult. Blood pressure management, along with anti-edema measures and supportive care, may lead to complete recovery.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 4","pages":"e1-e5"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spectrum of Thyroid Disorders in Rheumatoid Arthritis.
The Journal of the Association of Physicians of India Pub Date : 2025-04-01 DOI: 10.59556/japi.73.0907
Megha S Kumar, Shiji Pallivalappil, Adarsh S Nair
{"title":"Spectrum of Thyroid Disorders in Rheumatoid Arthritis.","authors":"Megha S Kumar, Shiji Pallivalappil, Adarsh S Nair","doi":"10.59556/japi.73.0907","DOIUrl":"https://doi.org/10.59556/japi.73.0907","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory arthritis involving 0.5-1% of the global population. Coexistence of RA and thyroid dysfunction is now increasingly being recognized. This is due to the shared factors involved in the pathogenesis of RA and autoimmune thyroid disease. Thyroid disorder is an important amplifier of disease activity, thereby impairing the quality of life.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;To study the prevalence and pattern of thyroid dysfunction in RA patients, to compare the disease activity among RA patients with thyroid dysfunction and those without thyroid dysfunction, and to study the possible association between severe RA and thyroid dysfunction.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methodology: &lt;/strong&gt;A hospital-based analytical cross-sectional study was done in 165 RA patients attending the General Medicine and Rheumatology outpatient facilities of the Department of General Medicine, Government Medical College, Kozhikode, from January to December 2019. Study subjects were selected based on the inclusion and exclusion criteria. Relevant investigations were done, which included serum thyroid stimulating hormone (TSH), free thyroxine (free T4), free triiodothyronine (free T3), and anti-thyroid peroxidase antibody (anti-TPO) antibody levels. Data were analyzed using MS Excel and Statistical Package for the Social Sciences (SPSS) software. The prevalence and pattern of thyroid disorders in RA patients were assessed. The association of thyroid dysfunction with disease activity was tested.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The prevalence of thyroid dysfunction among RA patients was 38.2%. The most common thyroid disorder observed was subclinical hypothyroidism, which was seen in 33.3% (55) of the study population, followed by overt hypothyroidism in 3.6% (6) of patients. Both subclinical hyperthyroidism and clinical hyperthyroidism were found in only 0.6% of RA patients. There was a significant difference in mean age between RA patients with thyroid dysfunction and euthyroid patients (&lt;i&gt;p&lt;/i&gt;-value = 0.001). No significant association was found between the duration of RA and thyroid dysfunction (&lt;i&gt;p&lt;/i&gt;-value = 0.253). RA patients with thyroid dysfunction had elevated inflammatory markers compared to those with normal thyroid function. The prevalence of autoimmune thyroid disorder in RA patients is 24.8%. There was a significant association between disease activity and thyroid dysfunction (&lt;i&gt;p&lt;/i&gt;-value = 0.001). Patients with thyroid disorders had severe disease compared to euthyroid patients. A significant positive correlation was noted between serum TSH and Disease Activity Score-28 (DAS-28) (Pearson coefficient = 0.768, &lt;i&gt;p&lt;/i&gt;-value = 0.000), and between anti-TPO antibody and DAS-28 (Pearson coefficient = 0.794, &lt;i&gt;p&lt;/i&gt;-value = 0.000).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Thyroid dysfunction is prevalent in 38.2% of RA patients, with subclinical hypothyroidism being the most common t","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 4","pages":"18-21"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beyond Amlodipine-The Case for S-amlodipine as the First Choice Calcium Channel Blocker: An Expert Opinion from India.
The Journal of the Association of Physicians of India Pub Date : 2025-04-01 DOI: 10.59556/japi.73.0927
Jagdish Hiremath, J C Mohan, Jabir Abdullakutty, Sandeep Bansal, Jamshed Dalal, Prakash K Hazra, Sarita Rao, V T Shah, Samir Kubba
{"title":"Beyond Amlodipine-The Case for S-amlodipine as the First Choice Calcium Channel Blocker: An Expert Opinion from India.","authors":"Jagdish Hiremath, J C Mohan, Jabir Abdullakutty, Sandeep Bansal, Jamshed Dalal, Prakash K Hazra, Sarita Rao, V T Shah, Samir Kubba","doi":"10.59556/japi.73.0927","DOIUrl":"https://doi.org/10.59556/japi.73.0927","url":null,"abstract":"<p><strong>Background: </strong>Calcium channel blockers (CCBs) have been recommended as the first-line treatment option for the management of hypertension. Amlodipine has been used to treat hypertension over the past 3 decades. However, the chief limitation of amlodipine is pedal edema; it is associated with poor adherence to therapy. Amlodipine is a racemic mixture of two stereoisomers [R(+), S(-)]. Only the S(-) isomer exerts vasodilating action. The R-amlodipine isomer is considered to cause adverse effects.</p><p><strong>Aim: </strong>To understand the place of S-amlodipine and its combinations in the management of hypertension and related cardiovascular (CV) disorders in the real-world setting in India.</p><p><strong>Methodology: </strong>A conclave of nine Indian cardiologists was formed to discuss the place of S-amlodipine in the management of hypertension in their clinical practice.</p><p><strong>Results: </strong>The antihypertensive efficacy of S-amlodipine is comparable to that of amlodipine. S-amlodipine does not cause pedal edema. In fact, switching patients on amlodipine who develop pedal edema to S-amlodipine is helpful in improving patient compliance. However, it would be prudent to initiate treatment with S-amlodipine itself rather than amlodipine, which causes pedal edema. S-amlodipine does not cause gingival hypertrophy, and this improves patient compliance. S-amlodipine consistently lowers blood pressure (BP) across different patient populations such as young, elderly, and patients with CV risk factors.</p><p><strong>Conclusion: </strong>S-amlodipine has antihypertensive, antianginal actions, and pleiotropic effects. S-amlodipine 2.5 mg is found to be equivalent in its efficacy and tolerability when compared to amlodipine 5 mg in the treatment of mild to moderate hypertension.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 4","pages":"e33-e39"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of Serum Vitamin B12 and Muscle Enzyme (CK-NAC) Level with Severity of Guillain-Barre Syndrome and Its Prediction in Respiratory Failure.
The Journal of the Association of Physicians of India Pub Date : 2025-04-01 DOI: 10.59556/japi.73.0892
Vinod Singh Jatav, Vijay Sardana, Bharat Bhushan, Dilip Maheshwari, Subham Garg, Vaibhav Somvanshi, Ashwin Lathiya
{"title":"Correlation of Serum Vitamin B<sub>12</sub> and Muscle Enzyme (CK-NAC) Level with Severity of Guillain-Barre Syndrome and Its Prediction in Respiratory Failure.","authors":"Vinod Singh Jatav, Vijay Sardana, Bharat Bhushan, Dilip Maheshwari, Subham Garg, Vaibhav Somvanshi, Ashwin Lathiya","doi":"10.59556/japi.73.0892","DOIUrl":"https://doi.org/10.59556/japi.73.0892","url":null,"abstract":"<p><strong>Background: </strong>Guillain-Barré syndrome (GBS) is an acute-onset polyneuropathy. Several biomarkers have been identified to monitor prognosis in GBS, including serum folate, serum albumin, blood glucose, serum sodium, and plasma cortisol levels.</p><p><strong>Objectives: </strong>To study the prevalence of serum vitamin B<sub>12</sub> deficiency and increased creatine kinase (CK-NAC) levels in GBS patients and ascertain if the levels of serum CK-NAC and vitamin B<sub>12</sub> can serve as prognostic indicators in GBS patients.</p><p><strong>Materials and methods: </strong>The research recruited 50 patients with GBS from the neurology department of a tertiary care hospital between 2020 and 2021. The study assessed the patients' motor function deficits using the MRC (Medical Research Council) scale as well as the HDS (Hughes Disability Scale). Vitamin B<sub>12</sub> and CK-NAC levels were measured, and patients were divided into four groups, one of which had a deficiency in vitamin B<sub>12</sub> and a raised CK-NAC level, while another group had normal serum vitamin B<sub>12</sub> and CK-NAC levels. Clinical characteristics were compared. Serum vitamin B<sub>12</sub> and CK-NAC levels were associated with GBS severity based on HDS and MRC scales, autonomic dysfunction, and respiratory failure.</p><p><strong>Results: </strong>Serum vitamin B<sub>12</sub> deficiency along with elevated CK-NAC levels was discovered in 44 and 14% of GBS patients, respectively. Serum vitamin B<sub>12</sub> deficiency correlated significantly with GBS severity, including progression duration, admission and nadir HDS scores, and autonomic dysfunction (<i>p</i> < 0.05). CK-NAC level did not correlate with the severity of GBS (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>Vitamin B<sub>12</sub> levels can predict prognosis in GBS patients.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 4","pages":"48-51"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Knowledge, Attitudes, and Practices among Healthcare Professionals toward Role of Artificial Intelligence in Healthcare.
The Journal of the Association of Physicians of India Pub Date : 2025-04-01 DOI: 10.59556/japi.73.0909
Dharma Rao Vanamali, Himavathy K Gara, Venkata Anil Chandra Dronamraju
{"title":"Evaluation of Knowledge, Attitudes, and Practices among Healthcare Professionals toward Role of Artificial Intelligence in Healthcare.","authors":"Dharma Rao Vanamali, Himavathy K Gara, Venkata Anil Chandra Dronamraju","doi":"10.59556/japi.73.0909","DOIUrl":"https://doi.org/10.59556/japi.73.0909","url":null,"abstract":"<p><strong>Background: </strong>Artificial intelligence (AI) is transforming healthcare by enhancing diagnostics, treatment planning, and patient management. However, the successful integration of AI depends on healthcare professionals' (HCPs) knowledge, attitudes, and practices (KAP). The study aimed to evaluate the KAP of HCPs regarding the role of AI in healthcare. Additionally, the study aimed to identify key barriers, such as ethical concerns and technical limitations, that hinder AI adoption.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted using an online structured questionnaire targeting doctors, medical students, and nurses. The survey, distributed <i>via</i> Google Forms, measured participants' demographics, KAPs regarding AI. Purposive and snowball sampling methods were employed to recruit a total of 350 participants.</p><p><strong>Results: </strong>A total of 350 participants completed the survey, with the majority being medical students (52%) and younger professionals aged 18-27 years (73.1%). AI's primary use was in diagnostics (71.1%), followed by treatment protocol development (45.4%) and drug development (33.1%). Most respondents rated their technical skills as low or very low, with medical students showing slightly higher proficiency compared to nurses and faculty members. Ethical concerns were prominent, with 46% of participants highlighting data privacy and security issues, followed by concerns about high costs (23.7%) and over-reliance on manual processes (16.6%). Significant differences were observed between professions: medical students and faculty were more open to AI's role in making critical decisions (60.98% and 61.94%, respectively) than nurses (29.41%). Additionally, 97% of nurses expressed willingness to undergo AI training compared to 86% of faculty and 82% of medical students. However, confidence in AI's ability to improve clinical outcomes was mixed, with 35.71% agreeing, 29.71% neutral, and 40% regularly using AI tools in practice.</p><p><strong>Conclusion: </strong>The findings highlight a positive attitude toward AI in healthcare, with substantial recognition of its benefits, especially in diagnostics. However, significant gaps in knowledge, technical skills, and awareness of ethical issues remain, particularly among nurses. Tailored education and training programs are needed to bridge these gaps and enhance AI readiness in healthcare practice.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 4","pages":"e6-e12"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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