Maks Mihalj, Duc T. Nguyen, Ismael A. Salas de Armas, Sinan Tosun, Scott T. Heston, Mateja K. Jezovnik, Jayeshkumar Patel, Angelo Nascimbene, Marwan Jumean, Anju Bhardwaj, Sriram Nathan, Rajko Radovancevic, Manish K. Patel, Biswajit Kar, Igor D. Gregoric
{"title":"Aortic Insufficiency Progression in Patients with Left Ventricular Assist Devices and Prior Impella Support","authors":"Maks Mihalj, Duc T. Nguyen, Ismael A. Salas de Armas, Sinan Tosun, Scott T. Heston, Mateja K. Jezovnik, Jayeshkumar Patel, Angelo Nascimbene, Marwan Jumean, Anju Bhardwaj, Sriram Nathan, Rajko Radovancevic, Manish K. Patel, Biswajit Kar, Igor D. Gregoric","doi":"10.1016/j.healun.2026.02.1665","DOIUrl":"https://doi.org/10.1016/j.healun.2026.02.1665","url":null,"abstract":"","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"335 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146777325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oliver J F Weiner,Moloy Das,Richard H Clayton,Janet M McComb,Alan Murray,Gareth Parry,Stephen W Lord
{"title":"Sympathetic reinnervation in cardiac transplant recipients: Prevalence, time course and association with long-term survival.","authors":"Oliver J F Weiner,Moloy Das,Richard H Clayton,Janet M McComb,Alan Murray,Gareth Parry,Stephen W Lord","doi":"10.1016/j.healun.2024.10.009","DOIUrl":"https://doi.org/10.1016/j.healun.2024.10.009","url":null,"abstract":"BACKGROUNDPartial cardiac sympathetic reinnervation after cardiac transplant has been extensively investigated and evidenced. However, there have been no large-scale, long-term studies evaluating the prevalence, time-course, and association with long-term survival of sympathetic reinnervation of the heart.METHODSCardiac transplant recipients (n=232) were recruited from outpatient clinic at a single transplant centre in the United Kingdom. Participants were each tested once for the presence of sympathetic reinnervation of the sinus node using the low frequency component of power spectral analysis of heart rate variability, with a cut-off defined as 2 standard deviations above the mean for denervated participants (those tested <56 days post-transplant). Time-course was calculated based on the timing of testing post-transplant. Patients were then followed-up over a period of up to 27 years after transplant for survival analysis.RESULTSThe overall prevalence of cardiac sympathetic reinnervation in the 225 patients tested >56 days post-transplant was 64.9%. Sympathetic reinnervation primarily occurred in the first 18 months after transplant, with a plateau thereafter. The prevalence in participants tested >18 months post-transplant was 69.6%. In Kaplan-Meier survival analysis, sympathetic reinnervation was associated with significantly improved survival (Log-rank P=0.019), with a median survival time for reinnervated patients of 19.9 years compared to 14.4 years for the denervated group.CONCLUSIONSSympathetic reinnervation of the sinus node occurs mostly within 18 months of transplant, is found in 70% of cardiac transplant recipients tested >18 months post-transplant, and is associated with significantly improved long-term survival.","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142486349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bridging Gaps in Lung Allocation: A Data-Driven Approach to Overcome Biological Disparities.","authors":"Ankit Bharat","doi":"10.1016/j.healun.2024.10.008","DOIUrl":"https://doi.org/10.1016/j.healun.2024.10.008","url":null,"abstract":"","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142486342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Severe primary graft dysfunction after heart transplantation - Defining the Subtypes.","authors":"Sanjay Dutta,Peter S Macdonald","doi":"10.1016/j.healun.2024.10.010","DOIUrl":"https://doi.org/10.1016/j.healun.2024.10.010","url":null,"abstract":"","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142486279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Moraes, M. Heringer, G. Campos, L. Xavier, S. Mangini, F. Bacal
{"title":"Reactivation of Chagas Disease","authors":"S. Moraes, M. Heringer, G. Campos, L. Xavier, S. Mangini, F. Bacal","doi":"10.1016/j.healun.2024.02.1250","DOIUrl":"https://doi.org/10.1016/j.healun.2024.02.1250","url":null,"abstract":"","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"56 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140759327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Kittleson, J. Patel, A. Nikolova, M. White, N. Bhatnagar, A. Kanungo, M. Lee, E. Chow, J. Moriguchi, D. Geft, L. Czer, F. Esmailian, J. Kobashigawa
{"title":"Natural Outcome of Isolated Right Ventricular Dysfunction Immediately After Heart Transplantation","authors":"M. Kittleson, J. Patel, A. Nikolova, M. White, N. Bhatnagar, A. Kanungo, M. Lee, E. Chow, J. Moriguchi, D. Geft, L. Czer, F. Esmailian, J. Kobashigawa","doi":"10.1016/j.healun.2024.02.687","DOIUrl":"https://doi.org/10.1016/j.healun.2024.02.687","url":null,"abstract":"","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"231 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140762337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Histopathologic Changes of Primary Graft Dysfunction of the Heart","authors":"M. Ospina-Romero, J.J. Schulte","doi":"10.1016/j.healun.2024.02.617","DOIUrl":"https://doi.org/10.1016/j.healun.2024.02.617","url":null,"abstract":"","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"42 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140756394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M.U. Ahmed, F. Wright, S. Munoz, A. Albrecht, P. Weber, S. Hassan, N. Manandhar Shrestha, C. Kerndt, J. McDermott, R. Hadley, M. Gonzalez, M. Tamae Kakazu, R. Loyaga-Rendon, B. Trethowan
{"title":"Associations of Outpatient Administration of Monoclonal Antibody Therapy for COVID-19 Infection in Orthotropic Thoracic Organ Transplant Recipients","authors":"M.U. Ahmed, F. Wright, S. Munoz, A. Albrecht, P. Weber, S. Hassan, N. Manandhar Shrestha, C. Kerndt, J. McDermott, R. Hadley, M. Gonzalez, M. Tamae Kakazu, R. Loyaga-Rendon, B. Trethowan","doi":"10.1016/j.healun.2024.02.550","DOIUrl":"https://doi.org/10.1016/j.healun.2024.02.550","url":null,"abstract":"","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"7 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140766799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Balachandran, J. Patel, M. Kittleson, G. Jamero, A. Kanungo, M. Lee, N. Bhatnagar, A. Nikolova, A. Hage, M. Bowdish, L. Czer, J. Kobashigawa
{"title":"Does Crossing DSA and Its Binding Levels at the Time of Heart Transplant Impact Post-Transplant Outcomes?","authors":"I. Balachandran, J. Patel, M. Kittleson, G. Jamero, A. Kanungo, M. Lee, N. Bhatnagar, A. Nikolova, A. Hage, M. Bowdish, L. Czer, J. Kobashigawa","doi":"10.1016/j.healun.2024.02.592","DOIUrl":"https://doi.org/10.1016/j.healun.2024.02.592","url":null,"abstract":"","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"31 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140763403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Ravichandran, I. Dumitru, M. Kamath, M. Deng, K. Oreschak, P. Hanson, S. Wang, S. Hall
{"title":"Association Between Pre-Transplant Mechanical Circulatory Support Status and Donor-Derived Cell-Free DNA Levels and Gene Expression Profiling Following Heart Transplant","authors":"A. Ravichandran, I. Dumitru, M. Kamath, M. Deng, K. Oreschak, P. Hanson, S. Wang, S. Hall","doi":"10.1016/j.healun.2024.02.1451","DOIUrl":"https://doi.org/10.1016/j.healun.2024.02.1451","url":null,"abstract":"","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"50 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140767297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}