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Cystic fibrosis: diagnostic considerations. 囊性纤维化:诊断考虑。
The Johns Hopkins medical journal Pub Date : 1982-03-01
B J Rosenstein, T S Langbaum, S J Metz
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引用次数: 0
Cholesterol levels in young adulthood and subsequent cancer: a preliminary note. 青年期胆固醇水平与随后的癌症:初步说明。
The Johns Hopkins medical journal Pub Date : 1982-03-01
C B Thomas, K R Duszynski, J W Shaffer
{"title":"Cholesterol levels in young adulthood and subsequent cancer: a preliminary note.","authors":"C B Thomas,&nbsp;K R Duszynski,&nbsp;J W Shaffer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a study of the serum cholesterol of 30 male medical students who later developed major cancer, no consistent relationship between baseline cholesterol level and cancer was found during follow-up studies extending for up to 33 years. However, different cancer types seemed to have different cholesterol profiles: subjects who developed melanoma or lung cancer had relatively low initial levels, while subjects who developed cancer of the digestive system, brain or urinary bladder tended to have high initial values. Sequential cholesterol measurements made on two men with cancer of the colon are presented. It is suggested that such sequential cholesterol studies combined with knowledge of the types of cancers involved would help to clarify such complex interrelationships as may exist. The implications of a two-population hypothesis are discussed.</p>","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"150 3","pages":"89-94"},"PeriodicalIF":0.0,"publicationDate":"1982-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18109402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical conferences at the John Hopkins Hospital: alcoholic hepatitis. 约翰霍普金斯医院的临床会议:酒精性肝炎。
The Johns Hopkins medical journal Pub Date : 1982-02-01
{"title":"Clinical conferences at the John Hopkins Hospital: alcoholic hepatitis.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"150 2","pages":"65-9"},"PeriodicalIF":0.0,"publicationDate":"1982-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18104836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Normal intelligence in the Cornelia de Lange syndrome. 科妮莉亚·德·兰格综合症的正常智力。
The Johns Hopkins medical journal Pub Date : 1982-02-01
N Gadoth, M Lerman, B Z Garty, O Shmuelewitz
{"title":"Normal intelligence in the Cornelia de Lange syndrome.","authors":"N Gadoth,&nbsp;M Lerman,&nbsp;B Z Garty,&nbsp;O Shmuelewitz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"150 2","pages":"70-2"},"PeriodicalIF":0.0,"publicationDate":"1982-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18104837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of carnitine on serum HDL-cholesterol: report of two cases. 肉碱对血清高密度脂蛋白胆固醇的影响:附2例报告。
The Johns Hopkins medical journal Pub Date : 1982-02-01
C S Rossi, N Siliprandi
{"title":"Effect of carnitine on serum HDL-cholesterol: report of two cases.","authors":"C S Rossi,&nbsp;N Siliprandi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In two otherwise normal male subjects selected for normal serum cholesterol and triglycerides but low serum high-density lipoprotein (HDL) levels, oral administration of 1 g per day of L-carnitine over a period of 10-15 weeks caused a substantial increase in high-density lipoprotein levels, as well as a decrease in serum triglycerides. The ratio of HDL-cholesterol to total cholesterol increased, but this change was not due to an obligatory lowering of total cholesterol. Possible mechanisms of the carnitine effect are discussed. Since elevated high-density lipoprotein levels significantly reduce the risk of arteriosclerotic cardiovascular disease, this action of carnitine deserves further study.</p>","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"150 2","pages":"51-4"},"PeriodicalIF":0.0,"publicationDate":"1982-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18104835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implications of an expanding supply of physicians: evidence from a cross-sectional analysis. 医师供应扩大的影响:来自横断面分析的证据。
The Johns Hopkins medical journal Pub Date : 1982-02-01
K Davis
{"title":"Implications of an expanding supply of physicians: evidence from a cross-sectional analysis.","authors":"K Davis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the fall of 1980 the Graduate Medical Education National Advisory Committee (GMENAC) issued a report estimating that the supply of physicians will increase by 43% from 1978 to 1990, compared with an increase of 11% in the United States population. GMENAC estimated that this will lead to a surplus of 70,000 physicians by 1990, increasing to 145,000 by the turn of the century. Particularly marked surpluses are estimated to occur for nearly all surgical specialties, as well as most medical subspecialties. This paper attempts to estimate the impact of this increase in the supply of physicians on health care utilization and spending for health care services. Using cross-sectional data for 1978 this study estimates that an increased supply of physicians increases hospital admissions, lengths of hospital stays, costs per hospital day, physician fees for specialty services, and physician expenditures per capita. However, physician incomes appear to be lower in areas with more physicians. Projections to 1990 indicate that total health expenditures may be $50 billion higher as a result of the increase in physician supply. Real incomes of physicians, however, may be no greater than in 1978.</p>","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"150 2","pages":"55-64"},"PeriodicalIF":0.0,"publicationDate":"1982-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18026734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Familial erythroleukemia: four cases of the Diguglielmo syndrome in close relatives. 家族性红细胞白血病:近亲属中Diguglielmo综合征4例。
The Johns Hopkins medical journal Pub Date : 1982-01-01
M J Nissenblatt, W Bias, D Borgaonkar, S Dixon, R P Cody
{"title":"Familial erythroleukemia: four cases of the Diguglielmo syndrome in close relatives.","authors":"M J Nissenblatt,&nbsp;W Bias,&nbsp;D Borgaonkar,&nbsp;S Dixon,&nbsp;R P Cody","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Erythroleukemia was diagnosed in three brothers during a 6-month period in 1976. A son of one leukemic had died 5 years earlier with erythroleukemia. First-degree relatives of these men were evaluated in an attempt to identify contributing factors. Twenty-four relatives have been studied. Immunoglobulin M was elevated in 14 of 16 persons (mean, 352.8 mg/dl; normal, less than 145 mg/dl; P less than .001). This was neither a monoclonal protein nor rheumatoid factor. Age-dependent red cell enzymes were increased. Erythrocyte hexokinase was markedly increased in 23 of 24 persons (mean, 35.05 units/100 ml RBC; normal, less than 18 units; P less than .001). Evidence for a hemolytic state was absent. Bone marrow samples in 8 first-degree relatives were normal. Cytogenetics were normal in 18 relatives. One leukemic exhibited hypoploidy and a marker chromosome. The association of an immunoglobulin abnormality and enzymopathy in the leukemics and relatives alike suggests a hereditary susceptibility to the development of erythroleukemia. The exact link is not identified.</p>","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"150 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17996919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Henry M. Thomas: Johns Hopkins's first neurologist. 亨利·m·托马斯:约翰·霍普金斯大学的第一位神经学家。
The Johns Hopkins medical journal Pub Date : 1982-01-01
A M Harvey
{"title":"Henry M. Thomas: Johns Hopkins's first neurologist.","authors":"A M Harvey","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"150 1","pages":"11-21"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18081647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Streptococcus pneumoniae bacteremia without an identifiable focus in adults. 成人无可识别病灶的肺炎链球菌菌血症。
The Johns Hopkins medical journal Pub Date : 1982-01-01
K C Spitalny, K Bromberg, M B Ginsberg
{"title":"Streptococcus pneumoniae bacteremia without an identifiable focus in adults.","authors":"K C Spitalny,&nbsp;K Bromberg,&nbsp;M B Ginsberg","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"150 1","pages":"35-7"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18102110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug management in chronic schizophrenia. 慢性精神分裂症的药物管理。
The Johns Hopkins medical journal Pub Date : 1982-01-01
L E Tune, P R McHugh, J T Coyle
{"title":"Drug management in chronic schizophrenia.","authors":"L E Tune,&nbsp;P R McHugh,&nbsp;J T Coyle","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"150 1","pages":"45-8"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18102112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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