{"title":"Recovery of anti-gravity muscles in patients with consequences of limb injury","authors":"D. Somov, M. R. Makarova, Egor A. Maiorov","doi":"10.17816/rjpbr114786","DOIUrl":"https://doi.org/10.17816/rjpbr114786","url":null,"abstract":"BACKGROUND: Over the past years, injuries have been consistently included in the first seven leading classes in the structure of general morbidity, and in the distribution of the number of people aged 18 years and over who were first recognized as disabled, they are included in the first six causes of disability. \u0000AIM: to study the clinical efficacy and safety of the author's technique, in patients after injuries of the lower and upper extremities at the second stage of medical rehabilitation. \u0000MATERIALS AND METHODS: The study included 105 patients who had suffered injuries. 37 (35.2%) men, 68 (64.8%) women. The patients were randomly divided into 2 observation groups: the main group (n=53), whose patients, in addition to the standard rehabilitation program, were trained on the biofeedback simulator Tergumed Pegasus 3D (Germany), a course of 710 procedures, and the control group (n=52), whose patients underwent a course of medical rehabilitation only according to the standard program of the 2nd stage, lasting 1014 days. The complex rehabilitation treatment of patients included standard drug therapy, massage courses, physiotherapy, group exercise therapy. Treatment outcomes were assessed using the VAS (Visual Analog Scale), HAQ (Health Assessment Questionnaire), Lequesne index, and 20-m walking time scales. Data analysis included comparison of dependent series of variables and descriptive statistics methods. The type of data distribution (parametric or nonparametric) was assessed using the ShapiroWilk and KolmogorovSmirnov tests. The statistical significance of differences between dependent groups was assessed using the Wilcoxon and MannWhitney tests. The value of p=0.05 was taken as the level of statistical significance. \u0000RESULTS: All measured indicators improved significantly (p 0.001). In the main group, compared with the control group, there was a statistically significant increase in walking speed, and there was a tendency to a more pronounced positive change in the Lequesne and HAQ indices, the level of pain according to VAS, compared with the control group. \u0000CONCLUSION: Our proposed method of training with the participation of antigravity muscles trunk is effective for patients after limb injuries at the 2nd stage of medical rehabilitation.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125075547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Chkheidze, Z. Zhilokov, A. Tkachenko, N. G. Kulikova
{"title":"Reduction of glycemic risks in patients with diabetes mellitus and chronic periodontitis after physiotherapy","authors":"T. Chkheidze, Z. Zhilokov, A. Tkachenko, N. G. Kulikova","doi":"10.17816/rjpbr115067","DOIUrl":"https://doi.org/10.17816/rjpbr115067","url":null,"abstract":"BACKGROUND: The article is devoted to the actual task of reducing inflammatory complications after dental manipulations in patients with diabetes mellitus. It is noted that worldwide there is a steady trend of increasing the incidence of diabetes mellitus and predicting an increase in the number of patients to 250 million people by 2025. The prevalence, severity of dental complications and inflammatory diseases of periodontal tissues in patients with diabetes is extremely high, which determines the relevance and scientific and practical significance of the study. \u0000AIM: to evaluate the score, index dental indicators, cytokine plasma indicators before/after the use of physiotherapy methods in complex dental treatment. \u0000MATERIAL AND METHODS: The study included 121 patients (58 men and 63 women) with diabetes mellitus with an underlying disease duration of up to 5 years who were diagnosed with diabetes periodontal-periodontal inflammatory diseases. Starting and ending points: point, index dental indicators, glycemic profile and immunological cytokine plasma indicators before/after the application of physiotherapy methods before/after the application of physiotherapy methods in complex dental treatment, including a transcanal method of drug electrophoresis with a copper-calcium preparation and laser exposure to NILI (low-intensity laser radiation; l=810 nm). Analysis of statistical data was carried out in Microsoft Office Excel (2017) programs. The differences were considered significant at р 0.05. \u0000RESULTS: It has been established that the use of complex physiotherapy in patients with diabetes reduces glycemic risks and increases antioxidant reserves. \u0000CONCLUSION: The use of complex physiotherapy in patients with type 2 diabetes mellitus reduces the risks of inflammatory complications in periodontal-periodontal tissues, which is confirmed by clinical efficacy in relation to cellular immunity and hygiene index.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130134173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. N. Kolbakhova, D. Kulchitskaya, T. Khaptagaev, R. N. Strukov, E. Koneva
{"title":"The use of electrotherapy in complex treatment programs for patients after total arthroplasty","authors":"S. N. Kolbakhova, D. Kulchitskaya, T. Khaptagaev, R. N. Strukov, E. Koneva","doi":"10.17816/rjpbr115041","DOIUrl":"https://doi.org/10.17816/rjpbr115041","url":null,"abstract":"BACKGROUND: Total knee arthroplasty is one of the most common surgical interventions in the world and the Russian Federation. Endoprosthetics of the knee joint occupies a leading place in the structure of surgical methods for the treatment osteoarthritis. \u0000AIM: of the study was to scientifically substantiate the feasibility of the complex use of electrical stimulation and therapeutic exercises in patients after total knee arthroplasty. \u0000MATERIALS AND METHODS: We examined 60 patients who were admitted 3 months after TCS and were randomized into 2 groups. In the first group, 30 subjects received electrical stimulation of the quadriceps muscles and underwent therapeutic exercises, for a course of 10 procedures. The subjects of the second group, 30 people, had only physiotherapy exercises. \u0000RESULTS: The use of electrotherapy and physiotherapy exercises, in the complex treatment of patients after total knee arthroplasty, improves the function of joint mobility. This is confirmed by the improvement in the functional activity of the operated joint according to the KSS scale (Кnee Society Scores), the improvement in the state of microcirculation and the positive dynamics of the pain syndrome according to the VAS (Visual Analog Scale). The obtained data of the HAQ (Health Assessment Questionnaire) questionnaire testify to the expansion of the possibilities for performing most of the activities in everyday life. However, more statistically significant results were obtained in patients after a course of quadriceps electrical stimulation and therapeutic exercises compared with the use of therapeutic exercises alone. \u0000CONCLUSION: The complex of rehabilitation of patients after total knee arthroplasty presented by us, including electrostimulation and therapeutic gymnastics, is scientifically sound, effective and can be implemented into the basic scheme of outpatient and sanatorium treatment of this category of patients.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"344 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123057724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction of age-related changes of the face skin using radiofrequency micro needling. Brief literature review","authors":"M. A. Agapova, A. Sharova","doi":"10.17816/rjpbr115065","DOIUrl":"https://doi.org/10.17816/rjpbr115065","url":null,"abstract":"The problem of choosing a method for skin rejuvenation remains relevant despite a wide selection of conservative and surgical methods for eliminating age-related changes. In recent years, treatment methods for voluminous and traumatic ones have been striving for minimally invasive, quickly feasible with an optimal result that should meet both the needs of patients and doctors. For this reason, injection and hardware methods of rejuvenation began to come to the fore, especially when correcting changes on the face. Cosmetic devices based on radiofrequency can compete in efficiency with laser technology, having their own specific advantages. \u0000The aim of the work was to evaluate the available literature sources related to the use of radiofrequency in dermatology and dermatocosmetology, especially for leveling age-related changes in the skin of the face. \u0000The available literature sources from Russian and foreign databases (Elibrary, PubMed, Google Academia) were analyzed on the use of radiofrequency and radiofrequency micro needling in dermatocosmetology for facial skin rejuvenation. \u0000The analysis showed the widespread use of radio frequency in dermatocosmetology, its high efficiency and safety, however, there are very few full-fledged studies devoted to radio frequency microneedling. \u0000In our opinion, radiofrequency microneedling is a significant step forward compared to traditional radiofrequency devices, especially for facial skin rejuvenation by increasing the safety and effectiveness of the procedure. The use of radiofrequency microneedling can be effective for correcting age-related skin changes, especially in the face area, both as monotherapy and in combination with other methods of rejuvenation.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116720485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. V. Novikova, M. S. Petrova, Sergey N. Nikolaev, V. F. Prikuls
{"title":"Мedical rehabilitation of children with spinal dysrafism","authors":"E. V. Novikova, M. S. Petrova, Sergey N. Nikolaev, V. F. Prikuls","doi":"10.17816/rjpbr115021","DOIUrl":"https://doi.org/10.17816/rjpbr115021","url":null,"abstract":"The development of a system of staged medical care for the medical rehabilitation of children with spinal dysraphism is an important and urgent task of pediatrics. \u0000Spinal dysraphism is accompanied by flaccid paresis or paralysis of the lower extremities, as well as a violation of the function of the pelvic organs. In most cases, various deformations of the feet are observed, congenital dislocations of the hip are often found. \u0000Medical rehabilitation begins immediately after surgical treatment in intensive care units and specialized departments. At the first stage, one of the important tasks is the correction of pelvic disorders. For this purpose, electrical stimulation, drug electrophoresis, magnetotherapy are used depending on the type of neurogenic bladder dysfunction. Currently, the effectiveness of high-intensity pulsed magnetotherapy in children with areflex bladder has been proven. The second stage of medical rehabilitation should be carried out if available in rehabilitation departments, medical rehabilitation centers and aimed at correcting motor impairment. Along with instrumental physiotherapy, modern technologies of physiotherapy exercises are actively introduced, aimed at strengthening the muscles of the lower extremities, preventing muscle atrophy. \u0000The third stage of medical rehabilitation is the longest, carried out on an outpatient basis and includes various health technologies, such as aeroionotherapy, halotherapy, balneotherapy, and mud therapy. \u0000Timely implementation of rehabilitation measures with the inclusion of physical factors in the early postoperative period and the consistent expansion of physiotherapy and kinesitherapy technologies at all stages of medical rehabilitation significantly increases the effectiveness of rehabilitation of patients with spinal cord injuries and improves their quality of life.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117263570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. K. Drakon, N. Korchazhkina, Vycheslav M. Sheludchenko
{"title":"Experience of use of the extended complex of ophthalmononeurostimulation in patients with non-exudative atrophic (geographic) form of age-of-aged macular degeneration","authors":"A. K. Drakon, N. Korchazhkina, Vycheslav M. Sheludchenko","doi":"10.17816/rjpbr111022","DOIUrl":"https://doi.org/10.17816/rjpbr111022","url":null,"abstract":"BACKGROUND: Non-exudative atrophic (geographic) macular degeneration of the retina is one of the causes of irreversible loss of central vision in the elderly. Its frequency of occurrence increases with age. \u0000AIM: to evaluate the effectiveness of the extended complex of ophthalmoneurostimulation in patients with non-exudative atrophic (geographical) form of age-related macular degeneration. \u0000MATERIAL AND METHODS: The study included 49 people (98 eyes) with geographic retinal atrophy, whose average age was 741.7 years, who were divided into 2 groups: group 1 ― 24 patients (48 eyes) aged 71.01.8 years, who underwent an extended complex of ophthalmoneurostimulation, including a course of endonasal electrophoresis of vitamin B12 (for a course of 10 daily procedures), transocular infrared stimulation (for a course of 10 daily procedures), oxygen therapy with Heliox-21 breathing mixture (for a course of 10 daily procedures), and acupuncture (for a course of 10 daily procedures), and group 2 ― 25 patients (50 eyes) aged 751.1 years, who underwent a course of conservative treatment with vitamins according to existing ophthalmological standards, which served as a background in group 1. Visual acuity was assessed (visual acuity), indicators of optical coherence tomography and optical coherence tomography with angiography function of the retina, local photosensitivity, autofluorescence of the retina and bioelectric potential in pattern-electroretinography. Studies were performed before therapy, after 2 weeks, 3 months, 6 months, and 12 months, after a course of treatment. \u0000RESULTS: Visual acuity and anatomical parameters of the retina in high resolution (thickness of the central zone and the thickness of the choroid) did not change during the entire observation period. Analysis of light sensitivity showed a significant normalization of the average threshold of retinal photosensitivity when prescribing an extended complex of ophthalmoneurostimulation. \u0000CONCLUSION: Conducted extended course of physiotherapy significantly reduced the functional depression of the central visual field, coordinating with foci of retinal pigment epithelium atrophy. Most likely, this positive effect was achieved due to the activation of the level of the ganglionic and bipolar layers of the retina.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"162 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114652635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Low-level laser therapy in the supportive treatment of dermatologic adverse events in oncology","authors":"A. S. Polonskaia, E. Shatokhina, L. S. Kruglova","doi":"10.17816/rjpbr109603","DOIUrl":"https://doi.org/10.17816/rjpbr109603","url":null,"abstract":"Supportive treatment plays an important role in oncology nowadays. The main aims of oncologic supportive treatment are management of cancer symptoms and adverse events of cancer treatment. \u0000In terms of dermatologic adverse events the most important types of reaction are oral mucositis during radiation therapy, chemotherapy and during hematopoetic stem cell transplantation, palmoplantar syndrome during chemotherapy, palmoplantar skin reaction, acneiform paronychia and pyogenic granulomas during targeted therapy, immune-related dermatologic adverse events during immunotherapy. \u0000During recent years, special attention has been paid to low level laser therapy for the prophylaxis and management of cancer therapy dermatologic adverse events. The effects of low level laser therapy may have a beneficial effect on many conditions that play important roles in the pathogenesis of radiation and chemotherapy-induced complications in oncologic patients. Therapeutic effects of low level laser therapy are attributed to the stimulation of adaptive processes and to the increase of nonspecific resistance. The latter develop due to the close interaction of the immune, humoral and nervous systems. When choosing a method for the supportive treatment of cancer therapy adverse events, it is extremely important to establish safety in terms of the tumor process and absence of negative effects on cancer treatment. \u0000Effects of low level laser therapy on the proliferative and invasive activity of an existing malignancy remains a matter of debate due to conflicting results from in vitro studies. \u0000At the same time, according to the results of numerous clinical studies, the use of this method is assumed to be safe for cancer patients.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114708053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of physiotherapy on the electrical excitability of the shoulder muscles in the early postoperative period after radical surgical treatment of breast cancer","authors":"I. Evstigneeva, M. Gerasimenko, I. Esimova","doi":"10.17816/rjpbr108104","DOIUrl":"https://doi.org/10.17816/rjpbr108104","url":null,"abstract":"BACKGROUND: Combined treatment of cancer patients includes a large number of aggressive therapies that lead to a complex of functional disorders. There are no publications on the influence of physical factors on the electrical excitability of the muscles of the shoulder girdle and upper limb from the side of surgery in the early period after surgical treatment of breast cancer. \u0000AIM: To determine the physical factor that will most significantly affect the electrical excitability of the muscles of the shoulder girdle and upper limb on the side of the operation after radical surgical treatment of breast cancer. \u0000MATERIAL AND METODS: A randomized, placebo-controlled study was conducted in 100 patients in the early postoperative period (24 days after surgery) for breast cancer. All patients underwent medical rehabilitation: individual physiotherapy exercises, balance therapy, sessions with a medical psychologist, physiotherapy treatment with a monofactor. The main group included 34 patients who included an extended method of fluctuorization in the course of medical rehabilitation and additionally underwent fluctuorization of the muscles of the forearm, group 2 (comparisons, n=33) the extended method of local magnetotherapy was included in the rehabilitation program and group 3 (comparisons, n=33) in addition to rehabilitation, general magnetic therapy procedures were performed. Patients underwent a study of the excitability of the neuromuscular system on the apparatus of stimulation and electrotherapy ASEtM-01/6 \"Elesculap Med TeKo\". \u0000RESULTS: It was found that fluctuating currents turned out to be more effective in the early stages, which pathogenetically contribute to the restoration of conduction along the peripheral nerves and the activation and contractility of the muscle fiber. A delayed effect of local and general magnetic therapy on improving the contractility of the muscles of the upper limb and the conductivity of the peripheral nerve fiber was noted. \u0000CONCLUSION: The inclusion of monophysical factors in the course of standard medical treatment, a course of physical therapy, exercises on a stabiloplatform and individual psychotherapy in the early stages (on days 24) after surgery contributed to the improvement in the functioning of the upper limb and the restoration of the electrical excitability of the muscles and nerves of the operated limb.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"132 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115254283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of transcutaneous electrical nerve stimulation in the treatment of a patient with amyotrophic lateral sclerosis due to syringomyelia","authors":"M. Al-Zamil, N. Kulikova, E. Vasilieva","doi":"10.17816/rjpbr111885","DOIUrl":"https://doi.org/10.17816/rjpbr111885","url":null,"abstract":"This paper demonstrates a clinical case of the development of amyotrophic lateral sclerosis with lesions of the anterior horns of the spinal cord in the cervicothoracic region against the background of syringomyelia. \u0000The main complaints of the patient at the initial request for medical care were associated with weakness and hypotrophy of the right hand. Electrokymography revealed signs of damage to the anterior horns of the spinal cord at the C5Th1 level with a predominant lesion of the motor fibers of the right median and ulnar nerves. As a result, a diagnosis of amyotrophic lateral sclerosis was made. Magnetic resonance imaging revealed the presence of Chiari I malformation and severe syringomyelia of the cervical and thoracic calving of the spinal cord. \u0000The patient underwent surgical posterior decompression of the foramen magnum. However, the treatment was not effective with the worsening of the neurological deficit in the right hand and the spread of motor deficit and hypotrophy to the left hand. \u0000After the use of transcutaneous electrical neurostimulation of the median and ulnar nerves, there was a significant regression of motor deficit with a decrease in the severity of malnutrition without significant changes in the electromyography parameters of the median and ulnar nerves. \u0000The absence of neurological deficit in the lower extremities, with the preservation of tendon reflexes in the norm, and the absence of pathological reflexes, indicates a high plasticity of the pyramidal tracts at the level of the spinal cord. \u0000Regression of motor deficit after the use of transcutaneous electrical nerve stimulation is due to improvement in the state of altered motor units with hypertrophy of muscle fibers and acceleration of reinnervation processes.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121958555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Technology of magnetophoresis of topical nonsteroidal anti-inflammatory drugs in osteoarthritis (clinical and experimental study)","authors":"I. Osnovina, E. Vladimirtseva","doi":"10.17816/rjpbr112030","DOIUrl":"https://doi.org/10.17816/rjpbr112030","url":null,"abstract":"BACKGROUND: The high degree of evidence for the use of pharmacotherapy currently does not cause doctors to doubt, however, the use of non-pharmacological approaches in general and physical factors in particular is the subject of many years of discussion for them. One of the main places in the pharmacotherapy of osteoarthritis is occupied by nonsteroidal anti-inflammatory drugs, while our interest is associated with a group of so-called topical drugs. \u0000AIM: In order to methodically substantiate the application of the magnetophoresis technology of the topical form of nimesulide in an experimental study, the influence of the magnetic field on the spectroscopic and thixotropic characteristics of the drug was determined, and the clinical efficacy of the combined use of magnetotherapy and the transdermal form of nimesulide in comparison with the application of the drug and magnetic therapy with a pulsed low-frequency magnetic field was determined. \u0000MATERIAL AND METHODS: A randomized study involving 60 patients with osteoarthritis of the knee joints was performed. The experimental part of the study on the effect of the magnetic field on the structure and properties of the gel form of the preparation containing 1% nimesulide (chemical formula: 4'-nitro-2'-phenoxy-methane sulfonanilide) was carried out in laboratory conditions. The clinical part of the study included the use of local therapy (application of nimesulide gel in an amount of 24 g) to the skin in the knee joint area, followed by the placement of inductors of the ALMAG+ magnetic therapy apparatus on the medial and lateral surfaces of the knee joint. The impact was carried out according to the recommended \"3+1\" program. \u0000RESULTS: An analysis of the effectiveness of therapy conducted in a group of 60 patients with osteoarthritis of the knee joints showed high efficiency, expediency and safety of the use of the technology under study in the treatment of patients with joint diseases. \u0000CONCLUSION: Due to the synergistic effect on the pathogenesis of articular syndrome, the gel form of nimesulide and the magnetic field have a unidirectional effect: anti-inflammatory, decongestant, analgesic, microcirculatory. In addition, the magnetic field enhances the absorption and flow of the drug into the tissues, being a physical enhancer (amplifier), which significantly affects the result of treatment.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124318473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}