Russian Journal of Physiotherapy, Balneology and Rehabilitation最新文献

{"title":"Ways to increase the effectiveness of hypertension correction during antitumor therapy with the use of VEGF inhibitors","authors":"Т. Р. Эйнуллаева","doi":"10.17816/rjpbr628823","DOIUrl":"https://doi.org/10.17816/rjpbr628823","url":null,"abstract":"In recent years, cardioncology has rapidly become responsible for comprehensive decision-making appropriate cancer patients receiving cardiotoxic cancer therapy. Currently, the implementation of a multidisciplinary approach in the correction of adverse events using various drug antitumor therapy regimens is becoming increasingly relevant. In particular, given the widespread use of vascular-endothelial growth factor inhibitors, both at the heart of complex schemes and in mono-supportive modes. It is important to timely identify and correct such a clinically significant adverse event as an increase in blood pressure at the time of administration and in the early follow-up period. Adherence to standard drug regimens for hypertension, which usually provide satisfactory blood pressure control between cycles of administration of vascular-endothelial growth factor inhibitors, in a number of patients did not allow the same effective retention of blood pressure in the planned intervals with the administration of bevacizumab. The intensification of drug therapy for hypertension, both at the pre-infusion stage and at the time of an increase in blood pressure, was of a multidirectional nature. \u0000Search and summarize information on the availability and development of physiotherapeutic treatment methods for the correction of hypertension during antitumor therapy in cancer patients using vascular-endothelial growth factor inhibitors. 35 literature sources were analyzed. There are no data on the development of physiotherapeutic methods for the treatment of bevacizumab-induced hypertension. Domestic sources ― 25 articles. Foreign sources ― 10 articles. \u0000An analysis of the literature concluded that there is a lack of research on the development of physiotherapeutic methods for the treatment of bevacizumab-induced hypertension. In order to reduce the cardiotoxicity of humanized recombined monoclonal antibodies, maintain the dose interval period, improve survival and eliminate the need for dose adjustment of antihypertensive drugs, it is proposed to consider the use of preformed physical factors in the treatment of bevacizumab-induced hypertension.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"9 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141652597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of descriptions of therapeutic exercise procedures in the rehabilitation of patients with subacromial impingement syndrome: assessment using the Consensus on Exercise Reporting Template (CERT checklist)","authors":"A. M. Gazimiev, Z. Pilipson, E. E. Koneva, D. Ilyin, Vladislav A. Polonskii, E. Achkasov, A. V. Korolev","doi":"10.17816/rjpbr627517","DOIUrl":"https://doi.org/10.17816/rjpbr627517","url":null,"abstract":"BACKGROUND: Therapeutic exercises are the method of choice for conservative treatment of subacromial impingement syndrome. However, due to poor content reporting of exercise in clinical trials there are limitations in interpretation and replication of these trials’ methods and results. In 2016 the CERT (Consensus on Exercise Reporting Template) was developed to address this problem. \u0000AIM: To evaluate the completeness of content reporting of exercise interventions in clinical trials for patients with subacromial impingement syndrome using CERT and implement the principles of CERT into our own practice by describing an original therapeutic exercise protocol. \u0000MATERIALS AND METHODS: A search was conducted for scientific articles published from October 2016, that mentioned therapeutic exercises as a treatment method for subacromial impingement syndrome. Then, the CERT was applied to 34 selected publications, the data was analyzed and compared with similar studies. A description of an original therapeutic exercise protocol was conducted in accordance with the principles of CERT. \u0000RESULTS: The mean CERT score was 9,9 (52,17%); median 10; range 4–18; 19 (55,88%) trials had a CERT score of ≥10, while the remaining 15 (44,12%) scored 10. The most poorly reported items were description of instructor qualifications (2), individual or group (3), motivation strategies (6), progression rule (7a), adverse events (11), tailored (how) (14b), starting level rule (15), adherence (planned and actual) (16a, 16b). Only 50% of studies included data on adherence report (5). \u0000CONCLUSION: The description of therapeutic exercises for patients with subacromial impingement syndrome in published trials remains poorly reported. Proper critical analysis of studies using CERT should be taken into account when assessing the effectiveness of ongoing research investigating therapeutic gymnastics.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"33 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141655244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the effectiveness of complex medical rehabilitation of patients with polyposis rhinosinusitis associated with atopic dermatitis using ICF","authors":"T. G. Pelishenko, L. S. Kruglova, S. N. Nagornev","doi":"10.17816/rjpbr627528","DOIUrl":"https://doi.org/10.17816/rjpbr627528","url":null,"abstract":"BACKGROUND: In medical rehabilitation of patients with polyposis rhinosinusitis, aimed at solving the urgent strategic task of public health care to achieve and maintain an optimal level of functioning of persons suffering from partial disability through the development of effective methods of restoration of impaired functions and prevention of complications, there is a need to adequately assess the effectiveness of the measures taken. In this regard, it should be noted that the International Classification of Functioning, Disability and Health (ICF) serves as the gold standard for assessing the patient's quality of life and the effectiveness of rehabilitation measures. The category of human functioning acts as a system-forming basis and starting point of the patient's rehabilitation process in the ICF. In practice, the ICF is based on the biopsychosocial model of health (disease) assessment, which considers psychological and social factors of health (disease) and biological disorders in close interrelated unity. \u0000AIM: To evaluate the effectiveness of complex medical rehabilitation of patients with polyposis rhinosinusitis associated with atopic dermatitis using dynamic changes in the main domains of the ICF. \u0000MATERIALS AND METHODS: The study was performed with 89 patients with polyposis rhinosinusitis associated with atopic dermatitis. All patients were divided into 4 groups by simple fixed randomisation. The first group (control, n=22) received only basic therapy, including endonasal application of nasonex 2 doses 2 times a day, daily twice daily washing of the nasal mucosa, as well as the use of desensitising (antihistamines, topical glucocorticoids and moisturising and emollient agents) and detoxifying agents. Patients in the second group (comparison group 1, n=22) were additionally subcutaneously administered dupilumab at a dose of 300 mcg once a fortnight. In the third group (comparison group 2, n=23) against the background of dupilumab administration the combined effect of alternating magnetic field and low-intensity laser radiation of red spectrum was performed. Patients of the fourth group (the main group, n=22) received a course of phototherapy in addition to the scope of treatment of patients of the third group. The results of medical rehabilitation of patients with polyposis rhinosinusitis associated with atopic dermatitis were evaluated according to the dynamics of specialised categories of ICF, which most accurately characterise the patient's condition from the perspective of the biopsychosocial model of the disease. \u0000RESULTS: Changes in the estimated parameters of ICF at comparable initial values had different character and were determined by the scheme of medical rehabilitation. Minimal changes were recorded in the control group. The use of dupilumab was accompanied by positive dynamics of the parameters after 1 month with a significant increase in the shifts after 6 months, indicating the recovery of a number of mental and physic","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"15 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141654184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promising technologies for pre-sterilization ultrasonic cleaning of medical devices for patient safety in physiotherapy and medical rehabilitation","authors":"T. N. Zaytseva, M. Gerasimenko, I. Evstigneeva, Oksana M. Perfileva","doi":"10.17816/rjpbr627509","DOIUrl":"https://doi.org/10.17816/rjpbr627509","url":null,"abstract":"Intensive introduction of innovative technologies into practice in order to improve the effectiveness of treatment and diagnostic measures and reduce the negative impact on the human body nevertheless contributes to the emergence of adverse events directly related to the provision of medical care. In the complex of anti-epidemic measures aimed at eliminating infection in medical organisations, a major role belongs to the correct organisation and performance of pre-sterilisation cleaning of medical devices. Technologies of processing of medical devices and pre-sterilisation cleaning should be convenient and safe to use, have no damaging effect on the processed items, be highly effective and at the same time not labour-intensive. Today cleaning with the use of ultrasonic units remains promising, with the help of which the standardisation of the treatment process is carried out, the influence of the human factor on the quality of cleaning is reduced, and the control of the main critical parameters of the process is carried out in automatic mode. \u0000The purpose of the work is to justify the need to maintain the safety of the patient and staff using the promising use of ultrasonic influences. \u0000The results of this literature review reflect information about the safety and effectiveness of the method of ultrasonic pre-sterilization cleaning of medical instruments used in physiotherapy and medical rehabilitation. Basic information is provided about the physical essence of the ultrasonic cleaning process, its effect on biological systems from the standpoint of physical, biological and chemical effects, which ensures the safety of manipulations and procedures in physiotherapy and medical rehabilitation.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"53 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141654573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effectiveness of comprehensive rehabilitation of patients with fine motor impairment after ischemic stroke","authors":"Ksenya V. Lupanovа, I. Sidyakina, A. Mikhailova, N. B. Korchazhkina","doi":"10.17816/rjpbr628824","DOIUrl":"https://doi.org/10.17816/rjpbr628824","url":null,"abstract":"BACKGROUND: The consequences of acute cerebrovascular accidents significantly reduce the quality of life and disrupt the professional activity of patients. A number of studies in patients with mild and moderate paresis of the upper limb after ischemic stroke have shown the clinical effectiveness of the use of hardware technologies based on the principle of biofeedback ― a non-drug treatment method using special equipment for recording, amplification and \"feedback\" physiological information to the patient. \u0000AIM: To evaluate the effectiveness of fine motor skills restorationin patients after ischemic stroke using hardware methods with biofeedback, in combination with peripheral electrical myostimulation and basic therapy. \u0000MATERIALS AND METHODS: At the Medsi Clinical Hospital, in the personalized rehabilitation department, examinations and treatment and rehabilitation measures were carried out for 57 patients (22 women and 35 men) who had suffered ischemic stroke with motor disorders in the upper limb. Patients were randomized into groups: group 1 (comparison) ― 30 patients who underwent a standard rehabilitation program for neurological disorders, within which peripheral electrical myostimulation (ACorD) N 10 was performed daily in combination with an additional set of exercises for fine motor skills 30 minutes 5 times a week No 20; group 2 (main) ― 27 patients who along with the basic program and peripheral electromyostimulation (ACorD) N 10 daily, underwent biofeedback sessions on the HandTutor device for 30 minutes, 5 times a week No 20. The patients received drug therapy for neurological disorders, they underwent physical therapy exercises, walking treatment on the Lokomat automatic device, mechanotherapy, and sessions with a neuropsychologist. Before and after the end of rehabilitation measures, at 3, 6 and 12 months, the patient’s condition was assessed using the Rivermead Activities of Daily Living scale ― part \"hand\", the state of hand function was assessed using the \"Finger and Wrist Movement Analysis\" test on the HandTutor glove (MediTouch, Israel). \u0000RESULTS: It has been established that the inclusion of the proposed method in a complex of rehabilitation measures after a stroke contributes to a statistically significant positive dynamics of Rivermead scale indicators (part \"hand\") and an active increase in the movements of all fingers and wrists by 30–40% within 3–12 months after the start of rehabilitation events. \u0000CONCLUSION: The use of hardware methods with biofeedback is a clinically effective approach within the framework of complex rehabilitation of post-stroke patients with impaired function of the upper limb, the positive effect of which is based on the mechanisms of neuroplasticity.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141652796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the quality of life in complex medical rehabilitation of patients at the stage of chemoradiotherapy for head and neck cancer","authors":"V. Kozyreva, O. Yarustovskaya","doi":"10.17816/rjpbr631795","DOIUrl":"https://doi.org/10.17816/rjpbr631795","url":null,"abstract":"BACKGROUND: At the stage of chemoradiotherapy of malignant neoplasms of the head and neck, in 90% of cases, the development of radiation dermatitis and mucositis is observed. The resulting acute radiation reactions negatively affect not only the quality of life of the patient, but also the planned treatment. A multidisciplinary approach with the inclusion of basic treatment, physical therapy, physical factors, psychological correction, and nutritional support is an effective strategy for improving the patient's quality of life at this stage of treatment. \u0000AIM: To assess the quality of life of patients in complex medical rehabilitation who underwent chemoradiotherapy for malignant neoplasms of the head and neck. \u0000MATERIALS AND METHODS: An interventional prospective randomized study was conducted with the participation of 60 patients with malignant neoplasms of the oral cavity, larynx, oropharynx, larynx undergoing chemoradiotherapy. The main group (n=30) received a course of medical rehabilitation: exposure to low-temperature argon plasma, general magnetic therapy, physical therapy, training on the support reaction on a barefoot platform, nutritional support and classes with a medical psychologist. In patients of the comparison group (n=30), plasma exposure was not included in the rehabilitation course. The effect of chemoradiotherapy for head and neck cancer on the patient's quality of life was assessed by the severity of pain syndrome, physical functioning, and limitations of daily activities using Visual Analogue Scale (VAS), Hospital Anxiety and Depression Scale (HADS) techniques, a questionnaire developed by C.D. Spielberger and adapted by Y.L. Khanin, the SF-36 questionnaire. \u0000RESULTS: After a course of chemoradiotherapy, patients began to complain of pain, burning in the mouth, complaints of dry mouth, pain when swallowing, eating, limited mouth opening, redness and peeling of the skin, voice changes, difficulty falling asleep, frequent awakenings at night, embarrassment of one’s appearance. In patients of both groups, there was a decrease in the level of reactive and personal anxiety, the increased level of anxiety and depression decreased by the end of the course of chemoradiotherapy with a decrease in indicators after 6 months. Despite the increase in pain intensity during chemoradiation treatment, an increase in vital activity indicator was recorded, as well as an indicator of self-assessment of one’s health by the end of the course of chemoradiation treatment. \u0000CONCLUSION: The resulting radiation mucositis and epidermitis at the stage of chemoradiotherapy for head and neck cancer lead to physical and psychological limitations, worsening the patient's quality of life, which determines the need to accompany this stage of treatment with comprehensive medical rehabilitation. The study of the dynamics of the parameters of the quality of life of patients is the basis for the selection of individual rehabilitation treatment programs.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"8 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141653662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An algorithm for the use of various transcutaneous electrical nerve stimulation modalities in treatment of patients with residual positive sensory symptoms after surgical decompression of the carpal tunnel","authors":"M. Al-Zamil, R. Kuliev, E. Vasilieva, A. Mikhailova, K. Kotenko","doi":"10.17816/rjpbr627453","DOIUrl":"https://doi.org/10.17816/rjpbr627453","url":null,"abstract":"BACKGROUND: The main cause of residual neurological symptoms after surgical carpal tunnel decompression is long-term compressive neuropathy of the median nerve in the carpal tunnel in the preoperative period. As a result, irreversible morphological and neurophysiological changes gradually develop on the part of the compressed median nerve, which may not recover after its decompression. \u0000AIM: To establish an algorithm for the use of transcutaneous electrical nerve stimulation (TENS) of various modalities in the treatment of patients with residual neurological symptoms after undergoing surgical carpal tunnel decompression. \u0000MATERIALS AND METHODS: We observed 100 patients with residual positive symptoms after undergoing successful of surgical decompression of the carpal tunnel. The control group consisted of 20 patients (10 women and 10 men) and underwent a 2-month course of standard drug therapy. The main group (n=80), in addition to the standard drug therapy carried out in the control group, underwent a course of TENS, which began on the 2nd month of drug treatment. Depending on the form of TENS therapy, patients of the main group were divided into 4 subgroups: the TENS placebo subgroup (n=20) underwent a course of ineffective TENS. High-frequency TENS subgroup (n=20) completed a course of high-frequency low-amplitude TENS. Low-frequency TENS subgroup (n=20) completed a course of low-frequency high-amplitude TENS. The high-frequency TENS + low-frequency TENS subgroup underwent a simultaneous course of high-frequency TENS and low-frequency TENS (n=20). Positive sensory symptoms of numbness, tingling, burning and a feeling of electric charge were rated by the patients themselves over the past 24 hours on a 10-point scale. \u0000RESULTS: When comparing the subgroups of effective TENS (high-frequency TENS, low-frequency TENS, high-frequency TENS + low-frequency TENS) with the subgroup of ineffective TENS (placebo), a significant decrease in positive sensory symptoms was revealed in the subgroups of high-frequency TENS, low-frequency TENS, high-frequency TENS and low-frequency TENS by 112%, 40% and 163% respectively. When comparing the effectiveness of high-frequency TENS and low-frequency TENS with each other, it was possible to establish that high-frequency TENS exceeds the efficiency of low-frequency TENS by almost 2 times. However, the combination of low-frequency TENS with high-frequency TENS enhances the therapeutic effect of the latter by 46%. \u0000CONCLUSION: The use of high-frequency TENS is recommended in the treatment of patients with residual positive sensory symptoms. For strong positive sensory symptoms with the development of secondary affective reactions, it is recommended to combine high-frequency TENS and low-frequency TENS to enhance the effect.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141653944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"About the benefits of physical therapy during antitumor therapy in patients with non-small cell lung cancer","authors":"A. E. Kashanova, E. E. Koneva, Anastasiya S. Mochalova","doi":"10.17816/rjpbr627512","DOIUrl":"https://doi.org/10.17816/rjpbr627512","url":null,"abstract":"BACKGROUND: The data available today show the positive impact of increased physical activity on the patient’s condition, helping not only to improve physical health, but also psycho-emotional state, reducing stress and anxiety. Comprehensive rehabilitation programs can significantly improve the overall well-being of cancer patients and contribute to their return to an active social life. \u0000AIM: To study the effect of increased physical activity in the form of physical therapy on the overall result of antitumor treatment, the level of quality of life of patients with non-small cell lung cancer receiving immunotherapy both alone and in combination with cytostatics. \u0000MATERIALS AND METHODS: The study involved 56 patients who were divided into two groups: main (n=30) and control (n=26). The study included patients with ECOG status 1–3. In both groups, patients received standard antitumor therapy ― immunotherapy with pembrolizumab 400 mg every 42 days or 200 mg every 21 days as monotherapy, or in combination with cytotoxic therapy (carboplatin plus paclitaxel or pemetrexed). In addition to drug treatment, patients from the main group also regularly engaged in therapeutic exercises with an instructor. \u0000RESULTS: From the presented data and visualization it is clear that after treatment with the addition of physical education, the average level of quality of life in patients increased, the results highlight the significant positive impact of the rehabilitation program on the quality of life of cancer patients, reducing stress levels and improving functional indicators. \u0000CONCLUSION: The study shows that regular practice of therapeutic exercises can improve stress levels and improve emotional well-being, help reduce fatigue and reduce general weakness. A reduction in symptoms of depression and anxiety has been clearly demonstrated. Exercise therapy leads to increased muscle strength, which is especially important for recovery from intensive cancer treatments.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"48 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141654825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamics of oxidative stress markers and cytokine content in patients with peri-implantitis at complex application of mesodiencephalic modulation and ozone therapy","authors":"Madina R. Balayeva, S. Nagornev, A. Remizova","doi":"10.17816/rjpbr627063","DOIUrl":"https://doi.org/10.17816/rjpbr627063","url":null,"abstract":"BACKGROUND: Significant prevalence of inflammatory complications after dental implantation determines the necessity to search for a more effective solution of this problem with the formation of a comprehensive program of prevention and treatment of peri-implant diseases and its integration into the modern concept of dental rehabilitation. \u0000AIM: Study of oxidative stress patterns, level of pro- and anti-inflammatory cytokines in patients with peri-implantitis during complex therapy using mesodiencephalic modulation, ozone therapy and their combination. \u0000MATERIALS AND METHODS: The study was carried out with participation of 116 patients with peri-implantitis of I and II classes according to S.A. Jovanovic. By means of simple fixed randomization (based on random numbers generation by computer program) all patients were divided into 4 groups. The first group (control group, n=28) received standard dental therapy, including professional oral hygiene and local application of antiseptic agents. In the second group (comparison group 1, n=29) in addition to the standard therapy the course ozone therapy was carried out, for which the peri-implant zone was irrigated with ozonized physiological solution with ozone concentration 2.5–5.5 mcg/ml for 15 min. In the third group (comparison group 2, n=30) the standard treatment was supplemented with the course application of mesodiencephalic modulation. Patients of the fourth group (main group, n=29) along with the standard treatment received complex treatment including course application of ozone therapy and mesodiencephalic modulation. The results were evaluated after the end of therapy by the dynamics of oxidative stress markers and the content of pro- and anti-inflammatory cytokines. The assessment of clinical efficacy in randomized groups was based on the determination of oral hygiene indexes, papilla bleeding and papillo-marginal-alveolar index, as well as the implant stability coefficient. \u0000RESULTS: The use of different therapy schemes caused changes in the patterns of peroxidation metabolism and cytokine status, the intensity of which had different character. In the least degree the corrective activity was revealed in the control group of patients. Supplementation of standard treatment with therapeutic physical factors was accompanied by more pronounced dynamics of the estimated parameters, the direction of which indicated normalization of the lipoperoxidation system and cytokine mechanism of inflammation. Maximum changes of the estimated parameters were revealed in the main group, where the standard therapy was supplemented with a course complex application of mesodiencephalic modulation and ozone therapy. This was manifested in the strengthening of antioxidant activity of enzymes and reduction of the level of lipoperoxidation products to the level of the healthy group, as well as regression of the level of proinflammatory factors against the background of an increase in the level of mediator with anti-in","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"46 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140978990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of physiotherapeutic methods in the treatment of dry eye syndrome","authors":"Agata G. Egiazarova, A. K. Raifeld, N. Korchazhkina","doi":"10.17816/rjpbr627392","DOIUrl":"https://doi.org/10.17816/rjpbr627392","url":null,"abstract":"The relevance of the treatment of dry eye syndrome is associated with the widespread prevalence of this disease. Along with the development of information technology and an increase in time spent in front of screens, the number of people suffering from this disease is steadily growing. \u0000The basis of treatment for dry eye syndrome is the use of “artificial tears” preparations, which are instilled into the conjunctival cavity to replenish moisture deficiency. But the effect of tear replacement therapy in case of dysfunction of the meibomian glands does not last long. In this regard, the use of physiotherapeutic methods for treating dry eye syndrome to prolong the effect of drug therapy for this pathology is of particular importance. \u0000Each of the methods of physiotherapeutic treatment of dry eye syndrome has its own unique mechanisms of action and indications for use. Physiotherapeutic methods are an effective tool in the treatment of dry eye syndrome, providing the opportunity to improve the quality of life of patients suffering from this common ophthalmic disease.","PeriodicalId":226051,"journal":{"name":"Russian Journal of Physiotherapy, Balneology and Rehabilitation","volume":"34 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140979706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}