The Japanese journal of experimental medicine最新文献_第9页

Experimental urolithiasis in the bladder of rats. 实验性大鼠膀胱尿石症。

The Japanese journal of experimental medicine Pub Date : 1988-12-01

S Takahashi, K Okada, L Lelkes, T Shimamura

引用次数: 0

Laboratory strains of hamster, gerbil and mastomys maintained at the Institute of Medical Science, University of Tokyo. 东京大学医学研究所保存的仓鼠、沙鼠和乳突鼠的实验室菌株。

The Japanese journal of experimental medicine Pub Date : 1988-12-01

S Tanaka, M Nozaki, T Maruyamauchi, T Kaneko, K Yamanouchi, M Okugi, A Matsuzawa

引用次数: 0

Some factors affecting isolation of Clostridium tetani from human and animal stools. 影响从人畜粪便中分离破伤风梭菌的一些因素。

The Japanese journal of experimental medicine Pub Date : 1988-12-01

I Ebisawa, M Takayanagi, M Kigawa

引用次数: 0

Litomosoides carinii in rodents: immunomodulation in potentiating action of diethylcarbamazine. 啮齿类动物:二乙基卡马嗪增强作用的免疫调节。

The Japanese journal of experimental medicine Pub Date : 1988-12-01

R K Chatterjee, N Fatma, R K Jain, C M Gupta, N Anand

引用次数: 0

Generation of self-macrophage-toxic non-T cells in the MHC-homozygous F1 spleen cells co-cultured with parental cells: possible involvements of host cells in impaired immunity in GVH disease. 与亲代细胞共培养的mhc纯合子F1脾细胞中自身巨噬细胞毒性非t细胞的产生:宿主细胞在GVH疾病中免疫受损的可能参与

The Japanese journal of experimental medicine Pub Date : 1988-12-01

M Hosono, T Hosokawa, M Fujiwara, Y Katsura

{"title":"Generation of self-macrophage-toxic non-T cells in the MHC-homozygous F1 spleen cells co-cultured with parental cells: possible involvements of host cells in impaired immunity in GVH disease.","authors":"M Hosono, T Hosokawa, M Fujiwara, Y Katsura","doi":"","DOIUrl":"","url":null,"abstract":"Simplified-in vitro system was developed to examine the contribution of host's cells in graft-versus-host (GVH)-disease-associated immunodeficiencies. In analogy with major histocompatibility complex (MHC)-matched GVH-reaction, (BALB/c x DBA/2)F1 (H-2d) hybrid spleen cells were co-cultured with irradiated BALB/c (H-2d) spleen cells, so that cellular activities to be generated are ascribable to F1 cells. In vitro development of anti-allo-specific cytotoxic T cells of the F1 origin was dramatically suppressed by coexistence of the irradiated parental cells and by the addition of F1 cells precultured once with the parental cells, suggesting the generation of suppressor cells in the F1 (host) cells activated by the parental cells. Thus generated suppressor cells are Thy.1-, weakly or nonadherent and radiosensitive. Interestingly, in the same reactions there also developed Thy.1- cytotoxic cells for autologous macrophage targets. An involvement in immunodeficiencies in GVH disease of the host-derived cytotoxic and/or immunosuppressive, non-T cells was discussed.","PeriodicalId":22530,"journal":{"name":"The Japanese journal of experimental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14113607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antagonists of mouse paw oedema induced by Habu snake (Trimeresurus flavoviridis) venom. Inhibitions by various antagonists administered alone or in combinations. 哈布蛇毒致小鼠足跖水肿拮抗剂的研究。各种拮抗剂单独或联合使用的抑制作用。

The Japanese journal of experimental medicine Pub Date : 1988-12-01

J Detrait, J Jacob

{"title":"Antagonists of mouse paw oedema induced by Habu snake (Trimeresurus flavoviridis) venom. Inhibitions by various antagonists administered alone or in combinations.","authors":"J Detrait, J Jacob","doi":"","DOIUrl":"","url":null,"abstract":"When injected into the sole of the hind paw of mice, Habu snake (Trimeresurus flavoviridis) venom produced a prolonged oedema (72 hours). When administered alone, most of the studied drugs (mepyramine, methysergide, cyproheptadine, indomethacin, aspirin, dexamethasone and aprotinin) inhibited this oedema only partially and transiently (less than 7 hours). Some drugs however (EDTA, Biogel P4, zymosan and celluloses) were able to abolish it progressively. Combinations of some of these drugs resulted in various synergisms; in particular important and prolonged inhibitions were observed with aprotinin-dexamethasone, one of these drugs and EDTA, and especially EDTA-zymosan, which abolished totally the oedema from 2 hours after the injection of the venom to its end (72 hours). Antagonisms between components of combinations were also observed. The mechanisms of these synergisms and antagonisms are discussed. In particular, it is suggested that the blockade of the two pathways \"classical\" and \"alternative\", of the complement by EDTA and zymosan respectively might account for their important and early synergism. Antagonisms also helped in indicating some mechanisms of action.","PeriodicalId":22530,"journal":{"name":"The Japanese journal of experimental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14382770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

11-Deoxycorticosterone-induced hypertension, glomerulosclerosis and renal arterial and arteriolar lesions. 11-脱氧皮质酮引起的高血压、肾小球硬化和肾动脉、小动脉病变。

The Japanese journal of experimental medicine Pub Date : 1988-10-01

T Shimamura

引用次数: 0

Protection against the lethal effects of whole body vibration by the alpha-adrenergic system in rat. 肾上腺素能系统对大鼠全身振动致死性的保护作用。

The Japanese journal of experimental medicine Pub Date : 1988-10-01

R Inaba, A Okada

引用次数: 0

The organ distribution of [3H]endotoxin following partial hepatectomy. 肝部分切除术后[3H]内毒素的器官分布。

The Japanese journal of experimental medicine Pub Date : 1988-10-01

M Shirai, J Shiga, G Yoshimura, I Fukuda, S Kanegasaki, W Mori

引用次数: 0

Application of a micro enzyme-linked immunosorbent assay (ELISA) to detection of anti-amebic antibody in various forms of amebic infection. 应用微酶联免疫吸附试验(ELISA)检测各种形式阿米巴感染的抗阿米巴抗体。

The Japanese journal of experimental medicine Pub Date : 1988-10-01

T Takeuchi, H Matsuda, E Okuzawa, T Nozaki, S Kobayashi, H Tanaka

{"title":"Application of a micro enzyme-linked immunosorbent assay (ELISA) to detection of anti-amebic antibody in various forms of amebic infection.","authors":"T Takeuchi, H Matsuda, E Okuzawa, T Nozaki, S Kobayashi, H Tanaka","doi":"","DOIUrl":"","url":null,"abstract":"Techniques of a micro enzyme-linked immunosorbent assay (ELISA) used for the serodiagnosis of schistosomiasis were applied to amebic infection. Test sera were divided primary on the basis of serologic diagnosis and stool examination as follows; (I) gel diffusion precipitin test (GDP) positive and stool examination positive: 9 specimens, (II) GDP positive and stool examination negative: 29 specimens, (III) GDP negative and stool examination positive: 32 specimens. Virtually all of the individuals belonging to (III) were asymptomatic, while more than 75% of (I) and (II) were symptomatic. The upper limit of 99% critical range was calculated from the data of 70 serum specimens from healthy adult Japanese and was employed as the cut-off value. All of the specimens of (I) and (II) were judged positive by ELISA, generally with a much higher absorbance than the cut-off value; whereas, approximately 80% of (III) were judged positive. The average absorbance of (III) was lower than that of (I) and (II). These findings suggest that the ELISA is well in accord with GDP qualitatively as far as GDP-positive individuals are concerned, and that even asymptomatic cyst carriers with negative serology by GDP may often be producing anti-amebic antibodies, although the titers are low.","PeriodicalId":22530,"journal":{"name":"The Japanese journal of experimental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1988-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14044832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0