The Internet Journal of Pharmacology最新文献_第9页

Deep Brain Stimulation : Surgical Treatment For Parkinson’s Disease 脑深部刺激:帕金森病的外科治疗

The Internet Journal of Pharmacology Pub Date : 2008-12-31 DOI: 10.5580/16ba

Y. M. Joshi, G. H. Gunjal, P. Kaldhone, V. Kadam

引用次数: 0

Caffeine Abstinence During The Menstrual Cycle:An Evaluation Of Mood, Somatic, Cognitive, And Psychomotor Effects Of Withdrawal 月经周期中的咖啡因戒断:戒断对情绪、躯体、认知和精神运动影响的评估

The Internet Journal of Pharmacology Pub Date : 2008-01-01 DOI: 10.5580/60c

H. Vo

{"title":"Caffeine Abstinence During The Menstrual Cycle:An Evaluation Of Mood, Somatic, Cognitive, And Psychomotor Effects Of Withdrawal","authors":"H. Vo","doi":"10.5580/60c","DOIUrl":"https://doi.org/10.5580/60c","url":null,"abstract":"Women frequently report the occurrence of various symptoms that occur during the phases of the menstrual cycle. The factors affecting this symptomatology are not yet fully understood, but there is reason to believe that one widely consumed drug, caffeine, may impact these symptoms. In the present study, the effects of caffeine withdrawal across the menstrual cycle on several aspects of menstrual symptomatology and cognitive function were assessed in healthy young women. A repeatedmeasures design, examining caffeine intake and withdrawal symtomatology in 48 college age women used daily diaries of caffeine intake, premenstrual symptoms, and caffeine withdrawal effects, and each participant also did a daily LH surge test. In the laboratory, computerized cognitive tasks were administered in order to assess the cognitive effects of caffeine abstinence during the follicular and luteal phases of the menstrual cycle. Data analyses focused on withdrawal symptom ratings and performance on the cognitive tests one day during the follicular phase and one day during the luteal phase of the cycle after 24 hours of caffeine abstinence. Caffeine withdrawal significantly impacted self-report symptom ratings during select days of abstinence, as compared with days of non-abstinence, during both follicular and luteal phases. Withdrawal did not, however, impact cognitive performance across the menstrual cycle.","PeriodicalId":22523,"journal":{"name":"The Internet Journal of Pharmacology","volume":"21 12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77328660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Tryptophan Adjunctive Therapy To Conventional Haloperidol Treatment In Schizophrenia: Effects On Serotonergic Mechanisms In Rat Brain 色氨酸辅助治疗常规氟哌啶醇治疗精神分裂症:对大鼠脑中血清素能机制的影响

The Internet Journal of Pharmacology Pub Date : 2007-12-31 DOI: 10.5580/14d2

F. Batool, D. Haleem

引用次数: 0

Buspirone And Anxiety Disorders: A Review With Pharmacological And Clinical Perspectives 丁螺环酮与焦虑症:从药理学和临床角度综述

The Internet Journal of Pharmacology Pub Date : 2007-12-31 DOI: 10.5580/2488

F. Batool

引用次数: 8

Antioxidant Potential of galls of Quercus infectoria 栓皮栎瘿的抗氧化潜能

The Internet Journal of Pharmacology Pub Date : 2007-12-31 DOI: 10.5580/cd7

S. Umachigi, K. Jayaveera, K. Ashok, G. Kumar

{"title":"Antioxidant Potential of galls of Quercus infectoria","authors":"S. Umachigi, K. Jayaveera, K. Ashok, G. Kumar","doi":"10.5580/cd7","DOIUrl":"https://doi.org/10.5580/cd7","url":null,"abstract":"Nowadays, the fact of harmful effect of reactive oxygen species on human health is well-known. The capability of natural defense systems of living organisms against excess production of these species decreases when influenced with negative environmental factors or aging. As a result, different cellular and extracellular components, and especially nucleic acids, are damaged, causing or enhancing a number of degenerative diseases. Therefore, antioxidants that scavenge free radicals are of great value in preventing such “oxidative” pathologies. That is why natural products with antioxidant properties become more and more popular all over the world. Natural phenolic phytochemicals in fruits and vegetables have been receiving increased interest from consumers and researchers for their beneficial health effects on coronary heart diseases and cancers mainly due to their antioxidant activity. 1 As plants produce a lot of antioxidants to control the oxidative stress caused by sunbeams and oxygen, they can represent a source of new compounds with antioxidant activity. Among natural antioxidants, phenolic antioxidants are in the forefront since all the phenolic classes (simple phenolics, phenolic acids, anthocyanins, hydroxycinnamic acid derivatives, and flavonoids) have the structural requirements of free radical scavengers and antioxidants 2","PeriodicalId":22523,"journal":{"name":"The Internet Journal of Pharmacology","volume":"216 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2007-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76900854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Antigenotoxic effect of apigenin on chromosomal damage induced by cyproterone acetate in human lymphocytes 芹菜素对醋酸环丙孕酮致人淋巴细胞染色体损伤的抗基因毒性作用

The Internet Journal of Pharmacology Pub Date : 2007-12-31 DOI: 10.5580/242e

Y. Siddique, M. Afzal

引用次数: 0

Phytochemical and pharmacological activity of Aegle marmelos as a potential medicinal plant: An overview 蜜瓜作为潜在药用植物的植物化学和药理活性综述

The Internet Journal of Pharmacology Pub Date : 2007-12-31 DOI: 10.5580/bd

R. Chanda, Amitava Ghosh, Tutun Mitra, J. P. Mohanty, N. Bhuyan, Ganesh Pawankar

引用次数: 21

Dissolved Oxygen concentration analysis of L-Lysine Fermentation Production by Corynebacterium glutamicum 谷氨酸棒状杆菌发酵生产l -赖氨酸的溶解氧浓度分析

The Internet Journal of Pharmacology Pub Date : 2007-12-31 DOI: 10.5580/19f0

D. Rao, S. A. Razak, B. Praveena, A. Swamy

引用次数: 0

Anxiolytic Activity Of Seed Extract Of Caesalpinia Bonducella (Roxb) In Laboratory Animals 山参种子提取物对实验动物的抗焦虑活性研究

The Internet Journal of Pharmacology Pub Date : 2007-12-31 DOI: 10.5580/2438

Altaf Ali, N. Rao, Md. Shalam, T. Gouda, J. Babu, S. Shantakumar

{"title":"Anxiolytic Activity Of Seed Extract Of Caesalpinia Bonducella (Roxb) In Laboratory Animals","authors":"Altaf Ali, N. Rao, Md. Shalam, T. Gouda, J. Babu, S. Shantakumar","doi":"10.5580/2438","DOIUrl":"https://doi.org/10.5580/2438","url":null,"abstract":"In the traditional system of Indian medicine C.bonducella is widely used for its antipyretic, antiperiodic, anticonvulsant and antiparalytic activities. The present study was aimed to explore the anxiolytic activities of seed extract of C.bonducella in experimental animals, mice and rats. In Stair-case model, all the three doses i-e low, medium and high 400, 600 and 800mg/kg of PECB had showed a significant and dose dependent Anxiolytic activity by increasing the number of steps climbed, without any significant effect on rearings by all these three doses. Similarly in EPM model medium and high doses, but not the low dose of PECB had significantly enhanced both number of entries and time spent in open arms and decreased in number of entries and time spent in closed arms. In Hole- board model, medium and high doses 600 and 800mg/kg but not the low dose 400mg/kg of PECB had significantly enhanced the number, latency and the duration of head dipping but not the rearings. However in LDT model high doses 800mg/kg of PECB had significantly exhibited anxiolytic activity by increasing time spent, number of crossings in light compartment and decreased the time spent in dark compartment and decreased the number of rearings in both light and dark compartments. In OFT models, medium and high doses 600 and 800mg/kg but not the low dose 400mg/kg of PECB had significantly enhanced total locomotion, central locomotion, number of grooming but the immobility time has drastically reduced. All doses of PECB have not exerted any significant effect with rearing, defecation and urination. Moreover in Mirror-chamber model of anxiety, both medium and high doses 600 and 800mg/kg but not the low dose 400mg/kg of PECB had significantly reduced the time latency to enter in to the mirror chamber and increased the number of entries and time spent in the chamber. Thus the result recorded with above experimental models confirms the anxiolytic activity of PECB.","PeriodicalId":22523,"journal":{"name":"The Internet Journal of Pharmacology","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2007-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83909591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 41

The effect of pretreatment with plant extract, nicotine and caffeine on sleeping time induced by pentobarbitone in mice 植物提取物、尼古丁和咖啡因预处理对戊巴比酮诱导小鼠睡眠时间的影响

The Internet Journal of Pharmacology Pub Date : 2007-12-31 DOI: 10.5580/138b

N. Robson., A. M. Mustafa

引用次数: 0