Evidence Based Womenʼs Health Journal最新文献

{"title":"Hysteroscopy as a diagnostic tool in women with recurrent pregnancy loss, a prospective randomized controlled study","authors":"Attia Mohammed, Kamal Rageh, Amr Habib, A. Shaaban, Mohamed Rushdy","doi":"10.21608/EBWHJ.2021.66147.1129","DOIUrl":"https://doi.org/10.21608/EBWHJ.2021.66147.1129","url":null,"abstract":"","PeriodicalId":224226,"journal":{"name":"Evidence Based Womenʼs Health Journal","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121113094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Soluble Endoglin Versus Serum Placental Growth Factor for Early Prediction of Preeclampsia","authors":"Ali Bendary, M. Elgazzar, L. Mohamed","doi":"10.21608/EBWHJ.2021.74864.1134","DOIUrl":"https://doi.org/10.21608/EBWHJ.2021.74864.1134","url":null,"abstract":"Aim: Evaluation of the predictive ability of serum soluble endoglin (sEng) and placental growth factor (PLGF) levels estimated at the 12th gestational week (GW) for discrimination of women liable to develop preeclampsia (PE).Materials and Methods: 102 PE women were diagnosed according to the American Society of Hypertension and categorized according to guidelines of American College of Obstetricians and Gynecologists. The severity of PE was judged by the difference between blood pressure (ΔBP) measures at time of PE diagnosis and at time of enrolment. Blood samples were obtained at the 12th GW for ELISA estimation of serum sEng and PLGF. Study outcomes included the predictive ability of these markers for development of PE and the relation between age, body mass index (BMI) and serum levels of studied biomarkers and ΔSBP and ΔDBP.Results: 29 and 73 women developed early- and late-onset PE, respectively and 18 women had severe, while 84 women had mild PE. At time of PE diagnosis, BP measures were increased significantly in PE women in comparison to enrolment measures and to control measures. Serum levels of sEng were significantly higher, while serum PLGF levels were significantly lower in PE women than in controls. Development of PE was positively correlated with serum sEng, while was negatively correlated with serum PLGF levels. Also, there was positive significant correlation between ΔBP and BMI and serum levels of sEng, and negative significant correlation with at enrolment BP and serum levels of PLGF. ROC curve analysis defined ΔSBP and ΔDBP by 33 and 10 mmHg as a cutoff point for diagnosis of PE and defined high serum sEng as the significant sensitive predictor for development of PE at both cutoff points.Conclusion: At 12th GW, estimated levels of sEng and PLGF could discriminate pregnant women vulnerable for development of PE. Statistical analyses defined high serum sEng levels estimated at the 12th GW as the significant early predictor for upcoming PE. Maternal obesity and old age are also related to PE severity and must be considered for prediction.","PeriodicalId":224226,"journal":{"name":"Evidence Based Womenʼs Health Journal","volume":"142 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113977651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New ultrasound signs for prediction of early placental Insufficiency","authors":"T. Said, Y. El-Kassar, Gehan Shehata","doi":"10.21608/EBWHJ.2021.75491.1135","DOIUrl":"https://doi.org/10.21608/EBWHJ.2021.75491.1135","url":null,"abstract":"Background: Chronic placental insufficiency is a common condition that affects fetal growth and wellbeing. The response of the fetus to such stress depends on time and degree of placental affection. The acute placental insufficiency rapidly affects the fetal movements, amount of liquor and might lead to fetal demise while the chronic placental insufficiency is more deciduous and affects fetal weight and develops fetal growth restriction more slowly. The prophylaxis against the development of chronic placental insufficiency is more effective to protect growth and avoid perinatal morbidities and moralities.Aim: Evaluation of 2 new ultrasound signs (tent like placenta and turbid liquor) to predict early placental insufficiencyMaterials and Methods: One hundred pregnant women with gestational age between 16 weeks till 28 weeks were included in the study. This cohort of women with singleton pregnancy was evaluated by detailed ultrasound scanning to document gestational age, amniotic fluid index, cerebroplacental ratio (CPR), exclusion of congenital anomalies and other routine ultrasound scanning items. This cohort was divided into two groups, group one was the group with placental tenting and/or turbid liquor while group two was the group with no evidence of placental tenting or turbid liquor.Results: Documentation of all relevant demographic data was done. The follow up was done every two weeks in all cases unless patients complained of decreased or absent fetal movement, passage of liquor, passage of blood. Spontaneous labour was allowed in primigravidae and elective cesarean section in Cases with previous c-section at completed 38 weeks of gestation was done unless one or more of the following signs had appeared that indicated the need for emergency delivery which were : abnormal low CPR less than 0.76, severe oligohydramnios, biophysical profile equal to or less than 4/8, abnormal cardiotocogram and fetal distress. The duration from the beginning of the study and documentation of the new studied signs in the placenta and turbid liquor till the development of placental insufficiency was calculated in weeks. All complications or adverse events were documented in both groups.Conclusions: Both new signs were associated with increased risk for development of chronic placental insufficiency and can be used as predictors for evaluation of all pregnant women in the second trimester.","PeriodicalId":224226,"journal":{"name":"Evidence Based Womenʼs Health Journal","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123910078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cervical cerclage for Pregnant Women at High-risk of Recurrent Preterm Birth can act beyond its Mechanical Action","authors":"W. Amer, Ali A. Morsi, Hamasat A Alnoury","doi":"10.21608/EBWHJ.2021.75518.1136","DOIUrl":"https://doi.org/10.21608/EBWHJ.2021.75518.1136","url":null,"abstract":"Aim: Evaluation of predictive value of levels of cervicovaginal fluid (CVF) interleukin (IL)-6 and 8, and matrix metalloproteinases (MMP) estimated at time of performing cervical cerclage (CC) in women with history of spontaneous preterm birth (SPTB) for pregnancy duration.Materials and Methods: 59 women had history of SPTB (Study group) and 25 women with no history of SPTB (Control group). Two CVF samples were obtained for ELISA estimation of IL-6, IL-8, MMP8 and MMP9 levels at 14-18 gestational weeks (GW), S1 sampling time, and at time of removal of CC suture, S2 sampling time. CC was applied 4-days after S1 sampling.Results: S1-CVF levels were significantly higher in study versus control women. S2-CVF levels were significantly higher in control, while were significantly lower in study women compared to S1 levels. S2-CVF IL-6 and IL-8 levels were non-significantly higher, while levels of MMP were significantly lower in study than control women. Percentages of change in cytokines' levels showed significant differences between study and control groups. Nineteen study women had PTD at 37 GW. Study women had significantly shorter CL and pregnancy duration compared to control women. Pregnancy duration was negatively correlated with percentage of CL change, while positively correlated with percentage of decrease of cytokines levels.Conclusion: CC induced significant decrease of CVF cytokines' levels and allowed prolongation of pregnancy duration for >37 GW in 67.8% of studied women at high risk of SPTB","PeriodicalId":224226,"journal":{"name":"Evidence Based Womenʼs Health Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123733931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of Preoperative Intravenous Tranexamic Acid to Reduce Blood Loss During and After Elective Lower‐Segment Cesarean Delivery","authors":"Dalia Nour, Tarek El Husseiny, N. Osman","doi":"10.21608/EBWHJ.2021.74846.1133","DOIUrl":"https://doi.org/10.21608/EBWHJ.2021.74846.1133","url":null,"abstract":"Aim: This work aimed to study the efficacy and safety of preoperative intravenous tranexamic acid to reduce blood loss during and after elective lower‐segment cesarean delivery.Materials and Methods: A double‐blind, randomized placebo‐controlled study was undertaken of women undergoing elective lower‐segment cesarean delivery of a full‐term singleton pregnancy at a center in tertiary referral hospital , Egypt, between December, 2019 and March, 2020. Patients were randomly assigned (1:1) using computer‐generated random numbers to receive either 1 g tranexamic acid(TXA) or 5% glucose 15 minutes before surgery. Preoperative and postoperative complete blood count, hematocrit values, and maternal weight were used to calculate the estimated blood loss (EBL) during cesarean section, which was the primary outcome. Analyses included women who received their assigned treatment, whose surgery was 90 minutes or less, and who completed follow‐up.Results: Eighty women in each group.There was no statistical difference found between women subjected to TXA and those subjected to placebo regarding maternal age, weight, gestational age or mode of previous delivery. Mean EBL was significantly higher in the placebo group (896.81 ± 519.6mL mL) than in the tranexamic acid group (583.23 ± 379.62mL; P < 0.001).Conclusion: Preoperative administration of tranexamic acid safely reduces blood loss during elective lower‐segment cesarean delivery","PeriodicalId":224226,"journal":{"name":"Evidence Based Womenʼs Health Journal","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125386602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between vitamin D level and Endometriosis","authors":"A. Okasha","doi":"10.21608/EBWHJ.2019.16346.1018","DOIUrl":"https://doi.org/10.21608/EBWHJ.2019.16346.1018","url":null,"abstract":"","PeriodicalId":224226,"journal":{"name":"Evidence Based Womenʼs Health Journal","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126137437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the efficacy of uterine artery Doppler in predicting the response to Mefenamic Acid during treatment of women having IUCD associated menorrhagia","authors":"H. Sammour, S. Ashoush, O. Ibrahim, Y. Essam","doi":"10.21608/EBWHJ.2019.19364.1054","DOIUrl":"https://doi.org/10.21608/EBWHJ.2019.19364.1054","url":null,"abstract":"Background: Bleeding with IUCDs is considered iatrogenic dysfunctional uterine bleeding. The bleeding associated with IUCD use may either occur during menstruation (heavy and/or prolonged) or in the form of intermenstrual bleeding and spotting.Patients and Methods:This study was carried out on 156 women attended the family planning out-patient clinic in the Obstetrics and Gynecology Department, Ain-Shams University Hospitals, during the period from May 2017 to May 2018. Patients were divided according to the response to treatment into two groups: Group (I): Responders to treatment with Mefenamic acid and Group (II): Non-responders to treatment with Mefenamic acid. Response to treatment was evaluated according to: Pictorial blood loss assessment chart.Results: Interpretation of the results of this work showed that uterine artery mean value of the PI of the women who responded to treatment with Mefenamic acid (group I) (1.54±0.42) were significantly higher than mean value of PI of women who didn’t respond to treatment with Mefenamic acid (group II) (0.96±0.28), also showed that uterine artery mean value of the RI of the who responded to treatment with Mefenamic acid (group I) (1.01±0.25) were significantly higher than mean values of RI of women who didn’t respond to treatment with Mefenamic acid (group II) (0.71±0.21). Doppler indices showed that pulsatility index ≥ 1.27 had moderate sensitivity (75.3%) and NPV (75.3%) but high specificity (90.1%) and PPV (90.1%) in prediction of responders. Resistive index ≥ 0.93 had low sensitivity (69.4%) and NPV (70.8%) but moderate specificity (88.7%) and PPV (88.1%) in prediction of responders.Conclusion:There is a strong relationship between uterine artery Doppler indices and prediction of response to Mefenamic acid.","PeriodicalId":224226,"journal":{"name":"Evidence Based Womenʼs Health Journal","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116264336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between Serum Anti-Müllerian Hormone Levels and Antral follicle count in prediction of clinical pregnancy in women with unexplained infertility undergoing ICSI cycles","authors":"Wafaa Taha, M. E. M. Mohamed, D. Mansour, A. Awad","doi":"10.21608/EBWHJ.2020.19205.1049","DOIUrl":"https://doi.org/10.21608/EBWHJ.2020.19205.1049","url":null,"abstract":"","PeriodicalId":224226,"journal":{"name":"Evidence Based Womenʼs Health Journal","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127879002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Increased Maternal Body Mass Index on Pregnancy Outcome A Comparative, Prospective Study","authors":"M. Eweis, E. Farid, Ahmed Gawain, R. Ramadan","doi":"10.21608/EBWHJ.2021.42917.1107","DOIUrl":"https://doi.org/10.21608/EBWHJ.2021.42917.1107","url":null,"abstract":"","PeriodicalId":224226,"journal":{"name":"Evidence Based Womenʼs Health Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116254377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of intramyometrial injection of epinephrine during abdominal myomectomy","authors":"Z. Abouzeid","doi":"10.21608/EBWHJ.2018.5540.1007","DOIUrl":"https://doi.org/10.21608/EBWHJ.2018.5540.1007","url":null,"abstract":"","PeriodicalId":224226,"journal":{"name":"Evidence Based Womenʼs Health Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130894660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}