Japanese Journal of Complementary and Alternative Medicine最新文献

{"title":"Effects of Consuming A Supplement with Antioxidant Action on Physical Fatigue and Sports Performance","authors":"A. Sudo, Kenji Yamada, K. Yazawa","doi":"10.1625/JCAM.16.21","DOIUrl":"https://doi.org/10.1625/JCAM.16.21","url":null,"abstract":"Effects of Consuming A Supplement with Antioxidant Action on Physical Fatigue and Sports Performance Akiharu SUDO, Kenji YAMADA, Kazunaga YAZAWA 1 Faculty of Physical Education, Kokushikan University 2 Lecturer Faculty of Physical Education , Kokushikan University 3 Waseda University Research Organization for Nano & Life Innovation Objectives: The current study examined a supplement (denoted here as V7) containing astaxanthin, reduced coenzyme Q10, leucine, arginine, citrulline, DHA, and krill oil and a placebo containing only salad oil. This study examined the subjective level of fatigue and the performance level while subjects consumed the supplement or the placebo for 30 day. Methods: Subjects were 19 members of the women’s softball club at a physical education university. Results: Results indicated that leg fatigue, the state of the back, dark spots on the skin, and performance on a 50-m sprint improved significantly after consuming V7 in comparison to values prior to consumption. Scores for a total of 6 items—leg fatigue, the state of the hips, the state of the back, skin blotches, and eye strain—improved significantly after consuming V7 in comparison to values prior to consumption. Conclusion: These findings presumably indicate that DHA (an essential fatty acid) and krill oil (krill are rich in the ω3 polyunsaturated fatty acids DHA and EPA) in phospholipid form are taken up by the cell membrane. The 2 substances enhance cell and tissue function in the body by prompting cells to take up nutrients and quickly eliminate waste products. Moreover, reduced coenzyme Q10 had 2 actions—“production of energy” and “antioxidant action” that inhibited physical deterioration— while astaxanthin had “antioxidant action.” This antioxidant action, anti-fatigue action, antiinflammatory action, enhanced immunity, and enhanced endurance synergistically acted to alleviate general fatigue. Moreover, muscle protein synthesis stimulated by leucine, arginine, and citrulline alleviated muscle fatigue in the legs, knees, hips, and back, presumably accounting for the improved time on the 50-m sprint.","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124177740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Peucedanum japonicum Thunb on Body Composition and Biochemical Examination of Blood","authors":"M. Sakaue, A. Yasueda, Toshinori Ito, S. Ohno","doi":"10.1625/JCAM.15.121","DOIUrl":"https://doi.org/10.1625/JCAM.15.121","url":null,"abstract":"Metabolic syndrome is defined as a condition characterized by obesity due to visceral fat accumulation and ≥2 of the following symptoms: hyperglycemia, hypertension, and dyslipidemia. Metabolic syndrome may trigger arteriosclerotic diseases such as diabetes, hypertension, dyslipidemia, heart disease, and stroke. Therefore, prevention and treatment of metabolic syndrome are urgent issues. Since it has been reported that excessive nutrient intake and unhealthy lifestyles may contribute to metabolic syndrome, various approaches have been introduced into the medical administration system and performed; for example, preventive and therapeutic dietary counseling and nutritional therapy for the purpose of reducing of visceral fat. Recently, the pharmacological effects of foods have been noted and a study on \"functional foods\" has been promoted in countries worldwide. It has been reported that approximately 60% of Japanese adults routinely use functional foods with expectations of health maintenance, disease prevention, or the amelioration of symptoms. However, it is limited functional foods of which effect on improvement of metabolic syndrome has been demonstrated by clinical trials in human. Therefore, it is thought that the evidence of functional foods should be established immediately. 【ABSTRACT】 Peucedanum japonicum Thunb (PJT) has reported the effect of l ipid and glucose metabolism at some in vivo and in vitro study. In this study, 21 subjects with dyslipidemia border zone took PJT for 12 weeks. The changes over t ime of body composition and biochemical test were examined. The values of HbA1c were significantly reduced compared to the values before intake. For body fat percentage, the value at 8 weeks after intake showed a significant decrease compared with the value before intake. Adiponectin was significantly increase after 8 weeks in obese subject. These results suggested PJT may improvement of glucose metabolism.","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124017137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Coix-seed Reactive Derivatives (CRD) on Cytochrome P450 Isoforms CYP3A4, CYP2D6, CYP2C9 In Vitro","authors":"N. Suzuki, H. Kyo, K. Uebaba, T. Ohta","doi":"10.1625/JCAM.15.109","DOIUrl":"https://doi.org/10.1625/JCAM.15.109","url":null,"abstract":"CRD, a Coix-seed Reactive Derivatives, has a novel mechanism in the treatment of various diseases. In the present study, a fluorometric-based high throughput method using cytochrome P450 (CYP)screening kit was adopted to evaluate in vitro inhibition potential of CRD (CRD 1 and CRD 2) on CYP isoenzymes by calculating remaining enzyme activities and inhibitory potential (IC50 values) using the determined values of fluorescence intensity. IC50 of CRD 1 and CRD 2 were as follows: CYP3A4; >500 µg/ml, 490 µg/ml, CYP2D6; >500 µg/ml，>500 µg/ml，CYP2C9; >500 µg/ml，339 µg/ml, respectively. The result showed that CRD exhibited little activity in the inhibition of CYP3A4, CYP2D6 and CYP2C9.","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124673861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coix-seed Reactive Derivatives(CRD): An Observational study","authors":"N. Suzuki, H. Kyo","doi":"10.1625/JCAM.15.127","DOIUrl":"https://doi.org/10.1625/JCAM.15.127","url":null,"abstract":"Coix-seed Reactive Derivatives (CRD) : An Observational study Nobutaka SUZUKI, Hoko KYO Department of Complementary and Alternative Medicine Clinical research and Development, Kanazawa University Graduate School of Medical Science Functional food research encompasses several types of study designs, including observational studies and randomized clinical trials (RCTs). To clarify the functions of Coix-seed Reactive Derivatives(CRD), we observed 7 refractory skin diseases: case1 Pustulosis palmaris et plantaris, case2 atopic dermatitis, case3 hand eczema, case4 contact dermatitis, case5 wrinkles of a face, case6 acne vulgaris and case7 lentigo senilis(senile pigment freckle). Although CRD intake seemed to be effective in all cases, further studies are needed to define the optimal dose and duration.","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115009311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Coix Seed with Husks on Bovine Cutaneous Papillomas","authors":"N. Suzuki, Takuya Kawashima, H. Kyo, K. Uebaba","doi":"10.1625/JCAM.15.117","DOIUrl":"https://doi.org/10.1625/JCAM.15.117","url":null,"abstract":"Effect of Coix Seed with Husks on Bovine Cutaneous Papillomas Nobutaka SUZUKI, Takuya KAWASHIMA, Hoko KYO, Kazuo UEBABA Department of Complementary and Alternative Medicine Clinical Research and Development, Kanazawa University Graduate School of Medical Science Aozora Dermatology Clinic Teikyo Heisei University We evaluated the effect of Coix seed with husks on bovine cutaneous papillomas. Boiled coix seed with husks was administered to two cows with intractable cutaneous papillomas. The nodules disappeared or diminished on week 6. Further examination will be needed to confirm these findings.","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129065635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep Sea Water in the Field of Mibyo and Preventive Medicine：A Japanese Perspective","authors":"Tatsuki Yamamoto, Katsuhisa Yamada, N. Suzuki, H. Kyo, M. Takahashi","doi":"10.1625/JCAM.15.67","DOIUrl":"https://doi.org/10.1625/JCAM.15.67","url":null,"abstract":"Deep Sea Water in the Field of Mibyo and Preventive Medicine: A Japanese Perspective Tatsuki YAMAMOTO, Katsuhisa YAMADA, Nobutaka SUZUKI, Hoko KYO, Masayuki Mac TAKAHASHI Deep Sea Water Laboratory, DHC Corporation Department of Complementary and Alternative Medicine Clinical Research and Development, Kanazawa University Graduate School of Medical Science Emeritus Professor of Tokyo University Deep Ocean Water Applications Society Deep sea water is sea water below a depth of 200 m. Japan is the leading country in the world on industrial applications of deep sea water, which has characteristics such as cleanliness, and is rich in various kinds of minerals and inorganic nutrients compared to surface seawater. In addition, applications of deep sea water as a useful resource have become a world interest, especially in fields of presymptomatic diseases called mibyo and in preventive medicine. Evidence of deep sea water applications in experimental and clinical medicine of the following diseases, lifestyle diseases such as dyslipidemia, high blood pressure, diabetes and arteriosclerosis and atopic dermatitis, osteoporosis, cancer, peptic ulcer, cataracts and constipation are given particular attention in this review.","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122359767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coix-seed Reactive Derivatives (CRD)の皮膚色素沈着に与える影響に関する研究","authors":"信孝 鈴木, 拓也 川島, 鳳浩 許, 和夫 上馬塲","doi":"10.1625/JCAM.15.85","DOIUrl":"https://doi.org/10.1625/JCAM.15.85","url":null,"abstract":"Effect of Coix-seed Reactive Derivatives (CRD) on Skin Pigmentation : A Randomized Controlled Trial Nobutaka SUZUKI, Takuya KAWASHIMA, Hoko KYO, Kazuo UEBABA Department of Complementary and Alternative Medicine Clinical Research and Development, Kanazawa University Graduate School of Medical Science Aozora Dermatology Clinic Teikyo Heisei University We evaluated the effects of the extract of Coix-seed Reactive Derivatives (CRD) on female skin pigmentation. Ninety females with facial pigmentation were assigned randomly to 3 groups and CRD (2g/day, 4g/day or placebo) was administrated for 8weeks. We confirmed the safety of CRD, and both the rate of change of facial pigmentation and erythema in 4g/day group decreased significantly (p<0.01). Further studies are needed to define the optimal dose of CRD.","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122905756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distribution of Fat Droplets in Liver Tissue of Rats Fed a Diet with Different Fatty Acid Compositions","authors":"Yasue Hosoyamada, Masako Yamada","doi":"10.1625/JCAM.15.79","DOIUrl":"https://doi.org/10.1625/JCAM.15.79","url":null,"abstract":"Distribution of Fat Droplets in Liver Tissue of Rats Fed a Diet with Different Fatty Acid Compositions Yasue HOSOYAMADA, Masako YAMADA Department of Nutrition, Faculty of Health Care Sciences, Chiba Prefectural University of Health Sciences Objectives: We examined the effect of oil intake differing in fatty acid composition on fat accumulation amount, concentration of serum and fat droplets adipocytes of liver tissue in rats. Methods: Young male rats were fed a high cholesterol diet containing either lard, soybean oil, perilla oil or fish oil for 4wk. The control diet contained a lard component. Results: Posterior abdominal wall fat and testicle peripheral fat weights were significantly lower in the fish oil group compared with the control and the soybean oil group. The number of fat droplets was significantly higher in the liver tissue of rats in the perilla oil group compared with the other groups, and many fat droplets with small diameters were observed. The proportion of fat droplets to the total area was significantly lower in the perilla oil group and the fish oil group compared with the control and the soybean oil group. Conclusion: The results suggested that oil intake differing in fatty acid composition correlates with fat accumulation amount and lipid droplet area in the liver tissue. Fish oil intake correlated with reduced visceral fat accumulation and is expected to be useful in the prevention and improvement of obesity.","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121502177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Viewpoint Regarding the Use of Coix Seed During Pregnancy","authors":"N. Suzuki","doi":"10.1625/JCAM.15.141","DOIUrl":"https://doi.org/10.1625/JCAM.15.141","url":null,"abstract":"【要旨】 妊娠中のハトムギ使用について解説した.市販のハトムギ茶を妊娠中に摂取して流産や早産になるという証拠はなく,産後に 市販のハトムギ茶摂取を禁ずる科学的根拠もない.したがって,妊婦が常識の範囲内でハトムギ茶を飲用もしくはハトムギ調 理品を食することは,問題ないと考えた.ただし,ハトムギ摂取に過敏になっている妊婦は,無理にハトムギ飲食を行う必要 はない.また,妊娠中のハトムギ摂取に関しては医師に相談することが肝要である.妊娠中のハトムギの製薬であるヨクイニ ンの内服については,必ず産婦人科医師の管理のもとに行うべきである.また,ハトムギの栄養補助食品も,妊娠中は中止す るか,もしくは医師と相談の上で使用するのが望ましい.ただし,妊娠中にこれらの医薬品や食品を飲み続け,流産,早産, 児の奇形等が発症したとする報告はない.妊娠中はハトムギ摂取を控えるべきであるという伝承については,ハトムギに麦角 菌が感染し,産生された麦角アルカロイドによる子宮収縮が深く関与していたという仮説を立てた.また,小麦・大麦・ライ麦, トウモロコシなど麦角菌に感染する可能性のあるイネ科植物の麦角アルカロイド汚染の有無を知ることは,妊婦の流産・早産 予防上,重要であることも指摘した.","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"57 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121439449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of Coix-seed Reactive Derivatives (CRD) Intake on Th1/Th2 Balance in Healthy Adults: A Preliminary Research","authors":"N. Suzuki, H. Kyo, K. Uebaba","doi":"10.1625/jcam.15.113","DOIUrl":"https://doi.org/10.1625/jcam.15.113","url":null,"abstract":"The Influence of Coix-seed Reactive Derivatives (CRD) Intake Evidence that Coix-seed Reactive Derivatives (CRD) intake might be effective for allergic conditions is gradually accumulated. Therefore, we studied the influence of CRD intake on Th1/Th2 Balance. Eight Healthy Adults were orally administrated CRD 6g/ day for 4 weeks, and we measured the value of blood Th1/Th2. Th2 and Th0 decreased significantly, and Th1/Th2 relatively increased (not significant). Further studies are needed to define the immunomodulatory effects of CRD.","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"129 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122449969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}