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Japanese Journal of Complementary and Alternative Medicine最新文献

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Inhibitory Effects of Watercress on Tumor Promotion in a Mouse Model of Two-stage Skin Carcinogenesis 豆瓣菜对两期皮肤癌变小鼠模型肿瘤促进的抑制作用
Japanese Journal of Complementary and Alternative Medicine Pub Date : 2016-03-31 DOI: 10.1625/JCAM.13.1
K. Yasukawa, H. Kanno, S. Kitanaka, Y. Yanagimoto
{"title":"Inhibitory Effects of Watercress on Tumor Promotion in a Mouse Model of Two-stage Skin Carcinogenesis","authors":"K. Yasukawa, H. Kanno, S. Kitanaka, Y. Yanagimoto","doi":"10.1625/JCAM.13.1","DOIUrl":"https://doi.org/10.1625/JCAM.13.1","url":null,"abstract":"Cancer prevention is one of the most urgent problems in the field of public health worldwide. The methanol extract of watercress ( Nasturtium officinale) inhibits 12-O -tetradecaonoylphorbol-13-acetate (TPA)-induced ear edema in mice. The extract also exhibits marked antitumor activity in in vivo two-stage carcinogenesis test in mice using 7,12-dimethylbenz[ α ]anthracene as an initiator and TPA as a promoter. From the active fraction of the methanol extract, sitosterol 3-O -glucopyranoside (1) was isolated and identified. This compound was evaluated for its inhibitory effects on TPA-induced inflammation (1 µg/ear) in mice, and had a 50% inhibitory dose of 299 nmol/ear. These results indicate that watercress extracts are useful in cancer prevention.","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125286836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Immune Efficacy and Safety of Fucoidan Extracted from Gagome Kombu (Kjellmaniella crassifolia) in Healthy Japanese Subjects 海带岩藻多糖提取物对日本健康人的免疫效果及安全性
Japanese Journal of Complementary and Alternative Medicine Pub Date : 2015-09-30 DOI: 10.1625/JCAM.12.87
H. Ohnogi, Y. Naito, Yasuki Higashimura, K. Uno, T. Yoshikawa
{"title":"Immune Efficacy and Safety of Fucoidan Extracted from Gagome Kombu (Kjellmaniella crassifolia) in Healthy Japanese Subjects","authors":"H. Ohnogi, Y. Naito, Yasuki Higashimura, K. Uno, T. Yoshikawa","doi":"10.1625/JCAM.12.87","DOIUrl":"https://doi.org/10.1625/JCAM.12.87","url":null,"abstract":"Fucoidan, a sulfated polysaccharide extracted from various brown alga, such as Kombu, Wakame, and Mozuku, has a complex chemical structure composed of partially sulfated fucose as the major sugar and other sugars, including mannose, galactose, xylose, and uronic acid. Recent studies have reported that fucoidan structure and content differ according to origins of the algae. Gagome kombu (Kjellmaniella crassifolia ) is an edible brown seaweed grown around the southern area of Hokkaido, Japan and contains an abundance of fucoidan. Sakai et al. isolated fucoidan-degrading enzymes from marine bacteria and identified the chemical structure of fucoidan from Gagome kombu (GKF) by nuclear magnetic resonance imaging and mass spectrometry analyses of enzymatic degradation products. Structural analysis revealed that GKF is a polysaccharide that is more sulfated compared with those from other brown algae and consists of three major fucoidans: F-, U-, G-fucoidan. Many studies have reported multiple biological activities of fucoidan, including anti-coagulant, antivirus, and anti-cancer activities. We previously JJCAM. 2015 September;12 (2):87-93","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115188634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
黒ショウガ由来メトキシフラボン混合物(I)の安全性評価；マウスによる28日間反復経口投与試験・小核試験 来自黑姜的甲氧基黄酮混合物(I)的安全性评价;小鼠28天反复口服试验-小核试验
Japanese Journal of Complementary and Alternative Medicine Pub Date : 2015-09-30 DOI: 10.1625/JCAM.12.79
浩孝 大桑（林）, 貴則 藤田, 拓也 河田, 長久 中野, 富久 太田
{"title":"黒ショウガ由来メトキシフラボン混合物(I)の安全性評価；マウスによる28日間反復経口投与試験・小核試験","authors":"浩孝 大桑（林）, 貴則 藤田, 拓也 河田, 長久 中野, 富久 太田","doi":"10.1625/JCAM.12.79","DOIUrl":"https://doi.org/10.1625/JCAM.12.79","url":null,"abstract":"","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125557858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tabebuia avellanedae（タヒボ）を摂取した食道癌の１例 服用Tabebuia avellanedae的食道癌病例
Japanese Journal of Complementary and Alternative Medicine Pub Date : 2015-09-30 DOI: 10.1625/JCAM.12.107
正明 畠中, 陽一 福田
{"title":"Tabebuia avellanedae（タヒボ）を摂取した食道癌の１例","authors":"正明 畠中, 陽一 福田","doi":"10.1625/JCAM.12.107","DOIUrl":"https://doi.org/10.1625/JCAM.12.107","url":null,"abstract":"","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124398208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
アガリクス (Agaricus blazei Murill ) 粉末食品の安全性と有効性に関するランダム化ヒト試験 阿格里克斯(Agaricus blazei Murill)粉末食品的安全性和有效性的随机人类试验
Japanese Journal of Complementary and Alternative Medicine Pub Date : 2015-09-30 DOI: 10.1625/JCAM.12.95
和夫 上馬塲, 鳳浩 許, 信孝 鈴木, 哲郎 浦田
{"title":"アガリクス (Agaricus blazei Murill ) 粉末食品の安全性と有効性に関するランダム化ヒト試験","authors":"和夫 上馬塲, 鳳浩 許, 信孝 鈴木, 哲郎 浦田","doi":"10.1625/JCAM.12.95","DOIUrl":"https://doi.org/10.1625/JCAM.12.95","url":null,"abstract":"","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123227735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
黒酢含有食品による血圧，QOL，体質への効果 含有黑醋的食品对血压、QOL、体质的效果
Japanese Journal of Complementary and Alternative Medicine Pub Date : 2014-09-01 DOI: 10.1625/JCAM.11.95
N. Hamadate, Houkou Kyo, Y. Matsumoto, M. Shikura, Chiemi Mizukami, K. Seto, Kazuo Uebaba, Nobutaka Suzuki
{"title":"黒酢含有食品による血圧，QOL，体質への効果","authors":"N. Hamadate, Houkou Kyo, Y. Matsumoto, M. Shikura, Chiemi Mizukami, K. Seto, Kazuo Uebaba, Nobutaka Suzuki","doi":"10.1625/JCAM.11.95","DOIUrl":"https://doi.org/10.1625/JCAM.11.95","url":null,"abstract":"Effects of Dietary Supplement Containing Kurozu Concentrate on Blood Pressure, QOL and TCM Constitution Naobumi HAMADATE1, Houkou KYO2, Yoshiyuki MATSUMOTO1, Mami SHIKURA1, Chiemi MIZUKAMI1, Kayoko SETO1, Kazuo UEBABA3, Nobutaka SUZUKI2 1 Department of Research and Development, Egao Co. Ltd. 2 Department of Complementary and Alternative Medicine Clinical Research and Development, Kanazawa University Graduate School of Medical Science 3 Department of Human Care, Institute of Eastern Medicine, Teikyo Heisei University Objectives: The present study was examined the effects of dietary supplement containing Kurozu concentrate on Blood Pressure, QOL and Traditional Chinese Medicine (TCM) Constitution. Methods: Forty subjects with slightly high blood pressure were assigned randomly to 2 groups (active group and placebo group). Kurozu-containing foods or the placebo was administered to the subjects daily for 12 weeks. At week 0, 6 and 12, blood samples were collected, physical measurements were taken, and the quality of life (SF-36v2) and TCM constitution were examined. Results: Significant differences on blood pressure and TCM constitution between the groups were observed at week 12. The change of QOL between the groups was observed significantly at week 6. Conclusion: These findings suggest that foods containing Kurozu have hypotensive action and improve effects on constitutional problems. In addition, it was confirmed that foods containing Kurozu are safe to ingest.","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125272961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2 型糖尿病マウスの肝臓における霊芝菌糸体培養培地抽出物 (WER) の糖質代謝に与える影響 2型糖尿病对小鼠肝脏中灵芝菌丝培养基提取物(WER)糖分代谢的影响
Japanese Journal of Complementary and Alternative Medicine Pub Date : 2014-03-01 DOI: 10.1625/JCAM.11.57
伸也 神内, 由梨 新藤, 有香 内海, 直洋 岩田, 真理 岡﨑, 史子 鈴木, 博 飯塚, 哲 浅野, 広和 松崎, 康英 日比野
{"title":"2 型糖尿病マウスの肝臓における霊芝菌糸体培養培地抽出物 (WER) の糖質代謝に与える影響","authors":"伸也 神内, 由梨 新藤, 有香 内海, 直洋 岩田, 真理 岡﨑, 史子 鈴木, 博 飯塚, 哲 浅野, 広和 松崎, 康英 日比野","doi":"10.1625/JCAM.11.57","DOIUrl":"https://doi.org/10.1625/JCAM.11.57","url":null,"abstract":"","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114901571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
ヒアルロニダーゼ，コラゲナーゼ，チロシナーゼ，ウレアーゼ阻害活性を有する機能性食品素材や薬用化粧品の活性成分としてのアカギの有用性について 关于赤木作为具有透明质酸酶、胶质酶、酪氨酸酶、氨基甲酸酶抑制活性的功能性食品素材和药用化妆品活性成分的有效性
Japanese Journal of Complementary and Alternative Medicine Pub Date : 2010-09-01 DOI: 10.1625/JCAM.7.129
バルラ フローリン, 朝子 堀西, 直樹 原田, 亮一 山地, 俊樹 榎本, 信孝 鈴木, 久行 前中, 長久 中野
{"title":"ヒアルロニダーゼ，コラゲナーゼ，チロシナーゼ，ウレアーゼ阻害活性を有する機能性食品素材や薬用化粧品の活性成分としてのアカギの有用性について","authors":"バルラ フローリン, 朝子 堀西, 直樹 原田, 亮一 山地, 俊樹 榎本, 信孝 鈴木, 久行 前中, 長久 中野","doi":"10.1625/JCAM.7.129","DOIUrl":"https://doi.org/10.1625/JCAM.7.129","url":null,"abstract":"Bischofia javanica leaf extract exhibited inhibitory activities against hyaluronidase, collagenase, tyrosinase and urease, suggesting that it is useful as an active ingredient for functional foods and cosmeceutical products. In particular, its 50% inhibitory concentration for hyaluronidase was comparable to that of disodium cromoglycate, which is a well-known hyaluronidase inhibitor used as an anti-inflammation and anti-allergy agent. In addition, the extract also inhibited urease with the almost the same potential as acetohydroxamic acid, which is reported to suppress Helicobacter pylori-induced gastritis by inhibiting urease.","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134516591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
新開発 LED 照明の室内環境快適性に及ぼす効果（第 3 報） 新开发LED照明对室内环境舒适性的影响(第3报)
Japanese Journal of Complementary and Alternative Medicine Pub Date : 1900-01-01 DOI: 10.1625/JCAM.10.25
修身 梶本, 幸茂 白市, 昭 栗山, 雅生 大塚, 孝徳 門脇, 友啓 杉野
{"title":"新開発 LED 照明の室内環境快適性に及ぼす効果（第 3 報）","authors":"修身 梶本, 幸茂 白市, 昭 栗山, 雅生 大塚, 孝徳 門脇, 友啓 杉野","doi":"10.1625/JCAM.10.25","DOIUrl":"https://doi.org/10.1625/JCAM.10.25","url":null,"abstract":"","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"131 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115617693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Astaxanthin for Complementary and Alternative Medicine 虾青素的补充和替代医学
Japanese Journal of Complementary and Alternative Medicine Pub Date : 1900-01-01 DOI: 10.1625/JCAM.5.173
H. Itakura, Jirou Takahashi, Akitoshi Kitamura
{"title":"Astaxanthin for Complementary and Alternative Medicine","authors":"H. Itakura, Jirou Takahashi, Akitoshi Kitamura","doi":"10.1625/JCAM.5.173","DOIUrl":"https://doi.org/10.1625/JCAM.5.173","url":null,"abstract":"アスタキサンチンは，広く天然に存在する赤色のカロテノイドの一種であり，一重項酸素消去および抗脂質過酸化活性などの優れた抗酸化作用を有する．近年さまざまな生理活性が報告されるようになり，健康食品および化粧品素材として普及しつつ，予防医学の領域においても注目されている．本稿では，アスタキサンチンの由来，他のカロテノイドとの比較，化学的特長に触れつつ，抗脂質過酸化活性，抗炎症，血流改善，メタボリックシンドローム改善，眼精疲労改善，ピロリ菌抑制，脂質代謝改善，筋肉疲労改善，美肌効果，男性不妊症改善などの機能性，さらに体内動態および安全性についての細胞，動物試験，および臨床試験などの結果を取り上げ，補完代替医療素材としての可能性を紹介する．","PeriodicalId":224142,"journal":{"name":"Japanese Journal of Complementary and Alternative Medicine","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117192315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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